Gene Symbol | RBM24 |
Entrez Gene ID | 221662 |
Full Name | RNA binding motif protein 24 |
Synonyms | RNPC6,dJ259A10.1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » RBM24 cDNA ORF clone
gRNAs
Gene Symbol | RBM24 |
Entrez Gene ID | 221662 |
Full Name | RNA binding motif protein 24 |
Synonyms | RNPC6,dJ259A10.1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_001143942.2 | NP_001137414.1 | RNA-binding protein 24 isoform 1 |
XM_011514387.2 | XP_011512689.1 | RNA-binding protein 24 isoform X1 |
XM_011514388.2 | XP_011512690.1 | RNA-binding protein 24 isoform X2 |
XM_011514389.2 | XP_011512691.1 | RNA-binding protein 24 isoform X3 |
NM_001143941.1 | NP_001137413.1 | RNA-binding protein 24 isoform 3 |
XM_005248932.3 | XP_005248989.1 | RNA-binding protein 24 isoform X4 |
NM_153020.2 | NP_694565.1 | RNA-binding protein 24 isoform 2 |
NM_001143942.1 | NP_001137414.1 | RNA-binding protein 24 isoform 1 |
Canis lupus familiaris (dog) | RBM24 | XP_005640117.1 |
Mus musculus (house mouse) | Rbm24 | NP_001074894.1 |
Homo sapiens (human) | RBM24 | NP_001137414.1 |
Bos taurus (cattle) | RBM24 | NP_001098455.1 |
Xenopus tropicalis (tropical clawed frog) | rbm24 | NP_989016.1 |
Rattus norvegicus (Norway rat) | Rbm24 | NP_001178029.1 |
Danio rerio (zebrafish) | rbm24a | NP_998030.1 |
Pan troglodytes (chimpanzee) | RBM24 | XP_001175216.2 |
Rbm24, a target of p53, is necessary for proper expression of p53 and heart development.
Zhang M, Zhang Y, Xu E, Mohibi S, de Anda DM, Jiang Y, Zhang J, Chen X
Cell death and differentiation(2018 Jan)
Global profiling of Rbm24 bound RNAs uncovers a multi-tasking RNA binding protein.
Lin Y, Tan KT, Liu J, Kong X, Huang Z, Xu XQ
The international journal of biochemistry & cell biology9410-21(2018 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Our results show that tissue-specific expression of RBM24 can explain the neuron-specific aberrant splicing of IKBKAP exon 20 in familial dysautonomia, and that ectopic expression of RBM24 in neuronal tissue could be a novel therapeutic target of the disease.
Title: RBM24 promotes U1 snRNP recognition of the mutated 5' splice site in the
RBM24 acts at least in part through upregulating the expression of miR-25, which in turn targets MALAT1 for degradation.
Title: RBM24 suppresses cancer progression by upregulating miR-25 to target MALAT1 in nasopharyngeal carcinoma.
embryonic stem cell switching into the differentiation state can be initiated by a tissue-specific splicing regulator, Rbm24.
Title: Rbm24 Regulates Alternative Splicing Switch in Embryonic Stem Cell Cardiac Lineage Differentiation.
Authors have identified a new function of microRNA-222 leading to alteration of myogenic differentiation at the level of alternative splicing, and provided evidence that this effect is mediated by Rbm24 protein.
Title: MicroRNA-222 regulates muscle alternative splicing through Rbm24 during differentiation of skeletal muscle cells.
Study suggests that p63 is regulated by RBM24 via mRNA stability, which gives an insight into understanding how posttranscriptional regulatory mechanisms contribute to p63 expression.
Title: RNA-binding protein RBM24 regulates p63 expression via mRNA stability.
