Gene Symbol | Tmprss2 |
Entrez Gene ID | 50528 |
Full Name | transmembrane protease, serine 2 |
Synonyms | D16Ertd61e |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Tmprss2 cDNA ORF clone
gRNAs
Gene Symbol | Tmprss2 |
Entrez Gene ID | 50528 |
Full Name | transmembrane protease, serine 2 |
Synonyms | D16Ertd61e |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006523064.3 | XP_006523127.1 | transmembrane protease serine 2 isoform X1 |
XM_006523065.2 | XP_006523128.1 | transmembrane protease serine 2 isoform X1 |
XM_006523064.2 | XP_006523127.1 | transmembrane protease serine 2 isoform X1 |
NM_015775.2 | NP_056590.2 | transmembrane protease serine 2 |
Pan troglodytes (chimpanzee) | TMPRSS2 | XP_531467.2 |
Canis lupus familiaris (dog) | TMPRSS2 | XP_005639053.1 |
Mus musculus (house mouse) | Tmprss2 | NP_056590.2 |
Xenopus tropicalis (tropical clawed frog) | LOC101731874 | XP_004912264.1 |
Homo sapiens (human) | TMPRSS2 | NP_001128571.1 |
Danio rerio (zebrafish) | tmprss2 | NP_001008623.1 |
LOC715138 | XP_001107275.2 | |
Bos taurus (cattle) | TMPRSS2 | NP_001075054.1 |
Rattus norvegicus (Norway rat) | Tmprss2 | NP_569108.2 |
Gallus gallus (chicken) | TMPRSS2 | XP_416737.3 |
Caenorhabditis elegans (roundworm) | svh-1 | NP_501379.2 |
The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases.
Earnest JT, Hantak MP, Li K, McCray PB Jr, Perlman S, Gallagher T
PLoS pathogens13(7)e1006546(2017 Jul)
N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer.
Dardenne E, Beltran H, Benelli M, Gayvert K, Berger A, Puca L, Cyrta J, Sboner A, Noorzad Z, MacDonald T, Cheung C, Yuen KS, Gao D, Chen Y, Eilers M, Mosquera JM, Robinson BD, Elemento O, Rubin MA, Demichelis F, Rickman DS
Cancer cell30(4)563-577(2016 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
DPP4:CD9:TTSP as the protein complexes are necessary for early efficient MERS-coronavirus entry.
Title: The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases.
Genetic inhibition of TMPRSS2-ERG junction oncogene in prostate cancer by means of siRNA has strong antineoplastic effect in a mouse model and in vitro.
Title: Antineoplastic Effects of siRNA against TMPRSS2-ERG Junction Oncogene in Prostate Cancer.
The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis
Title: The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis.
These results demonstrate that TMPRSS2 expression is essential for influenza A virus replication in vivo.
Title: The host protease TMPRSS2 plays a major role in in vivo replication of emerging H7N9 and seasonal influenza viruses.
These data demonstrate that TMPRSS2 is a host factor that is essential for pneumotropism and pathogenicity of H7N9 and H1N1 influenza virus in mice.
Title: TMPRSS2 is a host factor that is essential for pneumotropism and pathogenicity of H7N9 influenza A virus in mice.
The following Tmprss2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tmprss2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu20152 | |
Clone ID Related Accession (Same CDS sequence) | XM_006523064.3 , XM_006523065.2 , XM_006523064.2 , NM_015775.2 | |
Accession Version | NM_015775.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-11-25 | |
Organism | Mus musculus(house mouse) | |
Product | transmembrane protease serine 2 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC054348.1. On Aug 28, 2003 this sequence version replaced NM_015775.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC054348.1, AK141350.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164134 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCATTGA ACTCAGGGTC ACCTCCAGGA ATCGGACCTT GCTATGAGAA CCACGGGTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_056590.2 |
CDS | 231..1703 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCATTGA ACTCAGGGTC ACCTCCAGGA ATCGGACCTT GCTATGAGAA CCACGGGTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu20152 | |
Clone ID Related Accession (Same CDS sequence) | XM_006523064.3 , XM_006523065.2 , XM_006523064.2 , NM_015775.2 | |
Accession Version | XM_006523064.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | transmembrane protease serine 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000082.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006523064.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCATTGA ACTCAGGGTC ACCTCCAGGA ATCGGACCTT GCTATGAGAA CCACGGGTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006523127.1 |
CDS | 104..1576 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCATTGA ACTCAGGGTC ACCTCCAGGA ATCGGACCTT GCTATGAGAA CCACGGGTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu20152 | |
Clone ID Related Accession (Same CDS sequence) | XM_006523064.3 , XM_006523065.2 , XM_006523064.2 , NM_015775.2 | |
Accession Version | XM_006523065.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | transmembrane protease serine 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000082.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006523065.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCATTGA ACTCAGGGTC ACCTCCAGGA ATCGGACCTT GCTATGAGAA CCACGGGTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006523128.1 |
CDS | 77..1549 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCATTGA ACTCAGGGTC ACCTCCAGGA ATCGGACCTT GCTATGAGAA CCACGGGTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu20152 | |
Clone ID Related Accession (Same CDS sequence) | XM_006523064.3 , XM_006523065.2 , XM_006523064.2 , NM_015775.2 | |
Accession Version | XM_006523064.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-02-08 | |
Organism | Mus musculus(House mouse) | |
Product | transmembrane protease serine 2 isoform X1 | |
Comment |
1 | ATGGCATTGA ACTCAGGGTC ACCTCCAGGA ATCGGACCTT GCTATGAGAA CCACGGGTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006523127.1 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCATTGA ACTCAGGGTC ACCTCCAGGA ATCGGACCTT GCTATGAGAA CCACGGGTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases. |
N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer. |