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LRRK2 cDNA ORF clone, Mus musculus(House mouse)

Gene Symbol LRRK2
Entrez Gene ID 66725
Full Name leucine-rich repeat kinase 2
Synonyms 4921513O20Rik,9330188B09Rik,AW561911,D630001M17Rik,Gm927,cI-46
General protein information
Preferred Names

leucine-rich repeat kinase 2

Names

leucine-rich repeat serine/threonine-protein kinase 2

Gene Type protein-coding
Organism Mus musculus(House mouse)
Genome

15

15|15 E3


mRNA and Protein(s)

mRNA Protein Name
XM_006521277.3 XP_006521340.1 leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
NM_025730.3 NP_080006.3 leucine-rich repeat serine/threonine-protein kinase 2



Gallus gallus (chicken) LRRK2 XP_003640388.2
Xenopus tropicalis (tropical clawed frog) lrrk2 XP_002932250.2
Macaca mulatta (rhesus monkey) LRRK2 XP_002798616.1
Mus musculus (house mouse) Lrrk2 NP_080006.3
Rattus norvegicus (Norway rat) Lrrk2 NP_001178718.1
Danio rerio (zebrafish) lrrk2 NP_001188385.1
Homo sapiens (human) LRRK2 NP_940980.3
Pan troglodytes (chimpanzee) LRRK2 XP_001168494.1
Canis lupus familiaris (dog) LRRK2 XP_543734.3
Bos taurus (cattle) LRRK2 NP_001193015.1


Related articles in PubMed

Phos-tag analysis of Rab10 phosphorylation by LRRK2: a powerful assay for assessing kinase function and inhibitors.
Ito G, Katsemonova K, Tonelli F, Lis P, Baptista MA, Shpiro N, Duddy G, Wilson S, Ho PW, Ho SL, Reith AD, Alessi DR
The Biochemical journal473(17)2671-85(2016 Sep)

LRRK2 modulates microglial activity through regulation of chemokine (C-X3-C) receptor 1 -mediated signalling pathways.
Ma B, Xu L, Pan X, Sun L, Ding J, Xie C, Koliatsos VE, Cai H
Human molecular genetics25(16)3515-3523(2016 Aug)

Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts.
Guaitoli G, Raimondi F, Gilsbach BK, Gómez-Llorente Y, Deyaert E, Renzi F, Li X, Schaffner A, Jagtap PK, Boldt K, von Zweydorf F, Gotthardt K, Lorimer DD, Yue Z, Burgin A, Janjic N, Sattler M, Versées W, Ueffing M, Ubarretxena-Belandia I, Kortholt A, Gloeckner CJ
Proceedings of the National Academy of Sciences of the United States of America113(30)E4357-66(2016 Jul)

Altered Expression of
Wu B, Xiao K, Zhang Z, Ma L
BioMed research international20167681259(2016)

Long Non-coding RNA HOTAIR Promotes Parkinson's Disease Induced by MPTP Through up-regulating the Expression of LRRK2.
Liu S, Cui B, Dai ZX, Shi PK, Wang ZH, Guo YY
Current neurovascular research13(2)115-20(2016)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

LRRK2 is expressed in enteric neurons and related to alterations of neuronal peptides and IgA.
Title: LRRK2: An Emerging New Molecule in the Enteric Neuronal System That Quantitatively Regulates Neuronal Peptides and IgA in the Gut.

In addition to disease modeling, leucine-rich repeat kinase 2 (LRRK2) konckin (KI) mice represent a valuable resource for pharmacological studies.
Title: LRRK2 mouse models: dissecting the behavior, striatal neurochemistry and neurophysiology of PD pathogenesis.

LRRK2 kinase activity in microglia can contribute to neuroinflammation in Parkinson's disease via phosphorylating p53 at T304 and T377 site
Title: Phosphorylation of p53 by LRRK2 induces microglial tumor necrosis factor α-mediated neurotoxicity.

LRRK2 negatively regulates the clearance of alphaSYN accompanied by down-regulation of the endocytosis pathway; LRRK2 in microglia may function as the offending molecule responsible for neurodegeneration, in terms of down-regulation of alphaSYN clearance.
Title: Leucine-rich repeat kinase 2 (LRRK2) regulates α-synuclein clearance in microglia.

findings reveal a novel function of LRRK2 in regulating EPO expression and imply a potentially novel relationship between PD genes and hematopoiesis.
Title: Altered Expression of

