Gene Symbol | Bambi |
Entrez Gene ID | 68010 |
Full Name | BMP and activin membrane-bound inhibitor |
Synonyms | 2610003H06Rik |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Bambi cDNA ORF clone
gRNAs
Gene Symbol | Bambi |
Entrez Gene ID | 68010 |
Full Name | BMP and activin membrane-bound inhibitor |
Synonyms | 2610003H06Rik |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_030250585.1 | XP_030106445.1 | BMP and activin membrane-bound inhibitor homolog isoform X1 |
NM_026505.2 | NP_080781.1 | BMP and activin membrane-bound inhibitor homolog precursor |
Homo sapiens (human) | BAMBI | NP_036474.1 |
Mus musculus (house mouse) | Bambi | NP_080781.1 |
Rattus norvegicus (Norway rat) | Bambi | NP_620782.1 |
Gallus gallus (chicken) | BAMBI | NP_001182330.1 |
Xenopus tropicalis (tropical clawed frog) | bambi | NP_001008194.1 |
Danio rerio (zebrafish) | bambia | NP_571859.1 |
BAMBI | XP_001106773.2 | |
Pan troglodytes (chimpanzee) | BAMBI | XP_001150397.2 |
Canis lupus familiaris (dog) | BAMBI | XP_544209.1 |
Bos taurus (cattle) | BAMBI | NP_001039774.1 |
High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)
Foxi3 Deficiency Compromises Hair Follicle Stem Cell Specification and Activation.
Shirokova V, Biggs LC, Jussila M, Ohyama T, Groves AK, Mikkola ML
Stem cells (Dayton, Ohio)34(7)1896-908(2016 07)
BAMBI Promotes C2C12 Myogenic Differentiation by Enhancing Wnt/?-Catenin Signaling.
Zhang Q, Shi XE, Song C, Sun S, Yang G, Li X
International journal of molecular sciences16(8)17734-45(2015 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
BAMBI is required for normal C2C12 differentiation, and that its role in myogenesis is mediated by the Wnt/beta-catenin pathway.
Title: BAMBI Promotes C2C12 Myogenic Differentiation by Enhancing Wnt/?-Catenin Signaling.
BAMBI modulates the effects of diabetes on glomerular permselectivity in association with altered ERK1/2 and Smad1/5 signaling.
Title: BAMBI elimination enhances alternative TGF-? signaling and glomerular dysfunction in diabetic mice.
these results provide strong evidence for an important role of endothelium rather than platelet BAMBI as a positive regulator of both thrombus formation and stability.
Title: Vessel wall BAMBI contributes to hemostasis and thrombus stability.
suggest that BAMBI is involved in negative feedback loops that restrain the TGF-beta remodeling signals to protect the pressure-overloaded myocardium from uncontrolled extracellular matrix deposition in humans and mice
Title: BAMBI (BMP and activin membrane-bound inhibitor) protects the murine heart from pressure-overload biomechanical stress by restraining TGF-? signaling.
we provide in vitro and in vivo evidence that BAMBI contributes to endothelial and vascular homeostasis
Title: BAMBI regulates angiogenesis and endothelial homeostasis through modulation of alternative TGF? signaling.
The following Bambi gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Bambi cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu23347 | |
Clone ID Related Accession (Same CDS sequence) | XM_030250585.1 , NM_026505.2 | |
Accession Version | NM_026505.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 783bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-27 | |
Organism | Mus musculus(house mouse) | |
Product | BMP and activin membrane-bound inhibitor homolog precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC140240.2. On Nov 17, 2006 this sequence version replaced NM_026505.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK045192.1, AK143185.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGATCGCC ACTCCAGCTA CTTCTTCATC TGGCTGCAGC TGGAGCTCTG CGCCATGGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_080781.1 |
CDS | 254..1036 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGATCGCC ACTCCAGCTA CTTCTTCATC TGGCTGCAGC TGGAGCTCTG CGCCATGGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu23347 | |
Clone ID Related Accession (Same CDS sequence) | XM_030250585.1 , NM_026505.2 | |
Accession Version | XM_030250585.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 783bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | BMP and activin membrane-bound inhibitor homolog isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGATCGCC ACTCCAGCTA CTTCTTCATC TGGCTGCAGC TGGAGCTCTG CGCCATGGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030106445.1 |
CDS | 896..1678 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGATCGCC ACTCCAGCTA CTTCTTCATC TGGCTGCAGC TGGAGCTCTG CGCCATGGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
High-throughput discovery of novel developmental phenotypes. |
Foxi3 Deficiency Compromises Hair Follicle Stem Cell Specification and Activation. |
BAMBI Promotes C2C12 Myogenic Differentiation by Enhancing Wnt/?-Catenin Signaling. |