Gene Symbol | Rasa4 |
Entrez Gene ID | 54153 |
Full Name | RAS p21 protein activator 4 |
Synonyms | AA793972,AW112107,BB079060,CAPRI,GAPL |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Rasa4 cDNA ORF clone
Gene Symbol | Rasa4 |
Entrez Gene ID | 54153 |
Full Name | RAS p21 protein activator 4 |
Synonyms | AA793972,AW112107,BB079060,CAPRI,GAPL |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006504443.3 | XP_006504506.1 | ras GTPase-activating protein 4 isoform X1 |
XM_006504443.2 | XP_006504506.1 | ras GTPase-activating protein 4 isoform X1 |
NM_001039103.3 | NP_001034192.1 | ras GTPase-activating protein 4 isoform 2 |
NM_133914.3 | NP_598675.2 | ras GTPase-activating protein 4 isoform 1 |
XM_030254701.1 | XP_030110561.1 | ras GTPase-activating protein 4 isoform X1 |
XM_030254702.1 | XP_030110562.1 | ras GTPase-activating protein 4 isoform X1 |
Canis lupus familiaris (dog) | RASA4 | XP_546937.4 |
Danio rerio (zebrafish) | rasa4 | NP_001092921.1 |
Rattus norvegicus (Norway rat) | Rasa4 | XP_002727999.1 |
Gallus gallus (chicken) | RASA4 | XP_415761.4 |
Homo sapiens (human) | RASA4 | NP_008920.5 |
Pan troglodytes (chimpanzee) | LOC742087 | XP_003318744.1 |
Bos taurus (cattle) | RASA4 | XP_003587887.2 |
Mus musculus (house mouse) | Rasa4 | NP_598675.2 |
Xenopus tropicalis (tropical clawed frog) | LOC100488193 | XP_002933873.1 |
The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.
Ray JP, Staron MM, Shyer JA, Ho PC, Marshall HD, Gray SM, Laidlaw BJ, Araki K, Ahmed R, Kaech SM, Craft J
Immunity43(4)690-702(2015 Oct)
CD28 inhibits T cell adhesion by recruiting CAPRI to the plasma membrane.
Strazza M, Azoulay-Alfaguter I, Dun B, Baquero-Buitrago J, Mor A
Journal of immunology (Baltimore, Md. : 1950)194(6)2871-7(2015 Mar)
Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities.
Dai Y, Walker SA, de Vet E, Cook S, Welch HC, Lockyer PJ
The Journal of biological chemistry286(22)19905-16(2011 Jun)
Brn3a regulates the transition from neurogenesis to terminal differentiation and represses non-neural gene expression in the trigeminal ganglion.
Lanier J, Dykes IM, Nissen S, Eng SR, Turner EE
Developmental dynamics : an official publication of the American Association of Anatomists238(12)3065-79(2009 Dec)
Identification of an alternatively spliced variant of Ca2+-promoted Ras inactivator as a possible regulator of RANKL shedding.
Hikita A, Kadono Y, Chikuda H, Fukuda A, Wakeyama H, Yasuda H, Nakamura K, Oda H, Miyazaki T, Tanaka S
The Journal of biological chemistry280(50)41700-6(2005 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data show that calcium-promoted Ras inactivator (CAPRI) C2AB domains are required for CD28 antigen inhibition of adhesion.
Title: CD28 inhibits T cell adhesion by recruiting CAPRI to the plasma membrane.
Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities
Title: Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities.
deltaCAPRI regulates RANKL shedding by modulating MMP14 expression through Ras signaling cascades other than the Erk pathway
Title: Identification of an alternatively spliced variant of Ca2+-promoted Ras inactivator as a possible regulator of RANKL shedding.
