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KLHL41 cDNA ORF clone, Mus musculus(House mouse)

Gene Symbol KLHL41
Entrez Gene ID 228003
Full Name kelch-like 41
Synonyms Gm112,Kbtbd10,SARCOSIN
General protein information
Preferred Names

kelch-like 41

Names

kelch-like protein 41
kelch repeat and BTB (POZ) domain containing 10
kelch repeat and BTB domain-containing protein 10

Gene Type protein-coding
Organism Mus musculus(House mouse)
Genome

2

2|2 C2


mRNA and Protein(s)

mRNA Protein Name
NM_001081087.1 NP_001074556.1 kelch-like protein 41



Homo sapiens (human) KLHL41 NP_006054.2
Canis lupus familiaris (dog) KLHL41 XP_535949.1
Gallus gallus (chicken) KBTBD10 XP_422010.1
Xenopus tropicalis (tropical clawed frog) klhl41 NP_989214.1
Mus musculus (house mouse) Klhl41 NP_001074556.1
Danio rerio (zebrafish) klhl41a XP_001922967.1
Pan troglodytes (chimpanzee) KBTBD10 XP_001135383.1
Danio rerio (zebrafish) klhl41b NP_945330.1
Macaca mulatta (rhesus monkey) KBTBD10 XP_001104263.1
Rattus norvegicus (Norway rat) Klhl41 NP_476539.1
Bos taurus (cattle) KBTBD10 NP_001076846.1


Related articles in PubMed

Identification of KLHL41 Mutations Implicates BTB-Kelch-Mediated Ubiquitination as an Alternate Pathway to Myofibrillar Disruption in Nemaline Myopathy.
Gupta VA, Ravenscroft G, Shaheen R, Todd EJ, Swanson LC, Shiina M, Ogata K, Hsu C, Clarke NF, Darras BT, Farrar MA, Hashem A, Manton ND, Muntoni F, North KN, Sandaradura SA, Nishino I, Hayashi YK, Sewry CA, Thompson EM, Yau KS, Brownstein CA, Yu TW, Allcock RJ, Davis MR, Wallgren-Pettersson C, Matsumoto N, Alkuraya FS, Laing NG, Beggs AH
American journal of human genetics93(6)1108-17(2013 Dec)

Sarcosin (Krp1) in skeletal muscle differentiation: gene expression profiling and knockdown experiments.
du Puy L, Beqqali A, van Tol HT, Monshouwer-Kloots J, Passier R, Haagsman HP, Roelen BA
The International journal of developmental biology56(4)301-9(2012)

BTB-Kelch protein Krp1 regulates proliferation and differentiation of myoblasts.
Paxton CW, Cosgrove RA, Drozd AC, Wiggins EL, Woodhouse S, Watson RA, Spence HJ, Ozanne BW, Pell JM
American journal of physiology. Cell physiology300(6)C1345-55(2011 Jun)

Krp1 (Sarcosin) promotes lateral fusion of myofibril assembly intermediates in cultured mouse cardiomyocytes.
Greenberg CC, Connelly PS, Daniels MP, Horowits R
Experimental cell research314(5)1177-91(2008 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data show that Sarcosin (Krp1) mRNA is expressed in the myotome part of the mature somites in mouse embryos from embryonic day 9.5 onwards.
Title: Sarcosin (Krp1) in skeletal muscle differentiation: gene expression profiling and knockdown experiments.

Krp1 promotes lateral fusion of adjacent thin fibrils into mature, wide myofibrils and contribute insight into mechanisms of myofibrillogenesis and disassembly
Title: Krp1 (Sarcosin) promotes lateral fusion of myofibril assembly intermediates in cultured mouse cardiomyocytes.