The following LRRK2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LRRK2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OMu21999 NM_025730.3
Latest version!
Mus musculus leucine-rich repeat kinase 2 (Lrrk2), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 24 $1301.30
$1859.00
OMu51513 XM_006521277.3
Latest version!
Mus musculus leucine-rich repeat kinase 2 (Lrrk2), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 30 $1091.30
$1559.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OMu21999
Clone ID Related Accession (Same CDS sequence) NM_025730.3
Accession Version NM_025730.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 7584bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-30
Organism Mus musculus(House mouse)
Product leucine-rich repeat serine/threonine-protein kinase 2
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK052591.1, AC099704.7, AC158752.5, AK034413.1, AK014886.1, AK014938.1, AK050702.1 and BF660966.1. On May 4, 2007 this sequence version replaced NM_025730.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY792512.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849382 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
4981
5041
5101
5161
5221
5281
5341
5401
5461
5521
5581
5641
5701
5761
5821
5881
5941
6001
6061
6121
6181
6241
6301
6361
6421
6481
6541
6601
6661
6721
6781
6841
6901
6961
7021
7081
7141
7201
7261
7321
7381
7441
7501
7561
ATGGCCAGTG GCGCCTGTCA GGGCTGCGAA GAGGAAGAGG AGGAGGAGGC TCTGAAGAAG 
TTGATAGTCA GGCTGAATAA TGTCCAGGAA GGCAAGCAGA TCGAGACGTT GCTTCAGCTC
CTGGAGGACA TGCTGGTGTT CACCTACTCG GACCGCGCCT CCAAGTTATT TGAAGATAAA
AATTTCCACG TGCCTCTGTT GATTGTCCTG GACTCCTACA TGAGAGTTGC CAGTGTACAG
CAGGCGGGGT GGTCACTTCT GTGCAAATTA ATAGAAGTCT GTCCAGGGAC ATTGCAAAGC
TTAATAGGAC CCCAGGATAT TGGAAATGAT TGGGAAGTCC TTGGTATTCA CCGGCTGATT
CTTAAAATGT TAACTGTTCA TCACGCCAAT GTAAACCTGT CAATAGTTGG ACTAAAAGCC
TTGGATCTCC TCCTAGATTC AGGTAAACTC ACCTTGCTGA TACTGGATGA AGAATGTGAT
ATTTTCTTGT TAATTTTTGA TGCCATGCAC AGATATTCAG CCAATGATGA AGTCCAAAAA
CTGGGATGCA AAGCTTTACA CGTGCTTTTT GAGAGAGTTT CCGAGGAACA GCTGACTGAG
TTTGTGGAGA ACAAAGATTA CACGATACTG CTGAGTACGT TCGGCAGCTT CAGAAGGGAC
AAGGAGATTG TGTACCACGT ACTTTGCTGC TTGCATTCCC TGGCGGTTAC ATGCAGCAAT
GTAGAGGTCC TCATGAGTGG GAATGTCCGG TGCTACAATC TTGTGGTGGA GGCCATGAAA
GCCTTCCCCA CCAATGAAAA CATCCAAGAG GTGAGCTGCT CCTTGTTCCA GAAGCTTACA
TTAGGTAACT TTTTCAACAT CCTGGTGTTG AACGAAGTGC ATGTCTTTGT GGTGAAAGCG
GTCCGACAGT ATCCTGAGAA CGCAGCCTTA CAGATCTCTG CACTCAGCTG TTTAGCACTC
CTCACTGAGA CTATTTTCTT AAACCAAGAC TTGGAGGAAA GAAGTGAGAC TCAAGAGCAG
AGCGAAGAGG AAGACAGTGA GAAGCTTTTC TGGCTGGAAC CCTGCTATAA AGCCCTGGTG
CGCCATCGAA AGGACAAACA CGTGCAGGAG GCTGCCTGCT GGGCACTAAA TAACCTCCTT
ATGTACCAGA ACAGTTTGCA TGAGAAGATC GGAGATGAAG ATGGCCAGTT CCCTGCGCAC
AGGGAAGTGA TGCTGTCTAT GCTGATGCAC TCTTCTTCCA AAGATGTCTT CCAAGCAGCT
GCACATGCTC TGTCCACTCT CTTGGAACAA AATGTTAATT TCAGGAAAAT CCTGCTGGCA
AAAGGAGTAT ACCTGAATGT CTTGGAATTG ATGCAGAAGC ATGCCCATGC GCCTGAGGTG
GCAGAGAGTG GCTGCAAGAT GCTGAGTCAC CTGTTTGAAG GAAGTAACCC TTCTCTGGAT
ACAATGGCAG CAGTGGTCCC TAAAATACTA ACAGTGATGA AAGCCCACGG AACGTCTCTG
TCAGTCCAGC TGGAGGCGCT GCGAGCTATC TTGCATTTCG TTGTGCCAGG ACTATTGGAA
GAATCCAGGG AGGACTCTCA ATGCAGACCA AATGTGCTCA GAAAACAGTG TTTCAGGACT
GACATCCACA AGCTGGTTCT AGTCGCTCTG AACAGGTTCA TTGGGAATCC TGGGATTCAG
AAATGTGGAT TGAAAGTAAT CTCTTCTCTC GCGCACCTTC CTGATGCCAC AGAGACATTG
TCCCTGCAAG GAGCAGTTGA CTCAGTCCTC CACACCTTAC AGATGTATCC AGATGACCAA
GAAATTCAGT GTCTGGGCTT ACACCTTATG GGATGCTTGA TGACAAAGAA GAATTTCTGC
ATAGGGACAG GGCACCTCCT GGCAAAAATT CTGGCTTCCA CTTTGCAGCG CTTTAAAGAT
GTTGCTGAGG TGCAGACTAC AGGATTACAG ACAACCCTGT CAATACTTGA GCTGTCAGTA
TCTTTCTCCA AGCTGCTAGT GCACTATTCC TTTGATGTGG TGATATTTCA TCAGATGTCT
TCCAGTGTTG TAGAACAAAA GGATGAGCAG TTCCTCAATC TATGTTGCAA ATGCTTTGCA
AAAGTGGCCG TGGATGATGA GCTGAAAAAC ACCATGCTAG AGAGAGCCTG CGATCAGAAT
AACAGCATCA TGGTTGAATG TTTGCTCCTC TTGGGAGCTG ATGCCAACCA AGTGAAGGGG
GCAACTTCTT TAATCTATCA GGTATGTGAG AAAGAGAGCA GTCCTAAATT GGTGGAACTG
TTGCTTAATG GTGGTTGTCG TGAACAAGAT GTACGGAAGG CCCTGACCGT AAGCATCCAA
AAGGGCGACA GCCAGGTCAT CAGCTTGCTC CTCAGGAAAC TTGCCCTGGA CCTGGCCAAC
AACAGCATTT GCCTTGGAGG ATTTGGCATA GGAAAAATTG ATCCTTCTTG GCTTGGTCCT
TTATTTCCAG ATAAGTCATC CAATTTAAGG AAGCAAACAA ACACAGGATC TGTCCTAGCG
AGGAAAGTGC TCCGGTATCA GATGAGAAAC ACCCTTCAAG AAGGCGTGGC CTCAGGCAGT
GACGGCAAGT TTTCTGAAGA CGCGCTGGCG AAATTTGGAG AATGGACCTT TATTCCCGAC
TCTTCTATGG ACAGTGTGTT TGGCCAGAGC GATGATCTGG ATAGCGAAGG CAGCGAGAGC
TCATTTCTCG TGAAGAGGAA GTCCAACTCA ATTAGTGTAG GGGAAGTTTA CAGAGATCTA
GCTCTGCAGC GCTGCTCACC AAATGCTCAG AGGCATTCCA ATTCGCTGGG TCCTGTTTTT
GACCATGAAG ACTTACTGAG ACGAAAAAGA AAAATACTGT CTTCAGATGA GTCTCTCAGG
TCCTCAAGGC TGCCGTCCCA TATGAGGCAA TCAGATAGCT CTTCTTCCCT GGCTTCTGAG
AGAGAACACA TCACGTCGTT AGACCTATCT GCCAACGAAC TCAAAGATAT TGATGCTCTG
AGCCAGAAGT GTTGCCTCAG TAGCCACCTG GAACATCTCA CCAAACTGGA ACTTCACCAG
AATTCACTCA CGAGCTTCCC ACAGCAGCTG TGTGAGACTC TGAAGTGTTT GATACACTTG
GATTTGCACA GTAACAAATT CACCTCATTT CCCTCTTTCG TGTTGAAAAT GCCACGTATC
ACCAACCTAG ATGCCTCTCG AAATGACATC GGGCCAACAG TAGTTTTAGA CCCTGCGATG
AAGTGTCCAA GCCTCAAACA GTTGAATCTG TCCTATAACC AGCTCTCTTC AATCCCAGAG
AATCTTGCCC AAGTGGTGGA GAAACTTGAG CAGCTCCTAC TGGAAGGAAA TAAAATATCC
GGGATTTGCT CTCCCCTGAG CCTGAAGGAA CTGAAGATTT TAAATCTTAG TAAAAATCAC
ATTCCATCCC TACCTGGAGA TTTTCTTGAG GCTTGTTCAA AAGTCGAGAG TTTCAGTGCT
CGCATGAATT TTCTTGCTGC AATGCCTGCC TTACCTTCTT CCATAACGAG CTTAAAATTG
TCTCAGAACT CTTTCACGTG CATTCCAGAA GCGATTTTCA GTCTTCCGCA CTTGCGGTCC
TTGGATATGA GCCACAACAA CATTGAATGT CTGCCGGGAC CTGCACATTG GAAGTCTCTG
AACTTAAGGG AACTCATTTT TAGCAAGAAT CAGATCAGCA CCTTAGACTT TAGTGAGAAC
CCACACGTGT GGTCAAGAGT AGAGAAACTG CATCTCTCTC ATAATAAACT GAAAGAGATT
CCTCCAGAAA TTGGCTGCCT TGAAAATCTG ACGTCTCTCG ACGTCAGTTA CAACTTGGAA
CTGAGGTCCT TCCCAAATGA AATGGGGAAG TTGAGCAAGA TATGGGATCT TCCCTTGGAC
GGACTGCATC TGAATTTTGA CTTTAAGCAC GTAGGATGCA AGGCCAAAGA CATCATAAGG
TTTCTACAAC AACGTCTGAA AAAGGCTGTA CCCTACAACC GAATGAAGCT CATGATTGTG
GGAAATACGG GGAGCGGTAA GACCACTTTA CTGCAACAAC TCATGAAAAT GAAGAAACCA
GAACTTGGCA TGCAGGGTGC CACAGTCGGC ATAGACGTGC GAGACTGGTC CATCCAAATA
CGGGGCAAAA GGAGAAAGGA CCTGGTTCTA AACGTGTGGG ATTTTGCAGG TCGTGAGGAA
TTCTACAGCA CTCACCCCCA CTTCATGACC CAGAGAGCCC TCTACCTGGC TGTCTATGAT
CTCAGCAAGG GGCAGGCAGA GGTGGACGCC ATGAAGCCCT GGCTCTTCAA TATCAAGGCT
CGTGCCTCTT CTTCCCCGGT GATTCTGGTG GGCACACATT TGGATGTTTC TGATGAGAAG
CAGCGGAAAG CGTGCATAAG CAAAATCACG AAGGAACTCC TAAATAAGCG AGGATTCCCC
