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Pkp3 cDNA ORF clone, Mus musculus(house mouse)

Summary

Gene Symbol Pkp3
Entrez Gene ID 56460
Full Name plakophilin 3
Synonyms 2310056L12Rik
General protein information
Preferred Names

plakophilin 3

Names

plakophilin-3
Gene Type protein-coding
Organism Mus musculus(house mouse)
Genome

7

7|7 F5

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_001162924.1 NP_001156396.1 plakophilin-3 isoform 2
NM_019762.2 NP_062736.2 plakophilin-3 isoform 1
XM_017322376.1 XP_017177865.1 plakophilin-3 isoform X1

Pathways from BioSystems


Homologies


Bos taurus (cattle) PKP3 NP_001070326.1
Mus musculus (house mouse) Pkp3 NP_062736.2
Danio rerio (zebrafish) LOC100330353 XP_002662884.1
Xenopus tropicalis (tropical clawed frog) pkp3 XP_004913458.1
Danio rerio (zebrafish) pkp3a NP_001038745.1
LOC720779 XP_002808101.1
Canis lupus familiaris (dog) PKP3 XP_005631764.1
Gallus gallus (chicken) PKP3 XP_003641337.1
Homo sapiens (human) PKP3 NP_009114.1
Rattus norvegicus (Norway rat) Pkp3 NP_001099785.1

Gene Ontology


Bibliography

Related articles in PubMed

?E-Catenin Is a Positive Regulator of Pancreatic Islet Cell Lineage Differentiation.
Jimenez-Caliani AJ, Pillich R, Yang W, Diaferia GR, Meda P, Crisa L, Cirulli V
Cell reports20(6)1295-1306(2017 Aug)

p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate.
Richardson R, Mitchell K, Hammond NL, Mollo MR, Kouwenhoven EN, Wyatt ND, Donaldson IJ, Zeef L, Burgis T, Blance R, van Heeringen SJ, Stunnenberg HG, Zhou H, Missero C, Romano RA, Sinha S, Dixon MJ, Dixon J
PLoS genetics13(6)e1006828(2017 Jun)

Antagonistic Regulation of Intercellular Cohesion by Plakophilins 1 and 3.
Keil R, Rietscher K, Hatzfeld M
The Journal of investigative dermatology136(10)2022-2029(2016 Oct)

Hematopoietic plakophilin-3 regulates acute tissue-specific and systemic inflammation in mice.
Sklyarova T, van Hengel J, Van Wonterghem E, Libert C, van Roy F, Vandenbroucke RE
European journal of immunology45(10)2898-910(2015 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

data highlight a novel role for hematopoietic PKP3 in the regulation of both locally and systemically induced immune responses.
Title: Hematopoietic plakophilin-3 regulates acute tissue-specific and systemic inflammation in mice.

PKP3 gene down regulation is associated with bladder cancer invasion.
Title: Up-regulation of plakophilin-2 and Down-regulation of plakophilin-3 are correlated with invasiveness in bladder cancer.

PKP3 plays a critical role in morphogenesis of HFs and shafts and in limiting inflammatory responses in the skin
Title: Plakophilin-3-deficient mice develop hair coat abnormalities and are prone to cutaneous inflammation.

