Gene Symbol | Orai2 |
Entrez Gene ID | 269717 |
Full Name | ORAI calcium release-activated calcium modulator 2 |
Synonyms | A730041O15Rik,Tmem142b |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Orai2 cDNA ORF clone
Gene Symbol | Orai2 |
Entrez Gene ID | 269717 |
Full Name | ORAI calcium release-activated calcium modulator 2 |
Synonyms | A730041O15Rik,Tmem142b |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006504429.3 | XP_006504492.1 | protein orai-2 isoform X1 |
XM_006504429.4 | XP_006504492.1 | protein orai-2 isoform X2 |
XM_006504431.4 | XP_006504494.1 | protein orai-2 isoform X3 |
XM_006504430.4 | XP_006504493.1 | protein orai-2 isoform X3 |
XM_006504431.3 | XP_006504494.1 | protein orai-2 isoform X2 |
XM_006504431.2 | XP_006504494.1 | protein orai-2 isoform X1 |
XM_006504430.2 | XP_006504493.1 | protein orai-2 isoform X1 |
XM_030254545.1 | XP_030110405.1 | protein orai-2 isoform X1 |
NM_178751.3 | NP_848866.2 | protein orai-2 |
XM_006504430.3 | XP_006504493.1 | protein orai-2 isoform X2 |
Pan troglodytes (chimpanzee) | ORAI2 | XP_001155376.2 |
ORAI2 | XP_001108554.2 | |
Rattus norvegicus (Norway rat) | Orai2 | NP_001163874.1 |
Bos taurus (cattle) | ORAI2 | NP_001178277.1 |
Mus musculus (house mouse) | Orai2 | NP_848866.2 |
Homo sapiens (human) | ORAI2 | NP_001119812.1 |
Gallus gallus (chicken) | ORAI2 | NP_001025881.1 |
Xenopus tropicalis (tropical clawed frog) | orai1 | NP_001096448.1 |
Canis lupus familiaris (dog) | ORAI2 | XP_850105.1 |
Danio rerio (zebrafish) | orai2 | NP_001159919.1 |
ORAI2 modulates store-operated calcium entry and T cell-mediated immunity.
Vaeth M, Yang J, Yamashita M, Zee I, Eckstein M, Knosp C, Kaufmann U, Karoly Jani P, Lacruz RS, Flockerzi V, Kacskovics I, Prakriya M, Feske S
Nature communications814714(2017 Mar)
Store-operated Ca2+ entry regulates Ca2+-activated chloride channels and eccrine sweat gland function.
Concepcion AR, Vaeth M, Wagner LE 2nd, Eckstein M, Hecht L, Yang J, Crottes D, Seidl M, Shin HP, Weidinger C, Cameron S, Turvey SE, Issekutz T, Meyts I, Lacruz RS, Cuk M, Yule DI, Feske S
The Journal of clinical investigation126(11)4303-4318(2016 Nov)
Store-Operated Calcium Channel Complex in Postsynaptic Spines: A New Therapeutic Target for Alzheimer's Disease Treatment.
Zhang H, Sun S, Wu L, Pchitskaya E, Zakharova O, Fon Tacer K, Bezprozvanny I
The Journal of neuroscience : the official journal of the Society for Neuroscience36(47)11837-11850(2016 Nov)
A calcium-redox feedback loop controls human monocyte immune responses: The role of ORAI Ca2+ channels.
Saul S, Gibhardt CS, Schmidt B, Lis A, Pasieka B, Conrad D, Jung P, Gaupp R, Wonnenberg B, Diler E, Stanisz H, Vogt T, Schwarz EC, Bischoff M, Herrmann M, Tschernig T, Kappl R, Rieger H, Niemeyer BA, Bogeski I
Science signaling9(418)ra26(2016 Mar)
Upregulated expression of STIM2, TRPC6, and Orai2 contributes to the transition of pulmonary arterial smooth muscle cells from a contractile to proliferative phenotype.
