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MGST3 cDNA ORF clone, Homo sapiens(Human)

Summary

Gene Symbol MGST3
Entrez Gene ID 4259
Full Name microsomal glutathione S-transferase 3
Synonyms GST-III
General protein information
Preferred Names

microsomal glutathione S-transferase 3

Names

microsomal glutathione S-transferase 3
microsomal GST-3
microsomal GST-III
microsomal glutathione S-transferase III
Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

1

1q24.1
Summary This gene encodes a member of the MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) protein family. Members of this family are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes an enzyme which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. This enzyme also demonstrates glutathione-dependent peroxidase activity towards lipid hydroperoxides.[provided by RefSeq, May 2011].
Disorder MIM:

604564


Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_004528.3 NP_004519.1 microsomal glutathione S-transferase 3
NM_004528.4 NP_004519.1 microsomal glutathione S-transferase 3
XM_005245174.3 XP_005245231.2 microsomal glutathione S-transferase 3 isoform X1
XM_005245174.2 XP_005245231.2 microsomal glutathione S-transferase 3 isoform X1

Pathways from BioSystems


Homologies


Mus musculus (house mouse) Mgst3 NP_079845.1
Gallus gallus (chicken) MGST3 NP_001264462.1
Danio rerio (zebrafish) mgst3 NP_998592.1
Pan troglodytes (chimpanzee) MGST3 XP_001174626.1
Bos taurus (cattle) MGST3 NP_001030218.1
Canis lupus familiaris (dog) MGST3 NP_001239339.1
Homo sapiens (human) MGST3 NP_004519.1
MGST3 XP_001085550.1
Oryza sativa (rice) Os03g0709000 NP_001051042.1
Rattus norvegicus (Norway rat) Mgst3 NP_001178523.1
Arabidopsis thaliana (thale cress) AT1G65820 NP_176758.1
Xenopus tropicalis (tropical clawed frog) mgst3 NP_001006890.1

Gene Ontology


Bibliography

Related articles in PubMed

Defining the membrane proteome of NK cells.
Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)

Subtractive hybridisation screen identifies genes regulated by glucose deprivation in human neuroblastoma cells.
Kobayashi K, Xin Y, Ymer SI, Werther GA, Russo VC
Brain research1170129-39(2007 Sep)

Evaluation of the microsomal glutathione S-transferase 3 (MGST3) locus on 1q23 as a Type 2 diabetes susceptibility gene in Pima Indians.
Thameem F, Yang X, Permana PA, Wolford JK, Bogardus C, Prochazka M
Human genetics113(4)353-8(2003 Sep)

Membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG). A widespread protein superfamily.
Jakobsson PJ, Morgenstern R, Mancini J, Ford-Hutchinson A, Persson B
American journal of respiratory and critical care medicine161(2 Pt 2)S20-4(2000 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

Observational study of gene-disease association. (HuGE Navigator)
Title: Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study.

Observational study of gene-disease association. (HuGE Navigator)
Title: Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.

Observational study of gene-disease association. (HuGE Navigator)
Title: Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation.

The following MGST3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MGST3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

