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C1qc cDNA ORF clone, Mus musculus(house mouse)

Summary

Gene Symbol C1qc
Entrez Gene ID 12262
Full Name complement component 1, q subcomponent, C chain
Synonyms AI385742,C1qg,Ciqc
General protein information
Preferred Names

complement component 1, q subcomponent, C chain

Names

complement C1q subcomponent subunit C
complement component 1, q subcomponent, c polypeptide
complement component 1, q subcomponent, gamma polypeptide
Gene Type protein-coding
Organism Mus musculus(house mouse)
Genome

4

4 D3|4 69.05 cM

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_017319927.1 XP_017175416.1 complement C1q subcomponent subunit C isoform X1
NM_007574.2 NP_031600.2 complement C1q subcomponent subunit C precursor
XM_017319927.2 XP_017175416.1 complement C1q subcomponent subunit C isoform X1

Pathways from BioSystems


Homologies


C1QC XP_001102196.1
Gallus gallus (chicken) C1QC XP_417653.1
Pan troglodytes (chimpanzee) C1QC XP_003307908.1
Rattus norvegicus (Norway rat) C1qc NP_001008524.1
Homo sapiens (human) C1QC NP_758957.2
Canis lupus familiaris (dog) C1QC XP_003433793.1
Bos taurus (cattle) C1QC NP_001193325.1
Danio rerio (zebrafish) c1qc NP_001005976.1
Mus musculus (house mouse) C1qc NP_031600.2

Gene Ontology


Bibliography

Related articles in PubMed

Complement and microglia mediate early synapse loss in Alzheimer mouse models.
Hong S, Beja-Glasser VF, Nfonoyim BM, Frouin A, Li S, Ramakrishnan S, Merry KM, Shi Q, Rosenthal A, Barres BA, Lemere CA, Selkoe DJ, Stevens B
Science (New York, N.Y.)352(6286)712-716(2016 May)

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.
Miller JA, Nathanson J, Franjic D, Shim S, Dalley RA, Shapouri S, Smith KA, Sunkin SM, Bernard A, Bennett JL, Lee CK, Hawrylycz MJ, Jones AR, Amaral DG, ?estan N, Gage FH, Lein ES
Development (Cambridge, England)140(22)4633-44(2013 Nov)

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Abonnenc M, Nabeebaccus AA, Mayr U, Barallobre-Barreiro J, Dong X, Cuello F, Sur S, Drozdov I, Langley SR, Lu R, Stathopoulou K, Didangelos A, Yin X, Zimmermann WH, Shah AM, Zampetaki A, Mayr M
Circulation research113(10)1138-47(2013 Oct)

Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.
Lumayag S, Haldin CE, Corbett NJ, Wahlin KJ, Cowan C, Turturro S, Larsen PE, Kovacs B, Witmer PD, Valle D, Zack DJ, Nicholson DA, Xu S
Proceedings of the National Academy of Sciences of the United States of America110(6)E507-16(2013 Feb)

Molecular mechanisms for synchronized transcription of three complement C1q subunit genes in dendritic cells and macrophages.
Chen G, Tan CS, Teh BK, Lu J
The Journal of biological chemistry286(40)34941-50(2011 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

analysis of the molecular mechanisms for synchronized transcription of three complement C1q subunit genes (A, B and C) in dendritic cells and macrophages
Title: Molecular mechanisms for synchronized transcription of three complement C1q subunit genes in dendritic cells and macrophages.