The following Pkp3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pkp3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OMu11541 NM_019762.2
Latest version!		 Mus musculus plakophilin 3 (Pkp3), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $391.30
$559.00
OMu82153 XM_017322376.1
Latest version!		 Mus musculus plakophilin 3 (Pkp3), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 10-12 $391.30
$559.00
OMu08561 NM_001162924.1
Latest version!		 Mus musculus plakophilin 3 (Pkp3), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $391.30
$559.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OMu11541
Clone ID Related Accession (Same CDS sequence) NM_019762.2
Accession Version NM_019762.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 2394bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-09-02
Organism Mus musculus(house mouse)
Product plakophilin-3 isoform 1
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC109272.20, BC139775.1 and BC090668.1. On Jun 30, 2009 this sequence version replaced NM_019762.1. Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF136719.1, BC139775.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
ATGCAGGAAG GTAACTTCCT GCTGTCTGCC CTGCAGCCTG AGACTGGTGT TTGCTCCCTG 
GCTCTGCCTT CGGACCTACA GCTGGATCGC CGGGGTGCGG AGGGACCGGA GGCTGATCGA 
CTTAGAGCTG CCAGAGTCCA GGAGCAAGTC CGAGCCCGCC TCCTGCAGCT GGGCCAGCAG 
TCGCGGCACA ATGGGTCTGC TGAGCTTGAT GGCTCCGCGG AGAGCGCCAG AGGCATGCCC 
AGAGGTCAAT ATCACACTAT GCAGACTGGC TTCAGCTCCC GATCCCAGGG CATGAGTGGA 
GACAAGACCT CGACCTTCCG GCCCATCGCC AAGCCGGCCT ACAGCCCAGC TTCCTGGTCC 
TCCCGCTCAG CCGTGGATCT GACGTGCAGT CGGAGGCTGA GTTCTGCCCA CAATGGGGGC 
AGTGCCTTTG GGGCTGTGGG ATATGGGGGT ACCCAGCCCA CTCCACCTAT GCCCACCCGG 
CCAGTGTCCT TCCATGAGCG AGGTGGGGCA GCCAGCAGAG CTGACTATGA CACATTATCC 
CTGCGCTCAC TGAGGCTGGG GCCAGGGGGC CTGGATGACC GTTACAGCGT GGTATCTGAG 
CAACTGGAGC CTGCAGCCGC CTCTACCTAC AGGGCCTATG CTTACGAGCG CCAGGCTAGC 
TCCGGCTCTA GCCGAGCAGG GGGCCTGGAC TGGCCAGAGG CCACAGAGGG ACCACCCAGC 
AGGACCATCC GTGCACCTGC CATGCGAACC CTGCAAAGAT TTCAGAGCAG CCACCGAAGC 
CGTGGGGGTA CCGGGTCAGT GTCAGGTGCC GGCTTGGAGC CAGTGGCCCG AGCCCCATCT 
GTGCGCAGCC TCAGTCTTAG CCTGGCTGAC TCAGGCCACC TGCCAGATGT ACGCGGGCTG 
GACAGCTACA CGGGCCATCG AACCCTGCAG AGGCTCAGCA GTGGCTTTGA TGACATTGAC 
CTGCCTTCAG CAGTCAAGTA CCTCATGGCC TCAGACCCCA ACCTGCAGGT GCTGGGAGCA 
GCTTACATCC AGCACAGGTG TTACAGTGAT GCCGCCGCCA AGAAGCAGGC TCGCAGCCTT 
CAGGCAGTGC CTAGACTGGT GAAGCTCTTC AACCACGCCA ACCAGGAGGT GCAGCGCCAC 
GCCACAGGTG CCATGCGCAA CCTCATCTAC GACAATGTAG ACAACAAGCT GGCGTTGGTA 
GAGGAGAATG GCATTTTTGA GCTGTTGCGG ACACTTCGAG AGCAGGATGA TGAGCTACGC 
AAAAATGTTA CAGGGATCCT ATGGAACCTG TCCTCCAGTG ACCACCTAAA GGACCGCCTC 
GCCCGGGATA CACTGGAGCA GCTCACAGAT CTGGTGCTGA GCCCCCTGTC AGGGGCAGGT 
GGGCCTCCCC TCATCCAGCA GAATGCCTCA GAGGCAGAGA TCTTCTACAA TGCTACTGGC 
TTCCTCAGGA ACCTCAGCTC AGCCTCCCAG GCCACTCGGC AGAAGATGCG CGAGTGCCAT 
GGGCTAGTGG ATGCTCTGGT CACCTACATC AACCATGCCC TGGACGTTGG CAAGTGTGAG 
GACAAGAGTG TGGAAAATGC TGTGTGTGTG CTGAGGAACC TGTCCTACCG CCTCTACGAC 
GAGATGCCGC CATCAGCCTT GCAGCGGCTT GAAGGCCGGG GCCGCAGGGA CATGGCAGGG 
GCTCCGCCTG GTGAAATGGT AGGCTGCTTC ACACCTCAGA GTCGGCGGCT GCGAGAGCTT 
CCTCTCACAG CTGATGCACT CACCTTTGCC GAAGTATCTA AGGATCCCAA GGGCCTCGAA 
TGGCTGTGGA GCCCCCAGAT TGTGGGGTTG TACAACCGAC TGCTGCAGCG CTGTGAACTA 
AATCGGCATA CAACGGAGGC GGCCGCAGGG GCGCTACAGA ATATCACCGC GGGCGACCGC 
AGGTGGGCAG GTGTGCTGAG CCGCCTGGCC CTGGAACAGG AGCGAATCCT GAACCCCTTG 
CTGGACCGCG TTCGCACCGC TGACCACAAC CAACTGCGCT CACTGACTGG CCTCATCCGA 
AACCTGTCTC GGAATGCCAG GAACAAGGAC GAGATGTCCA CAAAGGTAGT GAGCCACCTG 
ATTGAGAAGC TTCCTGGTAG TGTGGGTGAG AAGTGTCCCC CAGCTGAGGT GCTGGTCAAC 
ATCATAGCCG TGCTCAACAA CCTGGTGGTA GCCAGCCCCA TTGCTGCCCG GGACCTGCTC 
TACTTTGATG GCCTCCGAAA GCTGGTCTTC ATCAAAAAGA AGAGGGATAG CCCCGACAGT 
GAGAAGTCTT CCCGGGCAGC CTCCAGCCTC TTGGCCAACC TCTGGCAGTA CAGCAAGCTC 
CACCGTGACT TCCGGGCGAA AGGCTACCGG AAAGAGGACT TCCTGGGTCC ATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_062736.2
CDS102..2495
Translation

Target ORF information:

RefSeq Version NM_019762.2
Organism Mus musculus(house mouse)
Definition Mus musculus plakophilin 3 (Pkp3), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_019762.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
ATGCAGGAAG GTAACTTCCT GCTGTCTGCC CTGCAGCCTG AGACTGGTGT TTGCTCCCTG 
GCTCTGCCTT CGGACCTACA GCTGGATCGC CGGGGTGCGG AGGGACCGGA GGCTGATCGA 
CTTAGAGCTG CCAGAGTCCA GGAGCAAGTC CGAGCCCGCC TCCTGCAGCT GGGCCAGCAG 
TCGCGGCACA ATGGGTCTGC TGAGCTTGAT GGCTCCGCGG AGAGCGCCAG AGGCATGCCC 
AGAGGTCAAT ATCACACTAT GCAGACTGGC TTCAGCTCCC GATCCCAGGG CATGAGTGGA 
GACAAGACCT CGACCTTCCG GCCCATCGCC AAGCCGGCCT ACAGCCCAGC TTCCTGGTCC 
TCCCGCTCAG CCGTGGATCT GACGTGCAGT CGGAGGCTGA GTTCTGCCCA CAATGGGGGC 
AGTGCCTTTG GGGCTGTGGG ATATGGGGGT ACCCAGCCCA CTCCACCTAT GCCCACCCGG 
CCAGTGTCCT TCCATGAGCG AGGTGGGGCA GCCAGCAGAG CTGACTATGA CACATTATCC 
CTGCGCTCAC TGAGGCTGGG GCCAGGGGGC CTGGATGACC GTTACAGCGT GGTATCTGAG 
CAACTGGAGC CTGCAGCCGC CTCTACCTAC AGGGCCTATG CTTACGAGCG CCAGGCTAGC 
TCCGGCTCTA GCCGAGCAGG GGGCCTGGAC TGGCCAGAGG CCACAGAGGG ACCACCCAGC 
AGGACCATCC GTGCACCTGC CATGCGAACC CTGCAAAGAT TTCAGAGCAG CCACCGAAGC 
CGTGGGGGTA CCGGGTCAGT GTCAGGTGCC GGCTTGGAGC CAGTGGCCCG AGCCCCATCT 
GTGCGCAGCC TCAGTCTTAG CCTGGCTGAC TCAGGCCACC TGCCAGATGT ACGCGGGCTG 
GACAGCTACA CGGGCCATCG AACCCTGCAG AGGCTCAGCA GTGGCTTTGA TGACATTGAC 
CTGCCTTCAG CAGTCAAGTA CCTCATGGCC TCAGACCCCA ACCTGCAGGT GCTGGGAGCA 
GCTTACATCC AGCACAGGTG TTACAGTGAT GCCGCCGCCA AGAAGCAGGC TCGCAGCCTT 
CAGGCAGTGC CTAGACTGGT GAAGCTCTTC AACCACGCCA ACCAGGAGGT GCAGCGCCAC 
GCCACAGGTG CCATGCGCAA CCTCATCTAC GACAATGTAG ACAACAAGCT GGCGTTGGTA 
GAGGAGAATG GCATTTTTGA GCTGTTGCGG ACACTTCGAG AGCAGGATGA TGAGCTACGC 
AAAAATGTTA CAGGGATCCT ATGGAACCTG TCCTCCAGTG ACCACCTAAA GGACCGCCTC 
GCCCGGGATA CACTGGAGCA GCTCACAGAT CTGGTGCTGA GCCCCCTGTC AGGGGCAGGT 
GGGCCTCCCC TCATCCAGCA GAATGCCTCA GAGGCAGAGA TCTTCTACAA TGCTACTGGC 
TTCCTCAGGA ACCTCAGCTC AGCCTCCCAG GCCACTCGGC AGAAGATGCG CGAGTGCCAT 
GGGCTAGTGG ATGCTCTGGT CACCTACATC AACCATGCCC TGGACGTTGG CAAGTGTGAG 
GACAAGAGTG TGGAAAATGC TGTGTGTGTG CTGAGGAACC TGTCCTACCG CCTCTACGAC 
GAGATGCCGC CATCAGCCTT GCAGCGGCTT GAAGGCCGGG GCCGCAGGGA CATGGCAGGG 
GCTCCGCCTG GTGAAATGGT AGGCTGCTTC ACACCTCAGA GTCGGCGGCT GCGAGAGCTT 
CCTCTCACAG CTGATGCACT CACCTTTGCC GAAGTATCTA AGGATCCCAA GGGCCTCGAA 
TGGCTGTGGA GCCCCCAGAT TGTGGGGTTG TACAACCGAC TGCTGCAGCG CTGTGAACTA 
AATCGGCATA CAACGGAGGC GGCCGCAGGG GCGCTACAGA ATATCACCGC GGGCGACCGC 
AGGTGGGCAG GTGTGCTGAG CCGCCTGGCC CTGGAACAGG AGCGAATCCT GAACCCCTTG 
CTGGACCGCG TTCGCACCGC TGACCACAAC CAACTGCGCT CACTGACTGG CCTCATCCGA 
AACCTGTCTC GGAATGCCAG GAACAAGGAC GAGATGTCCA CAAAGGTAGT GAGCCACCTG 
ATTGAGAAGC TTCCTGGTAG TGTGGGTGAG AAGTGTCCCC CAGCTGAGGT GCTGGTCAAC 
ATCATAGCCG TGCTCAACAA CCTGGTGGTA GCCAGCCCCA TTGCTGCCCG GGACCTGCTC 
TACTTTGATG GCCTCCGAAA GCTGGTCTTC ATCAAAAAGA AGAGGGATAG CCCCGACAGT 
GAGAAGTCTT CCCGGGCAGC CTCCAGCCTC TTGGCCAACC TCTGGCAGTA CAGCAAGCTC 