Fernandez RA, Wan J, Song S, Smith KA, Gu Y, Tauseef M, Tang H, Makino A, Mehta D, Yuan JX
American journal of physiology. Cell physiology308(8)C581-93(2015 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
This study demonstrated that Transient Receptor Potential Canonical 6 (TRPC6) and Orai2 form stromal interaction molecule 2 (STIM2)-regulated neuronal-store-operated Ca(2+) influx (nSOC) channel complex in hippocampal synapse and the resulting Ca(2+) influx is critical for long-term maintenance of mushroom spines in hippocampal neurons.
Title: Store-Operated Calcium Channel Complex in Postsynaptic Spines: A New Therapeutic Target for Alzheimer's Disease Treatment.
results identified the ORAI-NOX2 feedback loop as a determinant of monocyte immune responses.
Title: A calcium-redox feedback loop controls human monocyte immune responses: The role of ORAI Ca2+ channels.
The data from this study indicate that upregulation of STIM2 and Orai2 is involved in the phenotypic transition of pulmonary arterial smooth muscle cells from a contractile state to a proliferative state.
Title: Upregulated expression of STIM2, TRPC6, and Orai2 contributes to the transition of pulmonary arterial smooth muscle cells from a contractile to proliferative phenotype.
Data indicate that the Ca(2+) release-activated Ca(2+) channels (CRAC) blocker GSK-7975A inhibited store-operated Ca(2+) entry in a concentration-dependent manner.
Title: Ca2+ release-activated Ca2+ channel blockade as a potential tool in antipancreatitis therapy.
The following Orai2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Orai2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu36151 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504429.3 , XM_006504429.4 | |
Accession Version | XM_006504429.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 795bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | protein orai-2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006504429.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAAGAAGG GAGAGACACA CAGACACAGC CTGGTCCCCA CCATGAGTGC AGAGCTCAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006504492.1 |
CDS | 438..1232 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006504429.3 |
1 | ATGAAGAAGG GAGAGACACA CAGACACAGC CTGGTCCCCA CCATGAGTGC AGAGCTCAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu07685 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504431.4 , XM_006504430.4 , XM_006504431.3 , XM_006504431.2 , XM_006504430.2 , NM_178751.3 , XM_006504430.3 | |
Accession Version | NM_178751.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 753bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-26 | |
Organism | Mus musculus(house mouse) | |
Product | protein orai-2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB640180.1, BC115648.1 and AC087420.4. On Jul 28, 2006 this sequence version replaced NM_178751.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK042940.1, AK079619.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGAGTGCAG AGCTCAATGT GCCCATGGAC CCCTCTGCCC CTGCCTGCCC TGAACCCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_848866.2 |
CDS | 133..885 |
Translation |
Target ORF information:
Target ORF information:
|
NM_178751.3 |
1 | ATGAGTGCAG AGCTCAATGT GCCCATGGAC CCCTCTGCCC CTGCCTGCCC TGAACCCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu07685 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504431.4 , XM_006504430.4 , XM_006504431.3 , XM_006504431.2 , XM_006504430.2 , NM_178751.3 , XM_006504430.3 | |
Accession Version | XM_006504431.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 753bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | protein orai-2 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006504431.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGTGCAG AGCTCAATGT GCCCATGGAC CCCTCTGCCC CTGCCTGCCC TGAACCCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006504494.1 |
CDS | 227..979 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006504431.4 |
1 | ATGAGTGCAG AGCTCAATGT GCCCATGGAC CCCTCTGCCC CTGCCTGCCC TGAACCCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu07685 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504431.4 , XM_006504430.4 , XM_006504431.3 , XM_006504431.2 , XM_006504430.2 , NM_178751.3 , XM_006504430.3 | |
Accession Version | XM_006504430.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 753bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | protein orai-2 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006504430.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGTGCAG AGCTCAATGT GCCCATGGAC CCCTCTGCCC CTGCCTGCCC TGAACCCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006504493.1 |
CDS | 283..1035 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006504430.4 |
