Gene Symbol | KANSL2 |
Entrez Gene ID | 54934 |
Full Name | KAT8 regulatory NSL complex subunit 2 |
Synonyms | C12orf41,NSL2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » KANSL2 cDNA ORF clone
gRNAs
Gene Symbol | KANSL2 |
Entrez Gene ID | 54934 |
Full Name | KAT8 regulatory NSL complex subunit 2 |
Synonyms | C12orf41,NSL2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_017822.3 | NP_060292.3 | KAT8 regulatory NSL complex subunit 2 |
NM_017822.4 | NP_060292.3 | KAT8 regulatory NSL complex subunit 2 |
Homo sapiens (human) | KANSL2 | NP_060292.3 |
Mus musculus (house mouse) | Kansl2 | NP_598475.2 |
Xenopus tropicalis (tropical clawed frog) | kansl2 | NP_001096493.1 |
Pan troglodytes (chimpanzee) | KANSL2 | XP_509031.4 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP006680 | XP_316718.4 |
LOC709517 | XP_001098054.2 | |
Bos taurus (cattle) | KANSL2 | NP_001019742.2 |
Rattus norvegicus (Norway rat) | Kansl2 | NP_001004244.2 |
Gallus gallus (chicken) | KANSL2 | XP_004950485.1 |
Canis lupus familiaris (dog) | KANSL2 | XP_005636954.1 |
Danio rerio (zebrafish) | kansl2 | NP_001005990.1 |
Drosophila melanogaster (fruit fly) | dgt1 | NP_651737.1 |
A High-Density Map for Navigating the Human Polycomb Complexome.
Hauri S, Comoglio F, Seimiya M, Gerstung M, Glatter T, Hansen K, Aebersold R, Paro R, Gstaiger M, Beisel C
Cell reports17(2)583-595(2016 10)
The NSL Chromatin-Modifying Complex Subunit KANSL2 Regulates Cancer Stem-like Properties in Glioblastoma That Contribute to Tumorigenesis.
Ferreyra Solari NE, Belforte FS, Canedo L, Videla-Richardson GA, Espinosa JM, Rossi M, Serna E, Riudavets MA, Martinetto H, Sevlever G, Perez-Castro C
Cancer research76(18)5383-94(2016 Sep)
Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.
Goldstein JI, Jarskog LF, Hilliard C, Alfirevic A, Duncan L, Fourches D, Huang H, Lek M, Neale BM, Ripke S, Shianna K, Szatkiewicz JP, Tropsha A, van den Oord EJ, Cascorbi I, Dettling M, Gazit E, Goff DC, Holden AL, Kelly DL, Malhotra AK, Nielsen J, Pirmohamed M, Rujescu D, Werge T, Levy DL, Josiassen RC, Kennedy JL, Lieberman JA, Daly MJ, Sullivan PF
Nature communications54757(2014 Sep)
Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complex.
Dias J, Van Nguyen N, Georgiev P, Gaub A, Brettschneider J, Cusack S, Kadlec J, Akhtar A
Genes & development28(9)929-42(2014 May)
Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex.
Cai Y, Jin J, Swanson SK, Cole MD, Choi SH, Florens L, Washburn MP, Conaway JW, Conaway RC
The Journal of biological chemistry285(7)4268-72(2010 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
our findings indicate that KANSL2 acts to regulate the stem cell population in glioblastoma
Title: The NSL Chromatin-Modifying Complex Subunit KANSL2 Regulates Cancer Stem-like Properties in Glioblastoma That Contribute to Tumorigenesis.
The following KANSL2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KANSL2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu31070![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_017822.3 , NM_017822.4 | |
Accession Version | NM_017822.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1479bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-17 | |
Organism | Homo sapiens(human) | |
Product | KAT8 regulatory NSL complex subunit 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA278834.1, BC009746.2, BG760446.1 and BM672156.1. On Aug 2, 2007 this sequence version replaced NM_017822.2. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.140524.1, SRR1803616.209831.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGAACAGGA TTCGGATTCA CGTCTTGCCA ACCAATCGGG GGAGGATCAC TCCAGTGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_060292.3 |
CDS | 76..1554 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGAACAGGA TTCGGATTCA CGTCTTGCCA ACCAATCGGG GGAGGATCAC TCCAGTGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu31070![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_017822.3 , NM_017822.4 | |
Accession Version | NM_017822.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1479bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-07-09 | |
Organism | Homo sapiens(human) | |
Product | KAT8 regulatory NSL complex subunit 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA278834.1, BC009746.2, BG760446.1 and BM672156.1. On Jun 2, 2019 this sequence version replaced NM_017822.3. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.61942.1, SRR1803615.50506.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. |
1 | ATGAACAGGA TTCGGATTCA CGTCTTGCCA ACCAATCGGG GGAGGATCAC TCCAGTGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_060292.3 |
CDS | 62..1540 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGAACAGGA TTCGGATTCA CGTCTTGCCA ACCAATCGGG GGAGGATCAC TCCAGTGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
A High-Density Map for Navigating the Human Polycomb Complexome. |
The NSL Chromatin-Modifying Complex Subunit KANSL2 Regulates Cancer Stem-like Properties in Glioblastoma That Contribute to Tumorigenesis. |
Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles. |
Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complex. |
Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex. |