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MAP2K7 cDNA ORF clone, Homo sapiens(human)

Summary

Gene Symbol MAP2K7
Entrez Gene ID 5609
Full Name mitogen-activated protein kinase kinase 7
Synonyms JNKK2,MAPKK7,MEK,MEK 7,MKK7,PRKMK7,SAPKK-4,SAPKK4
General protein information
Preferred Names

mitogen-activated protein kinase kinase 7

Names

dual specificity mitogen-activated protein kinase kinase 7
JNK-activating kinase 2
MAP kinase kinase 7
MAPK/ERK kinase 7
SAPK kinase 4
c-Jun N-terminal kinase kinase 2
stress-activated protein kinase kinase 4
Gene Type protein-coding
Organism Homo sapiens(human)
Genome

19

19p13.2
Summary The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014].
Disorder MIM:

603014


Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_001297556.2 NP_001284485.1 dual specificity mitogen-activated protein kinase kinase 7 isoform 2
NM_145185.4 NP_660186.1 dual specificity mitogen-activated protein kinase kinase 7 isoform 3
NM_145185.3 NP_660186.1 dual specificity mitogen-activated protein kinase kinase 7 isoform 3
NM_001297556.1 NP_001284485.1 dual specificity mitogen-activated protein kinase kinase 7 isoform 2
NM_001297555.1 NP_001284484.1 dual specificity mitogen-activated protein kinase kinase 7 isoform 1
XM_006722800.2 XP_006722863.1 dual specificity mitogen-activated protein kinase kinase 7 isoform X1
NM_001297555.2 NP_001284484.1 dual specificity mitogen-activated protein kinase kinase 7 isoform 1

Pathways from BioSystems


Homologies


Danio rerio (zebrafish) map2k7 NP_001177235.1
Homo sapiens (human) MAP2K7 NP_660186.1
Canis lupus familiaris (dog) MAP2K7 XP_542122.2
Caenorhabditis elegans (roundworm) mek-1 NP_001024771.1
Pan troglodytes (chimpanzee) MAP2K7 XP_003316108.1
Bos taurus (cattle) MAP2K7 XP_002688882.2
Rattus norvegicus (Norway rat) Map2k7 NP_001020596.1
Mus musculus (house mouse) Map2k7 NP_001036022.1
Drosophila melanogaster (fruit fly) hep NP_511142.2
Xenopus tropicalis (tropical clawed frog) map2k7 NP_001027523.1