ACCATCCGGG ACTACCACTT TGTGAATGCC ACCGAGGAGT CAGATGCGCT GGCAAAGCTT
CGGAAAACCA TCATAAATGA GAGCCTTAAT TTCAAGATCC GAGATCAGCC TGTGGTTGGG
CAGCTAATTC CAGATTGCTA CGTAGAACTG GAGAAAATCA TTTTATCAGA GCGGAAAGCT
GTGCCGACTG AGTTTCCTGT GATTAACCGG AAACACCTGT TACAGCTCGT GAACGAACAT
CAGCTGCAGC TGGATGAGAA CGAGCTCCCA CACGCCGTTC ACTTCCTAAA TGAGTCGGGA
GTTCTTCTGC ATTTTCAAGA CCCTGCCCTG CAGCTAAGTG ACCTGTACTT TGTGGAACCC
AAGTGGCTTT GTAAAGTCAT GGCACAGATC TTGACAGTGA AGGTAGACGG CTGTCTGAAA
CATCCTAAGG GCATCATTTC CCGGAGAGAT GTGGAAAAAT TCCTTTCAAA GAAGAAGCGA
TTCCCGAAGA ACTATATGAT GCAATACTTT AAACTATTAG AAAAATTTCA GATCGCATTG
CCAATAGGGG AAGAATATCT TCTGGTTCCA AGCAGCTTGT CTGACCACAG GCCAGTGATA
GAGCTCCCCC ACTGTGAGAA CTCTGAGATC ATCATCCGGC TGTACGAAAT GCCGTACTTT
CCCATGGGAT TTTGGTCAAG ATTGATTAAC CGATTACTTG AAATCTCACC CTTCATGCTT
TCTGGCAGAG AGAGAGCACT ACGCCCTAAC AGGATGTATT GGCGGCAAGG CATCTACTTG
AATTGGTCTC CAGAAGCATA CTGTCTGGTA GGCTCTGAAG TCTTAGACAA TCGACCTGAG
AGTTTCTTGA AAATCACAGT TCCGTCTTGT AGAAAAGGTT GTATTCTTCT GGGCCGAGTT
GTGGATCATA TTGACTCACT CATGGAAGAA TGGTTTCCCG GGTTACTGGA GATTGACATT
TGTGGGGAAG GAGAAACTCT GTTGAAGAAA TGGGCATTGT ACAGTTTTAA TGATGGTGAA
GAACATCAGA AGATCTTGCT TGATGAGTTG ATGAAGAAGG CTGAAGAAGG AGACCTGTTA
ATAAATCCAG ACCAACCAAG GCTCACTATT CCAATATCCC AGATTGCTCC GGACTTGATC
TTGGCTGACC TGCCTAGAAA TATCATGTTG AACAATGATG AGTTGGAATT TGAGGAAGCA
CCAGAGTTTC TCTTAGGCGA TGGAAGTTTT GGATCCGTTT ATCGAGCTGC CTACGAAGGA
GAGGAAGTGG CTGTGAAGAT TTTTAATAAG CACACATCTC TTAGGCTGTT AAGACAAGAG
TTGGTGGTCC TTTGTCACCT TCACCACCCC AGCCTGATAT CCTTGCTGGC GGCTGGTATT
CGTCCTCGGA TGTTGGTAAT GGAGTTGGCC TCCAAAGGTT CCTTGGATCG CCTGCTGCAG
CAGGACAAAG CCAGCCTCAC CAGAACCCTC CAGCACAGGA TCGCGTTGCA TGTGGCCGAC
GGCCTGAGGT ATCTCCACTC AGCCATGATT ATTTACCGTG ACCTGAAGCC CCACAATGTG
CTGCTTTTTA CCCTGTATCC CAATGCTGCC ATCATTGCGA AGATTGCGGA CTACGGGATC
GCACAGTACT GCTGCAGGAT GGGAATAAAG ACATCAGAGG GCACCCCAGG GTTCCGGGCA
CCTGAAGTTG CCAGGGGGAA TGTCATTTAT AACCAACAGG CCGATGTTTA TTCTTTTGGC
TTACTACTTC ACGATATTTG GACAACTGGG AGTAGGATTA TGGAGGGTTT GAGGTTCCCA
AATGAGTTTG ATGAGTTAGC CATACAAGGG AAGTTGCCAG ATCCAGTTAA AGAATATGGC
TGTGCCCCAT GGCCTATGGT TGAGAAGTTA ATTACAAAGT GTTTGAAAGA AAATCCTCAA
GAAAGACCCA CTTCTGCCCA GGTCTTTGAC ATTTTGAATT CGGCTGAATT AATTTGCCTC
ATGCGACACA TTTTAATACC TAAGAACATC ATTGTTGAAT GCATGGTTGC CACGAATCTC
AATAGCAAGA GTGCGACTCT CTGGTTGGGA TGTGGGAACA CAGAAAAAGG ACAGCTTTCC
TTATTTGACT TAAACACGGA AAGATACAGC TATGAGGAAG TTGCTGATAG TAGAATACTG
TGCTTGGCTT TGGTGCATCT CGCTGCTGAG AAAGAGAGCT GGGTTGTGTG CGGGACACAG
TCTGGGGCTC TCCTGGTCAT CAATGTTGAA GAGGAGACAA AGAGACACAC CCTGGAAAAG
ATGACTGATT CTGTCACTTG TTTGCATTGC AATTCCCTTG CCAAGCAGAG CAAGCAAAGT
AACTTTCTTT TGGTGGGAAC TGCTGATGGT AACTTAATGA TATTTGAAGA TAAAGCCGTT
AAGTGTAAAG GAGCTGCCCC CTTGAAGACA CTACACATAG GCGATGTCAG TACGCCCCTG
ATGTGCCTGA GCGAGTCCCT GAATTCATCT GAAAGACACA TCACATGGGG AGGGTGTGGC
ACAAAGGTCT TCTCCTTTTC CAATGATTTC ACCATTCAGA AACTCATCGA GACAAAAACC
AACCAGCTGT TTTCTTACGC AGCTTTCAGC GATTCTAACA TCATAGCGCT GGCAGTAGAC
ACAGCCCTGT ATATTGCCAA GAAAAACAGC CCTGTCGTAG AGGTGTGGGA CAAGAAAACA
GAAAAGCTCT GTGAATTAAT AGACTGTGTG CACTTCTTAA AGGAGGTGAT GGTAAAACTA
AACAAGGAAT CGAAACATCA GCTGTCCTAC TCTGGGAGGG TGAAGGCCCT CTGCCTGCAG
AAGAACACGG CTCTCTGGAT CGGAACTGGA GGAGGCCACA TCTTACTCCT GGATCTTTCT
ACTCGGCGAG TTATCCGCAC CATTCACAAT TTCTGTGATT CTGTGAGAGC CATGGCCACA
GCACAATTAG GAAGCCTTAA GAATGTCATG CTGGTTTTGG GGTACAAGCG GAAGAGTACA
GAGGGTATCC AAGAACAAAA AGAGATACAA TCTTGTTTGT CTATTTGGGA CCTCAATCTT
CCACACGAGG TGCAAAATTT AGAAAAACAC ATTGAAGTAA GAACAGAATT AGCTGATAAA
ATGAGGAAAA CATCTGTTGA ATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_080006.3
CDS58..7641
Misc Feature(1)10..12
Misc Feature(2)2860..2862
Misc Feature(3)3004..3069
Misc Feature(4)3010..3093
Misc Feature(5)3091..3156
Misc Feature(6)3094..3165
Misc Feature(7)3163..3228
Misc Feature(8)3166..3234
Misc Feature(9)3232..3297
Misc Feature(10)3235..3309
Misc Feature(11)3307..3372
Misc Feature(12)3310..3381
Misc Feature(13)3379..3444
Misc Feature(14)3382..3447
Misc Feature(15)3445..3510
Misc Feature(16)3448..3567
Misc Feature(17)3568..3648
Misc Feature(18)3577..3642
Misc Feature(19)3646..3711
Misc Feature(20)3649..3720
Misc Feature(21)3718..3783
Misc Feature(22)3721..3795
Misc Feature(23)3793..3858
Misc Feature(24)3862..3930
Misc Feature(25)3865..3930
Misc Feature(26)4054..4710
Misc Feature(27)4057..4578
Misc Feature(28)4078..4101
Misc Feature(29)order(4093..4104,4246..4248,4411..4416,4420..4422,4522..4530)
Misc Feature(30)4159..4161
Misc Feature(31)4171..4179
Misc Feature(32)4237..4248
Misc Feature(33)order(4243..4248,4294..4299)
Misc Feature(34)4411..4422
Misc Feature(35)4522..4530
Misc Feature(36)4636..5277
Misc Feature(37)5707..6462
Misc Feature(38)5707..6441
Misc Feature(39)order(5707..5721,5731..5733,5767..5769,5773..5775,5854..5856,5896..5907,5917..5919,5923..5925,6037..6039,6043..6045,6049..6054,6058..6060,6106..6108,6115..6117,6157..6168)
Misc Feature(40)order(5707..5721,5731..5733,5767..5769,5773..5775,5854..5856,5896..5907,5917..5919,6037..6039,6043..6045,6049..6054,6058..6060,6106..6108)
Misc Feature(41)order(5719..5721,5917..5919,5923..5925,6037..6039,6043..6045,6049..6051,6115..6117,6157..6168)
Misc Feature(42)6103..6168
Misc Feature(43)6472..6606
Misc Feature(44)6619..6741
Misc Feature(45)6754..6885
Misc Feature(46)6898..7038
Misc Feature(47)7054..7188
Misc Feature(48)7261..7371
Misc Feature(49)7384..7548
Exon (1)1..214
Exon (2)215..300
Exon (3)301..410
Exon (4)411..499
Exon (5)500..634
Exon (6)635..769
Exon (7)770..901
Exon (8)902..1021
Exon (9)1022..1164
Exon (10)1165..1244
Exon (11)1245..1351
Exon (12)1352..1481
Exon (13)1482..1606
Exon (14)1607..1713
Exon (15)1714..1858
Exon (16)1859..1998
Exon (17)1999..2127
Exon (18)2128..2298
Exon (19)2299..2557
Exon (20)2558..2746
Exon (21)2747..2865
Exon (22)2866..2935
Exon (23)2936..3153
Exon (24)3154..3404
Exon (25)3405..3553
Exon (26)3554..3647
Exon (27)3648..3834
Exon (28)3835..4016
Exon (29)4017..4246
Exon (30)4247..4374
Exon (31)4375..4593
Exon (32)4594..4795
Exon (33)4796..4884
Exon (34)4885..5072
Exon (35)5073..5227
Exon (36)5228..5374
Exon (37)5375..5566
Exon (38)5567..5713
Exon (39)5714..5814
Exon (40)5815..6005
Exon (41)6006..6166
Exon (42)6167..6337
Exon (43)6338..6438
Exon (44)6439..6633
Exon (45)6634..6827
Exon (46)6828..6900
Exon (47)6901..7085
Exon (48)7086..7238
Exon (49)7239..7447
Exon (50)7448..7519
Exon (51)7520..8230
Translation

