Gene Symbol | S1pr5 |
Entrez Gene ID | 94226 |
Full Name | sphingosine-1-phosphate receptor 5 |
Synonyms | Edg8,S1P5,lpB4 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » S1pr5 cDNA ORF clone
Gene Symbol | S1pr5 |
Entrez Gene ID | 94226 |
Full Name | sphingosine-1-phosphate receptor 5 |
Synonyms | Edg8,S1P5,lpB4 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_053190.2 | NP_444420.1 | sphingosine 1-phosphate receptor 5 |
Pan troglodytes (chimpanzee) | S1PR5 | XP_003316134.1 |
Bos taurus (cattle) | S1PR5 | NP_001179404.1 |
S1PR5 | XP_001101585.2 | |
Canis lupus familiaris (dog) | S1PR5 | XP_005632952.1 |
Mus musculus (house mouse) | S1pr5 | NP_444420.1 |
Danio rerio (zebrafish) | s1pr5b | NP_001073124.1 |
Homo sapiens (human) | S1PR5 | NP_001159687.1 |
Rattus norvegicus (Norway rat) | S1pr5 | NP_068543.2 |
Sphingosine 1-phosphate signaling through its receptor S1P
Andrieu G, Ledoux A, Branka S, Bocquet M, Gilhodes J, Walzer T, Kasahara K, Inagaki M, Sabbadini RA, Cuvillier O, Hatzoglou A
Science signaling10(472)(2017 Mar)
Gradients of the signaling lipid S1P in lymph nodes position natural killer cells and regulate their interferon-? response.
Fang V, Chaluvadi VS, Ramos-Perez WD, Mendoza A, Baeyens A, Rivera R, Chun J, Cammer M, Schwab SR
Nature immunology18(1)15-25(2017 Jan)
Tcf4 Regulates Synaptic Plasticity, DNA Methylation, and Memory Function.
Kennedy AJ, Rahn EJ, Paulukaitis BS, Savell KE, Kordasiewicz HB, Wang J, Lewis JW, Posey J, Strange SK, Guzman-Karlsson MC, Phillips SE, Decker K, Motley ST, Swayze EE, Ecker DJ, Michael TP, Day JJ, Sweatt JD
Cell reports16(10)2666-2685(2016 09)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
reduced frequency of patrolling monocytes in bone marrow of KO mice
Title: S1PR5 is pivotal for the homeostasis of patrolling monocytes.
Coordinated changes in CXCR4 and S1P5 responsiveness govern NK-cell trafficking.
Title: Sequential desensitization of CXCR4 and S1P5 controls natural killer cell trafficking.
Fndings suggest that S1P(5) may mediate the effects of S1P in terms of regulating ERK-1/2 signaling in ES cells.
Title: Sphingosine 1-phosphate regulation of extracellular signal-regulated kinase-1/2 in embryonic stem cells.
These findings identify S1P5 as a T-bet-induced gene that is required for natural killer cell egress from lymph nodes and bone marrow.
Title: T-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow.
KLF2 regulates T cell homeostasis at least partly by controlling CD62L and S1P1 expression, and therefore T cell egress from the thymus and circulation in the periphery.
Title: Kruppel-like factor 2 controls T cell trafficking by activating L-selectin (CD62L) and sphingosine-1-phosphate receptor 1 transcription.
The following S1pr5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the S1pr5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu09329 | |
Clone ID Related Accession (Same CDS sequence) | NM_053190.2 | |
Accession Version | NM_053190.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1203bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-23 | |
Organism | Mus musculus(house mouse) | |
Product | sphingosine 1-phosphate receptor 5 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY736639.1, AK081126.1, AI848371.1 and AI852113.1. On Nov 15, 2007 this sequence version replaced NM_053190.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BY736639.1, BI329992.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGAGCCCG GGCTGCTGCG GCCGGCGCCG GTGAGTGAGG TTATTGTCCT TCACTACAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_444420.1 |
CDS | 284..1486 |
Translation |
Target ORF information:
Target ORF information:
|
NM_053190.2 |
1 | ATGGAGCCCG GGCTGCTGCG GCCGGCGCCG GTGAGTGAGG TTATTGTCCT TCACTACAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Sphingosine 1-phosphate signaling through its receptor S1P |
Gradients of the signaling lipid S1P in lymph nodes position natural killer cells and regulate their interferon-? response. |
Tcf4 Regulates Synaptic Plasticity, DNA Methylation, and Memory Function. |