The following KLHL41 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KLHL41 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OMu01679 NM_001081087.1
Latest version!
Mus musculus kelch-like 41 (Klhl41), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $356.30
$509.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OMu01679
Clone ID Related Accession (Same CDS sequence) NM_001081087.1
Accession Version NM_001081087.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1821bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-29
Organism Mus musculus(House mouse)
Product kelch-like protein 41
Comment PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL929083.8. On Feb 6, 2007 this sequence version replaced XM_130293.6. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660811.30948.1, BC150698.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849384 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
ATGGATTCCC AGCGGGAGCT TGCAGAGGAA CTCCGGCTTT ACCAATCCAC CCTTCTTCAG 
GATGGTCTAA AAGATCTCCT GGAAGAGAAA AAGTTCATCG ATTGCACCCT AAAAGCAGGT
GACAAAAGTT TTCCTTGCCA CAGACTGATA CTATCGGCTT GTAGCCCTTA CTTCCGTGAG
TATTTTTTAT CTGAAATTGA GGAGGAGAAA AAAAAGGAGG TAGCCCTAGA CAACGTGGAT
CCTGCTATAC TTGATTTAAT CATCAAATAT CTGTACTCTG CCAGTATCGA TCTCAATGAT
GGGAATGTGC AAGACATCTT CGCCCTGTCC AGCCGCTTCC AGATTCCGTC GGTGTTCACC
GTCTGTGTGT CTTACCTTCA GAAAAGACTG GCTCCCGGTA ACTGTCTGGC CATCCTAAGA
TTGGGGCTGC TTCTCGACTG CCCGAGACTT GCCATTTCTG CCCGGGAGTT TGTGTCTGAT
CGCTTTGTGC AGATTTGTAA GGAAGAAGAT TTCATGCAAC TGTCCCCACA AGAACTGATC
TCCGTCATTT CAAACGACAG CCTCAACGTA GAAAAGGAGG AAGTAGTATT TGAGGCCGTG
ATGAAATGGG TGCGGACAGA CAAAGAAAAC AGGGCAAAAA ATCTTAGTGA GGTGTTTGAC
TGTATTCGTT TTCGCCTTAT GGCAGAGAAA TATTTCAAAG ATCATGTCGA GAAAGATGAC
ATAATTAAAA GCAACCCAGA AGTCCAGAAA AAAATCAAAG TTCTAAAAGA CGCTTTTGCA
GGCAAACTTC CGGAACCCAG CAAAAATGCA GAGAAGGCAG GGGCGGGCGA GGTGAACGGC
GATGTTGGTG ATGAAGACTT ACTTCCCGGT TACCTGAACG ATATCCCCAG GCATGGAATG
TTTGTTAAAG ATCTCATCCT CTTGGTCAAT GACACGGCTG CAGTAGCGTA TGACCCCATG
GAAAATGAGT GCTACCTTAC TGCCCTGGCA GAGCAGATCC CCAGAAACCA TTCCAGTCTT
GTTACCCAAC AGAATCAGGT CTACGTGGTC GGGGGACTGT ATGTGGACGA AGAAAATAAG
GATCAACCCC TGCAATCGTA CTTTTTCCAG CTTGATAACG TAACATCTGA GTGGGTCGGA
CTTCCGCCTC TCCCATCAGC CAGGTGTCTC TTTGGCCTGG GAGAAGTAGA TGACAAAATC
TATGTGGTGG CCGGCAAAGA CCTTCAAACA GAGGCCTCAC TGGATTCCGT GCTATGCTAC
GATCCTGTGG CTGCAAAGTG GAGTGAAGTG AAAAATCTTC CTATTAAAGT TTATGGCCAT
AATGTGATTT CACACAATGG GATGATATAC TGTCTAGGCG GAAAGACAGA TGACAAAAAG
TGTACAAATA GGGTATTTAT CTACAACCCC AAGAAAGGAG ACTGGAAAGA TCTGGCTCCG
ATGAAAACCC CTCGTTCCAT GTTTGGCGTG GCAATCCATA AAGGCAAGAT TGTGATCGCA
GGAGGTGTCA CTGAAGATGG TCTTTCAGCT TCAGTTGAAG CCTTTGACCT CAAAACCAAT
AAGTGGGAAG TGATGACGGA ATTTCCCCAA GAAAGAAGTT CTATCAGCCT GGTGAGCCTG
GCGGGAGCCC TGTACGCCAT CGGTGGCTTT GCGATGATCC AGCTGGAATC TAAAGAGTTT
GCACCCACTG AAGTCAATGA CATATGGAAG TATGAAGATG ATAAAAAAGA ATGGGCTGGG
ATGCTGAAGG AAATCCGTTA CGCTTCGGGA GCTAGTTGCC TAGCAACGCG CTTAAATCTG
TTTAAACTGT CTAAACTATA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001074556.1
CDS78..1898
Misc Feature(1)12..14
Misc Feature(2)84..86
Misc Feature(3)144..458
Misc Feature(4)192..1811
Misc Feature(5)516..788
Misc Feature(6)order(549..554,573..578,588..590,603..608,612..617,621..629,633..638)
Misc Feature(7)1080..1229
Misc Feature(8)1113..1271
Misc Feature(9)1113..1271
Misc Feature(10)1236..1379
Misc Feature(11)1239..1376
Misc Feature(12)1272..1418
Misc Feature(13)1386..1523
Misc Feature(14)1392..1532
Misc Feature(15)1419..1562
Misc Feature(16)1527..1664
Misc Feature(17)1530..1667
Misc Feature(18)1566..1703
Misc Feature(19)1707..1874
Exon (1)1..1187
Exon (2)1188..1345
Exon (3)1346..1453
Exon (4)1454..1639
Exon (5)1640..1786
Exon (6)1787..2538
Translation