CACCGTGACT TCCGGGCGAA AGGCTACCGG AAAGAGGACT TCCTGGGTCC ATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu82153
Clone ID Related Accession (Same CDS sequence) XM_017322376.1
Accession Version XM_017322376.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 2160bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-07
Organism Mus musculus(house mouse)
Product plakophilin-3 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
ATGCCCAGAG GTCAATATCA CACTATGCAG ACTGGCTTCA GCTCCCGATC CCAGGGCATG 
AGTGGAGACA AGACCTCGAC CTTCCGGCCC ATCGCCAAGC CGGCCTACAG CCCAGCTTCC 
TGGTCCTCCC GCTCAGCCGT GGATCTGACG TGCAGTCGGA GGCTGAGTTC TGCCCACAAT 
GGGGGCAGTG CCTTTGGGGC TGTGGGATAT GGGGGTACCC AGCCCACTCC ACCTATGCCC 
ACCCGGCCAG TGTCCTTCCA TGAGCGAGGT GGGGCAGCCA GCAGAGCTGA CTATGACACA 
TTATCCCTGC GCTCACTGAG GCTGGGGCCA GGGGGCCTGG ATGACCGTTA CAGCGTGGTA 
TCTGAGCAAC TGGAGCCTGC AGCCGCCTCT ACCTACAGGG CCTATGCTTA CGAGCGCCAG 
GCTAGCTCCG GCTCTAGCCG AGCAGGGGGC CTGGACTGGC CAGAGGCCAC AGAGGGACCA 
CCCAGCAGGA CCATCCGTGC ACCTGCCATG CGAACCCTGC AAAGATTTCA GAGCAGCCAC 
CGAAGCCGTG GGGGTACCGG GTCAGTGTCA GGTGCCGGCT TGGAGCCAGT GGCCCGAGCC 
CCATCTGTGC GCAGCCTCAG TCTTAGCCTG GCTGACTCAG GCCACCTGCC AGATGTACGC 
GGGCTGGACA GCTACACGGG CCATCGAACC CTGCAGAGGC TCAGCAGTGG CTTTGATGAC 
ATTGACCTGC CTTCAGCAGT CAAGTACCTC ATGGCCTCAG ACCCCAACCT GCAGGTGCTG 
GGAGCAGCTT ACATCCAGCA CAGGTGTTAC AGTGATGCCG CCGCCAAGAA GCAGGCTCGC 
AGCCTTCAGG CAGTGCCTAG ACTGGTGAAG CTCTTCAACC ACGCCAACCA GGAGGTGCAG 
CGCCACGCCA CAGGTGCCAT GCGCAACCTC ATCTACGACA ATGTAGACAA CAAGCTGGCG 
TTGGTAGAGG AGAATGGCAT TTTTGAGCTG TTGCGGACAC TTCGAGAGCA GGATGATGAG 
CTACGCAAAA ATGTTACAGG GATCCTATGG AACCTGTCCT CCAGTGACCA CCTAAAGGAC 
CGCCTCGCCC GGGATACACT GGAGCAGCTC ACAGATCTGG TGCTGAGCCC CCTGTCAGGG 
GCAGGTGGGC CTCCCCTCAT CCAGCAGAAT GCCTCAGAGG CAGAGATCTT CTACAATGCT 
ACTGGCTTCC TCAGGAACCT CAGCTCAGCC TCCCAGGCCA CTCGGCAGAA GATGCGCGAG 
TGCCATGGGC TAGTGGATGC TCTGGTCACC TACATCAACC ATGCCCTGGA CGTTGGCAAG 
TGTGAGGACA AGAGTGTGGA AAATGCTGTG TGTGTGCTGA GGAACCTGTC CTACCGCCTC 
TACGACGAGA TGCCGCCATC AGCCTTGCAG CGGCTTGAAG GCCGGGGCCG CAGGGACATG 
GCAGGGGCTC CGCCTGGTGA AATGGTAGGC TGCTTCACAC CTCAGAGTCG GCGGCTGCGA 
GAGCTTCCTC TCACAGCTGA TGCACTCACC TTTGCCGAAG TATCTAAGGA TCCCAAGGGC 
CTCGAATGGC TGTGGAGCCC CCAGATTGTG GGGTTGTACA ACCGACTGCT GCAGCGCTGT 
GAACTAAATC GGCATACAAC GGAGGCGGCC GCAGGGGCGC TACAGAATAT CACCGCGGGC 
GACCGCAGGT GGGCAGGTGT GCTGAGCCGC CTGGCCCTGG AACAGGAGCG AATCCTGAAC 
CCCTTGCTGG ACCGCGTTCG CACCGCTGAC CACAACCAAC TGCGCTCACT GACTGGCCTC 
ATCCGAAACC TGTCTCGGAA TGCCAGGAAC AAGGACGAGA TGTCCACAAA GGTAGTGAGC 
CACCTGATTG AGAAGCTTCC TGGTAGTGTG GGTGAGAAGT GTCCCCCAGC TGAGGTGCTG 
GTCAACATCA TAGCCGTGCT CAACAACCTG GTGGTAGCCA GCCCCATTGC TGCCCGGGAC 
CTGCTCTACT TTGATGGCCT CCGAAAGCTG GTCTTCATCA AAAAGAAGAG GGATAGCCCC 
GACAGTGAGA AGTCTTCCCG GGCAGCCTCC AGCCTCTTGG CCAACCTCTG GCAGTACAGC 
AAGCTCCACC GTGACTTCCG GGCGAAAGGC TACCGGAAAG AGGACTTCCT GGGTCCATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_017177865.1
CDS260..2419
Translation