Gene Ontology

The following MAP2K7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAP2K7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu28930 NM_001297555.2
Latest version!		 Homo sapiens mitogen-activated protein kinase kinase 7 (MAP2K7), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $159.50-$223.30
$319.00
OHu28934 NM_001297556.2
Latest version!		 Homo sapiens mitogen-activated protein kinase kinase 7 (MAP2K7), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu28940 NM_145185.4
Latest version!		 Homo sapiens mitogen-activated protein kinase kinase 7 (MAP2K7), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu51702 XM_006722800.2
Latest version!		 Homo sapiens mitogen-activated protein kinase kinase 7 (MAP2K7), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
View Old Accession Versions >>
OHu28940 NM_145185.3 Homo sapiens mitogen-activated protein kinase kinase 7 (MAP2K7), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu28934 NM_001297556.1 Homo sapiens mitogen-activated protein kinase kinase 7 (MAP2K7), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu28930 NM_001297555.1 Homo sapiens mitogen-activated protein kinase kinase 7 (MAP2K7), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $159.50-$223.30
$319.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu28930
Clone ID Related Accession (Same CDS sequence) NM_001297555.1 , NM_001297555.2
Accession Version NM_001297555.1 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1308bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2018-09-29
Organism Homo sapiens(human)
Product dual specificity mitogen-activated protein kinase kinase 7 isoform 1
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY099294.1, HY063492.1, DQ445915.1, BC038295.2, AK300988.1, AK098807.1 and BF445461.1. On Jul 3, 2014 this sequence version replaced XM_005272489.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK300988.1, DQ445915.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGCGGCGT CCTCCCTGGA ACAGAAGCTG TCCCGCCTGG AAGCAAAGCT GAAGCAGGAG 
AACCGGGAGG CCCGGCGGAG GATCGACCTC AACCTGGATA TCAGCCCCCA GCGGCCCAGG 
CCCATTATTG TGATCACTCT AAGCCCTGCT CCTGCCCCGT CCCAACGAGC AGCCCTGCAG 
CTCCCGCTGG CCAACGATGG GGGCAGCCGC TCGCCATCCT CAGAGAGCTC CCCGCAGCAC 
CCCACGCCCC CCGCCCGGCC CCGCCACATG CTGGGGCTCC CGTCAACCCT GTTCACACCC 
CGCAGCATGG AGAGCATTGA GATTGACCAG AAGCTGCAGG AGATCATGAA GCAGACGGGC 
TACCTGACCA TCGGGGGCCA GCGCTACCAG GCAGAAATCA ACGACCTGGA GAACTTGGGC 
GAGATGGGCA GCGGCACCTG CGGCCAGGTG TGGAAGATGC GCTTCCGGAA GACCGGCCAC 
GTCATTGCCG TTAAGCAAAT GCGGCGCTCC GGGAACAAGG AGGAGAACAA GCGCATCCTC 
ATGGACCTGG ATGTGGTGCT GAAGAGCCAC GACTGCCCCT ACATCGTGCA GTGCTTTGGG 
ACGTTCATCA CCAACACGGA CGTCTTCATC GCCATGGAGC TCATGGGCAC CTGCGCTGAG 
AAGCTCAAGA AGCGGATGCA GGGCCCCATC CCCGAGCGCA TTCTGGGCAA GATGACAGTG 
GCGATTGTGA AGGCGCTGTA CTACCTGAAG GAGAAGCACG GTGTCATCCA CCGCGACGTC 
AAGCCCTCCA ACATCCTGCT GGACGAGCGG GGCCAGATCA AGCTCTGCGA CTTCGGCATC 
AGCGGCCGCC TGGTGGACTC CAAAGCCAAG ACGCGGAGCG CCGGCTGTGC CGCCTACATG 
GCACCCGAGC GCATTGACCC CCCAGACCCC ACCAAGCCGG ACTATGACAT CCGGGCCGAC 
GTATGGAGCC TGGGCATCTC GTTGGTGGAG CTGGCAACAG GACAGTTTCC CTACAAGAAC 
TGCAAGACGG ACTTTGAGGT CCTCACCAAA GTCCTACAGG AAGAGCCCCC GCTTCTGCCC 
GGACACATGG GCTTCTCGGG GGACTTCCAG TCCTTCGTCA AAGACTGCCT TACTAAAGAT 
CACAGGAAGA GACCAAAGTA TAATAAGCTA CTTGAACACA GCTTCATCAA GCGCTACGAG 
ACGCTGGAGG TGGACGTGGC GTCCTGGTTC AAGGATGTCA TGGCGAAGAC TGAGTCACCG 
CGGACTAGCG GCGTCCTGAG CCAGCCCCAC CTGCCCTTCT TCAGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001284484.1
CDS166..1473
Translation

Target ORF information:

