| Gene Symbol | FGD6 |
| Entrez Gene ID | 55785 |
| Full Name | FYVE, RhoGEF and PH domain containing 6 |
| Synonyms | ZFYVE24 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Disorder MIM: |
gRNAs
The following FGD6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FGD6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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| CloneID | OHu08865 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_018351.3 , NM_018351.4 | |
| Accession Version | NM_018351.3 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 4293bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-10-01 | |
| Organism | Homo sapiens(human) | |
| Product | FYVE, RhoGEF and PH domain-containing protein 6 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK124904.1, AK128492.1 and AC011598.33. On Jul 31, 2007 this sequence version replaced NM_018351.2. ##Evidence-Data-START## Transcript exon combination :: AK124904.1, SRR1660805.108148.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGACTTCTG CAGCCGAGAT AAAGAAGCCA CCAGTGGCCC CCAAGCCCAA GTTTGTTGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_060821.3 |
| CDS | 225..4517 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_018351.3 |
1 | ATGACTTCTG CAGCCGAGAT AAAGAAGCCA CCAGTGGCCC CCAAGCCCAA GTTTGTTGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu08865 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_018351.3 , NM_018351.4 | |
| Accession Version | NM_018351.4 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 4293bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-30 | |
| Organism | Homo sapiens(human) | |
| Product | FYVE, RhoGEF and PH domain-containing protein 6 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC127165.4, AK124904.1, AK128492.1 and AC011598.33. On Nov 22, 2018 this sequence version replaced NM_018351.3. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.108148.1, SRR1803616.101532.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000343958.9/ ENSP00000344446.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length. | |
1 | ATGACTTCTG CAGCCGAGAT AAAGAAGCCA CCAGTGGCCC CCAAGCCCAA GTTTGTTGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_060821.3 |
| CDS | 228..4520 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_018351.4 |
1 | ATGACTTCTG CAGCCGAGAT AAAGAAGCCA CCAGTGGCCC CCAAGCCCAA GTTTGTTGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
A missense variant in FGD6 confers increased risk of polypoidal choroidal vasculopathy. |
Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. |
High-throughput mapping of a dynamic signaling network in mammalian cells. |
Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. |