Online Only Promotion

Up to 50% OFF! Starting
from $49/clone
***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu11138 NM_004528.4
Latest version!		 Homo sapiens microsomal glutathione S-transferase 3 (MGST3), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $49.50-$69.30
$99.00
OHu11138 XM_005245174.3
Latest version!		 Homo sapiens microsomal glutathione S-transferase 3 (MGST3), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $49.50-$69.30
$99.00
View Old Accession Versions >>
OHu11138 NM_004528.3 Homo sapiens microsomal glutathione S-transferase 3 (MGST3), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $49.50-$69.30
$99.00
OHu11138 XM_005245174.2 Homo sapiens microsomal glutathione S-transferase 3 (MGST3), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $49.50-$69.30
$99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu11138
Clone ID Related Accession (Same CDS sequence) NM_004528.3 , NM_004528.4 , XM_005245174.3 , XM_005245174.2
Accession Version NM_004528.3 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 459bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2017-10-01
Organism Homo sapiens(human)
Product microsomal glutathione S-transferase 3
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL356441.16, BC000505.2, AL451074.13 and AI591182.1. On May 3, 2011 this sequence version replaced NM_004528.2. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.277394.1, SRR1803616.162497.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
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421
ATGGCTGTCC TCTCTAAGGA ATATGGTTTT GTGCTTCTAA CTGGTGCTGC CAGCTTTATA 
ATGGTGGCCC ACCTAGCCAT CAATGTTTCC AAGGCCCGCA AGAAGTACAA AGTGGAGTAT 
CCTATCATGT ACAGCACGGA CCCTGAAAAT GGGCACATCT TCAACTGCAT TCAGCGAGCC 
CACCAGAACA CGTTGGAAGT GTATCCTCCC TTCTTATTTT TTCTAGCTGT TGGAGGTGTT 
TACCACCCGC GTATAGCTTC TGGCCTGGGC TTGGCCTGGA TTGTTGGACG AGTTCTTTAT 
GCTTATGGCT ATTACACGGG AGAACCCAGC AAGCGTAGTC GAGGAGCCCT GGGGTCCATC 
GCCCTCCTGG GCTTGGTGGG CACAACTGTG TGCTCTGCTT TCCAGCATCT TGGTTGGGTT 
AAAAGTGGCT TGGGCAGTGG ACCCAAATGC TGCCATTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_004519.1
CDS429..887
Translation

Target ORF information:

RefSeq Version NM_004528.3
Organism Homo sapiens(human)
Definition Homo sapiens microsomal glutathione S-transferase 3 (MGST3), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_004528.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGCTGTCC TCTCTAAGGA ATATGGTTTT GTGCTTCTAA CTGGTGCTGC CAGCTTTATA 
ATGGTGGCCC ACCTAGCCAT CAATGTTTCC AAGGCCCGCA AGAAGTACAA AGTGGAGTAT 
CCTATCATGT ACAGCACGGA CCCTGAAAAT GGGCACATCT TCAACTGCAT TCAGCGAGCC 
CACCAGAACA CGTTGGAAGT GTATCCTCCC TTCTTATTTT TTCTAGCTGT TGGAGGTGTT 
TACCACCCGC GTATAGCTTC TGGCCTGGGC TTGGCCTGGA TTGTTGGACG AGTTCTTTAT 
GCTTATGGCT ATTACACGGG AGAACCCAGC AAGCGTAGTC GAGGAGCCCT GGGGTCCATC 
GCCCTCCTGG GCTTGGTGGG CACAACTGTG TGCTCTGCTT TCCAGCATCT TGGTTGGGTT 
AAAAGTGGCT TGGGCAGTGG ACCCAAATGC TGCCATTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu11138
Clone ID Related Accession (Same CDS sequence) NM_004528.3 , NM_004528.4 , XM_005245174.3 , XM_005245174.2
Accession Version NM_004528.4 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 459bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-09-24
Organism Homo sapiens(human)
Product microsomal glutathione S-transferase 3
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL356441.16, BC000505.2, AL451074.13 and AI591182.1. On Nov 22, 2018 this sequence version replaced NM_004528.3. ##Evidence-Data-START## Transcript exon combination :: SRR5189652.128769.1, SRR1803617.277394.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000367889.8/ ENSP00000356864.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. 

1
61
121
181
241
301
361
421
ATGGCTGTCC TCTCTAAGGA ATATGGTTTT GTGCTTCTAA CTGGTGCTGC CAGCTTTATA 
ATGGTGGCCC ACCTAGCCAT CAATGTTTCC AAGGCCCGCA AGAAGTACAA AGTGGAGTAT 
CCTATCATGT ACAGCACGGA CCCTGAAAAT GGGCACATCT TCAACTGCAT TCAGCGAGCC 
CACCAGAACA CGTTGGAAGT GTATCCTCCC TTCTTATTTT TTCTAGCTGT TGGAGGTGTT 
TACCACCCGC GTATAGCTTC TGGCCTGGGC TTGGCCTGGA TTGTTGGACG AGTTCTTTAT 
GCTTATGGCT ATTACACGGG AGAACCCAGC AAGCGTAGTC GAGGAGCCCT GGGGTCCATC 
GCCCTCCTGG GCTTGGTGGG CACAACTGTG TGCTCTGCTT TCCAGCATCT TGGTTGGGTT 
AAAAGTGGCT TGGGCAGTGG ACCCAAATGC TGCCATTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_004519.1
CDS68..526
Translation