RefSeq Version NM_001297555.1
Organism Homo sapiens(human)
Definition Homo sapiens mitogen-activated protein kinase kinase 7 (MAP2K7), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001297555.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGCGGCGT CCTCCCTGGA ACAGAAGCTG TCCCGCCTGG AAGCAAAGCT GAAGCAGGAG 
AACCGGGAGG CCCGGCGGAG GATCGACCTC AACCTGGATA TCAGCCCCCA GCGGCCCAGG 
CCCATTATTG TGATCACTCT AAGCCCTGCT CCTGCCCCGT CCCAACGAGC AGCCCTGCAG 
CTCCCGCTGG CCAACGATGG GGGCAGCCGC TCGCCATCCT CAGAGAGCTC CCCGCAGCAC 
CCCACGCCCC CCGCCCGGCC CCGCCACATG CTGGGGCTCC CGTCAACCCT GTTCACACCC 
CGCAGCATGG AGAGCATTGA GATTGACCAG AAGCTGCAGG AGATCATGAA GCAGACGGGC 
TACCTGACCA TCGGGGGCCA GCGCTACCAG GCAGAAATCA ACGACCTGGA GAACTTGGGC 
GAGATGGGCA GCGGCACCTG CGGCCAGGTG TGGAAGATGC GCTTCCGGAA GACCGGCCAC 
GTCATTGCCG TTAAGCAAAT GCGGCGCTCC GGGAACAAGG AGGAGAACAA GCGCATCCTC 
ATGGACCTGG ATGTGGTGCT GAAGAGCCAC GACTGCCCCT ACATCGTGCA GTGCTTTGGG 
ACGTTCATCA CCAACACGGA CGTCTTCATC GCCATGGAGC TCATGGGCAC CTGCGCTGAG 
AAGCTCAAGA AGCGGATGCA GGGCCCCATC CCCGAGCGCA TTCTGGGCAA GATGACAGTG 
GCGATTGTGA AGGCGCTGTA CTACCTGAAG GAGAAGCACG GTGTCATCCA CCGCGACGTC 
AAGCCCTCCA ACATCCTGCT GGACGAGCGG GGCCAGATCA AGCTCTGCGA CTTCGGCATC 
AGCGGCCGCC TGGTGGACTC CAAAGCCAAG ACGCGGAGCG CCGGCTGTGC CGCCTACATG 
GCACCCGAGC GCATTGACCC CCCAGACCCC ACCAAGCCGG ACTATGACAT CCGGGCCGAC 
GTATGGAGCC TGGGCATCTC GTTGGTGGAG CTGGCAACAG GACAGTTTCC CTACAAGAAC 
TGCAAGACGG ACTTTGAGGT CCTCACCAAA GTCCTACAGG AAGAGCCCCC GCTTCTGCCC 
GGACACATGG GCTTCTCGGG GGACTTCCAG TCCTTCGTCA AAGACTGCCT TACTAAAGAT 
CACAGGAAGA GACCAAAGTA TAATAAGCTA CTTGAACACA GCTTCATCAA GCGCTACGAG 
ACGCTGGAGG TGGACGTGGC GTCCTGGTTC AAGGATGTCA TGGCGAAGAC TGAGTCACCG 
CGGACTAGCG GCGTCCTGAG CCAGCCCCAC CTGCCCTTCT TCAGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu28930
Clone ID Related Accession (Same CDS sequence) NM_001297555.1 , NM_001297555.2
Accession Version NM_001297555.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1308bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2020-01-03
