Gene Symbol | Fam3a |
Entrez Gene ID | 66294 |
Full Name | family with sequence similarity 3, member A |
Synonyms | 1810037C20Rik |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Fam3a cDNA ORF clone
gRNAs
Gene Symbol | Fam3a |
Entrez Gene ID | 66294 |
Full Name | family with sequence similarity 3, member A |
Synonyms | 1810037C20Rik |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_030251475.1 | XP_030107335.1 | protein FAM3A isoform X3 |
XM_011247659.2 | XP_011245961.1 | protein FAM3A isoform X1 |
XM_011247660.2 | XP_011245962.1 | protein FAM3A isoform X2 |
XM_011247660.3 | XP_011245962.1 | protein FAM3A isoform X2 |
NM_001313725.1 | NP_001300654.1 | protein FAM3A precursor |
XM_030251474.1 | XP_030107334.1 | protein FAM3A isoform X1 |
NM_025473.4 | NP_079749.1 | protein FAM3A precursor |
Pan troglodytes (chimpanzee) | FAM3A | XP_001142467.2 |
Mus musculus (house mouse) | Fam3a | NP_079749.1 |
Rattus norvegicus (Norway rat) | Fam3a | NP_001102794.1 |
Homo sapiens (human) | FAM3A | NP_068578.2 |
Bos taurus (cattle) | FAM3A | NP_001069777.1 |
Danio rerio (zebrafish) | fam3a | NP_957094.1 |
FAM3A | XP_001089464.1 | |
Xenopus tropicalis (tropical clawed frog) | fam3a | NP_001007862.1 |
Canis lupus familiaris (dog) | FAM3A | XP_005642093.1 |
FAM3A mediates PPAR?'s protection in liver ischemia-reperfusion injury by activating Akt survival pathway and repressing inflammation and oxidative stress.
Chen Z, Wang J, Yang W, Chen J, Meng Y, Geng B, Cui Q, Yang J
Oncotarget8(30)49882-49896(2017 Jul)
FAM3A enhances adipogenesis of 3T3-L1 preadipocytes via activation of ATP-P2 receptor-Akt signaling pathway.
Chi Y, Li J, Li N, Chen Z, Ma L, Peng W, Pan X, Li M, Yu W, He X, Geng B, Cui Q, Liu Y, Yang J
Oncotarget8(28)45862-45873(2017 Jul)
FAM3A attenuates ER stress-induced mitochondrial dysfunction and apoptosis via CHOP-Wnt pathway.
Song Q, Gou WL, Zhang R
Neurochemistry international9482-9(2016 Mar)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
FAM3A has a protective role against cytotoxicity via regulating the CHOP-Wnt pathway in mitochondria.
Title: FAM3A attenuates ER stress-induced mitochondrial dysfunction and apoptosis via CHOP-Wnt pathway.
FAM3A plays crucial roles in the regulation of glucose and lipid metabolism in the liver, where it activates the PI3K-Akt signaling pathway by way of a Ca(2+) /CaM-dependent mechanism
Title: FAM3A activates PI3K p110?/Akt signaling to ameliorate hepatic gluconeogenesis and lipogenesis.