Target ORF information:

RefSeq Version NM_001081087.1
Organism Mus musculus(House mouse)
Definition Mus musculus kelch-like 41 (Klhl41), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001081087.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
ATGGATTCCC AGCGGGAGCT TGCAGAGGAA CTCCGGCTTT ACCAATCCAC CCTTCTTCAG 
GATGGTCTAA AAGATCTCCT GGAAGAGAAA AAGTTCATCG ATTGCACCCT AAAAGCAGGT
GACAAAAGTT TTCCTTGCCA CAGACTGATA CTATCGGCTT GTAGCCCTTA CTTCCGTGAG
TATTTTTTAT CTGAAATTGA GGAGGAGAAA AAAAAGGAGG TAGCCCTAGA CAACGTGGAT
CCTGCTATAC TTGATTTAAT CATCAAATAT CTGTACTCTG CCAGTATCGA TCTCAATGAT
GGGAATGTGC AAGACATCTT CGCCCTGTCC AGCCGCTTCC AGATTCCGTC GGTGTTCACC
GTCTGTGTGT CTTACCTTCA GAAAAGACTG GCTCCCGGTA ACTGTCTGGC CATCCTAAGA
TTGGGGCTGC TTCTCGACTG CCCGAGACTT GCCATTTCTG CCCGGGAGTT TGTGTCTGAT
CGCTTTGTGC AGATTTGTAA GGAAGAAGAT TTCATGCAAC TGTCCCCACA AGAACTGATC
TCCGTCATTT CAAACGACAG CCTCAACGTA GAAAAGGAGG AAGTAGTATT TGAGGCCGTG
ATGAAATGGG TGCGGACAGA CAAAGAAAAC AGGGCAAAAA ATCTTAGTGA GGTGTTTGAC
TGTATTCGTT TTCGCCTTAT GGCAGAGAAA TATTTCAAAG ATCATGTCGA GAAAGATGAC
ATAATTAAAA GCAACCCAGA AGTCCAGAAA AAAATCAAAG TTCTAAAAGA CGCTTTTGCA
GGCAAACTTC CGGAACCCAG CAAAAATGCA GAGAAGGCAG GGGCGGGCGA GGTGAACGGC
GATGTTGGTG ATGAAGACTT ACTTCCCGGT TACCTGAACG ATATCCCCAG GCATGGAATG
TTTGTTAAAG ATCTCATCCT CTTGGTCAAT GACACGGCTG CAGTAGCGTA TGACCCCATG
GAAAATGAGT GCTACCTTAC TGCCCTGGCA GAGCAGATCC CCAGAAACCA TTCCAGTCTT
GTTACCCAAC AGAATCAGGT CTACGTGGTC GGGGGACTGT ATGTGGACGA AGAAAATAAG
GATCAACCCC TGCAATCGTA CTTTTTCCAG CTTGATAACG TAACATCTGA GTGGGTCGGA
CTTCCGCCTC TCCCATCAGC CAGGTGTCTC TTTGGCCTGG GAGAAGTAGA TGACAAAATC
TATGTGGTGG CCGGCAAAGA CCTTCAAACA GAGGCCTCAC TGGATTCCGT GCTATGCTAC
GATCCTGTGG CTGCAAAGTG GAGTGAAGTG AAAAATCTTC CTATTAAAGT TTATGGCCAT
AATGTGATTT CACACAATGG GATGATATAC TGTCTAGGCG GAAAGACAGA TGACAAAAAG
TGTACAAATA GGGTATTTAT CTACAACCCC AAGAAAGGAG ACTGGAAAGA TCTGGCTCCG