Organism Homo sapiens(human)
Product dual specificity mitogen-activated protein kinase kinase 7 isoform 1
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY063492.1, DQ445915.1, BC038295.2, AK300988.1, AK098807.1 and BF445461.1. On Jun 2, 2019 this sequence version replaced NM_001297555.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.572781.1, SRR3476690.1136777.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGCGGCGT CCTCCCTGGA ACAGAAGCTG TCCCGCCTGG AAGCAAAGCT GAAGCAGGAG 
AACCGGGAGG CCCGGCGGAG GATCGACCTC AACCTGGATA TCAGCCCCCA GCGGCCCAGG 
CCCATTATTG TGATCACTCT AAGCCCTGCT CCTGCCCCGT CCCAACGAGC AGCCCTGCAG 
CTCCCGCTGG CCAACGATGG GGGCAGCCGC TCGCCATCCT CAGAGAGCTC CCCGCAGCAC 
CCCACGCCCC CCGCCCGGCC CCGCCACATG CTGGGGCTCC CGTCAACCCT GTTCACACCC 
CGCAGCATGG AGAGCATTGA GATTGACCAG AAGCTGCAGG AGATCATGAA GCAGACGGGC 
TACCTGACCA TCGGGGGCCA GCGCTACCAG GCAGAAATCA ACGACCTGGA GAACTTGGGC 
GAGATGGGCA GCGGCACCTG CGGCCAGGTG TGGAAGATGC GCTTCCGGAA GACCGGCCAC 
GTCATTGCCG TTAAGCAAAT GCGGCGCTCC GGGAACAAGG AGGAGAACAA GCGCATCCTC 
ATGGACCTGG ATGTGGTGCT GAAGAGCCAC GACTGCCCCT ACATCGTGCA GTGCTTTGGG 
ACGTTCATCA CCAACACGGA CGTCTTCATC GCCATGGAGC TCATGGGCAC CTGCGCTGAG 
AAGCTCAAGA AGCGGATGCA GGGCCCCATC CCCGAGCGCA TTCTGGGCAA GATGACAGTG 
GCGATTGTGA AGGCGCTGTA CTACCTGAAG GAGAAGCACG GTGTCATCCA CCGCGACGTC 
AAGCCCTCCA ACATCCTGCT GGACGAGCGG GGCCAGATCA AGCTCTGCGA CTTCGGCATC 
AGCGGCCGCC TGGTGGACTC CAAAGCCAAG ACGCGGAGCG CCGGCTGTGC CGCCTACATG 
GCACCCGAGC GCATTGACCC CCCAGACCCC ACCAAGCCGG ACTATGACAT CCGGGCCGAC 
GTATGGAGCC TGGGCATCTC GTTGGTGGAG CTGGCAACAG GACAGTTTCC CTACAAGAAC 
TGCAAGACGG ACTTTGAGGT CCTCACCAAA GTCCTACAGG AAGAGCCCCC GCTTCTGCCC 
GGACACATGG GCTTCTCGGG GGACTTCCAG TCCTTCGTCA AAGACTGCCT TACTAAAGAT 
CACAGGAAGA GACCAAAGTA TAATAAGCTA CTTGAACACA GCTTCATCAA GCGCTACGAG 
ACGCTGGAGG TGGACGTGGC GTCCTGGTTC AAGGATGTCA TGGCGAAGAC TGAGTCACCG 
CGGACTAGCG GCGTCCTGAG CCAGCCCCAC CTGCCCTTCT TCAGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001284484.1
CDS69..1376
Translation

