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Csnk2a1 cDNA ORF clone, Mus musculus(house mouse)

Summary

Gene Symbol Csnk2a1
Entrez Gene ID 12995
Full Name casein kinase 2, alpha 1 polypeptide
Synonyms Csnk2a1-rs4
General protein information
Preferred Names

casein kinase 2, alpha 1 polypeptide

Names

casein kinase II subunit alpha
CK II alpha
casein kinase II, alpha 1 polypeptide
casein kinase II, alpha 1 related sequence 4
Gene Type protein-coding
Organism Mus musculus(house mouse)
Genome

2

2|2 G3
Summary Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythms. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. [provided by RefSeq, Feb 2014].

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_006498657.2 XP_006498720.1 casein kinase II subunit alpha isoform X1
XM_006498657.3 XP_006498720.1 casein kinase II subunit alpha isoform X1
NM_007788.3 NP_031814.2 casein kinase II subunit alpha
XM_011239272.1 XP_011237574.1 casein kinase II subunit alpha isoform X1
XM_011239272.2 XP_011237574.1 casein kinase II subunit alpha isoform X1

Pathways from BioSystems


Homologies


Canis lupus familiaris (dog) CSNK2A1 XP_005634959.1
Rattus norvegicus (Norway rat) Csnk2a1 NP_446276.1
Drosophila melanogaster (fruit fly) CkIIalpha NP_730775.1
Saccharomyces cerevisiae (baker's yeast) CKA2 NP_014704.1
Magnaporthe oryzae (rice blast fungus) MGG_03696 XP_003716185.1
Mus musculus (house mouse) Csnk2a1 NP_031814.2
Gallus gallus (chicken) CSNK2A1 NP_001002242.1
Arabidopsis thaliana (thale cress) AT2G23070 NP_179889.1
Xenopus tropicalis (tropical clawed frog) LOC100498392 XP_004920495.1
Homo sapiens (human) CSNK2A1 NP_808227.1
Danio rerio (zebrafish) LOC100535532 XP_003199454.1
Eremothecium gossypii AGOS_ADR204W NP_984300.1
Neurospora crassa NCU03124 XP_964983.2
Bos taurus (cattle) CSNK2A1 NP_777060.2
Anopheles gambiae (African malaria mosquito) AgaP_AGAP005569 XP_315576.4
Caenorhabditis elegans (roundworm) kin-3 NP_492811.1
Pan troglodytes (chimpanzee) CSNK2A1 XP_003953729.1
CSNK2A1 XP_002798227.1
Kluyveromyces lactis KLLA0F16467g XP_455820.1
Schizosaccharomyces pombe (fission yeast) cka1 NP_593642.1

Gene Ontology


Bibliography

Related articles in PubMed

Fc?R/ROS/CK2? Is the Key Inducer of NF-?B Activation in a Murine Model of Asthma.
Kim JM, Kim HK, Im YN, Bae YS, Im SY, Lee HK
International archives of allergy and immunology(2018 Jan)

CK2 Oppositely Modulates l-DOPA-Induced Dyskinesia via Striatal Projection Neurons Expressing D1 or D2 Receptors.
Cort?s M, Malave L, Castello J, Flajolet M, Cenci MA, Friedman E, Rebholz H
The Journal of neuroscience : the official journal of the Society for Neuroscience37(49)11930-11946(2017 Dec)

Casein kinase 2-mediated phosphorylation of Brahma-related gene 1 controls myoblast proliferation and contributes to SWI/SNF complex composition.
Padilla-Benavides T, Nasipak BT, Paskavitz AL, Haokip DT, Schnabl JM, Nickerson JA, Imbalzano AN
The Journal of biological chemistry292(45)18592-18607(2017 11)

Abnormal degradation of the neuronal stress-protective transcription factor HSF1 in Huntington's disease.
Gomez-Pastor R, Burchfiel ET, Neef DW, Jaeger AM, Cabiscol E, McKinstry SU, Doss A, Aballay A, Lo DC, Akimov SS, Ross CA, Eroglu C, Thiele DJ
Nature communications814405(2017 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Casein kinase 2 plays a central role in striatal physiology and in severity of l-DOPA-induced dyskinesia.
Title: CK2 Oppositely Modulates l-DOPA-Induced Dyskinesia via Striatal Projection Neurons Expressing D1 or D2 Receptors.

Data (including data from studies using knockout mice) suggest that Brg1 is phosphorylated by casein kinase 2 (Ck2; Ck2alpha1 and Ck2alpha-prime are catalytic subunits) in proliferating skeletal myoblasts; Brg1 is catalytic subunit of SWI/SNF chromatin-remodeling enzymes; Ck2-mediated phosphorylation of Brg1 appears to regulate myoblast proliferation. (Brg1 = Brahma-related gene 1 protein)
Title: Casein kinase 2-mediated phosphorylation of Brahma-related gene 1 controls myoblast proliferation and contributes to SWI/SNF complex composition.