Target ORF information:

RefSeq Version NM_025730.3
Organism Mus musculus(House mouse)
Definition Mus musculus leucine-rich repeat kinase 2 (Lrrk2), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_025730.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
4981
5041
5101
5161
5221
5281
5341
5401
5461
5521
5581
5641
5701
5761
5821
5881
5941
6001
6061
6121
6181
6241
6301
6361
6421
6481
6541
6601
6661
6721
6781
6841
6901
6961
7021
7081
7141
7201
7261
7321
7381
7441
7501
7561
ATGGCCAGTG GCGCCTGTCA GGGCTGCGAA GAGGAAGAGG AGGAGGAGGC TCTGAAGAAG 
TTGATAGTCA GGCTGAATAA TGTCCAGGAA GGCAAGCAGA TCGAGACGTT GCTTCAGCTC
CTGGAGGACA TGCTGGTGTT CACCTACTCG GACCGCGCCT CCAAGTTATT TGAAGATAAA
AATTTCCACG TGCCTCTGTT GATTGTCCTG GACTCCTACA TGAGAGTTGC CAGTGTACAG
CAGGCGGGGT GGTCACTTCT GTGCAAATTA ATAGAAGTCT GTCCAGGGAC ATTGCAAAGC
TTAATAGGAC CCCAGGATAT TGGAAATGAT TGGGAAGTCC TTGGTATTCA CCGGCTGATT
CTTAAAATGT TAACTGTTCA TCACGCCAAT GTAAACCTGT CAATAGTTGG ACTAAAAGCC
TTGGATCTCC TCCTAGATTC AGGTAAACTC ACCTTGCTGA TACTGGATGA AGAATGTGAT
ATTTTCTTGT TAATTTTTGA TGCCATGCAC AGATATTCAG CCAATGATGA AGTCCAAAAA
CTGGGATGCA AAGCTTTACA CGTGCTTTTT GAGAGAGTTT CCGAGGAACA GCTGACTGAG
TTTGTGGAGA ACAAAGATTA CACGATACTG CTGAGTACGT TCGGCAGCTT CAGAAGGGAC
AAGGAGATTG TGTACCACGT ACTTTGCTGC TTGCATTCCC TGGCGGTTAC ATGCAGCAAT
GTAGAGGTCC TCATGAGTGG GAATGTCCGG TGCTACAATC TTGTGGTGGA GGCCATGAAA
GCCTTCCCCA CCAATGAAAA CATCCAAGAG GTGAGCTGCT CCTTGTTCCA GAAGCTTACA
TTAGGTAACT TTTTCAACAT CCTGGTGTTG AACGAAGTGC ATGTCTTTGT GGTGAAAGCG
GTCCGACAGT ATCCTGAGAA CGCAGCCTTA CAGATCTCTG CACTCAGCTG TTTAGCACTC
CTCACTGAGA CTATTTTCTT AAACCAAGAC TTGGAGGAAA GAAGTGAGAC TCAAGAGCAG
AGCGAAGAGG AAGACAGTGA GAAGCTTTTC TGGCTGGAAC CCTGCTATAA AGCCCTGGTG
CGCCATCGAA AGGACAAACA CGTGCAGGAG GCTGCCTGCT GGGCACTAAA TAACCTCCTT
ATGTACCAGA ACAGTTTGCA TGAGAAGATC GGAGATGAAG ATGGCCAGTT CCCTGCGCAC
AGGGAAGTGA TGCTGTCTAT GCTGATGCAC TCTTCTTCCA AAGATGTCTT CCAAGCAGCT
GCACATGCTC TGTCCACTCT CTTGGAACAA AATGTTAATT TCAGGAAAAT CCTGCTGGCA
AAAGGAGTAT ACCTGAATGT CTTGGAATTG ATGCAGAAGC ATGCCCATGC GCCTGAGGTG
GCAGAGAGTG GCTGCAAGAT GCTGAGTCAC CTGTTTGAAG GAAGTAACCC TTCTCTGGAT
ACAATGGCAG CAGTGGTCCC TAAAATACTA ACAGTGATGA AAGCCCACGG AACGTCTCTG
TCAGTCCAGC TGGAGGCGCT GCGAGCTATC TTGCATTTCG TTGTGCCAGG ACTATTGGAA
GAATCCAGGG AGGACTCTCA ATGCAGACCA AATGTGCTCA GAAAACAGTG TTTCAGGACT
GACATCCACA AGCTGGTTCT AGTCGCTCTG AACAGGTTCA TTGGGAATCC TGGGATTCAG
AAATGTGGAT TGAAAGTAAT CTCTTCTCTC GCGCACCTTC CTGATGCCAC AGAGACATTG
TCCCTGCAAG GAGCAGTTGA CTCAGTCCTC CACACCTTAC AGATGTATCC AGATGACCAA
GAAATTCAGT GTCTGGGCTT ACACCTTATG GGATGCTTGA TGACAAAGAA GAATTTCTGC
ATAGGGACAG GGCACCTCCT GGCAAAAATT CTGGCTTCCA CTTTGCAGCG CTTTAAAGAT
GTTGCTGAGG TGCAGACTAC AGGATTACAG ACAACCCTGT CAATACTTGA GCTGTCAGTA
TCTTTCTCCA AGCTGCTAGT GCACTATTCC TTTGATGTGG TGATATTTCA TCAGATGTCT
TCCAGTGTTG TAGAACAAAA GGATGAGCAG TTCCTCAATC TATGTTGCAA ATGCTTTGCA
AAAGTGGCCG TGGATGATGA GCTGAAAAAC ACCATGCTAG AGAGAGCCTG CGATCAGAAT
AACAGCATCA TGGTTGAATG TTTGCTCCTC TTGGGAGCTG ATGCCAACCA AGTGAAGGGG
GCAACTTCTT TAATCTATCA GGTATGTGAG AAAGAGAGCA GTCCTAAATT GGTGGAACTG
TTGCTTAATG GTGGTTGTCG TGAACAAGAT GTACGGAAGG CCCTGACCGT AAGCATCCAA
AAGGGCGACA GCCAGGTCAT CAGCTTGCTC CTCAGGAAAC TTGCCCTGGA CCTGGCCAAC
AACAGCATTT GCCTTGGAGG ATTTGGCATA GGAAAAATTG ATCCTTCTTG GCTTGGTCCT
TTATTTCCAG ATAAGTCATC CAATTTAAGG AAGCAAACAA ACACAGGATC TGTCCTAGCG
AGGAAAGTGC TCCGGTATCA GATGAGAAAC ACCCTTCAAG AAGGCGTGGC CTCAGGCAGT
GACGGCAAGT TTTCTGAAGA CGCGCTGGCG AAATTTGGAG AATGGACCTT TATTCCCGAC
TCTTCTATGG ACAGTGTGTT TGGCCAGAGC GATGATCTGG ATAGCGAAGG CAGCGAGAGC
TCATTTCTCG TGAAGAGGAA GTCCAACTCA ATTAGTGTAG GGGAAGTTTA CAGAGATCTA
GCTCTGCAGC GCTGCTCACC AAATGCTCAG AGGCATTCCA ATTCGCTGGG TCCTGTTTTT
GACCATGAAG ACTTACTGAG ACGAAAAAGA AAAATACTGT CTTCAGATGA GTCTCTCAGG
TCCTCAAGGC TGCCGTCCCA TATGAGGCAA TCAGATAGCT CTTCTTCCCT GGCTTCTGAG
AGAGAACACA TCACGTCGTT AGACCTATCT GCCAACGAAC TCAAAGATAT TGATGCTCTG
AGCCAGAAGT GTTGCCTCAG TAGCCACCTG GAACATCTCA CCAAACTGGA ACTTCACCAG
AATTCACTCA CGAGCTTCCC ACAGCAGCTG TGTGAGACTC TGAAGTGTTT GATACACTTG
GATTTGCACA GTAACAAATT CACCTCATTT CCCTCTTTCG TGTTGAAAAT GCCACGTATC
ACCAACCTAG ATGCCTCTCG AAATGACATC GGGCCAACAG TAGTTTTAGA CCCTGCGATG
AAGTGTCCAA GCCTCAAACA GTTGAATCTG TCCTATAACC AGCTCTCTTC AATCCCAGAG
AATCTTGCCC AAGTGGTGGA GAAACTTGAG CAGCTCCTAC TGGAAGGAAA TAAAATATCC
GGGATTTGCT CTCCCCTGAG CCTGAAGGAA CTGAAGATTT TAAATCTTAG TAAAAATCAC
ATTCCATCCC TACCTGGAGA TTTTCTTGAG GCTTGTTCAA AAGTCGAGAG TTTCAGTGCT
CGCATGAATT TTCTTGCTGC AATGCCTGCC TTACCTTCTT CCATAACGAG CTTAAAATTG
TCTCAGAACT CTTTCACGTG CATTCCAGAA GCGATTTTCA GTCTTCCGCA CTTGCGGTCC
TTGGATATGA GCCACAACAA CATTGAATGT CTGCCGGGAC CTGCACATTG GAAGTCTCTG
AACTTAAGGG AACTCATTTT TAGCAAGAAT CAGATCAGCA CCTTAGACTT TAGTGAGAAC
CCACACGTGT GGTCAAGAGT AGAGAAACTG CATCTCTCTC ATAATAAACT GAAAGAGATT
CCTCCAGAAA TTGGCTGCCT TGAAAATCTG ACGTCTCTCG ACGTCAGTTA CAACTTGGAA
CTGAGGTCCT TCCCAAATGA AATGGGGAAG TTGAGCAAGA TATGGGATCT TCCCTTGGAC
GGACTGCATC TGAATTTTGA CTTTAAGCAC GTAGGATGCA AGGCCAAAGA CATCATAAGG
TTTCTACAAC AACGTCTGAA AAAGGCTGTA CCCTACAACC GAATGAAGCT CATGATTGTG
GGAAATACGG GGAGCGGTAA GACCACTTTA CTGCAACAAC TCATGAAAAT GAAGAAACCA
GAACTTGGCA TGCAGGGTGC CACAGTCGGC ATAGACGTGC GAGACTGGTC CATCCAAATA
CGGGGCAAAA GGAGAAAGGA CCTGGTTCTA AACGTGTGGG ATTTTGCAGG TCGTGAGGAA
TTCTACAGCA CTCACCCCCA CTTCATGACC CAGAGAGCCC TCTACCTGGC TGTCTATGAT
CTCAGCAAGG GGCAGGCAGA GGTGGACGCC ATGAAGCCCT GGCTCTTCAA TATCAAGGCT
CGTGCCTCTT CTTCCCCGGT GATTCTGGTG GGCACACATT TGGATGTTTC TGATGAGAAG
CAGCGGAAAG CGTGCATAAG CAAAATCACG AAGGAACTCC TAAATAAGCG AGGATTCCCC
ACCATCCGGG ACTACCACTT TGTGAATGCC ACCGAGGAGT CAGATGCGCT GGCAAAGCTT
CGGAAAACCA TCATAAATGA GAGCCTTAAT TTCAAGATCC GAGATCAGCC TGTGGTTGGG
CAGCTAATTC CAGATTGCTA CGTAGAACTG GAGAAAATCA TTTTATCAGA GCGGAAAGCT
GTGCCGACTG AGTTTCCTGT GATTAACCGG AAACACCTGT TACAGCTCGT GAACGAACAT
CAGCTGCAGC TGGATGAGAA CGAGCTCCCA CACGCCGTTC ACTTCCTAAA TGAGTCGGGA
GTTCTTCTGC ATTTTCAAGA CCCTGCCCTG CAGCTAAGTG ACCTGTACTT TGTGGAACCC
AAGTGGCTTT GTAAAGTCAT GGCACAGATC TTGACAGTGA AGGTAGACGG CTGTCTGAAA
CATCCTAAGG GCATCATTTC CCGGAGAGAT GTGGAAAAAT TCCTTTCAAA GAAGAAGCGA
TTCCCGAAGA ACTATATGAT GCAATACTTT AAACTATTAG AAAAATTTCA GATCGCATTG
