Gene Symbol | Kpna7 |
Entrez Gene ID | 381686 |
Full Name | karyopherin alpha 7 (importin alpha 8) |
Synonyms | AW146299,Gm1055 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Kpna7 cDNA ORF clone
Gene Symbol | Kpna7 |
Entrez Gene ID | 381686 |
Full Name | karyopherin alpha 7 (importin alpha 8) |
Synonyms | AW146299,Gm1055 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_017320944.1 | XP_017176433.1 | importin subunit alpha-8 isoform X2 |
NM_001347531.1 | NP_001334460.1 | importin subunit alpha-8 isoform 1 |
NM_001013774.2 | NP_001013796.2 | importin subunit alpha-8 isoform 2 |
Mus musculus (house mouse) | Kpna7 | NP_001013796.2 |
Xenopus tropicalis (tropical clawed frog) | kpna7 | NP_001135557.1 |
Canis lupus familiaris (dog) | KPNA7 | XP_005621155.1 |
Bos taurus (cattle) | KPNA7 | NP_001157419.1 |
Gallus gallus (chicken) | KPNA7 | XP_414795.3 |
Homo sapiens (human) | KPNA7 | NP_001139187.1 |
Pan troglodytes (chimpanzee) | KPNA7 | XP_003318657.1 |
KPNA7 | XP_001093937.2 | |
Rattus norvegicus (Norway rat) | Kpna7 | XP_001074637.3 |
Danio rerio (zebrafish) | kpna7 | NP_998235.1 |
H7N9 Influenza A Virus Exhibits Importin-?7-Mediated Replication in the Mammalian Respiratory Tract.
Bertram S, Thiele S, Dreier C, Resa-Infante P, Preu? A, van Riel D, Mok CKP, Schwalm F, Peiris JSM, Klenk HD, Gabriel G
The American journal of pathology187(4)831-840(2017 Apr)
Changing expression and subcellular distribution of karyopherins during murine oogenesis.
Mihalas BP, Western PS, Loveland KL, McLaughlin EA, Holt JE
Reproduction (Cambridge, England)150(6)485-96(2015 Dec)
Importin ?7 is essential for zygotic genome activation and early mouse development.
Rother F, Shmidt T, Popova E, Krivokharchenko A, H?gel S, Vilianovich L, Ridders M, Tenner K, Alenina N, K?hler M, Hartmann E, Bader M
PloS one6(3)e18310(2011 Mar)
Novel importin-alpha family member Kpna7 is required for normal fertility and fecundity in the mouse.
Hu J, Wang F, Yuan Y, Zhu X, Wang Y, Zhang Y, Kou Z, Wang S, Gao S
The Journal of biological chemistry285(43)33113-22(2010 Oct)
Karyopherin alpha7 (KPNA7), a divergent member of the importin alpha family of nuclear import receptors.
Kelley JB, Talley AM, Spencer A, Gioeli D, Paschal BM
BMC cell biology1163(2010 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
a decreased H7N9 influenza A virus polymerase activity when importin-alpha7 was silenced by siRNA, is reported.
Title: H7N9 Influenza A Virus Exhibits Importin-?7-Mediated Replication in the Mammalian Respiratory Tract.
knocking out of Kpna7 induced abnormalities of gene expression (dppa2, dppa4, and piwil2) and epigenetic modifications (down-regulation of histone H3K27me3). Biochemical analysis showed that KPNA7 interacts with KPNB1 (importin-beta1).
Title: Novel importin-alpha family member Kpna7 is required for normal fertility and fecundity in the mouse.
a novel importin alpha family member with distinct subcellular localization and nuclear localization signal binding characteristics
Title: Karyopherin alpha7 (KPNA7), a divergent member of the importin alpha family of nuclear import receptors.
The following Kpna7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kpna7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu11606 | |
Clone ID Related Accession (Same CDS sequence) | XM_017320944.1 , NM_001013774.2 | |
Accession Version | NM_001013774.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1500bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-26 | |
Organism | Mus musculus(house mouse) | |
Product | importin subunit alpha-8 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC113295.5. On Apr 10, 2007 this sequence version replaced NM_001013774.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AY950703.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCTACCT CAAAGGCTCC CAAAGAGAGG CTGAAGAACT ATAAGTACCG AGGCAAAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001013796.2 |
CDS | 234..1733 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001013774.2 |
1 | ATGGCTACCT CAAAGGCTCC CAAAGAGAGG CTGAAGAACT ATAAGTACCG AGGCAAAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu36408 | |
Clone ID Related Accession (Same CDS sequence) | NM_001347531.1 | |
Accession Version | NM_001347531.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1563bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-30 | |
Organism | Mus musculus(house mouse) | |
Product | importin subunit alpha-8 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC113295.5. On Nov 30, 2016 this sequence version replaced XM_017320943.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## CDS exon combination :: FJ717333.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMN00849374 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCTACCT CAAAGGCTCC CAAAGAGAGG CTGAAGAACT ATAAGTACCG AGGCAAAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001334460.1 |
CDS | 24..1586 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001347531.1 |
1 | ATGGCTACCT CAAAGGCTCC CAAAGAGAGG CTGAAGAACT ATAAGTACCG AGGCAAAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu11606 | |
Clone ID Related Accession (Same CDS sequence) | XM_017320944.1 , NM_001013774.2 | |
Accession Version | XM_017320944.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1500bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | importin subunit alpha-8 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTACCT CAAAGGCTCC CAAAGAGAGG CTGAAGAACT ATAAGTACCG AGGCAAAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017176433.1 |
CDS | 125..1624 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017320944.1 |
1 | ATGGCTACCT CAAAGGCTCC CAAAGAGAGG CTGAAGAACT ATAAGTACCG AGGCAAAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
H7N9 Influenza A Virus Exhibits Importin-?7-Mediated Replication in the Mammalian Respiratory Tract. |
Changing expression and subcellular distribution of karyopherins during murine oogenesis. |
Importin ?7 is essential for zygotic genome activation and early mouse development. |
Novel importin-alpha family member Kpna7 is required for normal fertility and fecundity in the mouse. |
Karyopherin alpha7 (KPNA7), a divergent member of the importin alpha family of nuclear import receptors. |