Gene Symbol | Fbxl7 |
Entrez Gene ID | 448987 |
Full Name | F-box and leucine-rich repeat protein 7 |
Synonyms | AL023057,D230018M15Rik,FBL7,Fbl6 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Fbxl7 cDNA ORF clone
gRNAs
Gene Symbol | Fbxl7 |
Entrez Gene ID | 448987 |
Full Name | F-box and leucine-rich repeat protein 7 |
Synonyms | AL023057,D230018M15Rik,FBL7,Fbl6 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006520106.3 | XP_006520169.1 | F-box/LRR-repeat protein 7 isoform X1 |
XM_006520106.4 | XP_006520169.1 | F-box/LRR-repeat protein 7 isoform X1 |
NM_176959.3 | NP_795933.2 | F-box/LRR-repeat protein 7 |
FBXL7 | XP_001087468.1 | |
Canis lupus familiaris (dog) | FBXL7 | XP_005619483.1 |
Drosophila melanogaster (fruit fly) | CG4221 | NP_650512.1 |
Pan troglodytes (chimpanzee) | FBXL7 | XP_001148598.1 |
Bos taurus (cattle) | FBXL7 | XP_002696492.2 |
Gallus gallus (chicken) | FBXL7 | XP_004935160.1 |
Danio rerio (zebrafish) | zgc:158346 | NP_001073511.1 |
Homo sapiens (human) | FBXL7 | NP_036436.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP003285 | XP_307793.5 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP012769 | XP_306070.4 |
Mus musculus (house mouse) | Fbxl7 | NP_795933.2 |
Xenopus tropicalis (tropical clawed frog) | fbxl7 | XP_002933169.1 |
Rattus norvegicus (Norway rat) | Fbxl7 | NP_001102015.1 |
The Proapoptotic F-box Protein Fbxl7 Regulates Mitochondrial Function by Mediating the Ubiquitylation and Proteasomal Degradation of Survivin.
Liu Y, Lear T, Iannone O, Shiva S, Corey C, Rajbhandari S, Jerome J, Chen BB, Mallampalli RK
The Journal of biological chemistry290(19)11843-52(2015 May)
Novel E3 ligase component FBXL7 ubiquitinates and degrades Aurora A, causing mitotic arrest.
Coon TA, Glasser JR, Mallampalli RK, Chen BB
Cell cycle (Georgetown, Tex.)11(4)721-9(2012 Feb)
Systematic analysis and nomenclature of mammalian F-box proteins.
Jin J, Cardozo T, Lovering RC, Elledge SJ, Pagano M, Harper JW
Genes & development18(21)2573-80(2004 Nov)
Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Okazaki N, Kikuno R, Ohara R, Inamoto S, Koseki H, Hiraoka S, Saga Y, Nagase T, Ohara O, Koga H
DNA research : an international journal for rapid publication of reports on genes and genomes10(4)167-80(2003 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
the Skp1.Cul1.F-box protein complex subunit Fbxl7 modulates mitochondrial function by controlling the cellular abundance of survivin
Title: The Proapoptotic F-box Protein Fbxl7 Regulates Mitochondrial Function by Mediating the Ubiquitylation and Proteasomal Degradation of Survivin.
FBXL7 specifically interacts with Aurora A during mitosis but not in interphase, suggesting a regulatory role for FBXL7 in controlling Aurora A abundance during mitosis.
Title: Novel E3 ligase component FBXL7 ubiquitinates and degrades Aurora A, causing mitotic arrest.
The following Fbxl7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fbxl7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu50718 | |
Clone ID Related Accession (Same CDS sequence) | XM_006520106.3 , XM_006520106.4 | |
Accession Version | XM_006520106.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1335bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | F-box/LRR-repeat protein 7 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006520106.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCGCACAC TGAGCACGCC CAGCCCAGCC TTGATATGCC CACCGACTTT GCCAGGATTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006520169.1 |
CDS | 573..1907 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGCGCACAC TGAGCACGCC CAGCCCAGCC TTGATATGCC CACCGACTTT GCCAGGATTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu05785 | |
Clone ID Related Accession (Same CDS sequence) | NM_176959.3 | |
Accession Version | NM_176959.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1476bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-25 | |
Organism | Mus musculus(house mouse) | |
Product | F-box/LRR-repeat protein 7 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC091646.1. On or before May 25, 2005 this sequence version replaced XM_619306.1, NM_176959.2. ##Evidence-Data-START## Transcript exon combination :: BC091646.1, AK048688.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135, SAMN01164138 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGGCGCGA ACAATGGCAA ACAGTACGGC AGTGAGGGCA AAGGCAGCTC AAGCGTCTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_795933.2 |
CDS | 516..1991 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGCGCGA ACAATGGCAA ACAGTACGGC AGTGAGGGCA AAGGCAGCTC AAGCGTCTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu50718 | |
Clone ID Related Accession (Same CDS sequence) | XM_006520106.3 , XM_006520106.4 | |
Accession Version | XM_006520106.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1335bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | F-box/LRR-repeat protein 7 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006520106.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCGCACAC TGAGCACGCC CAGCCCAGCC TTGATATGCC CACCGACTTT GCCAGGATTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006520169.1 |
CDS | 547..1881 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCGCACAC TGAGCACGCC CAGCCCAGCC TTGATATGCC CACCGACTTT GCCAGGATTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The Proapoptotic F-box Protein Fbxl7 Regulates Mitochondrial Function by Mediating the Ubiquitylation and Proteasomal Degradation of Survivin. |
Novel E3 ligase component FBXL7 ubiquitinates and degrades Aurora A, causing mitotic arrest. |
Systematic analysis and nomenclature of mammalian F-box proteins. |
Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. |