CCAATAGGGG AAGAATATCT TCTGGTTCCA AGCAGCTTGT CTGACCACAG GCCAGTGATA
GAGCTCCCCC ACTGTGAGAA CTCTGAGATC ATCATCCGGC TGTACGAAAT GCCGTACTTT
CCCATGGGAT TTTGGTCAAG ATTGATTAAC CGATTACTTG AAATCTCACC CTTCATGCTT
TCTGGCAGAG AGAGAGCACT ACGCCCTAAC AGGATGTATT GGCGGCAAGG CATCTACTTG
AATTGGTCTC CAGAAGCATA CTGTCTGGTA GGCTCTGAAG TCTTAGACAA TCGACCTGAG
AGTTTCTTGA AAATCACAGT TCCGTCTTGT AGAAAAGGTT GTATTCTTCT GGGCCGAGTT
GTGGATCATA TTGACTCACT CATGGAAGAA TGGTTTCCCG GGTTACTGGA GATTGACATT
TGTGGGGAAG GAGAAACTCT GTTGAAGAAA TGGGCATTGT ACAGTTTTAA TGATGGTGAA
GAACATCAGA AGATCTTGCT TGATGAGTTG ATGAAGAAGG CTGAAGAAGG AGACCTGTTA
ATAAATCCAG ACCAACCAAG GCTCACTATT CCAATATCCC AGATTGCTCC GGACTTGATC
TTGGCTGACC TGCCTAGAAA TATCATGTTG AACAATGATG AGTTGGAATT TGAGGAAGCA
CCAGAGTTTC TCTTAGGCGA TGGAAGTTTT GGATCCGTTT ATCGAGCTGC CTACGAAGGA
GAGGAAGTGG CTGTGAAGAT TTTTAATAAG CACACATCTC TTAGGCTGTT AAGACAAGAG
TTGGTGGTCC TTTGTCACCT TCACCACCCC AGCCTGATAT CCTTGCTGGC GGCTGGTATT
CGTCCTCGGA TGTTGGTAAT GGAGTTGGCC TCCAAAGGTT CCTTGGATCG CCTGCTGCAG
CAGGACAAAG CCAGCCTCAC CAGAACCCTC CAGCACAGGA TCGCGTTGCA TGTGGCCGAC
GGCCTGAGGT ATCTCCACTC AGCCATGATT ATTTACCGTG ACCTGAAGCC CCACAATGTG
CTGCTTTTTA CCCTGTATCC CAATGCTGCC ATCATTGCGA AGATTGCGGA CTACGGGATC
GCACAGTACT GCTGCAGGAT GGGAATAAAG ACATCAGAGG GCACCCCAGG GTTCCGGGCA
CCTGAAGTTG CCAGGGGGAA TGTCATTTAT AACCAACAGG CCGATGTTTA TTCTTTTGGC
TTACTACTTC ACGATATTTG GACAACTGGG AGTAGGATTA TGGAGGGTTT GAGGTTCCCA
AATGAGTTTG ATGAGTTAGC CATACAAGGG AAGTTGCCAG ATCCAGTTAA AGAATATGGC
TGTGCCCCAT GGCCTATGGT TGAGAAGTTA ATTACAAAGT GTTTGAAAGA AAATCCTCAA
GAAAGACCCA CTTCTGCCCA GGTCTTTGAC ATTTTGAATT CGGCTGAATT AATTTGCCTC
ATGCGACACA TTTTAATACC TAAGAACATC ATTGTTGAAT GCATGGTTGC CACGAATCTC
AATAGCAAGA GTGCGACTCT CTGGTTGGGA TGTGGGAACA CAGAAAAAGG ACAGCTTTCC
TTATTTGACT TAAACACGGA AAGATACAGC TATGAGGAAG TTGCTGATAG TAGAATACTG
TGCTTGGCTT TGGTGCATCT CGCTGCTGAG AAAGAGAGCT GGGTTGTGTG CGGGACACAG
TCTGGGGCTC TCCTGGTCAT CAATGTTGAA GAGGAGACAA AGAGACACAC CCTGGAAAAG
ATGACTGATT CTGTCACTTG TTTGCATTGC AATTCCCTTG CCAAGCAGAG CAAGCAAAGT
AACTTTCTTT TGGTGGGAAC TGCTGATGGT AACTTAATGA TATTTGAAGA TAAAGCCGTT
AAGTGTAAAG GAGCTGCCCC CTTGAAGACA CTACACATAG GCGATGTCAG TACGCCCCTG
ATGTGCCTGA GCGAGTCCCT GAATTCATCT GAAAGACACA TCACATGGGG AGGGTGTGGC
ACAAAGGTCT TCTCCTTTTC CAATGATTTC ACCATTCAGA AACTCATCGA GACAAAAACC
AACCAGCTGT TTTCTTACGC AGCTTTCAGC GATTCTAACA TCATAGCGCT GGCAGTAGAC
ACAGCCCTGT ATATTGCCAA GAAAAACAGC CCTGTCGTAG AGGTGTGGGA CAAGAAAACA
GAAAAGCTCT GTGAATTAAT AGACTGTGTG CACTTCTTAA AGGAGGTGAT GGTAAAACTA
AACAAGGAAT CGAAACATCA GCTGTCCTAC TCTGGGAGGG TGAAGGCCCT CTGCCTGCAG
AAGAACACGG CTCTCTGGAT CGGAACTGGA GGAGGCCACA TCTTACTCCT GGATCTTTCT
ACTCGGCGAG TTATCCGCAC CATTCACAAT TTCTGTGATT CTGTGAGAGC CATGGCCACA
GCACAATTAG GAAGCCTTAA GAATGTCATG CTGGTTTTGG GGTACAAGCG GAAGAGTACA
GAGGGTATCC AAGAACAAAA AGAGATACAA TCTTGTTTGT CTATTTGGGA CCTCAATCTT
CCACACGAGG TGCAAAATTT AGAAAAACAC ATTGAAGTAA GAACAGAATT AGCTGATAAA
ATGAGGAAAA CATCTGTTGA ATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu51513
Clone ID Related Accession (Same CDS sequence) XM_006521277.3
Accession Version XM_006521277.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 6153bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-22
Organism Mus musculus(House mouse)
Product leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006521277.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
4981
5041
5101
5161
5221
5281
5341
5401
5461
5521
5581
5641
5701
5761
5821
5881
5941
6001
6061
6121
ATGGCCAGTG GCGCCTGTCA GGGCTGCGAA GAGGAAGAGG AGGAGGAGGC TCTGAAGAAG 
TTGATAGTCA GGCTGAATAA TGTCCAGGAA GGCAAGCAGA TCGAGACGTT GCTTCAGCTC
CTGGAGGACA TGCTGGTGTT CACCTACTCG GACCGCGCCT CCAAGTTATT TGAAGATAAA
AATTTCCACG TGCCTCTGTT GATTGTCCTG GACTCCTACA TGAGAGTTGC CAGTGTACAG
CAGGCGGGGT GGTCACTTCT GTGCAAATTA ATAGAAGTCT GTCCAGGGAC ATTGCAAAGC
TTAATAGGAC CCCAGGATAT TGGAAATGAT TGGGAAGTCC TTGGTATTCA CCGGCTGATT
CTTAAAATGT TAACTGTTCA TCACGCCAAT GTAAACCTGT CAATAGTTGG ACTAAAAGCC
TTGGATCTCC TCCTAGATTC AGGTAAACTC ACCTTGCTGA TACTGGATGA AGAATGTGAT
ATTTTCTTGT TAATTTTTGA TGCCATGCAC AGATATTCAG CCAATGATGA AGTCCAAAAA
CTGGGATGCA AAGCTTTACA CGTGCTTTTT GAGAGAGTTT CCGAGGAACA GCTGACTGAG
TTTGTGGAGA ACAAAGATTA CACGATACTG CTGAGTACGT TCGGCAGCTT CAGAAGGGAC
AAGGAGATTG TGTACCACGT ACTTTGCTGC TTGCATTCCC TGGCGGTTAC ATGCAGCAAT
GTAGAGGTCC TCATGAGTGG GAATGTCCGG TGCTACAATC TTGTGGTGGA GGCCATGAAA
GCCTTCCCCA CCAATGAAAA CATCCAAGAG GTGAGCTGCT CCTTGTTCCA GAAGCTTACA
TTAGGTAACT TTTTCAACAT CCTGGTGTTG AACGAAGTGC ATGTCTTTGT GGTGAAAGCG
GTCCGACAGT ATCCTGAGAA CGCAGCCTTA CAGATCTCTG CACTCAGCTG TTTAGCACTC
CTCACTGAGA CTATTTTCTT AAACCAAGAC TTGGAGGAAA GAAGTGAGAC TCAAGAGCAG
AGCGAAGAGG AAGACAGTGA GAAGCTTTTC TGGCTGGAAC CCTGCTATAA AGCCCTGGTG
CGCCATCGAA AGGACAAACA CGTGCAGGAG GCTGCCTGCT GGGCACTAAA TAACCTCCTT
ATGTACCAGA ACAGTTTGCA TGAGAAGATC GGAGATGAAG ATGGCCAGTT CCCTGCGCAC
AGGGAAGTGA TGCTGTCTAT GCTGATGCAC TCTTCTTCCA AAGATGTCTT CCAAGCAGCT
GCACATGCTC TGTCCACTCT CTTGGAACAA AATGTTAATT TCAGGAAAAT CCTGCTGGCA
AAAGGAGTAT ACCTGAATGT CTTGGAATTG ATGCAGAAGC ATGCCCATGC GCCTGAGGTG
GCAGAGAGTG GCTGCAAGAT GCTGAGTCAC CTGTTTGAAG GAAGTAACCC TTCTCTGGAT
ACAATGGCAG CAGTGGTCCC TAAAATACTA ACAGTGATGA AAGCCCACGG AACGTCTCTG
TCAGTCCAGC TGGAGGCGCT GCGAGCTATC TTGCATTTCG TTGTGCCAGG ACTATTGGAA
GAATCCAGGG AGGACTCTCA ATGCAGACCA AATGTGCTCA GAAAACAGTG TTTCAGGACT
GACATCCACA AGCTGGTTCT AGTCGCTCTG AACAGGTTCA TTGGGAATCC TGGGATTCAG
AAATGTGGAT TGAAAGTAAT CTCTTCTCTC GCGCACCTTC CTGATGCCAC AGAGACATTG
TCCCTGCAAG GAGCAGTTGA CTCAGTCCTC CACACCTTAC AGATGTATCC AGATGACCAA
GAAATTCAGT GTCTGGGCTT ACACCTTATG GGATGCTTGA TGACAAAGAA GAATTTCTGC
ATAGGGACAG GGCACCTCCT GGCAAAAATT CTGGCTTCCA CTTTGCAGCG CTTTAAAGAT
GTTGCTGAGG TGCAGACTAC AGGATTACAG ACAACCCTGT CAATACTTGA GCTGTCAGTA
TCTTTCTCCA AGCTGCTAGT GCACTATTCC TTTGATGTGG TGATATTTCA TCAGATGTCT
TCCAGTGTTG TAGAACAAAA GGATGAGCAG TTCCTCAATC TATGTTGCAA ATGCTTTGCA
AAAGTGGCCG TGGATGATGA GCTGAAAAAC ACCATGCTAG AGAGAGCCTG CGATCAGAAT
AACAGCATCA TGGTTGAATG TTTGCTCCTC TTGGGAGCTG ATGCCAACCA AGTGAAGGGG
GCAACTTCTT TAATCTATCA GGTATGTGAG AAAGAGAGCA GTCCTAAATT GGTGGAACTG
TTGCTTAATG GTGGTTGTCG TGAACAAGAT GTACGGAAGG CCCTGACCGT AAGCATCCAA
