Gene Symbol | Irx6 |
Entrez Gene ID | 64379 |
Full Name | Iroquois homeobox 6 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Irx6 cDNA ORF clone
gRNAs
Gene Symbol | Irx6 |
Entrez Gene ID | 64379 |
Full Name | Iroquois homeobox 6 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001301137.1 | NP_001288066.1 | iroquois-class homeodomain protein IRX-6 isoform 2 |
NM_022428.3 | NP_071873.2 | iroquois-class homeodomain protein IRX-6 isoform 1 |
Mus musculus (house mouse) | Irx6 | NP_071873.2 |
Rattus norvegicus (Norway rat) | Irx6 | NP_001095883.1 |
Danio rerio (zebrafish) | irx6a | NP_001018869.1 |
Homo sapiens (human) | IRX6 | NP_077311.2 |
Bos taurus (cattle) | IRX6 | NP_001179926.1 |
Xenopus tropicalis (tropical clawed frog) | irx6 | XP_002939273.1 |
Pan troglodytes (chimpanzee) | IRX6 | XP_001167355.2 |
IRX6 | XP_001087101.2 | |
Canis lupus familiaris (dog) | IRX6 | XP_005617603.1 |
Onecut1 and Onecut2 redundantly regulate early retinal cell fates during development.
Sapkota D, Chintala H, Wu F, Fliesler SJ, Hu Z, Mu X
Proceedings of the National Academy of Sciences of the United States of America111(39)E4086-95(2014 Sep)
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JLR, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A, Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR
Neuron83(2)309-323(2014 Jul)
Dominant mutations in GRHL3 cause Van der Woude Syndrome and disrupt oral periderm development.
Peyrard-Janvid M, Leslie EJ, Kousa YA, Smith TL, Dunnwald M, Magnusson M, Lentz BA, Unneberg P, Fransson I, Koillinen HK, Rautio J, Pegelow M, Karsten A, Basel-Vanagaite L, Gordon W, Andersen B, Svensson T, Murray JC, Cornell RA, Kere J, Schutte BC
American journal of human genetics94(1)23-32(2014 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Regulation of retinal interneuron subtype identity by the Iroquois homeobox gene Irx6.
Title: Regulation of retinal interneuron subtype identity by the Iroquois homeobox gene Irx6.
The following Irx6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Irx6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu12623 | |
Clone ID Related Accession (Same CDS sequence) | NM_022428.3 | |
Accession Version | NM_022428.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1320bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-27 | |
Organism | Mus musculus(house mouse) | |
Product | iroquois-class homeodomain protein IRX-6 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK035140.1 and AK053729.1. On Jul 23, 2014 this sequence version replaced NM_022428.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK035140.1, AK053729.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164132, SAMN01164136 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCCTTTT CACCTTTTGG ACACCCGTAT GGCAGCACAT CCCAGTTTCT GGTGTCTGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_071873.2 |
CDS | 747..2066 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCCTTTT CACCTTTTGG ACACCCGTAT GGCAGCACAT CCCAGTTTCT GGTGTCTGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu69864 | |
Clone ID Related Accession (Same CDS sequence) | NM_001301137.1 | |
Accession Version | NM_001301137.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1317bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-03 | |
Organism | Mus musculus(house mouse) | |
Product | iroquois-class homeodomain protein IRX-6 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK035140.1, AK053729.1 and BU054800.1. On Jul 23, 2014 this sequence version replaced XM_006531262.1. Transcript Variant: This variant (2) uses an alternate in-frame splice junction at the 5' end of the last exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is 1 aa shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ271055.1, BC130029.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164136 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCCTTTT CACCTTTTGG ACACCCGTAT GGCAGCACAT CCCAGTTTCT GGTGTCTGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001288066.1 |
CDS | 747..2063 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCCTTTT CACCTTTTGG ACACCCGTAT GGCAGCACAT CCCAGTTTCT GGTGTCTGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Onecut1 and Onecut2 redundantly regulate early retinal cell fates during development. |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. |
Dominant mutations in GRHL3 cause Van der Woude Syndrome and disrupt oral periderm development. |