Casein kinase 1 (alpha, delta and epsilon) localize at the spindle poles, but may not be essential for mammalian oocyte meiotic progression.
Title: Casein kinase 1 (?, ? and ?) localize at the spindle poles, but may not be essential for mammalian oocyte meiotic progression.

These data support a model in which activated Akt enhances rRNA synthesis both by preventing TIF-IA degradation and phosphorylating CK2alpha, which in turn phosphorylates TIF-IA.
Title: Akt activation enhances ribosomal RNA synthesis through casein kinase II and TIF-IA.

An essential role of CK2alpha in the mammalian circadian clock.
Title: An in vitro ES cell-based clock recapitulation assay model identifies CK2? as an endogenous clock regulator.

The following Csnk2a1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Csnk2a1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OMu21259 NM_007788.3
Latest version!		 Mus musculus casein kinase 2, alpha 1 polypeptide (Csnk2a1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $159.50-$223.30
$319.00
OMu21259 XM_011239272.2
Latest version!		 Mus musculus casein kinase 2, alpha 1 polypeptide (Csnk2a1), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $159.50-$223.30
$319.00
OMu21259 XM_006498657.3
Latest version!		 Mus musculus casein kinase 2, alpha 1 polypeptide (Csnk2a1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $159.50-$223.30
$319.00
View Old Accession Versions >>
OMu21259 XM_006498657.2 Mus musculus casein kinase 2, alpha 1 polypeptide (Csnk2a1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $159.50-$223.30
$319.00
OMu21259 XM_011239272.1 Mus musculus casein kinase 2, alpha 1 polypeptide (Csnk2a1), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $159.50-$223.30
$319.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OMu21259
Clone ID Related Accession (Same CDS sequence) XM_006498657.2 , XM_006498657.3 , NM_007788.3 , XM_011239272.1 , XM_011239272.2
Accession Version NM_007788.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1176bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-02-20
Organism Mus musculus(house mouse)
Product casein kinase II subunit alpha
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY015187.1, AK146032.1, AK042898.1, CA322616.1 and BF018216.1. On Jan 10, 2008 this sequence version replaced NM_007788.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC060742.1, AK146032.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
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541
601
661
721
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841
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961
1021
1081
1141
ATGTCGGGAC CCGTGCCAAG CAGGGCCAGA GTTTACACAG ATGTTAACAC ACACAGACCC 
CGAGAGTACT GGGATTATGA ATCACATGTG GTGGAATGGG GGAATCAAGA TGACTATCAG 
CTTGTTCGAA AATTAGGTAG GGGCAAATAC AGTGAAGTGT TTGAAGCCAT CAACATCACA 
AATAATGAAA AAGTTGTTGT TAAAATTCTC AAGCCAGTAA AAAAGAAGAA AATTAAGCGT 
GAAATAAAGA TTTTGGAGAA TTTGAGAGGT GGGCCCAACA TCATCACACT TGCAGACATT 
GTAAAAGACC CTGTGTCACG AACCCCTGCC TTGGTTTTTG AACATGTAAA CAACACAGAC 
TTCAAGCAAT TGTACCAGAC GTTAACAGAC TATGACATTC GATTTTACAT GTATGAAATT 
CTGAAAGCCC TGGATTATTG TCACAGCATG GGGATTATGC ACAGAGATGT GAAACCCCAT 
AATGTCATGA TTGATCATGA GCACAGAAAG CTTCGGCTAA TAGACTGGGG TTTAGCTGAG 
TTTTACCATC CAGGCCAAGA GTATAATGTC CGAGTTGCTT CTCGATATTT CAAAGGTCCA 
GAGCTACTTG TAGATTATCA GATGTACGAT TATAGTTTGG ATATGTGGAG CTTGGGTTGT 
ATGCTGGCCA GTATGATCTT CCGGAAGGAG CCATTTTTCC ATGGACATGA CAATTATGAT 
CAGTTGGTGA GGATAGCCAA GGTTCTGGGA ACAGAAGATT TATATGACTA TATTGACAAG 
TACAACATTG AATTAGATCC ACGTTTCAAC GATATCTTGG GCAGACACTC CCGTAAGCGA 
TGGGAACGCT TTGTCCACAG TGAAAACCAG CATCTTGTCA GCCCTGAGGC CTTGGATTTT 
CTGGACAAGC TGCTTCGATA TGACCACCAG TCACGGCTCA CTGCAAGAGA GGCCATGGAG 
CACCCTTACT TCTACACTGT TGTGAAGGAC CAGGCTCGAA TGAGTTCCAC TAGCATGGCA 
GGGGGCAGCA CACCTGTCAG CAGCGCCAAT ATGATGTCAG GGATTTCTTC AGTGCCAACT 
CCTTCACCCC TTGGACCTCT GGCAGGCTCA CCAGTGATTG CCGCTGCCAA CTCACTTGGG 
ATACCTGTTC CAGCTGCTGC TGGCGCTCAG CAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_031814.2
CDS262..1437
Translation