AAGGGCGACA GCCAGGTCAT CAGCTTGCTC CTCAGGAAAC TTGCCCTGGA CCTGGCCAAC
AACAGCATTT GCCTTGGAGG ATTTGGCATA GGAAAAATTG ATCCTTCTTG GCTTGGTCCT
TTATTTCCAG ATAAGTCATC CAATTTAAGG AAGCAAACAA ACACAGGATC TGTCCTAGCG
AGGAAAGTGC TCCGGTATCA GATGAGAAAC ACCCTTCAAG AAGGCGTGGC CTCAGGCAGT
GACGGCAAGT TTTCTGAAGA CGCGCTGGCG AAATTTGGAG AATGGACCTT TATTCCCGAC
TCTTCTATGG ACAGTGTGTT TGGCCAGAGC GATGATCTGG ATAGCGAAGG CAGCGAGAGC
TCATTTCTCG TGAAGAGGAA GTCCAACTCA ATTAGTGTAG GGGAAGTTTA CAGAGATCTA
GCTCTGCAGC GCTGCTCACC AAATGCTCAG AGGCATTCCA ATTCGCTGGG TCCTGTTTTT
GACCATGAAG ACTTACTGAG ACGAAAAAGA AAAATACTGT CTTCAGATGA GTCTCTCAGG
TCCTCAAGGC TGCCGTCCCA TATGAGGCAA TCAGATAGCT CTTCTTCCCT GGCTTCTGAG
AGAGAACACA TCACGTCGTT AGACCTATCT GCCAACGAAC TCAAAGATAT TGATGCTCTG
AGCCAGAAGT GTTGCCTCAG TAGCCACCTG GAACATCTCA CCAAACTGGA ACTTCACCAG
AATTCACTCA CGAGCTTCCC ACAGCAGCTG TGTGAGACTC TGAAGTGTTT GATACACTTG
GATTTGCACA GTAACAAATT CACCTCATTT CCCTCTTTCG TGTTGAAAAT GCCACGTATC
ACCAACCTAG ATGCCTCTCG AAATGACATC GGGCCAACAG TAGTTTTAGA CCCTGCGATG
AAGTGTCCAA GCCTCAAACA GTTGAATCTG TCCTATAACC AGCTCTCTTC AATCCCAGAG
AATCTTGCCC AAGTGGTGGA GAAACTTGAG CAGCTCCTAC TGGAAGGAAA TAAAATATCC
GGGATTTGCT CTCCCCTGAG CCTGAAGGAA CTGAAGATTT TAAATCTTAG TAAAAATCAC
ATTCCATCCC TACCTGGAGA TTTTCTTGAG GCTTGTTCAA AAGTCGAGAG TTTCAGTGCT
CGCATGAATT TTCTTGCTGC AATGCCTGCC TTACCTTCTT CCATAACGAG CTTAAAATTG
TCTCAGAACT CTTTCACGTG CATTCCAGAA GCGATTTTCA GTCTTCCGCA CTTGCGGTCC
TTGGATATGA GCCACAACAA CATTGAATGT CTGCCGGGAC CTGCACATTG GAAGTCTCTG
AACTTAAGGG AACTCATTTT TAGCAAGAAT CAGATCAGCA CCTTAGACTT TAGTGAGAAC
CCACACGTGT GGTCAAGAGT AGAGAAACTG CATCTCTCTC ATAATAAACT GAAAGAGATT
CCTCCAGAAA TTGGCTGCCT TGAAAATCTG ACGTCTCTCG ACGTCAGTTA CAACTTGGAA
CTGAGGTCCT TCCCAAATGA AATGGGGAAG TTGAGCAAGA TATGGGATCT TCCCTTGGAC
GGACTGCATC TGAATTTTGA CTTTAAGCAC GTAGGATGCA AGGCCAAAGA CATCATAAGG
TTTCTACAAC AACGTCTGAA AAAGGCTGTA CCCTACAACC GAATGAAGCT CATGATTGTG
GGAAATACGG GGAGCGGTAA GACCACTTTA CTGCAACAAC TCATGAAAAT GAAGAAACCA
GAACTTGGCA TGCAGGGTGC CACAGTCGGC ATAGACGTGC GAGACTGGTC CATCCAAATA
CGGGGCAAAA GGAGAAAGGA CCTGGTTCTA AACGTGTGGG ATTTTGCAGG TCGTGAGGAA
TTCTACAGCA CTCACCCCCA CTTCATGACC CAGAGAGCCC TCTACCTGGC TGTCTATGAT
CTCAGCAAGG GGCAGGCAGA GGTGGACGCC ATGAAGCCCT GGCTCTTCAA TATCAAGGCT
CGTGCCTCTT CTTCCCCGGT GATTCTGGTG GGCACACATT TGGATGTTTC TGATGAGAAG
CAGCGGAAAG CGTGCATAAG CAAAATCACG AAGGAACTCC TAAATAAGCG AGGATTCCCC
ACCATCCGGG ACTACCACTT TGTGAATGCC ACCGAGGAGT CAGATGCGCT GGCAAAGCTT
CGGAAAACCA TCATAAATGA GAGCCTTAAT TTCAAGATCC GAGATCAGCC TGTGGTTGGG
CAGCTAATTC CAGATTGCTA CGTAGAACTG GAGAAAATCA TTTTATCAGA GCGGAAAGCT
GTGCCGACTG AGTTTCCTGT GATTAACCGG AAACACCTGT TACAGCTCGT GAACGAACAT
CAGCTGCAGC TGGATGAGAA CGAGCTCCCA CACGCCGTTC ACTTCCTAAA TGAGTCGGGA
GTTCTTCTGC ATTTTCAAGA CCCTGCCCTG CAGCTAAGTG ACCTGTACTT TGTGGAACCC
AAGTGGCTTT GTAAAGTCAT GGCACAGATC TTGACAGTGA AGGTAGACGG CTGTCTGAAA
CATCCTAAGG GCATCATTTC CCGGAGAGAT GTGGAAAAAT TCCTTTCAAA GAAGAAGCGA
TTCCCGAAGA ACTATATGAT GCAATACTTT AAACTATTAG AAAAATTTCA GATCGCATTG
CCAATAGGGG AAGAATATCT TCTGGTTCCA AGCAGCTTGT CTGACCACAG GCCAGTGATA
GAGCTCCCCC ACTGTGAGAA CTCTGAGATC ATCATCCGGC TGTACGAAAT GCCGTACTTT
CCCATGGGAT TTTGGTCAAG ATTGATTAAC CGATTACTTG AAATCTCACC CTTCATGCTT
TCTGGCAGAG AGAGAGCACT ACGCCCTAAC AGGATGTATT GGCGGCAAGG CATCTACTTG
AATTGGTCTC CAGAAGCATA CTGTCTGGTA GGCTCTGAAG TCTTAGACAA TCGACCTGAG
AGTTTCTTGA AAATCACAGT TCCGTCTTGT AGAAAAGGTT GTATTCTTCT GGGCCGAGTT
GTGGATCATA TTGACTCACT CATGGAAGAA TGGTTTCCCG GGTTACTGGA GATTGACATT
TGTGGGGAAG GAGAAACTCT GTTGAAGAAA TGGGCATTGT ACAGTTTTAA TGATGGTGAA
GAACATCAGA AGATCTTGCT TGATGAGTTG ATGAAGAAGG CTGAAGAAGG AGACCTGTTA
ATAAATCCAG ACCAACCAAG GCTCACTATT CCAATATCCC AGATTGCTCC GGACTTGATC
TTGGCTGACC TGCCTAGAAA TATCATGTTG AACAATGATG AGTTGGAATT TGAGGAAGCA
CCAGAGTTTC TCTTAGGCGA TGGAAGTTTT GGATCCGTTT ATCGAGCTGC CTACGAAGGA
GAGGAAGTGG CTGTGAAGAT TTTTAATAAG CACACATCTC TTAGGCTGTT AAGACAAGAG
TTGGTGGTCC TTTGTCACCT TCACCACCCC AGCCTGATAT CCTTGCTGGC GGCTGGTATT
CGTCCTCGGA TGTTGGTAAT GGAGTTGGCC TCCAAAGGTT CCTTGGATCG CCTGCTGCAG
CAGGACAAAG CCAGCCTCAC CAGAACCCTC CAGCACAGGA TCGCGTTGCA TGTGGCCGAC
GGCCTGAGGT ATCTCCACTC AGCCATGATT ATTTACCGTG ACCTGAAGCC CCACAATGTG
CTGCTTTTTA CCCTGTATCC CAATGCTGCC ATCATTGCGA AGATTGCGGA CTACGGGATC
GCACAGTACT GCTGCAGGAT GGGAATAAAG ACATCAGAGG GCACCCCAGA GGCTTTGTCC
ACTTATGTGA CAGCGGTCGT CTCTGCGTTC TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006521340.1
CDS473..6625
Misc Feature(1)3425..3508
Misc Feature(2)3428..4192
Misc Feature(3)order(3431..3433,3437..3439,3446..3448,3452..3454,3509..3511,3518..3520,3524..3526,3533..3535,3539..3541,3581..3583,3590..3592,3596..3598,3605..3607,3611..3613,3650..3652,3659..3661,3665..3667,3674..3676,3680..3682,3725..3727,3734..3736,3740..3742,3749..3751,3755..3757,3797..3799,3806..3808,3812..3814,3821..3823,3827..3829,3863..3865,3872..3874,3878..3880,3887..3889,3935..3937,3944..3946,3950..3952,3959..3961,3995..3997,4004..4006,4010..4012,4019..4021,4025..4027,4064..4066,4073..4075,4079..4081,4088..4090,4094..4096,4166..4168,4175..4177,4181..4183,4190..4192)
Misc Feature(4)3506..3682
Misc Feature(5)3509..3580
Misc Feature(6)order(3527..3532,3671..3673,3818..3820,3884..3886,4016..4018,4076..4078,4082..4084,4178..4180)
Misc Feature(7)3581..3649
Misc Feature(8)3644..3829
Misc Feature(9)3650..3724
Misc Feature(10)3725..3796
Misc Feature(11)3797..3862
Misc Feature(12)3857..4096
Misc Feature(13)3863..3982
Misc Feature(14)3983..4063
Misc Feature(15)4064..4135
Misc Feature(16)4133..4309
Misc Feature(17)4136..4210
Misc Feature(18)4280..4345
Misc Feature(19)4469..5125
Misc Feature(20)4472..4993
Misc Feature(21)4493..4516
Misc Feature(22)order(4508..4519,4661..4663,4826..4831,4835..4837,4937..4945)
Misc Feature(23)4574..4576
Misc Feature(24)4586..4594
Misc Feature(25)4652..4663
Misc Feature(26)order(4658..4663,4709..4714)
Misc Feature(27)4826..4837
Misc Feature(28)4937..4945
Misc Feature(29)5051..5692
Misc Feature(30)6122..>6580
Misc Feature(31)order(6122..6133,6140..6142,6146..6148,6182..6184,6188..6190,6269..6271,6311..6322,6452..6454,6464..6469,6473..6475,6518..6523)
Translation