Target ORF information:

RefSeq Version XM_017322376.1
Organism Mus musculus(house mouse)
Definition Mus musculus plakophilin 3 (Pkp3), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017322376.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
ATGCCCAGAG GTCAATATCA CACTATGCAG ACTGGCTTCA GCTCCCGATC CCAGGGCATG 
AGTGGAGACA AGACCTCGAC CTTCCGGCCC ATCGCCAAGC CGGCCTACAG CCCAGCTTCC 
TGGTCCTCCC GCTCAGCCGT GGATCTGACG TGCAGTCGGA GGCTGAGTTC TGCCCACAAT 
GGGGGCAGTG CCTTTGGGGC TGTGGGATAT GGGGGTACCC AGCCCACTCC ACCTATGCCC 
ACCCGGCCAG TGTCCTTCCA TGAGCGAGGT GGGGCAGCCA GCAGAGCTGA CTATGACACA 
TTATCCCTGC GCTCACTGAG GCTGGGGCCA GGGGGCCTGG ATGACCGTTA CAGCGTGGTA 
TCTGAGCAAC TGGAGCCTGC AGCCGCCTCT ACCTACAGGG CCTATGCTTA CGAGCGCCAG 
GCTAGCTCCG GCTCTAGCCG AGCAGGGGGC CTGGACTGGC CAGAGGCCAC AGAGGGACCA 
CCCAGCAGGA CCATCCGTGC ACCTGCCATG CGAACCCTGC AAAGATTTCA GAGCAGCCAC 
CGAAGCCGTG GGGGTACCGG GTCAGTGTCA GGTGCCGGCT TGGAGCCAGT GGCCCGAGCC 
CCATCTGTGC GCAGCCTCAG TCTTAGCCTG GCTGACTCAG GCCACCTGCC AGATGTACGC 
GGGCTGGACA GCTACACGGG CCATCGAACC CTGCAGAGGC TCAGCAGTGG CTTTGATGAC 
ATTGACCTGC CTTCAGCAGT CAAGTACCTC ATGGCCTCAG ACCCCAACCT GCAGGTGCTG 
GGAGCAGCTT ACATCCAGCA CAGGTGTTAC AGTGATGCCG CCGCCAAGAA GCAGGCTCGC 
AGCCTTCAGG CAGTGCCTAG ACTGGTGAAG CTCTTCAACC ACGCCAACCA GGAGGTGCAG 
CGCCACGCCA CAGGTGCCAT GCGCAACCTC ATCTACGACA ATGTAGACAA CAAGCTGGCG 
TTGGTAGAGG AGAATGGCAT TTTTGAGCTG TTGCGGACAC TTCGAGAGCA GGATGATGAG 
CTACGCAAAA ATGTTACAGG GATCCTATGG AACCTGTCCT CCAGTGACCA CCTAAAGGAC 
CGCCTCGCCC GGGATACACT GGAGCAGCTC ACAGATCTGG TGCTGAGCCC CCTGTCAGGG 
GCAGGTGGGC CTCCCCTCAT CCAGCAGAAT GCCTCAGAGG CAGAGATCTT CTACAATGCT 
ACTGGCTTCC TCAGGAACCT CAGCTCAGCC TCCCAGGCCA CTCGGCAGAA GATGCGCGAG 
TGCCATGGGC TAGTGGATGC TCTGGTCACC TACATCAACC ATGCCCTGGA CGTTGGCAAG 
TGTGAGGACA AGAGTGTGGA AAATGCTGTG TGTGTGCTGA GGAACCTGTC CTACCGCCTC 
TACGACGAGA TGCCGCCATC AGCCTTGCAG CGGCTTGAAG GCCGGGGCCG CAGGGACATG 
GCAGGGGCTC CGCCTGGTGA AATGGTAGGC TGCTTCACAC CTCAGAGTCG GCGGCTGCGA 
GAGCTTCCTC TCACAGCTGA TGCACTCACC TTTGCCGAAG TATCTAAGGA TCCCAAGGGC 
CTCGAATGGC TGTGGAGCCC CCAGATTGTG GGGTTGTACA ACCGACTGCT GCAGCGCTGT 
GAACTAAATC GGCATACAAC GGAGGCGGCC GCAGGGGCGC TACAGAATAT CACCGCGGGC 
GACCGCAGGT GGGCAGGTGT GCTGAGCCGC CTGGCCCTGG AACAGGAGCG AATCCTGAAC 
CCCTTGCTGG ACCGCGTTCG CACCGCTGAC CACAACCAAC TGCGCTCACT GACTGGCCTC 
ATCCGAAACC TGTCTCGGAA TGCCAGGAAC AAGGACGAGA TGTCCACAAA GGTAGTGAGC 
CACCTGATTG AGAAGCTTCC TGGTAGTGTG GGTGAGAAGT GTCCCCCAGC TGAGGTGCTG 
GTCAACATCA TAGCCGTGCT CAACAACCTG GTGGTAGCCA GCCCCATTGC TGCCCGGGAC 
CTGCTCTACT TTGATGGCCT CCGAAAGCTG GTCTTCATCA AAAAGAAGAG GGATAGCCCC 
GACAGTGAGA AGTCTTCCCG GGCAGCCTCC AGCCTCTTGG CCAACCTCTG GCAGTACAGC 
AAGCTCCACC GTGACTTCCG GGCGAAAGGC TACCGGAAAG AGGACTTCCT GGGTCCATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu08561
Clone ID Related Accession (Same CDS sequence) NM_001162924.1
Accession Version NM_001162924.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 2469bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-09-02
Organism Mus musculus(house mouse)
Product plakophilin-3 isoform 2
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC090668.1. Transcript Variant: This variant (2) uses an alternate exon for its 5' UTR and 5' coding region, compared to variant 1, that results in a protein (isoform 2) with a longer and distinct N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC090668.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849376 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
ATGGAGCCCA CCGCAGGATC TCGGACCCGG ATGGAGCCCA GAAGGAATTG TCCTACAGCA 
GGGACCTCCA GAATGAGCCA GGGAGCCAGT GGGGGCCAGA CCAGCGGCAA GCCTGAGACT 
GGTGTTTGCT CCCTGGCTCT GCCTTCGGAC CTACAGCTGG ATCGCCGGGG TGCGGAGGGA 
CCGGAGGCTG ATCGACTTAG AGCTGCCAGA GTCCAGGAGC AAGTCCGAGC CCGCCTCCTG 
CAGCTGGGCC AGCAGTCGCG GCACAATGGG TCTGCTGAGC TTGATGGCTC CGCGGAGAGC 
GCCAGAGGCA TGCCCAGAGG TCAATATCAC ACTATGCAGA CTGGCTTCAG CTCCCGATCC 
CAGGGCATGA GTGGAGACAA GACCTCGACC TTCCGGCCCA TCGCCAAGCC GGCCTACAGC 
CCAGCTTCCT GGTCCTCCCG CTCAGCCGTG GATCTGACGT GCAGTCGGAG GCTGAGTTCT 
GCCCACAATG GGGGCAGTGC CTTTGGGGCT GTGGGATATG GGGGTACCCA GCCCACTCCA 
CCTATGCCCA CCCGGCCAGT GTCCTTCCAT GAGCGAGGTG GGGCAGCCAG CAGAGCTGAC 
TATGACACAT TATCCCTGCG CTCACTGAGG CTGGGGCCAG GGGGCCTGGA TGACCGTTAC 
AGCGTGGTAT CTGAGCAACT GGAGCCTGCA GCCGCCTCTA CCTACAGGGC CTATGCTTAC 
GAGCGCCAGG CTAGCTCCGG CTCTAGCCGA GCAGGGGGCC TGGACTGGCC AGAGGCCACA 
GAGGGACCAC CCAGCAGGAC CATCCGTGCA CCTGCCATGC GAACCCTGCA AAGATTTCAG 
AGCAGCCACC GAAGCCGTGG GGGTACCGGG TCAGTGTCAG GTGCCGGCTT GGAGCCAGTG 
GCCCGAGCCC CATCTGTGCG CAGCCTCAGT CTTAGCCTGG CTGACTCAGG CCACCTGCCA 
GATGTACGCG GGCTGGACAG CTACACGGGC CATCGAACCC TGCAGAGGCT CAGCAGTGGC 
TTTGATGACA TTGACCTGCC TTCAGCAGTC AAGTACCTCA TGGCCTCAGA CCCCAACCTG 
CAGGTGCTGG GAGCAGCTTA CATCCAGCAC AGGTGTTACA GTGATGCCGC CGCCAAGAAG 
CAGGCTCGCA GCCTTCAGGC AGTGCCTAGA CTGGTGAAGC TCTTCAACCA CGCCAACCAG 
GAGGTGCAGC GCCACGCCAC AGGTGCCATG CGCAACCTCA TCTACGACAA TGTAGACAAC 
AAGCTGGCGT TGGTAGAGGA GAATGGCATT TTTGAGCTGT TGCGGACACT TCGAGAGCAG 
GATGATGAGC TACGCAAAAA TGTTACAGGG ATCCTATGGA ACCTGTCCTC CAGTGACCAC 
CTAAAGGACC GCCTCGCCCG GGATACACTG GAGCAGCTCA CAGATCTGGT GCTGAGCCCC 
CTGTCAGGGG CAGGTGGGCC TCCCCTCATC CAGCAGAATG CCTCAGAGGC AGAGATCTTC 
TACAATGCTA CTGGCTTCCT CAGGAACCTC AGCTCAGCCT CCCAGGCCAC TCGGCAGAAG 
ATGCGCGAGT GCCATGGGCT AGTGGATGCT CTGGTCACCT ACATCAACCA TGCCCTGGAC 
GTTGGCAAGT GTGAGGACAA GAGTGTGGAA AATGCTGTGT GTGTGCTGAG GAACCTGTCC 
TACCGCCTCT ACGACGAGAT GCCGCCATCA GCCTTGCAGC GGCTTGAAGG CCGGGGCCGC 
AGGGACATGG CAGGGGCTCC GCCTGGTGAA ATGGTAGGCT GCTTCACACC TCAGAGTCGG 
CGGCTGCGAG AGCTTCCTCT CACAGCTGAT GCACTCACCT TTGCCGAAGT ATCTAAGGAT 
CCCAAGGGCC TCGAATGGCT GTGGAGCCCC CAGATTGTGG GGTTGTACAA CCGACTGCTG 
CAGCGCTGTG AACTAAATCG GCATACAACG GAGGCGGCCG CAGGGGCGCT ACAGAATATC 
ACCGCGGGCG ACCGCAGGTG GGCAGGTGTG CTGAGCCGCC TGGCCCTGGA ACAGGAGCGA 
ATCCTGAACC CCTTGCTGGA CCGCGTTCGC ACCGCTGACC ACAACCAACT GCGCTCACTG 
ACTGGCCTCA TCCGAAACCT GTCTCGGAAT GCCAGGAACA AGGACGAGAT GTCCACAAAG 
GTAGTGAGCC ACCTGATTGA GAAGCTTCCT GGTAGTGTGG GTGAGAAGTG TCCCCCAGCT 
GAGGTGCTGG TCAACATCAT AGCCGTGCTC AACAACCTGG TGGTAGCCAG CCCCATTGCT 
GCCCGGGACC TGCTCTACTT TGATGGCCTC CGAAAGCTGG TCTTCATCAA AAAGAAGAGG 
GATAGCCCCG ACAGTGAGAA GTCTTCCCGG GCAGCCTCCA GCCTCTTGGC CAACCTCTGG 
CAGTACAGCA AGCTCCACCG TGACTTCCGG GCGAAAGGCT ACCGGAAAGA GGACTTCCTG 
GGTCCATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001156396.1
CDS96..2564
Translation