The following C1qc gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the C1qc cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OMu00398 NM_007574.2
Latest version!		 Mus musculus complement component 1, q subcomponent, C chain (C1qc), mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $139.30
$199.00
OMu00398 XM_017319927.2
Latest version!		 Mus musculus complement component 1, q subcomponent, C chain (C1qc), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $139.30
$199.00
View Old Accession Versions >>
OMu00398 XM_017319927.1 Mus musculus complement component 1, q subcomponent, C chain (C1qc), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $139.30
$199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OMu00398
Clone ID Related Accession (Same CDS sequence) XM_017319927.1 , NM_007574.2 , XM_017319927.2
Accession Version NM_007574.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 741bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-25
Organism Mus musculus(house mouse)
Product complement C1q subcomponent subunit C precursor
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB636871.1, CK332232.1 and AI385742.1. On Aug 31, 2006 this sequence version replaced NM_007574.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC043945.1, X66295.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGGTCGTTG GACCCAGTTG CCAGCCTCCA TGTGGACTTT GCCTGCTGCT GCTGTTTCTT 
CTGGCCCTAC CACTCAGGAG CCAGGCCAGC GCTGGCTGCT ATGGGATCCC AGGGATGCCA 
GGCATGCCGG GGGCCCCTGG GAAGGACGGG CATGATGGAC TCCAGGGGCC CAAGGGAGAG 
CCAGGAATCC CAGCCGTCCC TGGGACCCGA GGACCCAAGG GTCAGAAGGG CGAGCCTGGC 
ATGCCTGGCC ACCGTGGGAA AAATGGCCCC AGGGGGACCT CAGGGTTGCC AGGGGACCCA 
GGCCCCAGGG GGCCTCCGGG GGAGCCAGGT GTGGAGGGCC GATACAAACA GAAGCACCAG 
TCGGTATTCA CAGTCACCCG GCAGACCACC CAGTACCCAG AGGCCAACGC CCTCGTCAGG 
TTCAACTCTG TGGTCACCAA CCCTCAGGGG CATTACAACC CAAGCACAGG GAAGTTCACC 
TGTGAAGTGC CGGGCCTCTA CTACTTCGTC TACTACACAT CGCATACGGC CAACCTGTGC 
GTGCACCTGA ACCTCAACCT TGCCAGGGTG GCCAGCTTCT GCGACCACAT GTTCAACAGC 
AAGCAGGTCA GCTCCGGAGG AGTCCTCCTG CGGCTCCAGA GGGGCGATGA GGTGTGGCTA 
TCAGTCAATG ACTACAATGG CATGGTGGGC ATAGAGGGCT CCAACAGCGT CTTCTCTGGT 
TTCCTACTGT TTCCCGACTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_031600.2
CDS73..813
Translation

Target ORF information:

RefSeq Version NM_007574.2
Organism Mus musculus(house mouse)
Definition Mus musculus complement component 1, q subcomponent, C chain (C1qc), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_007574.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGGTCGTTG GACCCAGTTG CCAGCCTCCA TGTGGACTTT GCCTGCTGCT GCTGTTTCTT 
CTGGCCCTAC CACTCAGGAG CCAGGCCAGC GCTGGCTGCT ATGGGATCCC AGGGATGCCA 
GGCATGCCGG GGGCCCCTGG GAAGGACGGG CATGATGGAC TCCAGGGGCC CAAGGGAGAG 
CCAGGAATCC CAGCCGTCCC TGGGACCCGA GGACCCAAGG GTCAGAAGGG CGAGCCTGGC 
ATGCCTGGCC ACCGTGGGAA AAATGGCCCC AGGGGGACCT CAGGGTTGCC AGGGGACCCA 
GGCCCCAGGG GGCCTCCGGG GGAGCCAGGT GTGGAGGGCC GATACAAACA GAAGCACCAG 
TCGGTATTCA CAGTCACCCG GCAGACCACC CAGTACCCAG AGGCCAACGC CCTCGTCAGG 
TTCAACTCTG TGGTCACCAA CCCTCAGGGG CATTACAACC CAAGCACAGG GAAGTTCACC 
TGTGAAGTGC CGGGCCTCTA CTACTTCGTC TACTACACAT CGCATACGGC CAACCTGTGC 
GTGCACCTGA ACCTCAACCT TGCCAGGGTG GCCAGCTTCT GCGACCACAT GTTCAACAGC 
AAGCAGGTCA GCTCCGGAGG AGTCCTCCTG CGGCTCCAGA GGGGCGATGA GGTGTGGCTA 
TCAGTCAATG ACTACAATGG CATGGTGGGC ATAGAGGGCT CCAACAGCGT CTTCTCTGGT 
TTCCTACTGT TTCCCGACTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu00398
Clone ID Related Accession (Same CDS sequence) XM_017319927.1 , NM_007574.2 , XM_017319927.2
Accession Version XM_017319927.1 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 741bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-21
Organism Mus musculus(house mouse)
Product complement C1q subcomponent subunit C isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGGTCGTTG GACCCAGTTG CCAGCCTCCA TGTGGACTTT GCCTGCTGCT GCTGTTTCTT 
CTGGCCCTAC CACTCAGGAG CCAGGCCAGC GCTGGCTGCT ATGGGATCCC AGGGATGCCA 
GGCATGCCGG GGGCCCCTGG GAAGGACGGG CATGATGGAC TCCAGGGGCC CAAGGGAGAG 
CCAGGAATCC CAGCCGTCCC TGGGACCCGA GGACCCAAGG GTCAGAAGGG CGAGCCTGGC 
ATGCCTGGCC ACCGTGGGAA AAATGGCCCC AGGGGGACCT CAGGGTTGCC AGGGGACCCA 
GGCCCCAGGG GGCCTCCGGG GGAGCCAGGT GTGGAGGGCC GATACAAACA GAAGCACCAG 
TCGGTATTCA CAGTCACCCG GCAGACCACC CAGTACCCAG AGGCCAACGC CCTCGTCAGG 
TTCAACTCTG TGGTCACCAA CCCTCAGGGG CATTACAACC CAAGCACAGG GAAGTTCACC 
TGTGAAGTGC CGGGCCTCTA CTACTTCGTC TACTACACAT CGCATACGGC CAACCTGTGC 
GTGCACCTGA ACCTCAACCT TGCCAGGGTG GCCAGCTTCT GCGACCACAT GTTCAACAGC 
AAGCAGGTCA GCTCCGGAGG AGTCCTCCTG CGGCTCCAGA GGGGCGATGA GGTGTGGCTA 
TCAGTCAATG ACTACAATGG CATGGTGGGC ATAGAGGGCT CCAACAGCGT CTTCTCTGGT 
TTCCTACTGT TTCCCGACTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_017175416.1
CDS141..881
Translation

