Cyp51 cDNA ORF clone, Rattus norvegicus(Norway rat)
| Gene Symbol | Cyp51 |
| Entrez Gene ID | 25427 |
| Full Name | cytochrome P450, family 51 |
| Synonyms | Cyp51a1,RATCP14DM |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome | |
| Summary | gene amplification is detected in some endometrial carcinomas [RGD, Feb 2006]. |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_012941.2 | NP_037073.1 | lanosterol 14-alpha demethylase |
| Rattus norvegicus (Norway rat) | Cyp51 | NP_037073.1 |
| Danio rerio (zebrafish) | cyp51 | NP_001001730.2 |
| Pan troglodytes (chimpanzee) | CYP51A1 | XP_001165634.2 |
| Bos taurus (cattle) | CYP51A1 | NP_001020490.1 |
| Mus musculus (house mouse) | Cyp51 | NP_064394.2 |
| Gallus gallus (chicken) | CYP51A1 | NP_001041542.1 |
| Homo sapiens (human) | CYP51A1 | NP_000777.1 |
| Eremothecium gossypii | AGOS_ADR162W | NP_984259.1 |
| Schizosaccharomyces pombe (fission yeast) | erg11 | NP_592990.1 |
| Canis lupus familiaris (dog) | CYP51A1 | XP_532457.3 |
| Saccharomyces cerevisiae (baker's yeast) | ERG11 | NP_011871.1 |
| Magnaporthe oryzae (rice blast fungus) | MGG_04628 | XP_003710875.1 |
| Arabidopsis thaliana (thale cress) | CYP51G1 | NP_172633.1 |
| Oryza sativa (rice) | Os11g0525200 | NP_001067991.1 |
| LOC703490 | XP_002803431.1 | |
| Kluyveromyces lactis | KLLA0E03653g | XP_454109.1 |
| Xenopus tropicalis (tropical clawed frog) | cyp51a1 | NP_001016194.1 |
Related articles in PubMed
Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion.
Tamboli IY, Barth E, Christian L, Siepmann M, Kumar S, Singh S, Tolksdorf K, Heneka MT, L?tjohann D, Wunderlich P, Walter J
The Journal of biological chemistry285(48)37405-14(2010 Nov)
Structural basis of human CYP51 inhibition by antifungal azoles.
Strushkevich N, Usanov SA, Park HW
Journal of molecular biology397(4)1067-78(2010 Apr)
Defining the membrane proteome of NK cells.
Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)
Defects of cholesterol biosynthesis.
Waterham HR
FEBS letters580(23)5442-9(2006 Oct)
Puerarin decreases serum total cholesterol and enhances thoracic aorta endothelial nitric oxide synthase expression in diet-induced hypercholesterolemic rats.
Yan LP, Chan SW, Chan AS, Chen SL, Ma XJ, Xu HX
Life sciences79(4)324-30(2006 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Follicular fluid meiosis-activating sterol (FF-MAS) is synthesized by cytochrome P450 lanosterol 14alpha-demethylase. The results described here call into question any role of FF-MAS as an obligatory mediator of LH activity on germinal vesicle breakdown.
Title: Meiosis-activating sterol synthesis in rat preovulatory follicle: is it involved in resumption of meiosis?
The following Cyp51 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cyp51 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa01387 | |
| Clone ID Related Accession (Same CDS sequence) | NM_012941.2 | |
| Accession Version | NM_012941.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1512bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-21 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | lanosterol 14-alpha demethylase | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC087033.1. On Dec 26, 2004 this sequence version replaced NM_012941.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC087033.1, AY724494.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGTACTGC TGGGCTTGCT GCAGTCAGGC GGCTCGGTGC TCGGGCAGGC GATGGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_037073.1 |
| CDS | 65..1576 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_012941.2 |
ORF Insert Sequence:
1 | ATGGTACTGC TGGGCTTGCT GCAGTCAGGC GGCTCGGTGC TCGGGCAGGC GATGGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion. |
|
Structural basis of human CYP51 inhibition by antifungal azoles. |
|
Defining the membrane proteome of NK cells. |
|
Defects of cholesterol biosynthesis. |
|
Puerarin decreases serum total cholesterol and enhances thoracic aorta endothelial nitric oxide synthase expression in diet-induced hypercholesterolemic rats. |