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IL31 cDNA ORF clone, Homo sapiens(human)

Summary

Gene Symbol IL31
Entrez Gene ID 386653
Full Name interleukin 31
Synonyms IL-31
General protein information
Preferred Names

interleukin 31

Names

interleukin-31
Gene Type protein-coding
Organism Homo sapiens(human)
Genome

12

12q24.31
Summary IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM, Mar 2008].
Disorder MIM:

609509


Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_011538326.1 XP_011536628.1 interleukin-31 isoform X1
NM_001014336.1 NP_001014358.1 interleukin-31 precursor
NM_001014336.2 NP_001014358.1 interleukin-31 precursor

Pathways from BioSystems


Homologies


Pan troglodytes (chimpanzee) IL31 XP_001166732.1
Canis lupus familiaris (dog) IL31 NP_001159386.1
IL31 XP_001096743.1
Homo sapiens (human) IL31 NP_001014358.1

Gene Ontology

The following IL31 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IL31 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu24055 NM_001014336.2
Latest version!		 Homo sapiens interleukin 31 (IL31), mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK 		$49.50-$69.30
$99.00
OHu24055 XM_011538326.1
Latest version!		 Homo sapiens interleukin 31 (IL31), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK 		$49.50-$69.30
$99.00
View Old Accession Versions >>
OHu24055 NM_001014336.1 Homo sapiens interleukin 31 (IL31), mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK 		$49.50-$69.30
$99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu24055
Clone ID Related Accession (Same CDS sequence) XM_011538326.1 , NM_001014336.1 , NM_001014336.2
Accession Version NM_001014336.1 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 495bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-03-11
Organism Homo sapiens(human)
Product interleukin-31 precursor
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY499343.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY499343.1, BC132998.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2148093, SAMEA2148874 [ECO:0000350] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
ATGGCCTCTC ACTCAGGCCC CTCGACGTCT GTGCTCTTTC TGTTCTGCTG CCTGGGAGGC 
TGGCTGGCCT CCCACACGTT GCCCGTCCGT TTACTACGAC CAAGTGATGA TGTACAGAAA 
ATAGTCGAGG AATTACAGTC CCTCTCGAAG ATGCTTTTGA AAGATGTGGA GGAAGAGAAG 
GGCGTGCTCG TGTCCCAGAA TTACACGCTG CCGTGTCTCA GCCCTGACGC CCAGCCGCCA 
AACAACATCC ACAGCCCAGC CATCCGGGCA TATCTCAAGA CAATCAGACA GCTAGACAAC 
AAATCTGTTA TTGATGAGAT CATAGAGCAC CTCGACAAAC TCATATTTCA AGATGCACCA 
GAAACAAACA TTTCTGTGCC AACAGACACC CATGAATGTA AACGCTTCAT CCTGACTATT 
TCTCAACAGT TTTCAGAGTG CATGGACCTC GCACTAAAAT CATTGACCTC TGGAGCCCAA 
CAGGCCACCA CTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001014358.1
CDS28..522
Translation

Target ORF information:

RefSeq Version NM_001014336.1
Organism Homo sapiens(human)
Definition Homo sapiens interleukin 31 (IL31), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001014336.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGGCCTCTC ACTCAGGCCC CTCGACGTCT GTGCTCTTTC TGTTCTGCTG CCTGGGAGGC 
TGGCTGGCCT CCCACACGTT GCCCGTCCGT TTACTACGAC CAAGTGATGA TGTACAGAAA 
ATAGTCGAGG AATTACAGTC CCTCTCGAAG ATGCTTTTGA AAGATGTGGA GGAAGAGAAG 
GGCGTGCTCG TGTCCCAGAA TTACACGCTG CCGTGTCTCA GCCCTGACGC CCAGCCGCCA 
AACAACATCC ACAGCCCAGC CATCCGGGCA TATCTCAAGA CAATCAGACA GCTAGACAAC 
AAATCTGTTA TTGATGAGAT CATAGAGCAC CTCGACAAAC TCATATTTCA AGATGCACCA 
GAAACAAACA TTTCTGTGCC AACAGACACC CATGAATGTA AACGCTTCAT CCTGACTATT 
TCTCAACAGT TTTCAGAGTG CATGGACCTC GCACTAAAAT CATTGACCTC TGGAGCCCAA 
CAGGCCACCA CTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24055
Clone ID Related Accession (Same CDS sequence) XM_011538326.1 , NM_001014336.1 , NM_001014336.2
Accession Version NM_001014336.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 495bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2020-01-01
Organism Homo sapiens(human)
Product interleukin-31 precursor
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC048338.29 and AY499343.1. On May 17, 2019 this sequence version replaced NM_001014336.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY499343.1, BC132998.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2148093, SAMEA2148874 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000377035.2/ ENSP00000366234.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## 