Target ORF information:

RefSeq Version XM_017319927.1
Organism Mus musculus(house mouse)
Definition Mus musculus complement component 1, q subcomponent, C chain (C1qc), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017319927.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGGTCGTTG GACCCAGTTG CCAGCCTCCA TGTGGACTTT GCCTGCTGCT GCTGTTTCTT 
CTGGCCCTAC CACTCAGGAG CCAGGCCAGC GCTGGCTGCT ATGGGATCCC AGGGATGCCA 
GGCATGCCGG GGGCCCCTGG GAAGGACGGG CATGATGGAC TCCAGGGGCC CAAGGGAGAG 
CCAGGAATCC CAGCCGTCCC TGGGACCCGA GGACCCAAGG GTCAGAAGGG CGAGCCTGGC 
ATGCCTGGCC ACCGTGGGAA AAATGGCCCC AGGGGGACCT CAGGGTTGCC AGGGGACCCA 
GGCCCCAGGG GGCCTCCGGG GGAGCCAGGT GTGGAGGGCC GATACAAACA GAAGCACCAG 
TCGGTATTCA CAGTCACCCG GCAGACCACC CAGTACCCAG AGGCCAACGC CCTCGTCAGG 
TTCAACTCTG TGGTCACCAA CCCTCAGGGG CATTACAACC CAAGCACAGG GAAGTTCACC 
TGTGAAGTGC CGGGCCTCTA CTACTTCGTC TACTACACAT CGCATACGGC CAACCTGTGC 
GTGCACCTGA ACCTCAACCT TGCCAGGGTG GCCAGCTTCT GCGACCACAT GTTCAACAGC 
AAGCAGGTCA GCTCCGGAGG AGTCCTCCTG CGGCTCCAGA GGGGCGATGA GGTGTGGCTA 
TCAGTCAATG ACTACAATGG CATGGTGGGC ATAGAGGGCT CCAACAGCGT CTTCTCTGGT 
TTCCTACTGT TTCCCGACTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu00398
Clone ID Related Accession (Same CDS sequence) XM_017319927.1 , NM_007574.2 , XM_017319927.2
Accession Version XM_017319927.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 741bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-07
Organism Mus musculus(house mouse)
Product complement C1q subcomponent subunit C isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_017319927.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGGTCGTTG GACCCAGTTG CCAGCCTCCA TGTGGACTTT GCCTGCTGCT GCTGTTTCTT 
CTGGCCCTAC CACTCAGGAG CCAGGCCAGC GCTGGCTGCT ATGGGATCCC AGGGATGCCA 
GGCATGCCGG GGGCCCCTGG GAAGGACGGG CATGATGGAC TCCAGGGGCC CAAGGGAGAG 
CCAGGAATCC CAGCCGTCCC TGGGACCCGA GGACCCAAGG GTCAGAAGGG CGAGCCTGGC 
ATGCCTGGCC ACCGTGGGAA AAATGGCCCC AGGGGGACCT CAGGGTTGCC AGGGGACCCA 
GGCCCCAGGG GGCCTCCGGG GGAGCCAGGT GTGGAGGGCC GATACAAACA GAAGCACCAG 
TCGGTATTCA CAGTCACCCG GCAGACCACC CAGTACCCAG AGGCCAACGC CCTCGTCAGG 
TTCAACTCTG TGGTCACCAA CCCTCAGGGG CATTACAACC CAAGCACAGG GAAGTTCACC 
TGTGAAGTGC CGGGCCTCTA CTACTTCGTC TACTACACAT CGCATACGGC CAACCTGTGC 
GTGCACCTGA ACCTCAACCT TGCCAGGGTG GCCAGCTTCT GCGACCACAT GTTCAACAGC 
AAGCAGGTCA GCTCCGGAGG AGTCCTCCTG CGGCTCCAGA GGGGCGATGA GGTGTGGCTA 
TCAGTCAATG ACTACAATGG CATGGTGGGC ATAGAGGGCT CCAACAGCGT CTTCTCTGGT 
TTCCTACTGT TTCCCGACTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_017175416.1
CDS145..885
Translation