Target ORF information:

RefSeq Version NM_001162924.1
Organism Mus musculus(house mouse)
Definition Mus musculus plakophilin 3 (Pkp3), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001162924.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
ATGGAGCCCA CCGCAGGATC TCGGACCCGG ATGGAGCCCA GAAGGAATTG TCCTACAGCA 
GGGACCTCCA GAATGAGCCA GGGAGCCAGT GGGGGCCAGA CCAGCGGCAA GCCTGAGACT 
GGTGTTTGCT CCCTGGCTCT GCCTTCGGAC CTACAGCTGG ATCGCCGGGG TGCGGAGGGA 
CCGGAGGCTG ATCGACTTAG AGCTGCCAGA GTCCAGGAGC AAGTCCGAGC CCGCCTCCTG 
CAGCTGGGCC AGCAGTCGCG GCACAATGGG TCTGCTGAGC TTGATGGCTC CGCGGAGAGC 
GCCAGAGGCA TGCCCAGAGG TCAATATCAC ACTATGCAGA CTGGCTTCAG CTCCCGATCC 
CAGGGCATGA GTGGAGACAA GACCTCGACC TTCCGGCCCA TCGCCAAGCC GGCCTACAGC 
CCAGCTTCCT GGTCCTCCCG CTCAGCCGTG GATCTGACGT GCAGTCGGAG GCTGAGTTCT 
GCCCACAATG GGGGCAGTGC CTTTGGGGCT GTGGGATATG GGGGTACCCA GCCCACTCCA 
CCTATGCCCA CCCGGCCAGT GTCCTTCCAT GAGCGAGGTG GGGCAGCCAG CAGAGCTGAC 
TATGACACAT TATCCCTGCG CTCACTGAGG CTGGGGCCAG GGGGCCTGGA TGACCGTTAC 
AGCGTGGTAT CTGAGCAACT GGAGCCTGCA GCCGCCTCTA CCTACAGGGC CTATGCTTAC 
GAGCGCCAGG CTAGCTCCGG CTCTAGCCGA GCAGGGGGCC TGGACTGGCC AGAGGCCACA 
GAGGGACCAC CCAGCAGGAC CATCCGTGCA CCTGCCATGC GAACCCTGCA AAGATTTCAG 
AGCAGCCACC GAAGCCGTGG GGGTACCGGG TCAGTGTCAG GTGCCGGCTT GGAGCCAGTG 
GCCCGAGCCC CATCTGTGCG CAGCCTCAGT CTTAGCCTGG CTGACTCAGG CCACCTGCCA 
GATGTACGCG GGCTGGACAG CTACACGGGC CATCGAACCC TGCAGAGGCT CAGCAGTGGC 
TTTGATGACA TTGACCTGCC TTCAGCAGTC AAGTACCTCA TGGCCTCAGA CCCCAACCTG 
CAGGTGCTGG GAGCAGCTTA CATCCAGCAC AGGTGTTACA GTGATGCCGC CGCCAAGAAG 
CAGGCTCGCA GCCTTCAGGC AGTGCCTAGA CTGGTGAAGC TCTTCAACCA CGCCAACCAG 
GAGGTGCAGC GCCACGCCAC AGGTGCCATG CGCAACCTCA TCTACGACAA TGTAGACAAC 
AAGCTGGCGT TGGTAGAGGA GAATGGCATT TTTGAGCTGT TGCGGACACT TCGAGAGCAG 
GATGATGAGC TACGCAAAAA TGTTACAGGG ATCCTATGGA ACCTGTCCTC CAGTGACCAC 
CTAAAGGACC GCCTCGCCCG GGATACACTG GAGCAGCTCA CAGATCTGGT GCTGAGCCCC 
CTGTCAGGGG CAGGTGGGCC TCCCCTCATC CAGCAGAATG CCTCAGAGGC AGAGATCTTC 
TACAATGCTA CTGGCTTCCT CAGGAACCTC AGCTCAGCCT CCCAGGCCAC TCGGCAGAAG 