1
61
121
181
241
301
361
421
481
ATGGCCTCTC ACTCAGGCCC CTCGACGTCT GTGCTCTTTC TGTTCTGCTG CCTGGGAGGC 
TGGCTGGCCT CCCACACGTT GCCCGTCCGT TTACTACGAC CAAGTGATGA TGTACAGAAA 
ATAGTCGAGG AATTACAGTC CCTCTCGAAG ATGCTTTTGA AAGATGTGGA GGAAGAGAAG 
GGCGTGCTCG TGTCCCAGAA TTACACGCTG CCGTGTCTCA GCCCTGACGC CCAGCCGCCA 
AACAACATCC ACAGCCCAGC CATCCGGGCA TATCTCAAGA CAATCAGACA GCTAGACAAC 
AAATCTGTTA TTGATGAGAT CATAGAGCAC CTCGACAAAC TCATATTTCA AGATGCACCA 
GAAACAAACA TTTCTGTGCC AACAGACACC CATGAATGTA AACGCTTCAT CCTGACTATT 
TCTCAACAGT TTTCAGAGTG CATGGACCTC GCACTAAAAT CATTGACCTC TGGAGCCCAA 
CAGGCCACCA CTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001014358.1
CDS50..544
Translation

Target ORF information:

RefSeq Version NM_001014336.2
Organism Homo sapiens(human)
Definition Homo sapiens interleukin 31 (IL31), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001014336.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGGCCTCTC ACTCAGGCCC CTCGACGTCT GTGCTCTTTC TGTTCTGCTG CCTGGGAGGC 
TGGCTGGCCT CCCACACGTT GCCCGTCCGT TTACTACGAC CAAGTGATGA TGTACAGAAA 
ATAGTCGAGG AATTACAGTC CCTCTCGAAG ATGCTTTTGA AAGATGTGGA GGAAGAGAAG 
GGCGTGCTCG TGTCCCAGAA TTACACGCTG CCGTGTCTCA GCCCTGACGC CCAGCCGCCA 
AACAACATCC ACAGCCCAGC CATCCGGGCA TATCTCAAGA CAATCAGACA GCTAGACAAC 
AAATCTGTTA TTGATGAGAT CATAGAGCAC CTCGACAAAC TCATATTTCA AGATGCACCA 
GAAACAAACA TTTCTGTGCC AACAGACACC CATGAATGTA AACGCTTCAT CCTGACTATT 
TCTCAACAGT TTTCAGAGTG CATGGACCTC GCACTAAAAT CATTGACCTC TGGAGCCCAA 
CAGGCCACCA CTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24055
Clone ID Related Accession (Same CDS sequence) XM_011538326.1 , NM_001014336.1 , NM_001014336.2
Accession Version XM_011538326.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 495bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2015-03-11
Organism Homo sapiens(Human)
Product interleukin-31 isoform X1
Comment 

1
61
121
181
241
301
361
421
481
ATGGCCTCTC ACTCAGGCCC CTCGACGTCT GTGCTCTTTC TGTTCTGCTG CCTGGGAGGC 
TGGCTGGCCT CCCACACGTT GCCCGTCCGT TTACTACGAC CAAGTGATGA TGTACAGAAA 
ATAGTCGAGG AATTACAGTC CCTCTCGAAG ATGCTTTTGA AAGATGTGGA GGAAGAGAAG 
GGCGTGCTCG TGTCCCAGAA TTACACGCTG CCGTGTCTCA GCCCTGACGC CCAGCCGCCA 
AACAACATCC ACAGCCCAGC CATCCGGGCA TATCTCAAGA CAATCAGACA GCTAGACAAC 
AAATCTGTTA TTGATGAGAT CATAGAGCAC CTCGACAAAC TCATATTTCA AGATGCACCA 
GAAACAAACA TTTCTGTGCC AACAGACACC CATGAATGTA AACGCTTCAT CCTGACTATT 
TCTCAACAGT TTTCAGAGTG CATGGACCTC GCACTAAAAT CATTGACCTC TGGAGCCCAA 
CAGGCCACCA CTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011536628.1
Translation

Target ORF information:

RefSeq Version XM_011538326.1
Organism Homo sapiens(Human)
Definition Homo sapiens interleukin 31 (IL31), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_011538326.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGGCCTCTC ACTCAGGCCC CTCGACGTCT GTGCTCTTTC TGTTCTGCTG CCTGGGAGGC 
TGGCTGGCCT CCCACACGTT GCCCGTCCGT TTACTACGAC CAAGTGATGA TGTACAGAAA 
ATAGTCGAGG AATTACAGTC CCTCTCGAAG ATGCTTTTGA AAGATGTGGA GGAAGAGAAG 
GGCGTGCTCG TGTCCCAGAA TTACACGCTG CCGTGTCTCA GCCCTGACGC CCAGCCGCCA 
AACAACATCC ACAGCCCAGC CATCCGGGCA TATCTCAAGA CAATCAGACA GCTAGACAAC 
AAATCTGTTA TTGATGAGAT CATAGAGCAC CTCGACAAAC TCATATTTCA AGATGCACCA 
GAAACAAACA TTTCTGTGCC AACAGACACC CATGAATGTA AACGCTTCAT CCTGACTATT 
TCTCAACAGT TTTCAGAGTG CATGGACCTC GCACTAAAAT CATTGACCTC TGGAGCCCAA 
CAGGCCACCA CTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed