Gene Symbol | Irgm2 |
Entrez Gene ID | 54396 |
Full Name | immunity-related GTPase family M member 2 |
Synonyms | AI481100,GTPI,Ifggd2,Iigp2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Irgm2 cDNA ORF clone
Gene Symbol | Irgm2 |
Entrez Gene ID | 54396 |
Full Name | immunity-related GTPase family M member 2 |
Synonyms | AI481100,GTPI,Ifggd2,Iigp2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_019440.3 | NP_062313.3 | interferon inducible GTPase 2 |
Canis lupus familiaris (dog) | IRGM | XP_538594.3 |
Homo sapiens (human) | IRGM | NP_001139277.1 |
Mus musculus (house mouse) | Irgm2 | NP_062313.3 |
Canis lupus familiaris (dog) | LOC606863 | XP_005626335.1 |
Canis lupus familiaris (dog) | LOC100684769 | XP_003431595.1 |
Pan troglodytes (chimpanzee) | IRGM | NP_001153679.1 |
Rattus norvegicus (Norway rat) | Irgm2 | XP_002727758.1 |
The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation.
Langlais D, Barreiro LB, Gros P
The Journal of experimental medicine213(4)585-603(2016 Apr)
Impact of lactobacilli on orally acquired listeriosis.
Archambaud C, Nahori MA, Soubigou G, B?cavin C, Laval L, Lechat P, Smokvina T, Langella P, Lecuit M, Cossart P
Proceedings of the National Academy of Sciences of the United States of America109(41)16684-9(2012 Oct)
Localisation and mislocalisation of the interferon-inducible immunity-related GTPase, Irgm1 (LRG-47) in mouse cells.
Zhao YO, K?nen-Waisman S, Taylor GA, Martens S, Howard JC
PloS one5(1)e8648(2010 Jan)
Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii.
Hunn JP, Koenen-Waisman S, Papic N, Schroeder N, Pawlowski N, Lange R, Kaiser F, Zerrahn J, Martens S, Howard JC
The EMBO journal27(19)2495-509(2008 Oct)
The p47 GTPases Iigp2 and Irgb10 regulate innate immunity and inflammation to murine Chlamydia psittaci infection.
Miyairi I, Tatireddigari VR, Mahdi OS, Rose LA, Belland RJ, Lu L, Williams RW, Byrne GI
Journal of immunology (Baltimore, Md. : 1950)179(3)1814-24(2007 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
p47 GTPases Irgb10 and Iigp2 act together to confer differential susceptibility against murine chlamydial infection.
Title: The p47 GTPases Iigp2 and Irgb10 regulate innate immunity and inflammation to murine Chlamydia psittaci infection.
The following Irgm2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Irgm2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu10930 | |
Clone ID Related Accession (Same CDS sequence) | NM_019440.3 | |
Accession Version | NM_019440.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1188bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-27 | |
Organism | Mus musculus(house mouse) | |
Product | interferon inducible GTPase 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK142291.1 and AJ007972.1. On Sep 20, 2008 this sequence version replaced NM_019440.2. ##Evidence-Data-START## Transcript exon combination :: AK142291.1, AK165347.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGAAGAGG CAGTTGAGTC ACCTGAGGTT AAAGAATTTG AATACTTCTC CGACGCTGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_062313.3 |
CDS | 216..1403 |
Translation |
Target ORF information:
Target ORF information:
|
NM_019440.3 |
1 | ATGGAAGAGG CAGTTGAGTC ACCTGAGGTT AAAGAATTTG AATACTTCTC CGACGCTGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation. |
Impact of lactobacilli on orally acquired listeriosis. |
Localisation and mislocalisation of the interferon-inducible immunity-related GTPase, Irgm1 (LRG-47) in mouse cells. |
Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii. |
The p47 GTPases Iigp2 and Irgb10 regulate innate immunity and inflammation to murine Chlamydia psittaci infection. |