Target ORF information:

RefSeq Version NM_007788.3
Organism Mus musculus(house mouse)
Definition Mus musculus casein kinase 2, alpha 1 polypeptide (Csnk2a1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_007788.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGTCGGGAC CCGTGCCAAG CAGGGCCAGA GTTTACACAG ATGTTAACAC ACACAGACCC 
CGAGAGTACT GGGATTATGA ATCACATGTG GTGGAATGGG GGAATCAAGA TGACTATCAG 
CTTGTTCGAA AATTAGGTAG GGGCAAATAC AGTGAAGTGT TTGAAGCCAT CAACATCACA 
AATAATGAAA AAGTTGTTGT TAAAATTCTC AAGCCAGTAA AAAAGAAGAA AATTAAGCGT 
GAAATAAAGA TTTTGGAGAA TTTGAGAGGT GGGCCCAACA TCATCACACT TGCAGACATT 
GTAAAAGACC CTGTGTCACG AACCCCTGCC TTGGTTTTTG AACATGTAAA CAACACAGAC 
TTCAAGCAAT TGTACCAGAC GTTAACAGAC TATGACATTC GATTTTACAT GTATGAAATT 
CTGAAAGCCC TGGATTATTG TCACAGCATG GGGATTATGC ACAGAGATGT GAAACCCCAT 
AATGTCATGA TTGATCATGA GCACAGAAAG CTTCGGCTAA TAGACTGGGG TTTAGCTGAG 
TTTTACCATC CAGGCCAAGA GTATAATGTC CGAGTTGCTT CTCGATATTT CAAAGGTCCA 
GAGCTACTTG TAGATTATCA GATGTACGAT TATAGTTTGG ATATGTGGAG CTTGGGTTGT 
ATGCTGGCCA GTATGATCTT CCGGAAGGAG CCATTTTTCC ATGGACATGA CAATTATGAT 
CAGTTGGTGA GGATAGCCAA GGTTCTGGGA ACAGAAGATT TATATGACTA TATTGACAAG 
TACAACATTG AATTAGATCC ACGTTTCAAC GATATCTTGG GCAGACACTC CCGTAAGCGA 
TGGGAACGCT TTGTCCACAG TGAAAACCAG CATCTTGTCA GCCCTGAGGC CTTGGATTTT 
CTGGACAAGC TGCTTCGATA TGACCACCAG TCACGGCTCA CTGCAAGAGA GGCCATGGAG 
CACCCTTACT TCTACACTGT TGTGAAGGAC CAGGCTCGAA TGAGTTCCAC TAGCATGGCA 
GGGGGCAGCA CACCTGTCAG CAGCGCCAAT ATGATGTCAG GGATTTCTTC AGTGCCAACT 
CCTTCACCCC TTGGACCTCT GGCAGGCTCA CCAGTGATTG CCGCTGCCAA CTCACTTGGG 
ATACCTGTTC CAGCTGCTGC TGGCGCTCAG CAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu21259
Clone ID Related Accession (Same CDS sequence) XM_006498657.2 , XM_006498657.3 , NM_007788.3 , XM_011239272.1 , XM_011239272.2
Accession Version XM_006498657.2 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1176bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2015-02-08
Organism Mus musculus(House mouse)
Product casein kinase II subunit alpha isoform X1
Comment 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGTCGGGAC CCGTGCCAAG CAGGGCCAGA GTTTACACAG ATGTTAACAC ACACAGACCC 
CGAGAGTACT GGGATTATGA ATCACATGTG GTGGAATGGG GGAATCAAGA TGACTATCAG 
CTTGTTCGAA AATTAGGTAG GGGCAAATAC AGTGAAGTGT TTGAAGCCAT CAACATCACA 
AATAATGAAA AAGTTGTTGT TAAAATTCTC AAGCCAGTAA AAAAGAAGAA AATTAAGCGT 
GAAATAAAGA TTTTGGAGAA TTTGAGAGGT GGGCCCAACA TCATCACACT TGCAGACATT 
GTAAAAGACC CTGTGTCACG AACCCCTGCC TTGGTTTTTG AACATGTAAA CAACACAGAC 
TTCAAGCAAT TGTACCAGAC GTTAACAGAC TATGACATTC GATTTTACAT GTATGAAATT 
CTGAAAGCCC TGGATTATTG TCACAGCATG GGGATTATGC ACAGAGATGT GAAACCCCAT 
AATGTCATGA TTGATCATGA GCACAGAAAG CTTCGGCTAA TAGACTGGGG TTTAGCTGAG 
TTTTACCATC CAGGCCAAGA GTATAATGTC CGAGTTGCTT CTCGATATTT CAAAGGTCCA 
GAGCTACTTG TAGATTATCA GATGTACGAT TATAGTTTGG ATATGTGGAG CTTGGGTTGT 
ATGCTGGCCA GTATGATCTT CCGGAAGGAG CCATTTTTCC ATGGACATGA CAATTATGAT 
CAGTTGGTGA GGATAGCCAA GGTTCTGGGA ACAGAAGATT TATATGACTA TATTGACAAG 
TACAACATTG AATTAGATCC ACGTTTCAAC GATATCTTGG GCAGACACTC CCGTAAGCGA 
TGGGAACGCT TTGTCCACAG TGAAAACCAG CATCTTGTCA GCCCTGAGGC CTTGGATTTT 
CTGGACAAGC TGCTTCGATA TGACCACCAG TCACGGCTCA CTGCAAGAGA GGCCATGGAG 
CACCCTTACT TCTACACTGT TGTGAAGGAC CAGGCTCGAA TGAGTTCCAC TAGCATGGCA 
GGGGGCAGCA CACCTGTCAG CAGCGCCAAT ATGATGTCAG GGATTTCTTC AGTGCCAACT 
CCTTCACCCC TTGGACCTCT GGCAGGCTCA CCAGTGATTG CCGCTGCCAA CTCACTTGGG 
ATACCTGTTC CAGCTGCTGC TGGCGCTCAG CAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006498720.1
Translation

