Gene Symbol | MBD3L1 |
Entrez Gene ID | 73503 |
Full Name | methyl-CpG binding domain protein 3-like 1 |
Synonyms | 1700070G05Rik,1700095H13Rik,Mbd3l |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(House mouse) |
Genome |
ORF » Species Summary » Mus musculus » MBD3L1 cDNA ORF clone
Gene Symbol | MBD3L1 |
Entrez Gene ID | 73503 |
Full Name | methyl-CpG binding domain protein 3-like 1 |
Synonyms | 1700070G05Rik,1700095H13Rik,Mbd3l |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(House mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001357419.1 | NP_001344348.1 | methyl-CpG-binding domain protein 3-like 1 |
XM_006510640.2 | XP_006510703.1 | methyl-CpG-binding domain protein 3-like 1 isoform X1 |
NM_001357418.1 | NP_001344347.1 | methyl-CpG-binding domain protein 3-like 1 |
NM_028557.3 | NP_082833.1 | methyl-CpG-binding domain protein 3-like 1 |
XM_006510639.1 | XP_006510702.1 | methyl-CpG-binding domain protein 3-like 1 isoform X1 |
NM_028557.2 | NP_082833.1 | methyl-CpG-binding domain protein 3-like 1 |
Homo sapiens (human) | MBD3L1 | NP_660209.2 |
Pan troglodytes (chimpanzee) | MBD3L1 | XP_003316115.1 |
MBD3L1 | XP_001095444.1 | |
Canis lupus familiaris (dog) | MBD3L1 | XP_003432911.1 |
Bos taurus (cattle) | MBD3L1 | NP_001070554.1 |
Mus musculus (house mouse) | Mbd3l1 | NP_082833.1 |
Rattus norvegicus (Norway rat) | Mbd3l1 | NP_001100273.1 |
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H
Developmental cell17(6)836-48(2009 Dec)
Haploid male germ cell- and oocyte-specific Mbd3l1 and Mbd3l2 genes are dispensable for early development, fertility, and zygotic DNA demethylation in the mouse.
Jin SG, Tsark W, Szab? PE, Pfeifer GP
Developmental dynamics : an official publication of the American Association of Anatomists237(11)3435-43(2008 Nov)
MBD3L1 is a transcriptional repressor that interacts with methyl-CpG-binding protein 2 (MBD2) and components of the NuRD complex.
Jiang CL, Jin SG, Pfeifer GP
The Journal of biological chemistry279(50)52456-64(2004 Dec)
MBD3L1 and MBD3L2, two new proteins homologous to the methyl-CpG-binding proteins MBD2 and MBD3: characterization of MBD3L1 as a testis-specific transcriptional repressor.
Jiang CL, Jin SG, Lee DH, Lan ZJ, Xu X, O'Connor TR, Szab? PE, Mann JR, Cooney AJ, Pfeifer GP
Genomics80(6)621-9(2002 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Mbd3l1 and Mbd3l2 are not involved in genome-wide demethylation of paternal genomes in mouse zygotes and are dispensable for normal development.
Title: Haploid male germ cell- and oocyte-specific Mbd3l1 and Mbd3l2 genes are dispensable for early development, fertility, and zygotic DNA demethylation in the mouse.
interacts with methyl-CpG-binding protein 2 (MBD2) and components of the NuRD complex
Title: MBD3L1 is a transcriptional repressor that interacts with methyl-CpG-binding protein 2 (MBD2) and components of the NuRD complex.
The following MBD3L1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MBD3L1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu05803 | |
Clone ID Related Accession (Same CDS sequence) | NM_001357419.1 , XM_006510640.2 , NM_001357418.1 , NM_028557.3 , XM_006510639.1 , NM_028557.2 | |
Accession Version | NM_001357419.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 561bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-29 | |
Organism | Mus musculus(house mouse) | |
Product | methyl-CpG-binding domain protein 3-like 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC162941.5. On Oct 27, 2017 this sequence version replaced XM_006510640.2. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All three variants encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: CN832321.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849384 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGGCAAGA CTTCACAGAG GAAACAATGT GACTGTGAAA ACCCATCAAA GCCTTGTTTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001344348.1 |
CDS | 94..654 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001357419.1 |
1 | ATGGGCAAGA CTTCACAGAG GAAACAATGT GACTGTGAAA ACCCATCAAA GCCTTGTTTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu05803 | |
Clone ID Related Accession (Same CDS sequence) | NM_001357419.1 , XM_006510640.2 , NM_001357418.1 , NM_028557.3 , XM_006510639.1 , NM_028557.2 | |
Accession Version | NM_001357418.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 561bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-28 | |
Organism | Mus musculus(house mouse) | |
Product | methyl-CpG-binding domain protein 3-like 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK018931.1, AC162941.5 and BC049738.1. On Oct 27, 2017 this sequence version replaced XM_006510639.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All three variants encode the same protein. ##Evidence-Data-START## Transcript exon combination :: AK018931.1, BY707155.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849384 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGGCAAGA CTTCACAGAG GAAACAATGT GACTGTGAAA ACCCATCAAA GCCTTGTTTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001344347.1 |
CDS | 112..672 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001357418.1 |
1 | ATGGGCAAGA CTTCACAGAG GAAACAATGT GACTGTGAAA ACCCATCAAA GCCTTGTTTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu05803 | |
Clone ID Related Accession (Same CDS sequence) | NM_001357419.1 , XM_006510640.2 , NM_001357418.1 , NM_028557.3 , XM_006510639.1 , NM_028557.2 | |
Accession Version | NM_028557.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 561bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-28 | |
Organism | Mus musculus(house mouse) | |
Product | methyl-CpG-binding domain protein 3-like 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC162941.5, AK006927.1 and BC049738.1. On Oct 27, 2017 this sequence version replaced NM_028557.2. Transcript Variant: This variant (1) represents the longest transcript. All three variants encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC049738.1, BC061034.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849384 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGGCAAGA CTTCACAGAG GAAACAATGT GACTGTGAAA ACCCATCAAA GCCTTGTTTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_082833.1 |
CDS | 153..713 |
Translation |
Target ORF information:
Target ORF information:
|
NM_028557.3 |
1 | ATGGGCAAGA CTTCACAGAG GAAACAATGT GACTGTGAAA ACCCATCAAA GCCTTGTTTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu05803 | |
Clone ID Related Accession (Same CDS sequence) | NM_001357419.1 , XM_006510640.2 , NM_001357418.1 , NM_028557.3 , XM_006510639.1 , NM_028557.2 | |
Accession Version | NM_028557.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 561bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-04-28 | |
Organism | Mus musculus(House mouse) | |
Product | methyl-CpG-binding domain protein 3-like 1 | |
Comment | PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK006927.1. On Apr 6, 2007 this sequence version replaced NM_028557.1. ##Evidence-Data-START## Transcript exon combination :: BC061034.1, AK006927.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849384 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGGCAAGA CTTCACAGAG GAAACAATGT GACTGTGAAA ACCCATCAAA GCCTTGTTTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_082833.1 |
CDS | 117..677 |
Translation |
Target ORF information:
Target ORF information:
|
NM_028557.2 |
1 | ATGGGCAAGA CTTCACAGAG GAAACAATGT GACTGTGAAA ACCCATCAAA GCCTTGTTTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu05803 | |
Clone ID Related Accession (Same CDS sequence) | NM_001357419.1 , XM_006510640.2 , NM_001357418.1 , NM_028557.3 , XM_006510639.1 , NM_028557.2 | |
Accession Version | XM_006510640.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 561bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(House mouse) | |
Product | methyl-CpG-binding domain protein 3-like 1 isoform X1 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006510640.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGCAAGA CTTCACAGAG GAAACAATGT GACTGTGAAA ACCCATCAAA GCCTTGTTTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006510703.1 |
CDS | 74..634 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006510640.2 |
1 | ATGGGCAAGA CTTCACAGAG GAAACAATGT GACTGTGAAA ACCCATCAAA GCCTTGTTTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu05803 | |
Clone ID Related Accession (Same CDS sequence) | NM_001357419.1 , XM_006510640.2 , NM_001357418.1 , NM_028557.3 , XM_006510639.1 , NM_028557.2 | |
Accession Version | XM_006510639.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 561bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(House mouse) | |
Product | methyl-CpG-binding domain protein 3-like 1 isoform X1 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGCAAGA CTTCACAGAG GAAACAATGT GACTGTGAAA ACCCATCAAA GCCTTGTTTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006510702.1 |
CDS | 141..701 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006510639.1 |
1 | ATGGGCAAGA CTTCACAGAG GAAACAATGT GACTGTGAAA ACCCATCAAA GCCTTGTTTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. |
Haploid male germ cell- and oocyte-specific Mbd3l1 and Mbd3l2 genes are dispensable for early development, fertility, and zygotic DNA demethylation in the mouse. |
MBD3L1 is a transcriptional repressor that interacts with methyl-CpG-binding protein 2 (MBD2) and components of the NuRD complex. |
MBD3L1 and MBD3L2, two new proteins homologous to the methyl-CpG-binding proteins MBD2 and MBD3: characterization of MBD3L1 as a testis-specific transcriptional repressor. |