Rsl1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Gene Symbol	Rsl1
Entrez Gene ID	380855
Full Name	regulator of sex limited protein 1
Synonyms	rslcan-9
General protein information	Preferred Names regulator of sex limited protein 1 Names regulator of sex limited protein 1 regulator of sex limited protein-Slp 1 regulator of sex-limitation 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 13 Map Location: 13 B3\|13 34.54 cM

mRNA and Protein(s)

mRNA Protein Name

NM_001013769.1 NP_001013791.1 regulator of sex limited protein 1
Pathways from BioSystems

mRNA	Protein	Name
NM_001013769.1	NP_001013791.1	regulator of sex limited protein 1

Homologies

Mus musculus (house mouse)	Zfp456	NP_001001186.3
Mus musculus (house mouse)	Zfp429	NP_001074410.1
Mus musculus (house mouse)	Zfp455	NP_001041669.1
Mus musculus (house mouse)	Rsl1	NP_001013791.1
Rattus norvegicus (Norway rat)	Rsl1	XP_006232164.1

Gene Ontology
Bibliography

Related articles in PubMed

The KRAB zinc finger protein RSL1 modulates sex-biased gene expression in liver and adipose tissue to maintain metabolic homeostasis.
Krebs CJ, Zhang D, Yin L, Robins DM
Molecular and cellular biology34(2)221-32(2014 Jan)

The KRAB zinc finger protein RSL1 regulates sex- and tissue-specific promoter methylation and dynamic hormone-responsive chromatin configuration.
Krebs CJ, Schultz DC, Robins DM
Molecular and cellular biology32(18)3732-42(2012 Sep)

A pair of mouse KRAB zinc finger proteins modulates multiple indicators of female reproduction.
Krebs CJ, Robins DM
Biology of reproduction82(4)662-8(2010 Apr)

Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2.
Krebs CJ, Larkins LK, Khan SM, Robins DM
Genomics85(6)752-61(2005 Jun)

Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.
Krebs CJ, Larkins LK, Price R, Tullis KM, Miller RD, Robins DM
Genes & development17(21)2664-74(2003 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

RSL1 balances metabolism via liver-to-adipose-tissue communication.
Title: The KRAB zinc finger protein RSL1 modulates sex-biased gene expression in liver and adipose tissue to maintain metabolic homeostasis.

experiments demonstrate a surprisingly dynamic interplay between a hormonal activator, STAT5b, and a KRAB-ZFP repressor, RSL1, and provide unique insights into KRAB-ZFP epigenetic mechanisms
Title: The KRAB zinc finger protein RSL1 regulates sex- and tissue-specific promoter methylation and dynamic hormone-responsive chromatin configuration.

Transcriptional repression by RSL in liver modifies female mouse reproduction via targets that likely impact both hormonal and pheromonal cues.
Title: A pair of mouse KRAB zinc finger proteins modulates multiple indicators of female reproduction.

The following Rsl1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rsl1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu11585	NM_001013769.1 Latest version!	Mus musculus regulator of sex limited protein 1 (Rsl1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rsl1 ( NM_001013769.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001013791.1 Mus musculus regulator of sex limited protein 1 (Rsl1), mRNA.

