Gene Symbol | Tmem176a |
Entrez Gene ID | 66058 |
Full Name | transmembrane protein 176A |
Synonyms | 0610011I04Rik,AU040201,AU041743,Keg2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Tmem176a cDNA ORF clone
Gene Symbol | Tmem176a |
Entrez Gene ID | 66058 |
Full Name | transmembrane protein 176A |
Synonyms | 0610011I04Rik,AU040201,AU041743,Keg2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001098271.1 | NP_001091741.1 | transmembrane protein 176A |
NM_025326.4 | NP_079602.4 | transmembrane protein 176A |
ROR?t+ cells selectively express redundant cation channels linked to the Golgi apparatus.
Drujont L, Lemoine A, Moreau A, Bienvenu G, Lancien M, Cens T, Guillot F, B?riou G, Bouchet-Delbos L, Fehling HJ, Chiffoleau E, Nicot AB, Charnet P, Martin JC, Josien R, Cuturi MC, Louvet C
Scientific reports623682(2016 Mar)
Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.
Lumayag S, Haldin CE, Corbett NJ, Wahlin KJ, Cowan C, Turturro S, Larsen PE, Kovacs B, Witmer PD, Valle D, Zack DJ, Nicholson DA, Xu S
Proceedings of the National Academy of Sciences of the United States of America110(6)E507-16(2013 Feb)
Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord.
Tamplin OJ, Cox BJ, Rossant J
Developmental biology360(2)415-25(2011 Dec)
Tmem176B and Tmem176A are associated with the immature state of dendritic cells.
Condamine T, Le Texier L, Howie D, Lavault A, Hill M, Halary F, Cobbold S, Waldmann H, Cuturi MC, Chiffoleau E
Journal of leukocyte biology88(3)507-15(2010 Sep)
Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development.
Quina LA, Wang S, Ng L, Turner EE
The Journal of neuroscience : the official journal of the Society for Neuroscience29(45)14309-22(2009 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Study characterized Tmem176a and b expression in RORgamma t+ lymphocytes at transcriptional and protein levels and present evidence that both genes exert a redundant ion channel function related to a colocalisation in close proximity to the Golgi apparatus.
Title: ROR?t+ cells selectively express redundant cation channels linked to the Golgi apparatus.
These data suggest that Tmem176B and Tmem176A associate to form multimers and restrain dendritic cell maturation.
Title: Tmem176B and Tmem176A are associated with the immature state of dendritic cells.
The following Tmem176a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tmem176a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu00285 | |
Clone ID Related Accession (Same CDS sequence) | NM_001098271.1 , NM_025326.4 | |
Accession Version | NM_001098271.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 735bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-16 | |
Organism | Mus musculus(house mouse) | |
Product | transmembrane protein 176A | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY352519.1 and AK002546.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: DV048490.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCCACAG ACATGGAGAC TGCAGTCGTC GGCAAGGTGG ACCCTGAGGC TCCACAACCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001091741.1 |
CDS | 59..793 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001098271.1 |
1 | ATGTCCACAG ACATGGAGAC TGCAGTCGTC GGCAAGGTGG ACCCTGAGGC TCCACAACCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu00285 | |
Clone ID Related Accession (Same CDS sequence) | NM_001098271.1 , NM_025326.4 | |
Accession Version | NM_025326.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 735bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-16 | |
Organism | Mus musculus(house mouse) | |
Product | transmembrane protein 176A | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY018646.1 and AK002546.1. On May 25, 2007 this sequence version replaced NM_025326.3. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: AK002546.1, AK004315.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCCACAG ACATGGAGAC TGCAGTCGTC GGCAAGGTGG ACCCTGAGGC TCCACAACCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_079602.4 |
CDS | 111..845 |
Translation |
Target ORF information:
Target ORF information:
|
NM_025326.4 |
1 | ATGTCCACAG ACATGGAGAC TGCAGTCGTC GGCAAGGTGG ACCCTGAGGC TCCACAACCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
ROR?t+ cells selectively express redundant cation channels linked to the Golgi apparatus. |
Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. |
Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord. |
Tmem176B and Tmem176A are associated with the immature state of dendritic cells. |
Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. |