Target ORF information:

RefSeq Version XM_006498657.2
Organism Mus musculus(House mouse)
Definition Mus musculus casein kinase 2, alpha 1 polypeptide (Csnk2a1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006498657.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGTCGGGAC CCGTGCCAAG CAGGGCCAGA GTTTACACAG ATGTTAACAC ACACAGACCC 
CGAGAGTACT GGGATTATGA ATCACATGTG GTGGAATGGG GGAATCAAGA TGACTATCAG 
CTTGTTCGAA AATTAGGTAG GGGCAAATAC AGTGAAGTGT TTGAAGCCAT CAACATCACA 
AATAATGAAA AAGTTGTTGT TAAAATTCTC AAGCCAGTAA AAAAGAAGAA AATTAAGCGT 
GAAATAAAGA TTTTGGAGAA TTTGAGAGGT GGGCCCAACA TCATCACACT TGCAGACATT 
GTAAAAGACC CTGTGTCACG AACCCCTGCC TTGGTTTTTG AACATGTAAA CAACACAGAC 
TTCAAGCAAT TGTACCAGAC GTTAACAGAC TATGACATTC GATTTTACAT GTATGAAATT 
CTGAAAGCCC TGGATTATTG TCACAGCATG GGGATTATGC ACAGAGATGT GAAACCCCAT 
AATGTCATGA TTGATCATGA GCACAGAAAG CTTCGGCTAA TAGACTGGGG TTTAGCTGAG 
TTTTACCATC CAGGCCAAGA GTATAATGTC CGAGTTGCTT CTCGATATTT CAAAGGTCCA 
GAGCTACTTG TAGATTATCA GATGTACGAT TATAGTTTGG ATATGTGGAG CTTGGGTTGT 
ATGCTGGCCA GTATGATCTT CCGGAAGGAG CCATTTTTCC ATGGACATGA CAATTATGAT 
CAGTTGGTGA GGATAGCCAA GGTTCTGGGA ACAGAAGATT TATATGACTA TATTGACAAG 
TACAACATTG AATTAGATCC ACGTTTCAAC GATATCTTGG GCAGACACTC CCGTAAGCGA 
TGGGAACGCT TTGTCCACAG TGAAAACCAG CATCTTGTCA GCCCTGAGGC CTTGGATTTT 
CTGGACAAGC TGCTTCGATA TGACCACCAG TCACGGCTCA CTGCAAGAGA GGCCATGGAG 
CACCCTTACT TCTACACTGT TGTGAAGGAC CAGGCTCGAA TGAGTTCCAC TAGCATGGCA 
GGGGGCAGCA CACCTGTCAG CAGCGCCAAT ATGATGTCAG GGATTTCTTC AGTGCCAACT 
CCTTCACCCC TTGGACCTCT GGCAGGCTCA CCAGTGATTG CCGCTGCCAA CTCACTTGGG 
ATACCTGTTC CAGCTGCTGC TGGCGCTCAG CAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu21259
Clone ID Related Accession (Same CDS sequence) XM_006498657.2 , XM_006498657.3 , NM_007788.3 , XM_011239272.1 , XM_011239272.2