The following Fam3a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fam3a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu69914 | |
Clone ID Related Accession (Same CDS sequence) | XM_011247659.2 , XM_030251474.1 | |
Accession Version | XM_011247659.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 768bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | protein FAM3A isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000086.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011247659.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGGTTGG CAGGCCCCCT GCGCATCGTG GCCCTAATCA TCATTATGGG TCTCACCTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011245961.1 |
CDS | 233..1000 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGAGGTTGG CAGGCCCCCT GCGCATCGTG GCCCTAATCA TCATTATGGG TCTCACCTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu69915 | |
Clone ID Related Accession (Same CDS sequence) | XM_011247660.2 , XM_011247660.3 | |
Accession Version | XM_011247660.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 645bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | protein FAM3A isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000086.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011247660.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGTCACA TCTGCTATCA TTACTCAGAA CCAAGGGCCA GGAAGTACAA ATGCGGCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011245962.1 |
CDS | 106..750 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGTCACA TCTGCTATCA TTACTCAGAA CCAAGGGCCA GGAAGTACAA ATGCGGCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu14947 | |
Clone ID Related Accession (Same CDS sequence) | NM_001313725.1 , NM_025473.4 | |
Accession Version | NM_001313725.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 693bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-03 | |
Organism | Mus musculus(house mouse) | |
Product | protein FAM3A precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL807376.4 and AK007715.1. On Aug 27, 2015 this sequence version replaced XM_006528236.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants encode the same protein. ##Evidence-Data-START## Transcript exon combination :: BC019752.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164142 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGAGGTTGG CAGGCCCCCT GCGCATCGTG GCCCTAATCA TCATTATGGG TCTCACCTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001300654.1 |
CDS | 237..929 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGAGGTTGG CAGGCCCCCT GCGCATCGTG GCCCTAATCA TCATTATGGG TCTCACCTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu14947 | |
Clone ID Related Accession (Same CDS sequence) | NM_001313725.1 , NM_025473.4 | |
Accession Version | NM_025473.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 693bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-29 | |
Organism | Mus musculus(house mouse) | |
Product | protein FAM3A precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL807376.4 and AK007715.1. On Aug 27, 2015 this sequence version replaced NM_025473.3. Transcript Variant: This variant (1) represents the longer transcript. Both variants encode the same protein. ##Evidence-Data-START## Transcript exon combination :: BC069871.1, AK007715.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164142 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGAGGTTGG CAGGCCCCCT GCGCATCGTG GCCCTAATCA TCATTATGGG TCTCACCTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_079749.1 |
CDS | 588..1280 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGAGGTTGG CAGGCCCCCT GCGCATCGTG GCCCTAATCA TCATTATGGG TCTCACCTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu69914 | |
Clone ID Related Accession (Same CDS sequence) | XM_011247659.2 , XM_030251474.1 | |
Accession Version | XM_030251474.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 768bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | protein FAM3A isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000086.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGGTTGG CAGGCCCCCT GCGCATCGTG GCCCTAATCA TCATTATGGG TCTCACCTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030107334.1 |
CDS | 55..822 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGAGGTTGG CAGGCCCCCT GCGCATCGTG GCCCTAATCA TCATTATGGG TCTCACCTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu69915 | |
Clone ID Related Accession (Same CDS sequence) | XM_011247660.2 , XM_011247660.3 | |
Accession Version | XM_011247660.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 645bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | protein FAM3A isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000086.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011247660.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGTCACA TCTGCTATCA TTACTCAGAA CCAAGGGCCA GGAAGTACAA ATGCGGCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011245962.1 |
CDS | 106..750 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGTCACA TCTGCTATCA TTACTCAGAA CCAAGGGCCA GGAAGTACAA ATGCGGCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu90438 | |
Clone ID Related Accession (Same CDS sequence) | XM_030251475.1 | |
Accession Version | XM_030251475.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | protein FAM3A isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000086.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGTCACA TCTGCTATCA TTACTCAGAA CCAAGGGCCA GGAAGTACAA ATGCGGCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030107335.1 |
CDS | 437..1006 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGTCACA TCTGCTATCA TTACTCAGAA CCAAGGGCCA GGAAGTACAA ATGCGGCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
FAM3A mediates PPAR?'s protection in liver ischemia-reperfusion injury by activating Akt survival pathway and repressing inflammation and oxidative stress. |
FAM3A enhances adipogenesis of 3T3-L1 preadipocytes via activation of ATP-P2 receptor-Akt signaling pathway. |
FAM3A attenuates ER stress-induced mitochondrial dysfunction and apoptosis via CHOP-Wnt pathway. |