Gene Symbol | Foxo6 |
Entrez Gene ID | 329934 |
Full Name | forkhead box O6 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Foxo6 cDNA ORF clone
Gene Symbol | Foxo6 |
Entrez Gene ID | 329934 |
Full Name | forkhead box O6 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_011240558.2 | XP_011238860.1 | forkhead box protein O6 isoform X1 |
NM_194060.1 | NP_918949.1 | forkhead box protein O6 |
XM_011240558.3 | XP_011238860.1 | forkhead box protein O6 isoform X1 |
Homo sapiens (human) | FOXO6 | XP_002342143.5 |
Rattus norvegicus (Norway rat) | Foxo6 | XP_001057233.1 |
Danio rerio (zebrafish) | si:ch211-206a7.2 | NP_001128604.1 |
Danio rerio (zebrafish) | LOC101883250 | XP_005157925.1 |
Xenopus tropicalis (tropical clawed frog) | foxo6 | XP_002939401.1 |
Mus musculus (house mouse) | Foxo6 | NP_918949.1 |
Gallus gallus (chicken) | LOC100857767 | XP_004947769.1 |
Danio rerio (zebrafish) | LOC561541 | XP_690041.2 |
Foxo1 is a downstream effector of Isl1 in direct pathway striatal projection neuron development within the embryonic mouse telencephalon.
Waclaw RR, Ehrman LA, Merchan-Sala P, Kohli V, Nardini D, Campbell K
Molecular and cellular neurosciences8044-51(2017 04)
FoxO6 affects Plxna4-mediated neuronal migration during mouse cortical development.
Paap RH, Oosterbroek S, Wagemans CM, von Oerthel L, Schellevis RD, Vastenhouw-van der Linden AJ, Groot Koerkamp MJ, Hoekman MF, Smidt MP
Proceedings of the National Academy of Sciences of the United States of America(2016 Oct)
Forkhead Box O6 (FoxO6) Depletion Attenuates Hepatic Gluconeogenesis and Protects against Fat-induced Glucose Disorder in Mice.
Calabuig-Navarro V, Yamauchi J, Lee S, Zhang T, Liu YZ, Sadlek K, Coudriet GM, Piganelli JD, Jiang CL, Miller R, Lowe M, Harashima H, Dong HH
The Journal of biological chemistry290(25)15581-94(2015 Jun)
FoxO6 integrates insulin signaling with MTP for regulating VLDL production in the liver.
Kim DH, Zhang T, Lee S, Calabuig-Navarro V, Yamauchi J, Piccirillo A, Fan Y, Uppala R, Goetzman E, Dong HH
Endocrinology155(4)1255-67(2014 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
data indicate that FoxO6 depletion protected against diet-induced glucose intolerance and insulin resistance by attenuating hepatic gluconeogenesis and curbing macrophage infiltration in liver and adipose tissues in mice.
Title: Forkhead Box O6 (FoxO6) Depletion Attenuates Hepatic Gluconeogenesis and Protects against Fat-induced Glucose Disorder in Mice.
FoxO6 is an important signaling molecule upstream of MTP for regulating hepatic VLDL-TG production
Title: FoxO6 integrates insulin signaling with MTP for regulating VLDL production in the liver.
Studies indicate that FoxO6 is produced in the liver of both rodents and humans.
Title: FoxO6 in glucose metabolism (FoxO6).
FoxO6 represses the expression of PGC-1alpha via direct binding to an upstream A/T-rich element (AAGATATCAAAACA,-2228-2215) in the PGC-1alpha promoter.
Title: FoxO6 and PGC-1? form a regulatory loop in myogenic cells.
FoxO6 regulates a program of genes involved in synaptic function upon learning in the hippocampus
Title: FoxO6 regulates memory consolidation and synaptic function.
The following Foxo6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Foxo6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu74841 | |
Clone ID Related Accession (Same CDS sequence) | XM_011240558.2 , XM_011240558.3 | |
Accession Version | XM_011240558.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1338bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | forkhead box protein O6 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011240558.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCACAAC AGATTCTCAC CACTGTCCTC TTTCCAGATG TGGAAGTGAC TTGCCTTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011238860.1 |
CDS | 61..1398 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011240558.3 |
1 | ATGTCACAAC AGATTCTCAC CACTGTCCTC TTTCCAGATG TGGAAGTGAC TTGCCTTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu22891 | |
Clone ID Related Accession (Same CDS sequence) | NM_194060.1 | |
Accession Version | NM_194060.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1680bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-25 | |
Organism | Mus musculus(house mouse) | |
Product | forkhead box protein O6 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ571690.1. On Dec 7, 2005 this sequence version replaced XM_906986.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ571690.1, BC086628.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164139 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCTGCGA AGCTGCGAGC GCATCAGGTG GACGTGGACC CGGACTTCGC GCCGCAGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_918949.1 |
CDS | 10..1689 |
Translation |
Target ORF information:
Target ORF information:
|
NM_194060.1 |
1 | ATGGCTGCGA AGCTGCGAGC GCATCAGGTG GACGTGGACC CGGACTTCGC GCCGCAGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu74841 | |
Clone ID Related Accession (Same CDS sequence) | XM_011240558.2 , XM_011240558.3 | |
Accession Version | XM_011240558.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1338bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | forkhead box protein O6 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011240558.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCACAAC AGATTCTCAC CACTGTCCTC TTTCCAGATG TGGAAGTGAC TTGCCTTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011238860.1 |
CDS | 60..1397 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011240558.2 |
1 | ATGTCACAAC AGATTCTCAC CACTGTCCTC TTTCCAGATG TGGAAGTGAC TTGCCTTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Foxo1 is a downstream effector of Isl1 in direct pathway striatal projection neuron development within the embryonic mouse telencephalon. |
FoxO6 affects Plxna4-mediated neuronal migration during mouse cortical development. |
Forkhead Box O6 (FoxO6) Depletion Attenuates Hepatic Gluconeogenesis and Protects against Fat-induced Glucose Disorder in Mice. |
FoxO6 integrates insulin signaling with MTP for regulating VLDL production in the liver. |