Accession Version XM_006498657.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1176bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-21
Organism Mus musculus(house mouse)
Product casein kinase II subunit alpha isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006498657.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
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601
661
721
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841
901
961
1021
1081
1141
ATGTCGGGAC CCGTGCCAAG CAGGGCCAGA GTTTACACAG ATGTTAACAC ACACAGACCC 
CGAGAGTACT GGGATTATGA ATCACATGTG GTGGAATGGG GGAATCAAGA TGACTATCAG 
CTTGTTCGAA AATTAGGTAG GGGCAAATAC AGTGAAGTGT TTGAAGCCAT CAACATCACA 
AATAATGAAA AAGTTGTTGT TAAAATTCTC AAGCCAGTAA AAAAGAAGAA AATTAAGCGT 
GAAATAAAGA TTTTGGAGAA TTTGAGAGGT GGGCCCAACA TCATCACACT TGCAGACATT 
GTAAAAGACC CTGTGTCACG AACCCCTGCC TTGGTTTTTG AACATGTAAA CAACACAGAC 
TTCAAGCAAT TGTACCAGAC GTTAACAGAC TATGACATTC GATTTTACAT GTATGAAATT 
CTGAAAGCCC TGGATTATTG TCACAGCATG GGGATTATGC ACAGAGATGT GAAACCCCAT 
AATGTCATGA TTGATCATGA GCACAGAAAG CTTCGGCTAA TAGACTGGGG TTTAGCTGAG 
TTTTACCATC CAGGCCAAGA GTATAATGTC CGAGTTGCTT CTCGATATTT CAAAGGTCCA 
GAGCTACTTG TAGATTATCA GATGTACGAT TATAGTTTGG ATATGTGGAG CTTGGGTTGT 
ATGCTGGCCA GTATGATCTT CCGGAAGGAG CCATTTTTCC ATGGACATGA CAATTATGAT 
CAGTTGGTGA GGATAGCCAA GGTTCTGGGA ACAGAAGATT TATATGACTA TATTGACAAG 
TACAACATTG AATTAGATCC ACGTTTCAAC GATATCTTGG GCAGACACTC CCGTAAGCGA 
TGGGAACGCT TTGTCCACAG TGAAAACCAG CATCTTGTCA GCCCTGAGGC CTTGGATTTT 
CTGGACAAGC TGCTTCGATA TGACCACCAG TCACGGCTCA CTGCAAGAGA GGCCATGGAG 
CACCCTTACT TCTACACTGT TGTGAAGGAC CAGGCTCGAA TGAGTTCCAC TAGCATGGCA 
GGGGGCAGCA CACCTGTCAG CAGCGCCAAT ATGATGTCAG GGATTTCTTC AGTGCCAACT 
CCTTCACCCC TTGGACCTCT GGCAGGCTCA CCAGTGATTG CCGCTGCCAA CTCACTTGGG 
ATACCTGTTC CAGCTGCTGC TGGCGCTCAG CAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006498720.1
CDS305..1480
Translation

