Gene Symbol | Metrn |
Entrez Gene ID | 70083 |
Full Name | meteorin, glial cell differentiation regulator |
Synonyms | 1810034B16Rik,EyeLinc16,Hyrac |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Metrn cDNA ORF clone
Gene Symbol | Metrn |
Entrez Gene ID | 70083 |
Full Name | meteorin, glial cell differentiation regulator |
Synonyms | 1810034B16Rik,EyeLinc16,Hyrac |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_133719.2 | NP_598480.1 | meteorin precursor |
Homo sapiens (human) | METRN | NP_076947.1 |
Pan troglodytes (chimpanzee) | METRN | XP_001156928.1 |
Mus musculus (house mouse) | Metrn | NP_598480.1 |
Rattus norvegicus (Norway rat) | Metrn | NP_001009962.1 |
Danio rerio (zebrafish) | metrn | NP_001009983.2 |
Gallus gallus (chicken) | METRN | XP_425223.3 |
LOC716488 | XP_001107238.1 | |
Bos taurus (cattle) | METRN | NP_001095496.1 |
Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development.
Rutledge EA, Benazet JD, McMahon AP
Development (Cambridge, England)144(17)3177-3188(2017 09)
Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia.
Heng X, Guo Q, Leung AW, Li JY
eLife6(2017 May)
Meteorin regulates mesendoderm development by enhancing nodal expression.
Kim YY, Moon JS, Kwon MC, Shin J, Im SK, Kim HA, Han JK, Kong YY
PloS one9(2)e88811(2014)
Evolutionarily conserved long intergenic non-coding RNAs in the eye.
Mustafi D, Kevany BM, Bai X, Maeda T, Sears JE, Khalil AM, Palczewski K
Human molecular genetics22(15)2992-3002(2013 Aug)
Meteorin is a chemokinetic factor in neuroblast migration and promotes stroke-induced striatal neurogenesis.
Wang Z, Andrade N, Torp M, Wattananit S, Arvidsson A, Kokaia Z, J?rgensen JR, Lindvall O
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism32(2)387-98(2012 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Meteorin is a novel regulator of Nodal transcription
Title: Meteorin regulates mesendoderm development by enhancing nodal expression.
Recombinant Metrn infused into the stroke-damaged brain stimulates cell proliferation in subventricular zone, promotes neuroblast migration, and increases the number of immature and mature neurons in the ischemic striatum.
Title: Meteorin is a chemokinetic factor in neuroblast migration and promotes stroke-induced striatal neurogenesis.
promotes both cortical stem cell differentiation and retinal glia development via Jak-STAT3 pathway
Title: Meteorin promotes the formation of GFAP-positive glia via activation of the Jak-STAT3 pathway.
Data show that Meteorin is expressed in the central nervous system both during development and in adult mice.
Title: Characterization of Meteorin--an evolutionary conserved neurotrophic factor.
The following Metrn gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Metrn cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu10131 | |
Clone ID Related Accession (Same CDS sequence) | NM_133719.2 | |
Accession Version | NM_133719.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 876bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-25 | |
Organism | Mus musculus(house mouse) | |
Product | meteorin precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK087402.1 and BF472326.1. On Dec 10, 2004 this sequence version replaced NM_133719.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK087402.1, SRR1660817.472242.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164143 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCTGGTAG CCACGCTTCT TTGCGCGCTC TGTTGCGGCC TCCTGGCCGC GTCCGCTCAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_598480.1 |
CDS | 84..959 |
Translation |
Target ORF information:
Target ORF information:
|
NM_133719.2 |
1 | ATGCTGGTAG CCACGCTTCT TTGCGCGCTC TGTTGCGGCC TCCTGGCCGC GTCCGCTCAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. |
Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia. |
Meteorin regulates mesendoderm development by enhancing nodal expression. |
Evolutionarily conserved long intergenic non-coding RNAs in the eye. |
Meteorin is a chemokinetic factor in neuroblast migration and promotes stroke-induced striatal neurogenesis. |