Price & Availability↑

CloneID	OMu11585
Clone ID Related Accession (Same CDS sequence)	NM_001013769.1
Accession Version	NM_001013769.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1458bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-25
Organism	Mus musculus(house mouse)
Product	regulator of sex limited protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BK001622.1. On Jul 30, 2005 this sequence version replaced XM_354760.3. ##Evidence-Data-START## Transcript exon combination :: BK001622.1, BC103788.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGCGGCTAT CTATTCCAGT TGTCTCTGAC AAGAAGGAAA TGTTGTCCTT CTGGGATGTA 
GCCATTGATT TCTCTCCAGA AGAGTGGGAA TGCCTGGAGC CTGCTCAGTG GGACCTGTAC 
AGGGATGTGA TGCTGGAGAA TTTCAGCCAC CTTGTGTTCC TGGGTCTTGC TGTCTCTAAG 
CCATTCCTGG TGACATTTCT GGAGCAAATA CAAGGGCCTT GGGACATGAA GAGACAAGGA 
ACGGCCCCTG TGTACCCAGG AATAATACCC AATGATCCTA ACAATTGCAG CAAACTGACT 
AATTGTAAAT CACTCCTTAT TACACAAAGA AGAAATCATA TAGGGGAGAA ACCCTACAAG 
TGTGGAGAAT GTGGTAAGGC CCTTAGTTCT CATAAAACAC TTTCTATACA TCAGAGACTT 
CACACTGGAG ACAAACCTTA CAAGTGTGAA GAGTGTCATA AGGCCTTCAG TACTCGCTCA 
TCACTTTTTA TACACATGAA AAATCATACT GATGAAAAAA TCTACAAGTG TGAAGACTGT 
GGCAGAACAT TTTACTATCT TTCAATGCTG AAGCAACATC AGAGAATTCA TTCTGGAGAG 
AAACCCTACA AGTGTGAAGA ATGTGGGAAA AGCTTTAGCT TTCCCTCGTT CCTTAAGCAA 
CATCAAAGAC TTCATTGTAG AAAAAATGCC TTCAAGCATG AACAATGTGT CAACAGATTT 
CCCCCTCCTC TACCCCTTCA GGAACATGAG CAAATCCGTA CTGAAGAGAA ACCCTACAAG 
TGTGGAGAAT GTTATAAAAC CTTTCGTTAT CACTCAGCCC TTAGGATACA CAAGGCAGTT 
CATACTGGAG AGAGACCTTA CAAGTGTGAA GAGTGTGGCA AATGTTTTTC CTCATCTTCC 
TGCCTTAAAA AACATCAAAT ACTTCACTCT GAAGACAACC CCTACAAGTG TGAAGAATGT 
TATAAAGCCT TTCGTAATCA CTCAGCCCTT AGGATTCACA AGACAGTTCA TACGGGAGAG 
AGACCTTACA AATGTCAGGA GTGTGGCAAA TGCTATTCCT CACCTTCCTG CCTTAAAAGA 
CATCAAATAC TTCACTCTAA ATACAACCCC TACAAGTGTG AAGAGTGTGG CAAATGTCTT 
TCCTCATCTT CCTGCCTTAA AACACATCAA ACCCTTCACT CTGAAGACAA ACCCTACAAG 
TGTGAAGACT GCTCCAGATG TTTCTGCTCA TCTTCATCTC TTAGGCGACA TCAAAAATTC 
CATTCTGAAG GCAATCCCTA TAAGTGTGAA AAATGTGACA AAAGATTTTC ATGTTCTGCA 
GGTCTTCAGG ACCATCAAAC AATTCATACT GGGGAGAAAC CATATAGGTG TGAAAATTGT 
CACAAAGCCT TTTGTTATCG CTCATCCCTT AGGAAACATA AGACAGTTCA TACCAGAGAG 
AAATCCACAC ACATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001013791.1
CDS	37..1494
Translation	MRLSIPVVSDKKEMLSFWDVAIDFSPEEWECLEPAQWDLYRDVMLENFSHLVFLGLAVSKPFLVTFLEQIQGPWDMKRQGTAPVYPGIIPNDPNNCSKLTNCKSLLITQRRNHIGEKPYKCGECGKALSSHKTLSIHQRLHTGDKPYKCEECHKAFSTRSSLFIHMKNHTDEKIYKCEDCGRTFYYLSMLKQHQRIHSGEKPYKCEECGKSFSFPSFLKQHQRLHCRKNAFKHEQCVNRFPPPLPLQEHEQIRTEEKPYKCGECYKTFRYHSALRIHKAVHTGERPYKCEECGKCFSSSSCLKKHQILHSEDNPYKCEECYKAFRNHSALRIHKTVHTGERPYKCQECGKCYSSPSCLKRHQILHSKYNPYKCEECGKCLSSSSCLKTHQTLHSEDKPYKCEDCSRCFCSSSSLRRHQKFHSEGNPYKCEKCDKRFSCSAGLQDHQTIHTGEKPYRCENCHKAFCYRSSLRKHKTVHTREKSTHM