Target ORF information:

RefSeq Version XM_006498657.3
Organism Mus musculus(house mouse)
Definition Mus musculus casein kinase 2, alpha 1 polypeptide (Csnk2a1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006498657.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGTCGGGAC CCGTGCCAAG CAGGGCCAGA GTTTACACAG ATGTTAACAC ACACAGACCC 
CGAGAGTACT GGGATTATGA ATCACATGTG GTGGAATGGG GGAATCAAGA TGACTATCAG 
CTTGTTCGAA AATTAGGTAG GGGCAAATAC AGTGAAGTGT TTGAAGCCAT CAACATCACA 
AATAATGAAA AAGTTGTTGT TAAAATTCTC AAGCCAGTAA AAAAGAAGAA AATTAAGCGT 
GAAATAAAGA TTTTGGAGAA TTTGAGAGGT GGGCCCAACA TCATCACACT TGCAGACATT 
GTAAAAGACC CTGTGTCACG AACCCCTGCC TTGGTTTTTG AACATGTAAA CAACACAGAC 
TTCAAGCAAT TGTACCAGAC GTTAACAGAC TATGACATTC GATTTTACAT GTATGAAATT 
CTGAAAGCCC TGGATTATTG TCACAGCATG GGGATTATGC ACAGAGATGT GAAACCCCAT 
AATGTCATGA TTGATCATGA GCACAGAAAG CTTCGGCTAA TAGACTGGGG TTTAGCTGAG 
TTTTACCATC CAGGCCAAGA GTATAATGTC CGAGTTGCTT CTCGATATTT CAAAGGTCCA 
GAGCTACTTG TAGATTATCA GATGTACGAT TATAGTTTGG ATATGTGGAG CTTGGGTTGT 
ATGCTGGCCA GTATGATCTT CCGGAAGGAG CCATTTTTCC ATGGACATGA CAATTATGAT 
CAGTTGGTGA GGATAGCCAA GGTTCTGGGA ACAGAAGATT TATATGACTA TATTGACAAG 
TACAACATTG AATTAGATCC ACGTTTCAAC GATATCTTGG GCAGACACTC CCGTAAGCGA 
TGGGAACGCT TTGTCCACAG TGAAAACCAG CATCTTGTCA GCCCTGAGGC CTTGGATTTT 
CTGGACAAGC TGCTTCGATA TGACCACCAG TCACGGCTCA CTGCAAGAGA GGCCATGGAG 
CACCCTTACT TCTACACTGT TGTGAAGGAC CAGGCTCGAA TGAGTTCCAC TAGCATGGCA 
GGGGGCAGCA CACCTGTCAG CAGCGCCAAT ATGATGTCAG GGATTTCTTC AGTGCCAACT 
CCTTCACCCC TTGGACCTCT GGCAGGCTCA CCAGTGATTG CCGCTGCCAA CTCACTTGGG 
ATACCTGTTC CAGCTGCTGC TGGCGCTCAG CAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu21259
Clone ID Related Accession (Same CDS sequence) XM_006498657.2 , XM_006498657.3 , NM_007788.3 , XM_011239272.1 , XM_011239272.2
Accession Version XM_011239272.1 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1176bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2015-02-08
Organism Mus musculus(House mouse)
Product casein kinase II subunit alpha isoform X1
Comment 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGTCGGGAC CCGTGCCAAG CAGGGCCAGA GTTTACACAG ATGTTAACAC ACACAGACCC 
CGAGAGTACT GGGATTATGA ATCACATGTG GTGGAATGGG GGAATCAAGA TGACTATCAG 
CTTGTTCGAA AATTAGGTAG GGGCAAATAC AGTGAAGTGT TTGAAGCCAT CAACATCACA 
AATAATGAAA AAGTTGTTGT TAAAATTCTC AAGCCAGTAA AAAAGAAGAA AATTAAGCGT 
GAAATAAAGA TTTTGGAGAA TTTGAGAGGT GGGCCCAACA TCATCACACT TGCAGACATT 
GTAAAAGACC CTGTGTCACG AACCCCTGCC TTGGTTTTTG AACATGTAAA CAACACAGAC 
TTCAAGCAAT TGTACCAGAC GTTAACAGAC TATGACATTC GATTTTACAT GTATGAAATT 
CTGAAAGCCC TGGATTATTG TCACAGCATG GGGATTATGC ACAGAGATGT GAAACCCCAT 
AATGTCATGA TTGATCATGA GCACAGAAAG CTTCGGCTAA TAGACTGGGG TTTAGCTGAG 
TTTTACCATC CAGGCCAAGA GTATAATGTC CGAGTTGCTT CTCGATATTT CAAAGGTCCA 
GAGCTACTTG TAGATTATCA GATGTACGAT TATAGTTTGG ATATGTGGAG CTTGGGTTGT 
ATGCTGGCCA GTATGATCTT CCGGAAGGAG CCATTTTTCC ATGGACATGA CAATTATGAT 
CAGTTGGTGA GGATAGCCAA GGTTCTGGGA ACAGAAGATT TATATGACTA TATTGACAAG 
TACAACATTG AATTAGATCC ACGTTTCAAC GATATCTTGG GCAGACACTC CCGTAAGCGA 
TGGGAACGCT TTGTCCACAG TGAAAACCAG CATCTTGTCA GCCCTGAGGC CTTGGATTTT 
CTGGACAAGC TGCTTCGATA TGACCACCAG TCACGGCTCA CTGCAAGAGA GGCCATGGAG 
CACCCTTACT TCTACACTGT TGTGAAGGAC CAGGCTCGAA TGAGTTCCAC TAGCATGGCA 
GGGGGCAGCA CACCTGTCAG CAGCGCCAAT ATGATGTCAG GGATTTCTTC AGTGCCAACT 
CCTTCACCCC TTGGACCTCT GGCAGGCTCA CCAGTGATTG CCGCTGCCAA CTCACTTGGG 
ATACCTGTTC CAGCTGCTGC TGGCGCTCAG CAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011237574.1
Translation

Target ORF information:

