Gene Symbol | Ythdc2 |
Entrez Gene ID | 240255 |
Full Name | YTH domain containing 2 |
Synonyms | 3010002F02Rik,BC037178 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Ythdc2 cDNA ORF clone
Gene Symbol | Ythdc2 |
Entrez Gene ID | 240255 |
Full Name | YTH domain containing 2 |
Synonyms | 3010002F02Rik,BC037178 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001163013.1 | NP_001156485.1 | 3'-5' RNA helicase YTHDC2 |
XM_030250454.1 | XP_030106314.1 | 3'-5' RNA helicase YTHDC2 isoform X1 |
XM_006525915.2 | XP_006525978.1 | probable ATP-dependent RNA helicase YTHDC2 isoform X1 |
XM_006525915.3 | XP_006525978.1 | 3'-5' RNA helicase YTHDC2 isoform X2 |
Mus musculus (house mouse) | Ythdc2 | NP_001156485.1 |
Arabidopsis thaliana (thale cress) | NIH | NP_172152.1 |
Homo sapiens (human) | YTHDC2 | NP_073739.3 |
Bos taurus (cattle) | YTHDC2 | NP_001179740.1 |
Rattus norvegicus (Norway rat) | Ythdc2 | XP_003749024.1 |
Gallus gallus (chicken) | YTHDC2 | XP_413970.2 |
Pan troglodytes (chimpanzee) | YTHDC2 | XP_517881.2 |
Canis lupus familiaris (dog) | LOC474641 | XP_005626411.1 |
Arabidopsis thaliana (thale cress) | HVT1 | NP_850154.2 |
Xenopus tropicalis (tropical clawed frog) | ythdc2 | XP_002936459.2 |
Oryza sativa (rice) | Os01g0767700 | NP_001044362.1 |
YTHDC2 | XP_002804526.1 | |
Danio rerio (zebrafish) | LOC567114 | XP_695496.6 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP007953 | XP_555531.3 |
Jain D, Puno MR, Meydan C, Lailler N, Mason CE, Lima CD, Anderson KV, Keeney S
eLife7(2018 Jan)
The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline.
Bailey AS, Batista PJ, Gold RS, Chen YG, de Rooij DG, Chang HY, Fuller MT
eLife6(2017 Oct)
Regulation of m
Wojtas MN, Pandey RR, Mendel M, Homolka D, Sachidanandam R, Pillai RS
Molecular cell68(2)374-387.e12(2017 Oct)
Ythdc2 is an N
Hsu PJ, Zhu Y, Ma H, Guo Y, Shi X, Liu Y, Qi M, Lu Z, Shi H, Wang J, Cheng Y, Luo G, Dai Q, Liu M, Guo X, Sha J, Shen B, He C
Cell research27(9)1115-1127(2017 Sep)
Meioc maintains an extended meiotic prophase I in mice.
Soh YQS, Mikedis MM, Kojima M, Godfrey AK, de Rooij DG, Page DC
PLoS genetics13(4)e1006704(2017 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
studies reveal a role for YTHDC2 in modulating the levels of m(6)A-modified germline transcripts to maintain a gene expression program that is conducive for progression through meiosis.
Title: Regulation of m
We conclude that when the meiotic chromosomal program is initiated, Meioc is simultaneously induced so as to extend meiotic prophase. Specifically, MEIOC, together with YTHDC2, promotes a meiotic (as opposed to mitotic) cell cycle program via post-transcriptional control of their target transcripts.
Title: Meioc maintains an extended meiotic prophase I in mice.
The following Ythdc2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ythdc2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu54571 | |
Clone ID Related Accession (Same CDS sequence) | XM_006525915.2 , XM_006525915.3 | |
Accession Version | XM_006525915.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2670bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | probable ATP-dependent RNA helicase YTHDC2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006525915.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTTTAG ATTGGGCTAA GCACTTTGGA CAGACTGAAA TTGTGGATCT TCTAGAATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006525978.1 |
CDS | 89..2758 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006525915.2 |
1 | ATGGCTTTAG ATTGGGCTAA GCACTTTGGA CAGACTGAAA TTGTGGATCT TCTAGAATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu54571 | |
Clone ID Related Accession (Same CDS sequence) | XM_006525915.2 , XM_006525915.3 | |
Accession Version | XM_006525915.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2670bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | 3'-5' RNA helicase YTHDC2 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006525915.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTTTAG ATTGGGCTAA GCACTTTGGA CAGACTGAAA TTGTGGATCT TCTAGAATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006525978.1 |
CDS | 77..2746 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006525915.3 |
1 | ATGGCTTTAG ATTGGGCTAA GCACTTTGGA CAGACTGAAA TTGTGGATCT TCTAGAATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu87394 | |
Clone ID Related Accession (Same CDS sequence) | XM_030250454.1 | |
Accession Version | XM_030250454.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3393bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | 3'-5' RNA helicase YTHDC2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCAGGTG ATAGCACATT GTCAACTGTG ACCCATGTTA TTGTGGATGA AGTGCATGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030106314.1 |
CDS | 751..4143 |
Translation |
Target ORF information:
Target ORF information:
|
XM_030250454.1 |
1 | ATGGCAGGTG ATAGCACATT GTCAACTGTG ACCCATGTTA TTGTGGATGA AGTGCATGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu08687 | |
Clone ID Related Accession (Same CDS sequence) | NM_001163013.1 | |
Accession Version | NM_001163013.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 4338bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-10 | |
Organism | Mus musculus(house mouse) | |
Product | 3'-5' RNA helicase YTHDC2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC137150.11 and AC134472.4. On or before Jul 8, 2009 this sequence version replaced XM_910737.2, XM_140310.8. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC138263.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849390, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGTCCAGGC CGAGCAGCGT CTCGCCGCGT CCGCCGGCTC CTAGCGGAGG CGGCACGGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001156485.1 |
CDS | 23..4360 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001163013.1 |
1 | ATGTCCAGGC CGAGCAGCGT CTCGCCGCGT CCGCCGGCTC CTAGCGGAGG CGGCACGGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
|
The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline. |
Regulation of m |
Ythdc2 is an N |
Meioc maintains an extended meiotic prophase I in mice. |