Target ORF information:

RefSeq Version XM_017319927.2
Organism Mus musculus(house mouse)
Definition Mus musculus complement component 1, q subcomponent, C chain (C1qc), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017319927.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGGTCGTTG GACCCAGTTG CCAGCCTCCA TGTGGACTTT GCCTGCTGCT GCTGTTTCTT 
CTGGCCCTAC CACTCAGGAG CCAGGCCAGC GCTGGCTGCT ATGGGATCCC AGGGATGCCA 
GGCATGCCGG GGGCCCCTGG GAAGGACGGG CATGATGGAC TCCAGGGGCC CAAGGGAGAG 
CCAGGAATCC CAGCCGTCCC TGGGACCCGA GGACCCAAGG GTCAGAAGGG CGAGCCTGGC 
ATGCCTGGCC ACCGTGGGAA AAATGGCCCC AGGGGGACCT CAGGGTTGCC AGGGGACCCA 
GGCCCCAGGG GGCCTCCGGG GGAGCCAGGT GTGGAGGGCC GATACAAACA GAAGCACCAG 
TCGGTATTCA CAGTCACCCG GCAGACCACC CAGTACCCAG AGGCCAACGC CCTCGTCAGG 
TTCAACTCTG TGGTCACCAA CCCTCAGGGG CATTACAACC CAAGCACAGG GAAGTTCACC 
TGTGAAGTGC CGGGCCTCTA CTACTTCGTC TACTACACAT CGCATACGGC CAACCTGTGC 
GTGCACCTGA ACCTCAACCT TGCCAGGGTG GCCAGCTTCT GCGACCACAT GTTCAACAGC 
AAGCAGGTCA GCTCCGGAGG AGTCCTCCTG CGGCTCCAGA GGGGCGATGA GGTGTGGCTA 
TCAGTCAATG ACTACAATGG CATGGTGGGC ATAGAGGGCT CCAACAGCGT CTTCTCTGGT 
TTCCTACTGT TTCCCGACTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Complement and microglia mediate early synapse loss in Alzheimer mouse models.
Science (New York, N.Y.)352(6286)712-716(2016 May)
Hong S,Beja-Glasser VF,Nfonoyim BM,Frouin A,Li S,Ramakrishnan S,Merry KM,Shi Q,Rosenthal A,Barres BA,Lemere CA,Selkoe DJ,Stevens B


book

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.
Development (Cambridge, England)140(22)4633-44(2013 Nov)
Miller JA,Nathanson J,Franjic D,Shim S,Dalley RA,Shapouri S,Smith KA,Sunkin SM,Bernard A,Bennett JL,Lee CK,Hawrylycz MJ,Jones AR,Amaral DG,?estan N,Gage FH,Lein ES


book

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Circulation research113(10)1138-47(2013 Oct)
Abonnenc M,Nabeebaccus AA,Mayr U,Barallobre-Barreiro J,Dong X,Cuello F,Sur S,Drozdov I,Langley SR,Lu R,Stathopoulou K,Didangelos A,Yin X,Zimmermann WH,Shah AM,Zampetaki A,Mayr M


book

Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.
Proceedings of the National Academy of Sciences of the United States of America110(6)E507-16(2013 Feb)
Lumayag S,Haldin CE,Corbett NJ,Wahlin KJ,Cowan C,Turturro S,Larsen PE,Kovacs B,Witmer PD,Valle D,Zack DJ,Nicholson DA,Xu S


book

Molecular mechanisms for synchronized transcription of three complement C1q subunit genes in dendritic cells and macrophages.
The Journal of biological chemistry286(40)34941-50(2011 Oct)
Chen G,Tan CS,Teh BK,Lu J