Cd99 cDNA ORF clone, Mus musculus(house mouse)
| Gene Symbol | Cd99 |
| Entrez Gene ID | 673094 |
| Full Name | CD99 antigen |
| Synonyms | 1110061M03Rik,2410026K10Rik,D4,Pilr-l,pilr-1 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_025584.2 | NP_079860.2 | CD99 antigen precursor |
Related articles in PubMed
Endothelial CD99 supports arrest of mouse neutrophils in venules and binds to neutrophil PILRs.
Goswami D, M?rz S, Li YT, Artz A, Sch?fer K, Seelige R, Pacheco-Blanco M, Jing D, Bixel MG, Araki M, Araki K, Yamamura KI, Vestweber D
Blood129(13)1811-1822(2017 03)
Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration.
Watson RL, Buck J, Levin LR, Winger RC, Wang J, Arase H, Muller WA
The Journal of experimental medicine212(7)1021-41(2015 Jun)
Interaction of CD99 with its paralog CD99L2 positively regulates CD99L2 trafficking to cell surfaces.
Nam G, Lee YK, Lee HY, Ma MJ, Araki M, Araki K, Lee S, Lee IS, Choi EY
Journal of immunology (Baltimore, Md. : 1950)191(11)5730-42(2013 Dec)
CD99-dependent expansion of myeloid-derived suppressor cells and attenuation of graft-versus-host disease.
Park HJ, Byun D, Lee AH, Kim JH, Ban YL, Araki M, Araki K, Yamamura K, Kim I, Park SH, Jung KC
Molecules and cells33(3)259-67(2012 Mar)
Beta1 integrin establishes endothelial cell polarity and arteriolar lumen formation via a Par3-dependent mechanism.
Zovein AC, Luque A, Turlo KA, Hofmann JJ, Yee KM, Becker MS, Fassler R, Mellman I, Lane TF, Iruela-Arispe ML
Developmental cell18(1)39-51(2010 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
endothelial CD99 promotes leukocyte attachment to endothelium in inflamed vessels by a heterophilic ligand. In addition, CD99 binds to PILRs on neutrophils, an interaction that leads to increased shear resistance of the neutrophil attachment to ICAM-1.
Title: Endothelial CD99 supports arrest of mouse neutrophils in venules and binds to neutrophil PILRs.
Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration.
Title: Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration.
role in membrane trafficking of CD99L2 and in controlling transendothelial migration of leukocytes
Title: Interaction of CD99 with its paralog CD99L2 positively regulates CD99L2 trafficking to cell surfaces.
CD99 plays a crucial role in the attenuation of graft-versus-host disease by regulating the expansion of myeloid-derived suppressor cells.
Title: CD99-dependent expansion of myeloid-derived suppressor cells and attenuation of graft-versus-host disease.
Mouse CD99 is expressed on mouse leukocytes as well as enriched at the endothelial cell borders.
Title: CD99 is essential for leukocyte diapedesis in vivo.
The following Cd99 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cd99 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu22332 | |
| Clone ID Related Accession (Same CDS sequence) | NM_025584.2 | |
| Accession Version | NM_025584.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-08-13 | |
| Organism | Mus musculus(house mouse) | |
| Product | CD99 antigen precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB122023.1. On or before Feb 15, 2007 this sequence version replaced XM_001004429.1, NM_025584.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB122023.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## | |
1 | ATGGCGCGCG CGGCGATGGA GGCGGCGGCG ACCGTGGTTT TGGCCCTGGC GCTGCTCGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_079860.2 |
| CDS | 31..558 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_025584.2 |
ORF Insert Sequence:
1 | ATGGCGCGCG CGGCGATGGA GGCGGCGGCG ACCGTGGTTT TGGCCCTGGC GCTGCTCGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
Endothelial CD99 supports arrest of mouse neutrophils in venules and binds to neutrophil PILRs. |
|
Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration. |
|
Interaction of CD99 with its paralog CD99L2 positively regulates CD99L2 trafficking to cell surfaces. |
|
CD99-dependent expansion of myeloid-derived suppressor cells and attenuation of graft-versus-host disease. |
|
Beta1 integrin establishes endothelial cell polarity and arteriolar lumen formation via a Par3-dependent mechanism. |