Gene Symbol | Trim72 |
Entrez Gene ID | 434246 |
Full Name | tripartite motif-containing 72 |
Synonyms | BC067209,MG53 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Trim72 cDNA ORF clone
Gene Symbol | Trim72 |
Entrez Gene ID | 434246 |
Full Name | tripartite motif-containing 72 |
Synonyms | BC067209,MG53 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006508002.3 | XP_006508065.1 | tripartite motif-containing protein 72 isoform X1 |
XM_006508003.3 | XP_006508066.1 | tripartite motif-containing protein 72 isoform X2 |
XM_006508002.4 | XP_006508065.1 | tripartite motif-containing protein 72 isoform X1 |
NM_001079932.3 | NP_001073401.1 | tripartite motif-containing protein 72 |
XM_006508003.4 | XP_006508066.1 | tripartite motif-containing protein 72 isoform X2 |
Pan troglodytes (chimpanzee) | TRIM72 | XP_001157628.2 |
TRIM72 | XP_001112866.1 | |
Mus musculus (house mouse) | Trim72 | NP_001073401.1 |
Rattus norvegicus (Norway rat) | Trim72 | NP_001071143.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100498595 | XP_002940825.2 |
Canis lupus familiaris (dog) | TRIM72 | XP_005621293.1 |
Bos taurus (cattle) | TRIM72 | XP_002698119.1 |
Homo sapiens (human) | TRIM72 | NP_001008275.2 |
Xenopus tropicalis (tropical clawed frog) | trim72 | NP_001008188.1 |
Inhibition of Macrophage Complement Receptor CRIg by TRIM72 Polarizes Innate Immunity of the Lung.
Nagre N, Cong X, Terrazas C, Pepper I, Schreiber JM, Fu H, Sill JM, Christman JW, Satoskar AR, Zhao X
American journal of respiratory cell and molecular biology(2017 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
MG53 is an effective biomarker of myocardial injury and dysfunction in murine hearts. However, MG53 is not expressed in human heart and therefore does not hold utility as a clinical biomarker of myocardial injury
Title: Lack of MG53 in human heart precludes utility as a biomarker of myocardial injury or endogenous cardioprotective factor.
TRIM72 directly and indirectly modulates caveolar endocytosis
Title: TRIM72 modulates caveolar endocytosis in repair of lung cells.
MG53 is a facilitator of rapid injury repair, a mediator of cell migration, and a modulator of myofibroblast differentiation during wound healing
Title: Modulation of wound healing and scar formation by MG53 protein-mediated cell membrane repair.
Zn(2+) interacts with MG53 in protection against injury to the cell membrane
Title: Zinc Binding to MG53 Protein Facilitates Repair of Injury to Cell Membranes.
Findings indicate that the manifestation of metabolic syndrome alters MG53 activity by reducing its extracellular expression in the serum and causing it to aggregate around mitochondria within striated muscle cells.
Title: Effect of metabolic syndrome on mitsugumin 53 expression and function.
The following Trim72 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Trim72 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu17729 | |
Clone ID Related Accession (Same CDS sequence) | XM_006508002.3 , XM_006508002.4 , NM_001079932.3 | |
Accession Version | NM_001079932.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1434bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-09 | |
Organism | Mus musculus(house mouse) | |
Product | tripartite motif-containing protein 72 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC124461.3 and AB231474.1. On Jul 30, 2009 this sequence version replaced NM_001079932.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC067209.1, AB231474.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGTCGGCTG CACCCGGCCT TCTGCGTCAG GAACTGTCCT GCCCACTGTG CTTGCAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001073401.1 |
CDS | 107..1540 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001079932.3 |
1 | ATGTCGGCTG CACCCGGCCT TCTGCGTCAG GAACTGTCCT GCCCACTGTG CTTGCAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu17729 | |
Clone ID Related Accession (Same CDS sequence) | XM_006508002.3 , XM_006508002.4 , NM_001079932.3 | |
Accession Version | XM_006508002.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1434bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | tripartite motif-containing protein 72 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006508002.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCGGCTG CACCCGGCCT TCTGCGTCAG GAACTGTCCT GCCCACTGTG CTTGCAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006508065.1 |
CDS | 654..2087 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006508002.3 |
1 | ATGTCGGCTG CACCCGGCCT TCTGCGTCAG GAACTGTCCT GCCCACTGTG CTTGCAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu39756 | |
Clone ID Related Accession (Same CDS sequence) | XM_006508003.3 , XM_006508003.4 | |
Accession Version | XM_006508003.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 789bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | tripartite motif-containing protein 72 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006508003.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCGGCTG CACCCGGCCT TCTGCGTCAG GAACTGTCCT GCCCACTGTG CTTGCAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006508066.1 |
CDS | 649..1437 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006508003.3 |
1 | ATGTCGGCTG CACCCGGCCT TCTGCGTCAG GAACTGTCCT GCCCACTGTG CTTGCAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu17729 | |
Clone ID Related Accession (Same CDS sequence) | XM_006508002.3 , XM_006508002.4 , NM_001079932.3 | |
Accession Version | XM_006508002.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1434bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | tripartite motif-containing protein 72 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006508002.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCGGCTG CACCCGGCCT TCTGCGTCAG GAACTGTCCT GCCCACTGTG CTTGCAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006508065.1 |
CDS | 616..2049 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006508002.4 |
1 | ATGTCGGCTG CACCCGGCCT TCTGCGTCAG GAACTGTCCT GCCCACTGTG CTTGCAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu39756 | |
Clone ID Related Accession (Same CDS sequence) | XM_006508003.3 , XM_006508003.4 | |
Accession Version | XM_006508003.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 789bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | tripartite motif-containing protein 72 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006508003.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCGGCTG CACCCGGCCT TCTGCGTCAG GAACTGTCCT GCCCACTGTG CTTGCAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006508066.1 |
CDS | 609..1397 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006508003.4 |
1 | ATGTCGGCTG CACCCGGCCT TCTGCGTCAG GAACTGTCCT GCCCACTGTG CTTGCAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Inhibition of Macrophage Complement Receptor CRIg by TRIM72 Polarizes Innate Immunity of the Lung. |