Gene Symbol | Baiap2l1 |
Entrez Gene ID | 66898 |
Full Name | BAI1-associated protein 2-like 1 |
Synonyms | 1300006M19Rik,AI585895,IRTKS |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Baiap2l1 cDNA ORF clone
Gene Symbol | Baiap2l1 |
Entrez Gene ID | 66898 |
Full Name | BAI1-associated protein 2-like 1 |
Synonyms | 1300006M19Rik,AI585895,IRTKS |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_025833.3 | NP_080109.1 | brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 |
Canis lupus familiaris (dog) | BAIAP2L1 | XP_536876.4 |
Pan troglodytes (chimpanzee) | BAIAP2L1 | XP_519222.3 |
Xenopus tropicalis (tropical clawed frog) | baiap2l1 | NP_001093697.1 |
Mus musculus (house mouse) | Baiap2l1 | NP_080109.1 |
Rattus norvegicus (Norway rat) | Baiap2l1 | NP_001029312.1 |
Danio rerio (zebrafish) | baiap2l1b | NP_001017830.1 |
Homo sapiens (human) | BAIAP2L1 | NP_061330.2 |
BAIAP2L1 | XP_001110709.2 | |
Bos taurus (cattle) | BAIAP2L1 | XP_003587892.1 |
Gallus gallus (chicken) | BAIAP2L1 | NP_001264458.1 |
Danio rerio (zebrafish) | baiap2l1a | NP_944604.1 |
Redundant functions of I-BAR family members, IRSp53 and IRTKS, are essential for embryonic development.
Chou AM, Sem KP, Lam WJ, Ahmed S, Lim CY
Scientific reports740485(2017 Jan)
The Rho GTPase Rif signals through IRTKS, Eps8 and WAVE2 to generate dorsal membrane ruffles and filopodia.
Sudhaharan T, Sem KP, Liew HF, Yu YH, Goh WI, Chou AM, Ahmed S
Journal of cell science129(14)2829-40(2016 07)
IRTKS negatively regulates antiviral immunity through PCBP2 sumoylation-mediated MAVS degradation.
Xia P, Wang S, Xiong Z, Ye B, Huang LY, Han ZG, Fan Z
Nature communications68132(2015 Sep)
Deficiency of IRTKS as an adaptor of insulin receptor leads to insulin resistance.
Huang LY, Wang YP, Wei BF, Yang J, Wang JQ, Wu BH, Zhang ZZ, Hou YY, Sun WM, Hu RM, Ning G, Han ZG
Cell research23(11)1310-21(2013 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Rho family GTPases use the I-BAR proteins, IRSp53 (also known as BAIAP2), IRTKS and Pinkbar, as a central mechanism to modulate cell morphology.
Title: The Rho GTPase Rif signals through IRTKS, Eps8 and WAVE2 to generate dorsal membrane ruffles and filopodia.
IRTKS functions as a negative modulator of excessive inflammation in viral infections.
Title: IRTKS negatively regulates antiviral immunity through PCBP2 sumoylation-mediated MAVS degradation.
The IRTKS, as an adaptor of the insulin receptor (IR), modulates IR-IRS1-PI3K-AKT signaling via regulating the phosphorylation of IR.
Title: Deficiency of IRTKS as an adaptor of insulin receptor leads to insulin resistance.
The following Baiap2l1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Baiap2l1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu01121 | |
Clone ID Related Accession (Same CDS sequence) | NM_025833.3 | |
Accession Version | NM_025833.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1545bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-25 | |
Organism | Mus musculus(house mouse) | |
Product | brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK004918.2 and AV224233.1. On Apr 15, 2006 this sequence version replaced NM_025833.2. ##Evidence-Data-START## Transcript exon combination :: AK004918.2, BC015459.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGTCTCGGG GGCCGGAGGA GGTGAACCGG CTCACGGAGA ACACGTACCG GAATGTGATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_080109.1 |
CDS | 272..1816 |
Translation |
Target ORF information:
Target ORF information:
|
NM_025833.3 |
1 | ATGTCTCGGG GGCCGGAGGA GGTGAACCGG CTCACGGAGA ACACGTACCG GAATGTGATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Redundant functions of I-BAR family members, IRSp53 and IRTKS, are essential for embryonic development. |
The Rho GTPase Rif signals through IRTKS, Eps8 and WAVE2 to generate dorsal membrane ruffles and filopodia. |
IRTKS negatively regulates antiviral immunity through PCBP2 sumoylation-mediated MAVS degradation. |
Deficiency of IRTKS as an adaptor of insulin receptor leads to insulin resistance. |