| Gene Symbol | Psma6 |
| Entrez Gene ID | 26443 |
| Full Name | proteasome (prosome, macropain) subunit, alpha type 6 |
| Synonyms | IOTA |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
The following Psma6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Psma6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu15314 | |
| Clone ID Related Accession (Same CDS sequence) | NM_011968.3 | |
| Accession Version | NM_011968.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 741bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-27 | |
| Organism | Mus musculus(house mouse) | |
| Product | proteasome subunit alpha type-6 isoform 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY340104.1, BC086685.1 and AV265469.1. On Aug 12, 2009 this sequence version replaced NM_011968.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: DV074934.1, BU520349.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGTCCCGGG GTTCCAGCGC CGGTTTTGAC CGTCACATTA CTATCTTCTC TCCCGAGGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_036098.1 |
| CDS | 92..832 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_011968.3 |
1 | ATGTCCCGGG GTTCCAGCGC CGGTTTTGAC CGTCACATTA CTATCTTCTC TCCCGAGGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu69217 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001310583.1 | |
| Accession Version | NM_001310583.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 684bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-21 | |
| Organism | Mus musculus(house mouse) | |
| Product | proteasome subunit alpha type-6 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC159636.3. On Jul 16, 2015 this sequence version replaced XM_006515884.2. Transcript Variant: This variant (2) uses an alternate 5' terminal exon, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BU939377.1, BU937147.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849384 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGCCAGTC TCCGAAAAAA ATATGCTTTT AAGGCTATTA ACCAGGGTGG ACTTACATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001297512.1 |
| CDS | 88..771 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001310583.1 |
1 | ATGGCCAGTC TCCGAAAAAA ATATGCTTTT AAGGCTATTA ACCAGGGTGG ACTTACATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
TRIM5? associates with proteasomal subunits in cells while in complex with HIV-1 virions. |
Calcineurin stimulates the expression of inflammatory factors in RAW 264.7 cells by interacting with proteasome subunit alpha type 6. |
PAC1 gene knockout reveals an essential role of chaperone-mediated 20S proteasome biogenesis and latent 20S proteasomes in cellular homeostasis. |
Mapping the murine cardiac 26S proteasome complexes. |
In mouse myoblasts nuclear prosomes are associated with the nuclear matrix and accumulate preferentially in the perinucleolar areas. |