Target ORF information:

RefSeq Version NM_004528.4
Organism Homo sapiens(human)
Definition Homo sapiens microsomal glutathione S-transferase 3 (MGST3), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_004528.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGCTGTCC TCTCTAAGGA ATATGGTTTT GTGCTTCTAA CTGGTGCTGC CAGCTTTATA 
ATGGTGGCCC ACCTAGCCAT CAATGTTTCC AAGGCCCGCA AGAAGTACAA AGTGGAGTAT 
CCTATCATGT ACAGCACGGA CCCTGAAAAT GGGCACATCT TCAACTGCAT TCAGCGAGCC 
CACCAGAACA CGTTGGAAGT GTATCCTCCC TTCTTATTTT TTCTAGCTGT TGGAGGTGTT 
TACCACCCGC GTATAGCTTC TGGCCTGGGC TTGGCCTGGA TTGTTGGACG AGTTCTTTAT 
GCTTATGGCT ATTACACGGG AGAACCCAGC AAGCGTAGTC GAGGAGCCCT GGGGTCCATC 
GCCCTCCTGG GCTTGGTGGG CACAACTGTG TGCTCTGCTT TCCAGCATCT TGGTTGGGTT 
AAAAGTGGCT TGGGCAGTGG ACCCAAATGC TGCCATTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu11138
Clone ID Related Accession (Same CDS sequence) NM_004528.3 , NM_004528.4 , XM_005245174.3 , XM_005245174.2
Accession Version XM_005245174.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 459bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-05
Organism Homo sapiens(human)
Product microsomal glutathione S-transferase 3 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005245174.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
ATGGCTGTCC TCTCTAAGGA ATATGGTTTT GTGCTTCTAA CTGGTGCTGC CAGCTTTATA 
ATGGTGGCCC ACCTAGCCAT CAATGTTTCC AAGGCCCGCA AGAAGTACAA AGTGGAGTAT 
CCTATCATGT ACAGCACGGA CCCTGAAAAT GGGCACATCT TCAACTGCAT TCAGCGAGCC 
CACCAGAACA CGTTGGAAGT GTATCCTCCC TTCTTATTTT TTCTAGCTGT TGGAGGTGTT 
TACCACCCGC GTATAGCTTC TGGCCTGGGC TTGGCCTGGA TTGTTGGACG AGTTCTTTAT 
GCTTATGGCT ATTACACGGG AGAACCCAGC AAGCGTAGTC GAGGAGCCCT GGGGTCCATC 
GCCCTCCTGG GCTTGGTGGG CACAACTGTG TGCTCTGCTT TCCAGCATCT TGGTTGGGTT 
AAAAGTGGCT TGGGCAGTGG ACCCAAATGC TGCCATTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005245231.2
CDS32..490
Translation

Target ORF information:

RefSeq Version XM_005245174.3
Organism Homo sapiens(human)
Definition Homo sapiens microsomal glutathione S-transferase 3 (MGST3), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_005245174.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGCTGTCC TCTCTAAGGA ATATGGTTTT GTGCTTCTAA CTGGTGCTGC CAGCTTTATA 
ATGGTGGCCC ACCTAGCCAT CAATGTTTCC AAGGCCCGCA AGAAGTACAA AGTGGAGTAT 
CCTATCATGT ACAGCACGGA CCCTGAAAAT GGGCACATCT TCAACTGCAT TCAGCGAGCC 
CACCAGAACA CGTTGGAAGT GTATCCTCCC TTCTTATTTT TTCTAGCTGT TGGAGGTGTT 
TACCACCCGC GTATAGCTTC TGGCCTGGGC TTGGCCTGGA TTGTTGGACG AGTTCTTTAT 
GCTTATGGCT ATTACACGGG AGAACCCAGC AAGCGTAGTC GAGGAGCCCT GGGGTCCATC 
GCCCTCCTGG GCTTGGTGGG CACAACTGTG TGCTCTGCTT TCCAGCATCT TGGTTGGGTT 
AAAAGTGGCT TGGGCAGTGG ACCCAAATGC TGCCATTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu11138
Clone ID Related Accession (Same CDS sequence) NM_004528.3 , NM_004528.4 , XM_005245174.3 , XM_005245174.2
Accession Version XM_005245174.2 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 459bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2015-03-11
Organism Homo sapiens(Human)
Product microsomal glutathione S-transferase 3 isoform X1
Comment 