Target ORF information:

RefSeq Version XM_006521277.3
Organism Mus musculus(House mouse)
Definition Mus musculus leucine-rich repeat kinase 2 (Lrrk2), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006521277.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
4981
5041
5101
5161
5221
5281
5341
5401
5461
5521
5581
5641
5701
5761
5821
5881
5941
6001
6061
6121
ATGGCCAGTG GCGCCTGTCA GGGCTGCGAA GAGGAAGAGG AGGAGGAGGC TCTGAAGAAG 
TTGATAGTCA GGCTGAATAA TGTCCAGGAA GGCAAGCAGA TCGAGACGTT GCTTCAGCTC
CTGGAGGACA TGCTGGTGTT CACCTACTCG GACCGCGCCT CCAAGTTATT TGAAGATAAA
AATTTCCACG TGCCTCTGTT GATTGTCCTG GACTCCTACA TGAGAGTTGC CAGTGTACAG
CAGGCGGGGT GGTCACTTCT GTGCAAATTA ATAGAAGTCT GTCCAGGGAC ATTGCAAAGC
TTAATAGGAC CCCAGGATAT TGGAAATGAT TGGGAAGTCC TTGGTATTCA CCGGCTGATT
CTTAAAATGT TAACTGTTCA TCACGCCAAT GTAAACCTGT CAATAGTTGG ACTAAAAGCC
TTGGATCTCC TCCTAGATTC AGGTAAACTC ACCTTGCTGA TACTGGATGA AGAATGTGAT
ATTTTCTTGT TAATTTTTGA TGCCATGCAC AGATATTCAG CCAATGATGA AGTCCAAAAA
CTGGGATGCA AAGCTTTACA CGTGCTTTTT GAGAGAGTTT CCGAGGAACA GCTGACTGAG
TTTGTGGAGA ACAAAGATTA CACGATACTG CTGAGTACGT TCGGCAGCTT CAGAAGGGAC
AAGGAGATTG TGTACCACGT ACTTTGCTGC TTGCATTCCC TGGCGGTTAC ATGCAGCAAT
GTAGAGGTCC TCATGAGTGG GAATGTCCGG TGCTACAATC TTGTGGTGGA GGCCATGAAA
GCCTTCCCCA CCAATGAAAA CATCCAAGAG GTGAGCTGCT CCTTGTTCCA GAAGCTTACA
TTAGGTAACT TTTTCAACAT CCTGGTGTTG AACGAAGTGC ATGTCTTTGT GGTGAAAGCG
GTCCGACAGT ATCCTGAGAA CGCAGCCTTA CAGATCTCTG CACTCAGCTG TTTAGCACTC
CTCACTGAGA CTATTTTCTT AAACCAAGAC TTGGAGGAAA GAAGTGAGAC TCAAGAGCAG
AGCGAAGAGG AAGACAGTGA GAAGCTTTTC TGGCTGGAAC CCTGCTATAA AGCCCTGGTG
CGCCATCGAA AGGACAAACA CGTGCAGGAG GCTGCCTGCT GGGCACTAAA TAACCTCCTT
ATGTACCAGA ACAGTTTGCA TGAGAAGATC GGAGATGAAG ATGGCCAGTT CCCTGCGCAC
AGGGAAGTGA TGCTGTCTAT GCTGATGCAC TCTTCTTCCA AAGATGTCTT CCAAGCAGCT
GCACATGCTC TGTCCACTCT CTTGGAACAA AATGTTAATT TCAGGAAAAT CCTGCTGGCA
AAAGGAGTAT ACCTGAATGT CTTGGAATTG ATGCAGAAGC ATGCCCATGC GCCTGAGGTG
GCAGAGAGTG GCTGCAAGAT GCTGAGTCAC CTGTTTGAAG GAAGTAACCC TTCTCTGGAT
ACAATGGCAG CAGTGGTCCC TAAAATACTA ACAGTGATGA AAGCCCACGG AACGTCTCTG
TCAGTCCAGC TGGAGGCGCT GCGAGCTATC TTGCATTTCG TTGTGCCAGG ACTATTGGAA
GAATCCAGGG AGGACTCTCA ATGCAGACCA AATGTGCTCA GAAAACAGTG TTTCAGGACT
GACATCCACA AGCTGGTTCT AGTCGCTCTG AACAGGTTCA TTGGGAATCC TGGGATTCAG
AAATGTGGAT TGAAAGTAAT CTCTTCTCTC GCGCACCTTC CTGATGCCAC AGAGACATTG
TCCCTGCAAG GAGCAGTTGA CTCAGTCCTC CACACCTTAC AGATGTATCC AGATGACCAA
GAAATTCAGT GTCTGGGCTT ACACCTTATG GGATGCTTGA TGACAAAGAA GAATTTCTGC
ATAGGGACAG GGCACCTCCT GGCAAAAATT CTGGCTTCCA CTTTGCAGCG CTTTAAAGAT
GTTGCTGAGG TGCAGACTAC AGGATTACAG ACAACCCTGT CAATACTTGA GCTGTCAGTA
TCTTTCTCCA AGCTGCTAGT GCACTATTCC TTTGATGTGG TGATATTTCA TCAGATGTCT
TCCAGTGTTG TAGAACAAAA GGATGAGCAG TTCCTCAATC TATGTTGCAA ATGCTTTGCA
AAAGTGGCCG TGGATGATGA GCTGAAAAAC ACCATGCTAG AGAGAGCCTG CGATCAGAAT
AACAGCATCA TGGTTGAATG TTTGCTCCTC TTGGGAGCTG ATGCCAACCA AGTGAAGGGG
GCAACTTCTT TAATCTATCA GGTATGTGAG AAAGAGAGCA GTCCTAAATT GGTGGAACTG
TTGCTTAATG GTGGTTGTCG TGAACAAGAT GTACGGAAGG CCCTGACCGT AAGCATCCAA
AAGGGCGACA GCCAGGTCAT CAGCTTGCTC CTCAGGAAAC TTGCCCTGGA CCTGGCCAAC
AACAGCATTT GCCTTGGAGG ATTTGGCATA GGAAAAATTG ATCCTTCTTG GCTTGGTCCT
TTATTTCCAG ATAAGTCATC CAATTTAAGG AAGCAAACAA ACACAGGATC TGTCCTAGCG
AGGAAAGTGC TCCGGTATCA GATGAGAAAC ACCCTTCAAG AAGGCGTGGC CTCAGGCAGT
GACGGCAAGT TTTCTGAAGA CGCGCTGGCG AAATTTGGAG AATGGACCTT TATTCCCGAC
TCTTCTATGG ACAGTGTGTT TGGCCAGAGC GATGATCTGG ATAGCGAAGG CAGCGAGAGC
TCATTTCTCG TGAAGAGGAA GTCCAACTCA ATTAGTGTAG GGGAAGTTTA CAGAGATCTA
GCTCTGCAGC GCTGCTCACC AAATGCTCAG AGGCATTCCA ATTCGCTGGG TCCTGTTTTT
GACCATGAAG ACTTACTGAG ACGAAAAAGA AAAATACTGT CTTCAGATGA GTCTCTCAGG
TCCTCAAGGC TGCCGTCCCA TATGAGGCAA TCAGATAGCT CTTCTTCCCT GGCTTCTGAG
AGAGAACACA TCACGTCGTT AGACCTATCT GCCAACGAAC TCAAAGATAT TGATGCTCTG
AGCCAGAAGT GTTGCCTCAG TAGCCACCTG GAACATCTCA CCAAACTGGA ACTTCACCAG
AATTCACTCA CGAGCTTCCC ACAGCAGCTG TGTGAGACTC TGAAGTGTTT GATACACTTG
GATTTGCACA GTAACAAATT CACCTCATTT CCCTCTTTCG TGTTGAAAAT GCCACGTATC
ACCAACCTAG ATGCCTCTCG AAATGACATC GGGCCAACAG TAGTTTTAGA CCCTGCGATG
AAGTGTCCAA GCCTCAAACA GTTGAATCTG TCCTATAACC AGCTCTCTTC AATCCCAGAG
AATCTTGCCC AAGTGGTGGA GAAACTTGAG CAGCTCCTAC TGGAAGGAAA TAAAATATCC
GGGATTTGCT CTCCCCTGAG CCTGAAGGAA CTGAAGATTT TAAATCTTAG TAAAAATCAC
ATTCCATCCC TACCTGGAGA TTTTCTTGAG GCTTGTTCAA AAGTCGAGAG TTTCAGTGCT
CGCATGAATT TTCTTGCTGC AATGCCTGCC TTACCTTCTT CCATAACGAG CTTAAAATTG