The following Rasa4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rasa4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu36154 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504443.3 , XM_006504443.2 , XM_030254701.1 , XM_030254702.1 | |
Accession Version | XM_006504443.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1359bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | ras GTPase-activating protein 4 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006504443.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGTCTT TCCTGAAGGT GGCAGGGATG CGCTATCTGC ATGGCATCCT GGGCCCCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006504506.1 |
CDS | 1070..2428 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006504443.2 |
1 | ATGGAGTCTT TCCTGAAGGT GGCAGGGATG CGCTATCTGC ATGGCATCCT GGGCCCCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu36154 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504443.3 , XM_006504443.2 , XM_030254701.1 , XM_030254702.1 | |
Accession Version | XM_006504443.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1359bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | ras GTPase-activating protein 4 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006504443.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGTCTT TCCTGAAGGT GGCAGGGATG CGCTATCTGC ATGGCATCCT GGGCCCCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006504506.1 |
CDS | 1232..2590 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006504443.3 |
1 | ATGGAGTCTT TCCTGAAGGT GGCAGGGATG CGCTATCTGC ATGGCATCCT GGGCCCCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu36154 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504443.3 , XM_006504443.2 , XM_030254701.1 , XM_030254702.1 | |
Accession Version | XM_030254701.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1359bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | ras GTPase-activating protein 4 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGTCTT TCCTGAAGGT GGCAGGGATG CGCTATCTGC ATGGCATCCT GGGCCCCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030110561.1 |
CDS | 1102..2460 |
Translation |
Target ORF information:
Target ORF information:
|
XM_030254701.1 |
1 | ATGGAGTCTT TCCTGAAGGT GGCAGGGATG CGCTATCTGC ATGGCATCCT GGGCCCCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu36154 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504443.3 , XM_006504443.2 , XM_030254701.1 , XM_030254702.1 | |
Accession Version | XM_030254702.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1359bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | ras GTPase-activating protein 4 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGTCTT TCCTGAAGGT GGCAGGGATG CGCTATCTGC ATGGCATCCT GGGCCCCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030110562.1 |
CDS | 849..2207 |
Translation |
Target ORF information:
Target ORF information:
|
XM_030254702.1 |
1 | ATGGAGTCTT TCCTGAAGGT GGCAGGGATG CGCTATCTGC ATGGCATCCT GGGCCCCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu00414 | |
Clone ID Related Accession (Same CDS sequence) | NM_001039103.3 | |
Accession Version | NM_001039103.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2271bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-20 | |
Organism | Mus musculus(house mouse) | |
Product | ras GTPase-activating protein 4 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC087420.4, BY195753.1, AY591339.1 and BC092143.1. On Oct 2, 2013 this sequence version replaced NM_001039103.2. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. It encodes isoform 2, which is shorter than isoform 1. ##Evidence-Data-START## Transcript exon combination :: DQ317932.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849382 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCCAAGC GCAGTTCGCT GTCCATCCGA ATCGTAGAAG GGAAAAATCT GCCCGCCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001034192.1 |
CDS | 198..2468 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001039103.3 |
1 | ATGGCCAAGC GCAGTTCGCT GTCCATCCGA ATCGTAGAAG GGAAAAATCT GCCCGCCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu10352 | |
Clone ID Related Accession (Same CDS sequence) | NM_133914.3 | |
Accession Version | NM_133914.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2409bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-20 | |
Organism | Mus musculus(house mouse) | |
Product | ras GTPase-activating protein 4 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC087420.4, BY195753.1, AY591339.1 and BC092143.1. On Oct 2, 2013 this sequence version replaced NM_133914.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: BC057460.1, AK154335.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCCAAGC GCAGTTCGCT GTCCATCCGA ATCGTAGAAG GGAAAAATCT GCCCGCCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_598675.2 |
CDS | 198..2606 |
Translation |
Target ORF information:
Target ORF information:
|
NM_133914.3 |
1 | ATGGCCAAGC GCAGTTCGCT GTCCATCCGA ATCGTAGAAG GGAAAAATCT GCCCGCCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells. |
CD28 inhibits T cell adhesion by recruiting CAPRI to the plasma membrane. |
Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities. |
Brn3a regulates the transition from neurogenesis to terminal differentiation and represses non-neural gene expression in the trigeminal ganglion. |
Identification of an alternatively spliced variant of Ca2+-promoted Ras inactivator as a possible regulator of RANKL shedding. |