ATGAAAACCC CTCGTTCCAT GTTTGGCGTG GCAATCCATA AAGGCAAGAT TGTGATCGCA
GGAGGTGTCA CTGAAGATGG TCTTTCAGCT TCAGTTGAAG CCTTTGACCT CAAAACCAAT
AAGTGGGAAG TGATGACGGA ATTTCCCCAA GAAAGAAGTT CTATCAGCCT GGTGAGCCTG
GCGGGAGCCC TGTACGCCAT CGGTGGCTTT GCGATGATCC AGCTGGAATC TAAAGAGTTT
GCACCCACTG AAGTCAATGA CATATGGAAG TATGAAGATG ATAAAAAAGA ATGGGCTGGG
ATGCTGAAGG AAATCCGTTA CGCTTCGGGA GCTAGTTGCC TAGCAACGCG CTTAAATCTG
TTTAAACTGT CTAAACTATA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Identification of KLHL41 Mutations Implicates BTB-Kelch-Mediated Ubiquitination as an Alternate Pathway to Myofibrillar Disruption in Nemaline Myopathy.
American journal of human genetics93(6)1108-17(2013 Dec)
Gupta VA,Ravenscroft G,Shaheen R,Todd EJ,Swanson LC,Shiina M,Ogata K,Hsu C,Clarke NF,Darras BT,Farrar MA,Hashem A,Manton ND,Muntoni F,North KN,Sandaradura SA,Nishino I,Hayashi YK,Sewry CA,Thompson EM,Yau KS,Brownstein CA,Yu TW,Allcock RJ,Davis MR,Wallgren-Pettersson C,Matsumoto N,Alkuraya FS,Laing NG,Beggs AH


book

Sarcosin (Krp1) in skeletal muscle differentiation: gene expression profiling and knockdown experiments.
The International journal of developmental biology56(4)301-9(2012)
du Puy L,Beqqali A,van Tol HT,Monshouwer-Kloots J,Passier R,Haagsman HP,Roelen BA


book

BTB-Kelch protein Krp1 regulates proliferation and differentiation of myoblasts.
American journal of physiology. Cell physiology300(6)C1345-55(2011 Jun)
Paxton CW,Cosgrove RA,Drozd AC,Wiggins EL,Woodhouse S,Watson RA,Spence HJ,Ozanne BW,Pell JM


book

Krp1 (Sarcosin) promotes lateral fusion of myofibril assembly intermediates in cultured mouse cardiomyocytes.
Experimental cell research314(5)1177-91(2008 Mar)
Greenberg CC,Connelly PS,Daniels MP,Horowits R


 
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