RefSeq Version XM_011239272.1
Organism Mus musculus(House mouse)
Definition Mus musculus casein kinase 2, alpha 1 polypeptide (Csnk2a1), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_011239272.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGTCGGGAC CCGTGCCAAG CAGGGCCAGA GTTTACACAG ATGTTAACAC ACACAGACCC 
CGAGAGTACT GGGATTATGA ATCACATGTG GTGGAATGGG GGAATCAAGA TGACTATCAG 
CTTGTTCGAA AATTAGGTAG GGGCAAATAC AGTGAAGTGT TTGAAGCCAT CAACATCACA 
AATAATGAAA AAGTTGTTGT TAAAATTCTC AAGCCAGTAA AAAAGAAGAA AATTAAGCGT 
GAAATAAAGA TTTTGGAGAA TTTGAGAGGT GGGCCCAACA TCATCACACT TGCAGACATT 
GTAAAAGACC CTGTGTCACG AACCCCTGCC TTGGTTTTTG AACATGTAAA CAACACAGAC 
TTCAAGCAAT TGTACCAGAC GTTAACAGAC TATGACATTC GATTTTACAT GTATGAAATT 
CTGAAAGCCC TGGATTATTG TCACAGCATG GGGATTATGC ACAGAGATGT GAAACCCCAT 
AATGTCATGA TTGATCATGA GCACAGAAAG CTTCGGCTAA TAGACTGGGG TTTAGCTGAG 
TTTTACCATC CAGGCCAAGA GTATAATGTC CGAGTTGCTT CTCGATATTT CAAAGGTCCA 
GAGCTACTTG TAGATTATCA GATGTACGAT TATAGTTTGG ATATGTGGAG CTTGGGTTGT 
ATGCTGGCCA GTATGATCTT CCGGAAGGAG CCATTTTTCC ATGGACATGA CAATTATGAT 
CAGTTGGTGA GGATAGCCAA GGTTCTGGGA ACAGAAGATT TATATGACTA TATTGACAAG 
TACAACATTG AATTAGATCC ACGTTTCAAC GATATCTTGG GCAGACACTC CCGTAAGCGA 
TGGGAACGCT TTGTCCACAG TGAAAACCAG CATCTTGTCA GCCCTGAGGC CTTGGATTTT 
CTGGACAAGC TGCTTCGATA TGACCACCAG TCACGGCTCA CTGCAAGAGA GGCCATGGAG 
CACCCTTACT TCTACACTGT TGTGAAGGAC CAGGCTCGAA TGAGTTCCAC TAGCATGGCA 
GGGGGCAGCA CACCTGTCAG CAGCGCCAAT ATGATGTCAG GGATTTCTTC AGTGCCAACT 
CCTTCACCCC TTGGACCTCT GGCAGGCTCA CCAGTGATTG CCGCTGCCAA CTCACTTGGG 
ATACCTGTTC CAGCTGCTGC TGGCGCTCAG CAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu21259
Clone ID Related Accession (Same CDS sequence) XM_006498657.2 , XM_006498657.3 , NM_007788.3 , XM_011239272.1 , XM_011239272.2
Accession Version XM_011239272.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1176bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-21
Organism Mus musculus(house mouse)
Product casein kinase II subunit alpha isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011239272.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGTCGGGAC CCGTGCCAAG CAGGGCCAGA GTTTACACAG ATGTTAACAC ACACAGACCC 
CGAGAGTACT GGGATTATGA ATCACATGTG GTGGAATGGG GGAATCAAGA TGACTATCAG 
CTTGTTCGAA AATTAGGTAG GGGCAAATAC AGTGAAGTGT TTGAAGCCAT CAACATCACA 
AATAATGAAA AAGTTGTTGT TAAAATTCTC AAGCCAGTAA AAAAGAAGAA AATTAAGCGT 
GAAATAAAGA TTTTGGAGAA TTTGAGAGGT GGGCCCAACA TCATCACACT TGCAGACATT 
GTAAAAGACC CTGTGTCACG AACCCCTGCC TTGGTTTTTG AACATGTAAA CAACACAGAC 
TTCAAGCAAT TGTACCAGAC GTTAACAGAC TATGACATTC GATTTTACAT GTATGAAATT 
CTGAAAGCCC TGGATTATTG TCACAGCATG GGGATTATGC ACAGAGATGT GAAACCCCAT 
AATGTCATGA TTGATCATGA GCACAGAAAG CTTCGGCTAA TAGACTGGGG TTTAGCTGAG 
TTTTACCATC CAGGCCAAGA GTATAATGTC CGAGTTGCTT CTCGATATTT CAAAGGTCCA 
GAGCTACTTG TAGATTATCA GATGTACGAT TATAGTTTGG ATATGTGGAG CTTGGGTTGT 
ATGCTGGCCA GTATGATCTT CCGGAAGGAG CCATTTTTCC ATGGACATGA CAATTATGAT 
CAGTTGGTGA GGATAGCCAA GGTTCTGGGA ACAGAAGATT TATATGACTA TATTGACAAG 
TACAACATTG AATTAGATCC ACGTTTCAAC GATATCTTGG GCAGACACTC CCGTAAGCGA 
TGGGAACGCT TTGTCCACAG TGAAAACCAG CATCTTGTCA GCCCTGAGGC CTTGGATTTT 
CTGGACAAGC TGCTTCGATA TGACCACCAG TCACGGCTCA CTGCAAGAGA GGCCATGGAG 
CACCCTTACT TCTACACTGT TGTGAAGGAC CAGGCTCGAA TGAGTTCCAC TAGCATGGCA 
GGGGGCAGCA CACCTGTCAG CAGCGCCAAT ATGATGTCAG GGATTTCTTC AGTGCCAACT 
CCTTCACCCC TTGGACCTCT GGCAGGCTCA CCAGTGATTG CCGCTGCCAA CTCACTTGGG 
ATACCTGTTC CAGCTGCTGC TGGCGCTCAG CAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011237574.1
CDS229..1404
Translation

