Gene Symbol | Kdm3b |
Entrez Gene ID | 277250 |
Full Name | KDM3B lysine (K)-specific demethylase 3B |
Synonyms | 5830462I21Rik,JHDM2B,Jmjd1b,mKIAA1082 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Kdm3b cDNA ORF clone
Gene Symbol | Kdm3b |
Entrez Gene ID | 277250 |
Full Name | KDM3B lysine (K)-specific demethylase 3B |
Synonyms | 5830462I21Rik,JHDM2B,Jmjd1b,mKIAA1082 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001081256.1 | NP_001074725.1 | lysine-specific demethylase 3B |
Pan troglodytes (chimpanzee) | KDM3B | XP_517956.3 |
Mus musculus (house mouse) | Kdm3b | NP_001074725.1 |
Danio rerio (zebrafish) | wu:fe01c10 | XP_005173195.1 |
KDM3B | XP_002804573.1 | |
Gallus gallus (chicken) | KDM3B | XP_004945121.1 |
Xenopus tropicalis (tropical clawed frog) | kdm3b | XP_002936894.1 |
Bos taurus (cattle) | KDM3B | XP_003586349.1 |
Homo sapiens (human) | KDM3B | NP_057688.2 |
Canis lupus familiaris (dog) | KDM3B | XP_531921.3 |
Rattus norvegicus (Norway rat) | Kdm3b | XP_006254677.1 |
The histone H3K9 demethylase Kdm3b is required for somatic growth and female reproductive function.
Liu Z, Chen X, Zhou S, Liao L, Jiang R, Xu J
International journal of biological sciences11(5)494-507(2015)
Knockout of the Histone Demethylase Kdm3b Decreases Spermatogenesis and Impairs Male Sexual Behaviors.
Liu Z, Oyola MG, Zhou S, Chen X, Liao L, Tien JC, Mani SK, Xu J
International journal of biological sciences11(12)1447-57(2015)
Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo.
Burton A, Muller J, Tu S, Padilla-Longoria P, Guccione E, Torres-Padilla ME
Cell reports5(3)687-701(2013 Nov)
Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND, Robson P
Developmental cell18(4)675-85(2010 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These results demonstrate that Kdm3b-mediated H3K9 demethylation plays essential roles in maintenance of the circulating IGF-1, postnatal somatic growth, circulating 17beta-estradiol, and female reproductive function.
Title: The histone H3K9 demethylase Kdm3b is required for somatic growth and female reproductive function.
findings indicate that Kdm3b is required for normal spermatogenesis and sexual behaviors in male mice
Title: Knockout of the Histone Demethylase Kdm3b Decreases Spermatogenesis and Impairs Male Sexual Behaviors.
The following Kdm3b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kdm3b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu13040 | |
Clone ID Related Accession (Same CDS sequence) | NM_001081256.1 | |
Accession Version | NM_001081256.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5289bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-19 | |
Organism | Mus musculus(house mouse) | |
Product | lysine-specific demethylase 3B | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC114820.4. On Feb 6, 2007 this sequence version replaced XM_619530.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC151084.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCGGACG CGGCGGCCTC CCCGGTGGGC AAGCGGCTGT TGCTTCTGTT CGCGGACCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001074725.1 |
CDS | 124..5412 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001081256.1 |
1 | ATGGCGGACG CGGCGGCCTC CCCGGTGGGC AAGCGGCTGT TGCTTCTGTT CGCGGACCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The histone H3K9 demethylase Kdm3b is required for somatic growth and female reproductive function. |
Knockout of the Histone Demethylase Kdm3b Decreases Spermatogenesis and Impairs Male Sexual Behaviors. |
Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo. |
Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. |