TCTCAGAACT CTTTCACGTG CATTCCAGAA GCGATTTTCA GTCTTCCGCA CTTGCGGTCC
TTGGATATGA GCCACAACAA CATTGAATGT CTGCCGGGAC CTGCACATTG GAAGTCTCTG
AACTTAAGGG AACTCATTTT TAGCAAGAAT CAGATCAGCA CCTTAGACTT TAGTGAGAAC
CCACACGTGT GGTCAAGAGT AGAGAAACTG CATCTCTCTC ATAATAAACT GAAAGAGATT
CCTCCAGAAA TTGGCTGCCT TGAAAATCTG ACGTCTCTCG ACGTCAGTTA CAACTTGGAA
CTGAGGTCCT TCCCAAATGA AATGGGGAAG TTGAGCAAGA TATGGGATCT TCCCTTGGAC
GGACTGCATC TGAATTTTGA CTTTAAGCAC GTAGGATGCA AGGCCAAAGA CATCATAAGG
TTTCTACAAC AACGTCTGAA AAAGGCTGTA CCCTACAACC GAATGAAGCT CATGATTGTG
GGAAATACGG GGAGCGGTAA GACCACTTTA CTGCAACAAC TCATGAAAAT GAAGAAACCA
GAACTTGGCA TGCAGGGTGC CACAGTCGGC ATAGACGTGC GAGACTGGTC CATCCAAATA
CGGGGCAAAA GGAGAAAGGA CCTGGTTCTA AACGTGTGGG ATTTTGCAGG TCGTGAGGAA
TTCTACAGCA CTCACCCCCA CTTCATGACC CAGAGAGCCC TCTACCTGGC TGTCTATGAT
CTCAGCAAGG GGCAGGCAGA GGTGGACGCC ATGAAGCCCT GGCTCTTCAA TATCAAGGCT
CGTGCCTCTT CTTCCCCGGT GATTCTGGTG GGCACACATT TGGATGTTTC TGATGAGAAG
CAGCGGAAAG CGTGCATAAG CAAAATCACG AAGGAACTCC TAAATAAGCG AGGATTCCCC
ACCATCCGGG ACTACCACTT TGTGAATGCC ACCGAGGAGT CAGATGCGCT GGCAAAGCTT
CGGAAAACCA TCATAAATGA GAGCCTTAAT TTCAAGATCC GAGATCAGCC TGTGGTTGGG
CAGCTAATTC CAGATTGCTA CGTAGAACTG GAGAAAATCA TTTTATCAGA GCGGAAAGCT
GTGCCGACTG AGTTTCCTGT GATTAACCGG AAACACCTGT TACAGCTCGT GAACGAACAT
CAGCTGCAGC TGGATGAGAA CGAGCTCCCA CACGCCGTTC ACTTCCTAAA TGAGTCGGGA
GTTCTTCTGC ATTTTCAAGA CCCTGCCCTG CAGCTAAGTG ACCTGTACTT TGTGGAACCC
AAGTGGCTTT GTAAAGTCAT GGCACAGATC TTGACAGTGA AGGTAGACGG CTGTCTGAAA
CATCCTAAGG GCATCATTTC CCGGAGAGAT GTGGAAAAAT TCCTTTCAAA GAAGAAGCGA
TTCCCGAAGA ACTATATGAT GCAATACTTT AAACTATTAG AAAAATTTCA GATCGCATTG
CCAATAGGGG AAGAATATCT TCTGGTTCCA AGCAGCTTGT CTGACCACAG GCCAGTGATA
GAGCTCCCCC ACTGTGAGAA CTCTGAGATC ATCATCCGGC TGTACGAAAT GCCGTACTTT
CCCATGGGAT TTTGGTCAAG ATTGATTAAC CGATTACTTG AAATCTCACC CTTCATGCTT
TCTGGCAGAG AGAGAGCACT ACGCCCTAAC AGGATGTATT GGCGGCAAGG CATCTACTTG
AATTGGTCTC CAGAAGCATA CTGTCTGGTA GGCTCTGAAG TCTTAGACAA TCGACCTGAG
AGTTTCTTGA AAATCACAGT TCCGTCTTGT AGAAAAGGTT GTATTCTTCT GGGCCGAGTT
GTGGATCATA TTGACTCACT CATGGAAGAA TGGTTTCCCG GGTTACTGGA GATTGACATT
TGTGGGGAAG GAGAAACTCT GTTGAAGAAA TGGGCATTGT ACAGTTTTAA TGATGGTGAA
GAACATCAGA AGATCTTGCT TGATGAGTTG ATGAAGAAGG CTGAAGAAGG AGACCTGTTA
ATAAATCCAG ACCAACCAAG GCTCACTATT CCAATATCCC AGATTGCTCC GGACTTGATC
TTGGCTGACC TGCCTAGAAA TATCATGTTG AACAATGATG AGTTGGAATT TGAGGAAGCA
CCAGAGTTTC TCTTAGGCGA TGGAAGTTTT GGATCCGTTT ATCGAGCTGC CTACGAAGGA
GAGGAAGTGG CTGTGAAGAT TTTTAATAAG CACACATCTC TTAGGCTGTT AAGACAAGAG
TTGGTGGTCC TTTGTCACCT TCACCACCCC AGCCTGATAT CCTTGCTGGC GGCTGGTATT
CGTCCTCGGA TGTTGGTAAT GGAGTTGGCC TCCAAAGGTT CCTTGGATCG CCTGCTGCAG
CAGGACAAAG CCAGCCTCAC CAGAACCCTC CAGCACAGGA TCGCGTTGCA TGTGGCCGAC
GGCCTGAGGT ATCTCCACTC AGCCATGATT ATTTACCGTG ACCTGAAGCC CCACAATGTG
CTGCTTTTTA CCCTGTATCC CAATGCTGCC ATCATTGCGA AGATTGCGGA CTACGGGATC
GCACAGTACT GCTGCAGGAT GGGAATAAAG ACATCAGAGG GCACCCCAGA GGCTTTGTCC
ACTTATGTGA CAGCGGTCGT CTCTGCGTTC TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Phos-tag analysis of Rab10 phosphorylation by LRRK2: a powerful assay for assessing kinase function and inhibitors.
The Biochemical journal473(17)2671-85(2016 Sep)
Ito G,Katsemonova K,Tonelli F,Lis P,Baptista MA,Shpiro N,Duddy G,Wilson S,Ho PW,Ho SL,Reith AD,Alessi DR


book

LRRK2 modulates microglial activity through regulation of chemokine (C-X3-C) receptor 1 -mediated signalling pathways.
Human molecular genetics25(16)3515-3523(2016 Aug)
Ma B,Xu L,Pan X,Sun L,Ding J,Xie C,Koliatsos VE,Cai H


book

Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts.
Proceedings of the National Academy of Sciences of the United States of America113(30)E4357-66(2016 Jul)
Guaitoli G,Raimondi F,Gilsbach BK,Gómez-Llorente Y,Deyaert E,Renzi F,Li X,Schaffner A,Jagtap PK,Boldt K,von Zweydorf F,Gotthardt K,Lorimer DD,Yue Z,Burgin A,Janjic N,Sattler M,Versées W,Ueffing M,Ubarretxena-Belandia I,Kortholt A,Gloeckner CJ


book

Altered Expression of
BioMed research international20167681259(2016)
Wu B,Xiao K,Zhang Z,Ma L


book

Long Non-coding RNA HOTAIR Promotes Parkinson's Disease Induced by MPTP Through up-regulating the Expression of LRRK2.
Current neurovascular research13(2)115-20(2016)
Liu S,Cui B,Dai ZX,Shi PK,Wang ZH,Guo YY


 
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