Target ORF information:

RefSeq Version XM_011239272.2
Organism Mus musculus(house mouse)
Definition Mus musculus casein kinase 2, alpha 1 polypeptide (Csnk2a1), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_011239272.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGTCGGGAC CCGTGCCAAG CAGGGCCAGA GTTTACACAG ATGTTAACAC ACACAGACCC 
CGAGAGTACT GGGATTATGA ATCACATGTG GTGGAATGGG GGAATCAAGA TGACTATCAG 
CTTGTTCGAA AATTAGGTAG GGGCAAATAC AGTGAAGTGT TTGAAGCCAT CAACATCACA 
AATAATGAAA AAGTTGTTGT TAAAATTCTC AAGCCAGTAA AAAAGAAGAA AATTAAGCGT 
GAAATAAAGA TTTTGGAGAA TTTGAGAGGT GGGCCCAACA TCATCACACT TGCAGACATT 
GTAAAAGACC CTGTGTCACG AACCCCTGCC TTGGTTTTTG AACATGTAAA CAACACAGAC 
TTCAAGCAAT TGTACCAGAC GTTAACAGAC TATGACATTC GATTTTACAT GTATGAAATT 
CTGAAAGCCC TGGATTATTG TCACAGCATG GGGATTATGC ACAGAGATGT GAAACCCCAT 
AATGTCATGA TTGATCATGA GCACAGAAAG CTTCGGCTAA TAGACTGGGG TTTAGCTGAG 
TTTTACCATC CAGGCCAAGA GTATAATGTC CGAGTTGCTT CTCGATATTT CAAAGGTCCA 
GAGCTACTTG TAGATTATCA GATGTACGAT TATAGTTTGG ATATGTGGAG CTTGGGTTGT 
ATGCTGGCCA GTATGATCTT CCGGAAGGAG CCATTTTTCC ATGGACATGA CAATTATGAT 
CAGTTGGTGA GGATAGCCAA GGTTCTGGGA ACAGAAGATT TATATGACTA TATTGACAAG 
TACAACATTG AATTAGATCC ACGTTTCAAC GATATCTTGG GCAGACACTC CCGTAAGCGA 
TGGGAACGCT TTGTCCACAG TGAAAACCAG CATCTTGTCA GCCCTGAGGC CTTGGATTTT 
CTGGACAAGC TGCTTCGATA TGACCACCAG TCACGGCTCA CTGCAAGAGA GGCCATGGAG 
CACCCTTACT TCTACACTGT TGTGAAGGAC CAGGCTCGAA TGAGTTCCAC TAGCATGGCA 
GGGGGCAGCA CACCTGTCAG CAGCGCCAAT ATGATGTCAG GGATTTCTTC AGTGCCAACT 
CCTTCACCCC TTGGACCTCT GGCAGGCTCA CCAGTGATTG CCGCTGCCAA CTCACTTGGG 
ATACCTGTTC CAGCTGCTGC TGGCGCTCAG CAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Fc?R/ROS/CK2? Is the Key Inducer of NF-?B Activation in a Murine Model of Asthma.
International archives of allergy and immunology(2018 Jan)
Kim JM,Kim HK,Im YN,Bae YS,Im SY,Lee HK


book

CK2 Oppositely Modulates l-DOPA-Induced Dyskinesia via Striatal Projection Neurons Expressing D1 or D2 Receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience37(49)11930-11946(2017 Dec)
Cort?s M,Malave L,Castello J,Flajolet M,Cenci MA,Friedman E,Rebholz H


book

Casein kinase 2-mediated phosphorylation of Brahma-related gene 1 controls myoblast proliferation and contributes to SWI/SNF complex composition.
The Journal of biological chemistry292(45)18592-18607(2017 11)
Padilla-Benavides T,Nasipak BT,Paskavitz AL,Haokip DT,Schnabl JM,Nickerson JA,Imbalzano AN


book

Abnormal degradation of the neuronal stress-protective transcription factor HSF1 in Huntington's disease.
Nature communications814405(2017 Feb)
Gomez-Pastor R,Burchfiel ET,Neef DW,Jaeger AM,Cabiscol E,McKinstry SU,Doss A,Aballay A,Lo DC,Akimov SS,Ross CA,Eroglu C,Thiele DJ