1
61
121
181
241
301
361
421
ATGGCTGTCC TCTCTAAGGA ATATGGTTTT GTGCTTCTAA CTGGTGCTGC CAGCTTTATA 
ATGGTGGCCC ACCTAGCCAT CAATGTTTCC AAGGCCCGCA AGAAGTACAA AGTGGAGTAT 
CCTATCATGT ACAGCACGGA CCCTGAAAAT GGGCACATCT TCAACTGCAT TCAGCGAGCC 
CACCAGAACA CGTTGGAAGT GTATCCTCCC TTCTTATTTT TTCTAGCTGT TGGAGGTGTT 
TACCACCCGC GTATAGCTTC TGGCCTGGGC TTGGCCTGGA TTGTTGGACG AGTTCTTTAT 
GCTTATGGCT ATTACACGGG AGAACCCAGC AAGCGTAGTC GAGGAGCCCT GGGGTCCATC 
GCCCTCCTGG GCTTGGTGGG CACAACTGTG TGCTCTGCTT TCCAGCATCT TGGTTGGGTT 
AAAAGTGGCT TGGGCAGTGG ACCCAAATGC TGCCATTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005245231.2
Translation

Target ORF information:

RefSeq Version XM_005245174.2
Organism Homo sapiens(Human)
Definition Homo sapiens microsomal glutathione S-transferase 3 (MGST3), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_005245174.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGCTGTCC TCTCTAAGGA ATATGGTTTT GTGCTTCTAA CTGGTGCTGC CAGCTTTATA 
ATGGTGGCCC ACCTAGCCAT CAATGTTTCC AAGGCCCGCA AGAAGTACAA AGTGGAGTAT 
CCTATCATGT ACAGCACGGA CCCTGAAAAT GGGCACATCT TCAACTGCAT TCAGCGAGCC 
CACCAGAACA CGTTGGAAGT GTATCCTCCC TTCTTATTTT TTCTAGCTGT TGGAGGTGTT 
TACCACCCGC GTATAGCTTC TGGCCTGGGC TTGGCCTGGA TTGTTGGACG AGTTCTTTAT 
GCTTATGGCT ATTACACGGG AGAACCCAGC AAGCGTAGTC GAGGAGCCCT GGGGTCCATC 
GCCCTCCTGG GCTTGGTGGG CACAACTGTG TGCTCTGCTT TCCAGCATCT TGGTTGGGTT 
AAAAGTGGCT TGGGCAGTGG ACCCAAATGC TGCCATTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Defining the membrane proteome of NK cells.
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)
Ghosh D,Lippert D,Krokhin O,Cortens JP,Wilkins JA


book

Subtractive hybridisation screen identifies genes regulated by glucose deprivation in human neuroblastoma cells.
Brain research1170129-39(2007 Sep)
Kobayashi K,Xin Y,Ymer SI,Werther GA,Russo VC


book

Evaluation of the microsomal glutathione S-transferase 3 (MGST3) locus on 1q23 as a Type 2 diabetes susceptibility gene in Pima Indians.
Human genetics113(4)353-8(2003 Sep)
Thameem F,Yang X,Permana PA,Wolford JK,Bogardus C,Prochazka M


book

Membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG). A widespread protein superfamily.
American journal of respiratory and critical care medicine161(2 Pt 2)S20-4(2000 Feb)
Jakobsson PJ,Morgenstern R,Mancini J,Ford-Hutchinson A,Persson B