Gene Symbol | Wipi2 |
Entrez Gene ID | 74781 |
Full Name | WD repeat domain, phosphoinositide interacting 2 |
Synonyms | 1110018O08Rik,2510001I10Rik |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Wipi2 cDNA ORF clone
Gene Symbol | Wipi2 |
Entrez Gene ID | 74781 |
Full Name | WD repeat domain, phosphoinositide interacting 2 |
Synonyms | 1110018O08Rik,2510001I10Rik |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006504752.4 | XP_006504815.1 | WD repeat domain phosphoinositide-interacting protein 2 isoform X1 |
XM_006504752.3 | XP_006504815.1 | WD repeat domain phosphoinositide-interacting protein 2 isoform X1 |
NM_178398.4 | NP_848485.1 | WD repeat domain phosphoinositide-interacting protein 2 |
Canis lupus familiaris (dog) | WIPI2 | XP_850630.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP005910 | XP_315940.3 |
Eremothecium gossypii | AGOS_AAL119W | NP_982423.1 |
Pan troglodytes (chimpanzee) | WIPI2 | XP_003318335.1 |
Bos taurus (cattle) | WIPI2 | NP_001039594.1 |
Drosophila melanogaster (fruit fly) | Atg18 | NP_001261565.1 |
Kluyveromyces lactis | KLLA0D04664g | XP_453268.1 |
Schizosaccharomyces pombe (fission yeast) | atg18 | NP_594055.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_03139 | XP_003716858.1 |
Mus musculus (house mouse) | Wipi2 | NP_848485.1 |
Rattus norvegicus (Norway rat) | Wipi2 | NP_001007616.1 |
Gallus gallus (chicken) | WIPI2 | NP_001006162.1 |
Neurospora crassa | NCU03441 | XP_956727.1 |
Oryza sativa (rice) | Os02g0791800 | NP_001048361.1 |
Homo sapiens (human) | WIPI2 | NP_057087.2 |
Saccharomyces cerevisiae (baker's yeast) | ATG18 | NP_444297.1 |
Arabidopsis thaliana (thale cress) | G18B | NP_194780.2 |
Xenopus tropicalis (tropical clawed frog) | LOC100497399 | XP_004917971.1 |
Caenorhabditis elegans (roundworm) | atg-18 | NP_741576.1 |
Optineurin promotes autophagosome formation by recruiting the autophagy-related Atg12-5-16L1 complex to phagophores containing the Wipi2 protein.
Bansal M, Moharir SC, Sailasree SP, Sirohi K, Sudhakar C, Sarathi DP, Lakshmi BJ, Buono M, Kumar S, Swarup G
The Journal of biological chemistry293(1)132-147(2018 Jan)
Constitutive Autophagy and Nucleophagy during Epidermal Differentiation.
Akinduro O, Sully K, Patel A, Robinson DJ, Chikh A, McPhail G, Braun KM, Philpott MP, Harwood CA, Byrne C, O'Shaughnessy RFL, Bergamaschi D
The Journal of investigative dermatology136(7)1460-1470(2016 Jul)
WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1.
Dooley HC, Razi M, Polson HE, Girardin SE, Wilson MI, Tooze SA
Molecular cell55(2)238-52(2014 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Wipi2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Wipi2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu07307 | |
Clone ID Related Accession (Same CDS sequence) | NM_178398.4 | |
Accession Version | NM_178398.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1338bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-24 | |
Organism | Mus musculus(house mouse) | |
Product | WD repeat domain phosphoinositide-interacting protein 2 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC158310.3 and AC105987.21. On May 2, 2007 this sequence version replaced NM_178398.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660817.112078.1, AK155113.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAACCTGG CGAGCCAGAG CGGAGAGGCC GGCGCCGGCC AGCTGCTGTT CGCCAACTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_848485.1 |
CDS | 176..1513 |
Translation |
Target ORF information:
Target ORF information:
|
NM_178398.4 |
1 | ATGAACCTGG CGAGCCAGAG CGGAGAGGCC GGCGCCGGCC AGCTGCTGTT CGCCAACTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu36347 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504752.4 , XM_006504752.3 | |
Accession Version | XM_006504752.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 960bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | WD repeat domain phosphoinositide-interacting protein 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006504752.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAAGGTAC TTCATACCAT CCGAGAGACA CCCCCAAACC CTGCAGGCTT GTGTGCACTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006504815.1 |
CDS | 520..1479 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006504752.3 |
1 | ATGAAGGTAC TTCATACCAT CCGAGAGACA CCCCCAAACC CTGCAGGCTT GTGTGCACTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu36347 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504752.4 , XM_006504752.3 | |
Accession Version | XM_006504752.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 960bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | WD repeat domain phosphoinositide-interacting protein 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006504752.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAAGGTAC TTCATACCAT CCGAGAGACA CCCCCAAACC CTGCAGGCTT GTGTGCACTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006504815.1 |
CDS | 522..1481 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006504752.4 |
1 | ATGAAGGTAC TTCATACCAT CCGAGAGACA CCCCCAAACC CTGCAGGCTT GTGTGCACTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Optineurin promotes autophagosome formation by recruiting the autophagy-related Atg12-5-16L1 complex to phagophores containing the Wipi2 protein. |
Constitutive Autophagy and Nucleophagy during Epidermal Differentiation. |
WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1. |