Gene Symbol | BPI |
Entrez Gene ID | 100009228 |
Full Name | bactericidal/permeability-increasing protein |
Gene Type | protein-coding |
Organism | Oryctolagus cuniculus(rabbit) |
ORF » Species Summary » Oryctolagus cuniculus » BPI cDNA ORF clone
Gene Symbol | BPI |
Entrez Gene ID | 100009228 |
Full Name | bactericidal/permeability-increasing protein |
Gene Type | protein-coding |
Organism | Oryctolagus cuniculus(rabbit) |
mRNA | Protein | Name |
---|---|---|
NM_001195804.1 | NP_001182733.1 | bactericidal permeability-increasing protein precursor |
Host defense functions of proteolytically processed and parent (unprocessed) cathelicidins of rabbit granulocytes.
Zarember KA, Katz SS, Tack BF, Doukhan L, Weiss J, Elsbach P
Infection and immunity70(2)569-76(2002 Feb)
p15s (15-kD antimicrobial proteins) are stored in the secondary granules of Rabbit granulocytes: implications for antibacterial synergy with the bactericidal/permeability-increasing protein in inflammatory fluids.
Zarember K, Elsbach P, Shin-Kim K, Weiss J
Blood89(2)672-9(1997 Jan)
Cloning of the cDNA of a human neutrophil bactericidal protein. Structural and functional correlations.
Gray PW, Flaggs G, Leong SR, Gumina RJ, Weiss J, Ooi CE, Elsbach P
The Journal of biological chemistry264(16)9505-9(1989 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The p15 proteins exhibit antimicrobial synergy with another rabbit cathelicidin (CAP-18) and with the rabbit Bactericidal/permeability-increasing protein (BPI).
Title: Host defense functions of proteolytically processed and parent (unprocessed) cathelicidins of rabbit granulocytes.
p15 proteins are stored in the specific (secondary) granules of rabbit neutrophils and are secreted extracellularly after inflammatory stimulation.
Title: p15s (15-kD antimicrobial proteins) are stored in the secondary granules of Rabbit granulocytes: implications for antibacterial synergy with the bactericidal/permeability-increasing protein in inflammatory fluids.
The following BPI gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BPI cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OOb00232 | |
Clone ID Related Accession (Same CDS sequence) | NM_001195804.1 | |
Accession Version | NM_001195804.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1449bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-21 | |
Organism | Oryctolagus cuniculus(rabbit) | |
Product | bactericidal permeability-increasing protein precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AAGW02060090.1 and AAGW02060089.1. On Sep 30, 2010 this sequence version replaced XM_002710811.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: GBCI01163738.1, GBCK01144763.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1876818, SAMEA1876819 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGCCAGGG GTCCTGAGGG CGTGCGGAGC TGGCCAGCCC TGGTGCTGCT GGCCGCCGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001182733.1 |
CDS | 1..1449 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGGCCAGGG GTCCTGAGGG CGTGCGGAGC TGGCCAGCCC TGGTGCTGCT GGCCGCCGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Host defense functions of proteolytically processed and parent (unprocessed) cathelicidins of rabbit granulocytes. |
p15s (15-kD antimicrobial proteins) are stored in the secondary granules of Rabbit granulocytes: implications for antibacterial synergy with the bactericidal/permeability-increasing protein in inflammatory fluids. |
Cloning of the cDNA of a human neutrophil bactericidal protein. Structural and functional correlations. |