ATGCGCGAGT GCCATGGGCT AGTGGATGCT CTGGTCACCT ACATCAACCA TGCCCTGGAC 
GTTGGCAAGT GTGAGGACAA GAGTGTGGAA AATGCTGTGT GTGTGCTGAG GAACCTGTCC 
TACCGCCTCT ACGACGAGAT GCCGCCATCA GCCTTGCAGC GGCTTGAAGG CCGGGGCCGC 
AGGGACATGG CAGGGGCTCC GCCTGGTGAA ATGGTAGGCT GCTTCACACC TCAGAGTCGG 
CGGCTGCGAG AGCTTCCTCT CACAGCTGAT GCACTCACCT TTGCCGAAGT ATCTAAGGAT 
CCCAAGGGCC TCGAATGGCT GTGGAGCCCC CAGATTGTGG GGTTGTACAA CCGACTGCTG 
CAGCGCTGTG AACTAAATCG GCATACAACG GAGGCGGCCG CAGGGGCGCT ACAGAATATC 
ACCGCGGGCG ACCGCAGGTG GGCAGGTGTG CTGAGCCGCC TGGCCCTGGA ACAGGAGCGA 
ATCCTGAACC CCTTGCTGGA CCGCGTTCGC ACCGCTGACC ACAACCAACT GCGCTCACTG 
ACTGGCCTCA TCCGAAACCT GTCTCGGAAT GCCAGGAACA AGGACGAGAT GTCCACAAAG 
GTAGTGAGCC ACCTGATTGA GAAGCTTCCT GGTAGTGTGG GTGAGAAGTG TCCCCCAGCT 
GAGGTGCTGG TCAACATCAT AGCCGTGCTC AACAACCTGG TGGTAGCCAG CCCCATTGCT 
GCCCGGGACC TGCTCTACTT TGATGGCCTC CGAAAGCTGG TCTTCATCAA AAAGAAGAGG 
GATAGCCCCG ACAGTGAGAA GTCTTCCCGG GCAGCCTCCA GCCTCTTGGC CAACCTCTGG 
CAGTACAGCA AGCTCCACCG TGACTTCCGG GCGAAAGGCT ACCGGAAAGA GGACTTCCTG 
GGTCCATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

?E-Catenin Is a Positive Regulator of Pancreatic Islet Cell Lineage Differentiation.
Cell reports20(6)1295-1306(2017 Aug)
Jimenez-Caliani AJ,Pillich R,Yang W,Diaferia GR,Meda P,Crisa L,Cirulli V


book

p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate.
PLoS genetics13(6)e1006828(2017 Jun)
Richardson R,Mitchell K,Hammond NL,Mollo MR,Kouwenhoven EN,Wyatt ND,Donaldson IJ,Zeef L,Burgis T,Blance R,van Heeringen SJ,Stunnenberg HG,Zhou H,Missero C,Romano RA,Sinha S,Dixon MJ,Dixon J


book

Antagonistic Regulation of Intercellular Cohesion by Plakophilins 1 and 3.
The Journal of investigative dermatology136(10)2022-2029(2016 Oct)
Keil R,Rietscher K,Hatzfeld M


book

Hematopoietic plakophilin-3 regulates acute tissue-specific and systemic inflammation in mice.
European journal of immunology45(10)2898-910(2015 Oct)
Sklyarova T,van Hengel J,Van Wonterghem E,Libert C,van Roy F,Vandenbroucke RE