The following RBM24 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RBM24 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu15829![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_001143942.2 , NM_001143942.1 | |
Accession Version | NM_001143942.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 711bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-11-25 | |
Organism | Homo sapiens(human) | |
Product | RNA-binding protein 24 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL136305.14, AK315856.1 and BC040928.1. On Nov 22, 2018 this sequence version replaced NM_001143942.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.144858.1, SRR1660807.195844.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000379052.10/ ENSP00000368341.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGCACACGA CCCAGAAGGA CACGACGTAC ACCAAGATCT TCGTCGGGGG GCTGCCCTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001137414.1 |
CDS | 222..932 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCACACGA CCCAGAAGGA CACGACGTAC ACCAAGATCT TCGTCGGGGG GCTGCCCTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu15829![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_001143942.2 , NM_001143942.1 | |
Accession Version | NM_001143942.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 711bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-12-10 | |
Organism | Homo sapiens(human) | |
Product | RNA-binding protein 24 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK315856.1 and BC040928.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). ##Evidence-Data-START## Transcript exon combination :: AK315856.1, SRR1660805.144858.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCACACGA CCCAGAAGGA CACGACGTAC ACCAAGATCT TCGTCGGGGG GCTGCCCTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001137414.1 |
CDS | 5..715 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCACACGA CCCAGAAGGA CACGACGTAC ACCAAGATCT TCGTCGGGGG GCTGCCCTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu15832![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_001143941.1 | |
Accession Version | NM_001143941.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 537bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-11-25 | |
Organism | Homo sapiens(human) | |
Product | RNA-binding protein 24 isoform 3 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP309176.1, AL136305.14, AK055391.1 and BC040928.1. Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (3) is shorter at the N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BP309176.1, SRR1660809.60481.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2145245 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCTGACC GGGCTGCTGC CGAAAGGGCC TGCAAGGATC CCAATCCCAT CATTGATGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001137413.1 |
CDS | 163..699 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCTGACC GGGCTGCTGC CGAAAGGGCC TGCAAGGATC CCAATCCCAT CATTGATGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu15916![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_153020.2 | |
Accession Version | NM_153020.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 576bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-27 | |
Organism | Homo sapiens(human) | |
Product | RNA-binding protein 24 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK055391.1, AL136305.14 and BC040928.1. On Jan 22, 2009 this sequence version replaced NM_153020.1. Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK055391.1, SRR1660807.20067.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTATGTAT GTCTGTGTGT GTCTGTTGCT AAGGTCACCA TGGCTGACCG GGCTGCTGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_694565.1 |
CDS | 72..647 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTATGTAT GTCTGTGTGT GTCTGTTGCT AAGGTCACCA TGGCTGACCG GGCTGCTGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu40206 | |
Clone ID Related Accession (Same CDS sequence) | XM_005248932.3 | |
Accession Version | XM_005248932.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 366bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | RNA-binding protein 24 isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005248932.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCACACGA CCCAGAAGGA CACGACGTAC ACCAAGATCT TCGTCGGGGG GCTGCCCTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005248989.1 |
CDS | 75..440 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGCACACGA CCCAGAAGGA CACGACGTAC ACCAAGATCT TCGTCGGGGG GCTGCCCTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu78054 | |
Clone ID Related Accession (Same CDS sequence) | XM_011514387.2 | |
Accession Version | XM_011514387.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 522bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | RNA-binding protein 24 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011514387.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTGACC GGGCTGCTGC CGAAAGGGCC TGCAAGGATC CCAATCCCAT CATTGATGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011512689.1 |
CDS | 108..629 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCTGACC GGGCTGCTGC CGAAAGGGCC TGCAAGGATC CCAATCCCAT CATTGATGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu78055 | |
Clone ID Related Accession (Same CDS sequence) | XM_011514388.2 | |
Accession Version | XM_011514388.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 465bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | RNA-binding protein 24 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011514388.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACGTCGT TTCTCCTGGC ACTGGGAAAC ATCTACAAGT CTGAGATAAA CAAGCTGGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011512690.1 |
CDS | 490..954 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGACGTCGT TTCTCCTGGC ACTGGGAAAC ATCTACAAGT CTGAGATAAA CAAGCTGGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu78056 | |
Clone ID Related Accession (Same CDS sequence) | XM_011514389.2 | |
Accession Version | XM_011514389.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 420bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | RNA-binding protein 24 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011514389.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACGTCGT TTCTCCTGGC ACTGGGAAAC ATCTACAAGT CTGGATACCT GCCCACTATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011512691.1 |
CDS | 484..903 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGACGTCGT TTCTCCTGGC ACTGGGAAAC ATCTACAAGT CTGGATACCT GCCCACTATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Rbm24, a target of p53, is necessary for proper expression of p53 and heart development. |
Global profiling of Rbm24 bound RNAs uncovers a multi-tasking RNA binding protein. |