hes6 cDNA ORF clone, Danio rerio(zebrafish)
| Gene Symbol | hes6 |
| Entrez Gene ID | 373116 |
| Full Name | hes family bHLH transcription factor 6 |
| Synonyms | YF-30,her13.2 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Danio rerio(zebrafish) |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_194400.2 | NP_919381.2 | transcription cofactor HES-6 |
| Canis lupus familiaris (dog) | HES6 | XP_849016.2 |
| Danio rerio (zebrafish) | hes6 | NP_919381.2 |
| Xenopus tropicalis (tropical clawed frog) | hes6.1 | XP_002933393.1 |
| Homo sapiens (human) | HES6 | NP_061115.2 |
| Bos taurus (cattle) | HES6 | NP_001069417.1 |
| Mus musculus (house mouse) | Hes6 | NP_062352.1 |
| Rattus norvegicus (Norway rat) | Hes6 | NP_001013197.1 |
| Danio rerio (zebrafish) | her13 | NP_001017901.1 |
Related articles in PubMed
The kinetics in mathematical models on segmentation clock genes in zebrafish.
Chen KW, Liao KL, Shih CW
Journal of mathematical biology76(1-2)97-150(2018 Jan)
A novel inducible mutagenesis screen enables to isolate and clone both embryonic and adult zebrafish mutants.
Ma Z, Zhu P, Pang M, Guo L, Chang N, Zheng J, Zhu X, Gao C, Huang H, Cui Z, Xiong JW, Peng J, Chen J
Scientific reports7(1)10381(2017 Sep)
Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
the PT enhancer with the 3'UTR of hes6 responded to the inhibition of retinoic acid synthesis and fibroblast growth factor signaling in a manner similar to endogenous hes6.
Title: Posterior-anterior gradient of zebrafish hes6 expression in the presomitic mesoderm is established by the combinatorial functions of the downstream enhancer and 3'UTR.
hes6, the clock gene that does not oscillate, responds to negative feedback
Title: Modeling the zebrafish segmentation clock's gene regulatory network constrained by expression data suggests evolutionary transitions between oscillating and nonoscillating transcription.
Data define a network of Her/Hes dimers underlying transcriptional negative feedback within the zebrafish segmentation clock, where Her7 acts directly within the delayed negative feedback as a DNA-binding heterodimer with Hes6.
Title: The Her7 node modulates the network topology of the zebrafish segmentation clock via sequestration of the Hes6 hub.
Forms specific heterodimers with her1, which may directly be required for regulating further target genes.
Title: her1 and her13.2 are jointly required for somitic border specification along the entire axis of the fish embryo.
The following hes6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the hes6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ODa02495 | |
| Clone ID Related Accession (Same CDS sequence) | NM_194400.2 | |
| Accession Version | NM_194400.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 681bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-25 | |
| Organism | Danio rerio(zebrafish) | |
| Product | transcription cofactor HES-6 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC065599.1. On or before Jul 6, 2005 this sequence version replaced XM_685813.1, NM_194400.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC065599.1, AB158461.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGCCCCTG CGTCCCGCAG CAACACTCAC GACGAGGATA ATTACGGAAT AAAAGACAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_919381.2 |
| CDS | 83..763 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_194400.2 |
ORF Insert Sequence:
1 | ATGGCCCCTG CGTCCCGCAG CAACACTCAC GACGAGGATA ATTACGGAAT AAAAGACAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
The kinetics in mathematical models on segmentation clock genes in zebrafish. |
|
A novel inducible mutagenesis screen enables to isolate and clone both embryonic and adult zebrafish mutants. |
|
Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. |