Target ORF information:

RefSeq Version	NM_001013769.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus regulator of sex limited protein 1 (Rsl1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001013769.1

ORF Insert Sequence:

ATGCGGCTAT CTATTCCAGT TGTCTCTGAC AAGAAGGAAA TGTTGTCCTT CTGGGATGTA 
GCCATTGATT TCTCTCCAGA AGAGTGGGAA TGCCTGGAGC CTGCTCAGTG GGACCTGTAC 
AGGGATGTGA TGCTGGAGAA TTTCAGCCAC CTTGTGTTCC TGGGTCTTGC TGTCTCTAAG 
CCATTCCTGG TGACATTTCT GGAGCAAATA CAAGGGCCTT GGGACATGAA GAGACAAGGA 
ACGGCCCCTG TGTACCCAGG AATAATACCC AATGATCCTA ACAATTGCAG CAAACTGACT 
AATTGTAAAT CACTCCTTAT TACACAAAGA AGAAATCATA TAGGGGAGAA ACCCTACAAG 
TGTGGAGAAT GTGGTAAGGC CCTTAGTTCT CATAAAACAC TTTCTATACA TCAGAGACTT 
CACACTGGAG ACAAACCTTA CAAGTGTGAA GAGTGTCATA AGGCCTTCAG TACTCGCTCA 
TCACTTTTTA TACACATGAA AAATCATACT GATGAAAAAA TCTACAAGTG TGAAGACTGT 
GGCAGAACAT TTTACTATCT TTCAATGCTG AAGCAACATC AGAGAATTCA TTCTGGAGAG 
AAACCCTACA AGTGTGAAGA ATGTGGGAAA AGCTTTAGCT TTCCCTCGTT CCTTAAGCAA 
CATCAAAGAC TTCATTGTAG AAAAAATGCC TTCAAGCATG AACAATGTGT CAACAGATTT 
CCCCCTCCTC TACCCCTTCA GGAACATGAG CAAATCCGTA CTGAAGAGAA ACCCTACAAG 
TGTGGAGAAT GTTATAAAAC CTTTCGTTAT CACTCAGCCC TTAGGATACA CAAGGCAGTT 
CATACTGGAG AGAGACCTTA CAAGTGTGAA GAGTGTGGCA AATGTTTTTC CTCATCTTCC 
TGCCTTAAAA AACATCAAAT ACTTCACTCT GAAGACAACC CCTACAAGTG TGAAGAATGT 
TATAAAGCCT TTCGTAATCA CTCAGCCCTT AGGATTCACA AGACAGTTCA TACGGGAGAG 
AGACCTTACA AATGTCAGGA GTGTGGCAAA TGCTATTCCT CACCTTCCTG CCTTAAAAGA 
CATCAAATAC TTCACTCTAA ATACAACCCC TACAAGTGTG AAGAGTGTGG CAAATGTCTT 
TCCTCATCTT CCTGCCTTAA AACACATCAA ACCCTTCACT CTGAAGACAA ACCCTACAAG 
TGTGAAGACT GCTCCAGATG TTTCTGCTCA TCTTCATCTC TTAGGCGACA TCAAAAATTC 
CATTCTGAAG GCAATCCCTA TAAGTGTGAA AAATGTGACA AAAGATTTTC ATGTTCTGCA 
GGTCTTCAGG ACCATCAAAC AATTCATACT GGGGAGAAAC CATATAGGTG TGAAAATTGT 
CACAAAGCCT TTTGTTATCG CTCATCCCTT AGGAAACATA AGACAGTTCA TACCAGAGAG 
AAATCCACAC ACATGTGA