Nrarp cDNA ORF clone, Mus musculus(house mouse)
| Gene Symbol | Nrarp |
| Entrez Gene ID | 67122 |
| Full Name | Notch-regulated ankyrin repeat protein |
| Synonyms | 2700054M22Rik |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_025980.2 | NP_080256.2 | notch-regulated ankyrin repeat-containing protein |
| LOC720929 | XP_001116892.1 | |
| Rattus norvegicus (Norway rat) | Nrarp | NP_001137222.1 |
| Danio rerio (zebrafish) | nrarpa | NP_852472.1 |
| Homo sapiens (human) | NRARP | NP_001004354.1 |
| Pan troglodytes (chimpanzee) | NRARP | XP_528519.1 |
| Gallus gallus (chicken) | NRARP | XP_428951.2 |
| Canis lupus familiaris (dog) | NRARP | XP_005625115.1 |
| Bos taurus (cattle) | NRARP | XP_005213553.1 |
| Mus musculus (house mouse) | Nrarp | NP_080256.2 |
Related articles in PubMed
Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer.
Lim JS, Ibaseta A, Fischer MM, Cancilla B, O'Young G, Cristea S, Luca VC, Yang D, Jahchan NS, Hamard C, Antoine M, Wislez M, Kong C, Cain J, Liu YW, Kapoun AM, Garcia KC, Hoey T, Murriel CL, Sage J
Nature545(7654)360-364(2017 05)
Carbohydrate-binding protein CLEC14A regulates VEGFR-2- and VEGFR-3-dependent signals during angiogenesis and lymphangiogenesis.
Lee S, Rho SS, Park H, Park JA, Kim J, Lee IK, Koh GY, Mochizuki N, Kim YM, Kwon YG
The Journal of clinical investigation127(2)457-471(2017 Feb)
Disruption of somitogenesis by a novel dominant allele of Lfng suggests important roles for protein processing and secretion.
Williams DR, Shifley ET, Braunreiter KM, Cole SE
Development (Cambridge, England)143(5)822-30(2016 Mar)
Spatiotemporal regulation of GLI target genes in the mammalian limb bud.
Lewandowski JP, Du F, Zhang S, Powell MB, Falkenstein KN, Ji H, Vokes SA
Developmental biology406(1)92-103(2015 Oct)
Transcript processing and export kinetics are rate-limiting steps in expressing vertebrate segmentation clock genes.
Hoyle NP, Ish-Horowicz D
Proceedings of the National Academy of Sciences of the United States of America110(46)E4316-24(2013 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The transcription and expression patterns of Notch pathway components (Notch 1-3, Delta1 and 4, Jagged1) and effectors (Hes1, Hes2, Hes5 and Nrarp) were evaluated in the mouse testis
Title: Dynamics of Notch pathway expression during mouse testis post-natal development and along the spermatogenic cycle.
Nrarp is essential for forming the proper number and morphology of axial skeleton components
Title: The period of the somite segmentation clock is sensitive to Notch activity.
Cyclic Nrarp mRNA expression is regulated by the somitic oscillator but Nrarp protein levels do not oscillate.
Title: Cyclic Nrarp mRNA expression is regulated by the somitic oscillator but Nrarp protein levels do not oscillate.
Results show that the Notch-regulated ankyrin repeat protein (Nrarp) acts as a molecular link between Notch- and Lef1-dependent Wnt signaling in endothelial cells to control stability of new vessel connections in mouse and zebrafish.
Title: Nrarp coordinates endothelial Notch and Wnt signaling to control vessel density in angiogenesis.
Different effects of Nrarp overexpression suggest that alternate Notch signaling pathways mediate T- versus B-cell lineage commitment and thymocyte maturation.
Title: Notch-regulated ankyrin-repeat protein inhibits Notch1 signaling: multiple Notch1 signaling pathways involved in T cell development.
The following Nrarp gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nrarp cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu16656 | |
| Clone ID Related Accession (Same CDS sequence) | NM_025980.2 | |
| Accession Version | NM_025980.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 345bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2020-01-04 | |
| Organism | Mus musculus(house mouse) | |
| Product | notch-regulated ankyrin repeat-containing protein | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY046077.1. On Jul 28, 2006 this sequence version replaced NM_025980.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: AY046077.1 [ECO:0000345] ##Evidence-Data-END## | |
1 | ATGAGCCAAG CCGAGCTGTC CACCTGCTCG GCGCCACAGA CGCAGCGCAT CTTCCAGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_080256.2 |
| CDS | 354..698 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_025980.2 |
ORF Insert Sequence:
1 | ATGAGCCAAG CCGAGCTGTC CACCTGCTCG GCGCCACAGA CGCAGCGCAT CTTCCAGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer. |
|
Carbohydrate-binding protein CLEC14A regulates VEGFR-2- and VEGFR-3-dependent signals during angiogenesis and lymphangiogenesis. |
|
Disruption of somitogenesis by a novel dominant allele of Lfng suggests important roles for protein processing and secretion. |
|
Spatiotemporal regulation of GLI target genes in the mammalian limb bud. |
|
Transcript processing and export kinetics are rate-limiting steps in expressing vertebrate segmentation clock genes. |