1 | ATGAGTGCAG AGCTCAATGT GCCCATGGAC CCCTCTGCCC CTGCCTGCCC TGAACCCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu07685 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504431.4 , XM_006504430.4 , XM_006504431.3 , XM_006504431.2 , XM_006504430.2 , NM_178751.3 , XM_006504430.3 | |
Accession Version | XM_006504431.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 753bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | protein orai-2 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006504431.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGTGCAG AGCTCAATGT GCCCATGGAC CCCTCTGCCC CTGCCTGCCC TGAACCCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006504494.1 |
CDS | 215..967 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006504431.3 |
1 | ATGAGTGCAG AGCTCAATGT GCCCATGGAC CCCTCTGCCC CTGCCTGCCC TGAACCCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu07685 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504431.4 , XM_006504430.4 , XM_006504431.3 , XM_006504431.2 , XM_006504430.2 , NM_178751.3 , XM_006504430.3 | |
Accession Version | XM_006504431.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 753bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-02-08 | |
Organism | Mus musculus(House mouse) | |
Product | protein orai-2 isoform X1 | |
Comment |
1 | ATGAGTGCAG AGCTCAATGT GCCCATGGAC CCCTCTGCCC CTGCCTGCCC TGAACCCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006504494.1 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006504431.2 |
1 | ATGAGTGCAG AGCTCAATGT GCCCATGGAC CCCTCTGCCC CTGCCTGCCC TGAACCCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu07685 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504431.4 , XM_006504430.4 , XM_006504431.3 , XM_006504431.2 , XM_006504430.2 , NM_178751.3 , XM_006504430.3 | |
Accession Version | XM_006504430.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 753bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-02-08 | |
Organism | Mus musculus(House mouse) | |
Product | protein orai-2 isoform X1 | |
Comment |
1 | ATGAGTGCAG AGCTCAATGT GCCCATGGAC CCCTCTGCCC CTGCCTGCCC TGAACCCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006504493.1 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006504430.2 |
1 | ATGAGTGCAG AGCTCAATGT GCCCATGGAC CCCTCTGCCC CTGCCTGCCC TGAACCCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu07685 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504431.4 , XM_006504430.4 , XM_006504431.3 , XM_006504431.2 , XM_006504430.2 , NM_178751.3 , XM_006504430.3 | |
Accession Version | XM_006504430.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 753bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | protein orai-2 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006504430.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGTGCAG AGCTCAATGT GCCCATGGAC CCCTCTGCCC CTGCCTGCCC TGAACCCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006504493.1 |
CDS | 231..983 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006504430.3 |
1 | ATGAGTGCAG AGCTCAATGT GCCCATGGAC CCCTCTGCCC CTGCCTGCCC TGAACCCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu36151 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504429.3 , XM_006504429.4 | |
Accession Version | XM_006504429.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 795bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | protein orai-2 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006504429.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAAGAAGG GAGAGACACA CAGACACAGC CTGGTCCCCA CCATGAGTGC AGAGCTCAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006504492.1 |
CDS | 436..1230 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006504429.4 |
1 | ATGAAGAAGG GAGAGACACA CAGACACAGC CTGGTCCCCA CCATGAGTGC AGAGCTCAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu88930 | |
Clone ID Related Accession (Same CDS sequence) | XM_030254545.1 | |
Accession Version | XM_030254545.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1041bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | protein orai-2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGATAGCAC TTTGTGAAGT GAAGACCCCT AGATCTTGTA GGAGGGGTCG GTCCCCAACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030110405.1 |
CDS | 1753..2793 |
Translation |
Target ORF information:
Target ORF information:
|
XM_030254545.1 |
1 | ATGATAGCAC TTTGTGAAGT GAAGACCCCT AGATCTTGTA GGAGGGGTCG GTCCCCAACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
ORAI2 modulates store-operated calcium entry and T cell-mediated immunity. |
Store-operated Ca2+ entry regulates Ca2+-activated chloride channels and eccrine sweat gland function. |
Store-Operated Calcium Channel Complex in Postsynaptic Spines: A New Therapeutic Target for Alzheimer's Disease Treatment. |
A calcium-redox feedback loop controls human monocyte immune responses: The role of ORAI Ca2+ channels. |
Upregulated expression of STIM2, TRPC6, and Orai2 contributes to the transition of pulmonary arterial smooth muscle cells from a contractile to proliferative phenotype. |