Target ORF information:

RefSeq Version NM_001297555.2
Organism Homo sapiens(human)
Definition Homo sapiens mitogen-activated protein kinase kinase 7 (MAP2K7), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001297555.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGCGGCGT CCTCCCTGGA ACAGAAGCTG TCCCGCCTGG AAGCAAAGCT GAAGCAGGAG 
AACCGGGAGG CCCGGCGGAG GATCGACCTC AACCTGGATA TCAGCCCCCA GCGGCCCAGG 
CCCATTATTG TGATCACTCT AAGCCCTGCT CCTGCCCCGT CCCAACGAGC AGCCCTGCAG 
CTCCCGCTGG CCAACGATGG GGGCAGCCGC TCGCCATCCT CAGAGAGCTC CCCGCAGCAC 
CCCACGCCCC CCGCCCGGCC CCGCCACATG CTGGGGCTCC CGTCAACCCT GTTCACACCC 
CGCAGCATGG AGAGCATTGA GATTGACCAG AAGCTGCAGG AGATCATGAA GCAGACGGGC 
TACCTGACCA TCGGGGGCCA GCGCTACCAG GCAGAAATCA ACGACCTGGA GAACTTGGGC 
GAGATGGGCA GCGGCACCTG CGGCCAGGTG TGGAAGATGC GCTTCCGGAA GACCGGCCAC 
GTCATTGCCG TTAAGCAAAT GCGGCGCTCC GGGAACAAGG AGGAGAACAA GCGCATCCTC 
ATGGACCTGG ATGTGGTGCT GAAGAGCCAC GACTGCCCCT ACATCGTGCA GTGCTTTGGG 
ACGTTCATCA CCAACACGGA CGTCTTCATC GCCATGGAGC TCATGGGCAC CTGCGCTGAG 
AAGCTCAAGA AGCGGATGCA GGGCCCCATC CCCGAGCGCA TTCTGGGCAA GATGACAGTG 
GCGATTGTGA AGGCGCTGTA CTACCTGAAG GAGAAGCACG GTGTCATCCA CCGCGACGTC 
AAGCCCTCCA ACATCCTGCT GGACGAGCGG GGCCAGATCA AGCTCTGCGA CTTCGGCATC 
AGCGGCCGCC TGGTGGACTC CAAAGCCAAG ACGCGGAGCG CCGGCTGTGC CGCCTACATG 
GCACCCGAGC GCATTGACCC CCCAGACCCC ACCAAGCCGG ACTATGACAT CCGGGCCGAC 
GTATGGAGCC TGGGCATCTC GTTGGTGGAG CTGGCAACAG GACAGTTTCC CTACAAGAAC 
TGCAAGACGG ACTTTGAGGT CCTCACCAAA GTCCTACAGG AAGAGCCCCC GCTTCTGCCC 
GGACACATGG GCTTCTCGGG GGACTTCCAG TCCTTCGTCA AAGACTGCCT TACTAAAGAT 
CACAGGAAGA GACCAAAGTA TAATAAGCTA CTTGAACACA GCTTCATCAA GCGCTACGAG 
ACGCTGGAGG TGGACGTGGC GTCCTGGTTC AAGGATGTCA TGGCGAAGAC TGAGTCACCG 
CGGACTAGCG GCGTCCTGAG CCAGCCCCAC CTGCCCTTCT TCAGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu28934
Clone ID Related Accession (Same CDS sequence) NM_001297556.2 , NM_001297556.1
Accession Version NM_001297556.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1281bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2020-01-03
Organism Homo sapiens(human)
Product dual specificity mitogen-activated protein kinase kinase 7 isoform 2
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY063492.1, BC038295.2, AK300988.1, AK098807.1 and BF445461.1. On Jun 2, 2019 this sequence version replaced NM_001297556.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. It encodes isoform 2, which is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC038295.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGCGGCGT CCTCCCTGGA ACAGAAGCTG TCCCGCCTGG AAGCAAAGCT GAAGCAGGAG 
AACCGGGAGG CCCGGCGGAG GATCGACCTC AACCTGGATA TCAGCCCCCA GCGGCCCAGG 
CCCACCCTGC AGCTCCCGCT GGCCAACGAT GGGGGCAGCC GCTCGCCATC CTCAGAGAGC 
TCCCCGCAGC ACCCCACGCC CCCCGCCCGG CCCCGCCACA TGCTGGGGCT CCCGTCAACC 
CTGTTCACAC CCCGCAGCAT GGAGAGCATT GAGATTGACC AGAAGCTGCA GGAGATCATG 
AAGCAGACGG GCTACCTGAC CATCGGGGGC CAGCGCTACC AGGCAGAAAT CAACGACCTG 
GAGAACTTGG GCGAGATGGG CAGCGGCACC TGCGGCCAGG TGTGGAAGAT GCGCTTCCGG 
AAGACCGGCC ACGTCATTGC CGTTAAGCAA ATGCGGCGCT CCGGGAACAA GGAGGAGAAC 
AAGCGCATCC TCATGGACCT GGATGTGGTG CTGAAGAGCC ACGACTGCCC CTACATCGTG 
CAGTGCTTTG GGACGTTCAT CACCAACACG GACGTCTTCA TCGCCATGGA GCTCATGGGC 
ACCTGCGCTG AGAAGCTCAA GAAGCGGATG CAGGGCCCCA TCCCCGAGCG CATTCTGGGC 
AAGATGACAG TGGCGATTGT GAAGGCGCTG TACTACCTGA AGGAGAAGCA CGGTGTCATC 
CACCGCGACG TCAAGCCCTC CAACATCCTG CTGGACGAGC GGGGCCAGAT CAAGCTCTGC 
GACTTCGGCA TCAGCGGCCG CCTGGTGGAC TCCAAAGCCA AGACGCGGAG CGCCGGCTGT 
GCCGCCTACA TGGCACCCGA GCGCATTGAC CCCCCAGACC CCACCAAGCC GGACTATGAC 
ATCCGGGCCG ACGTATGGAG CCTGGGCATC TCGTTGCCCT GCCCGTCTCC CTCCCAGGTG 
GAGCTGGCAA CAGGACAGTT TCCCTACAAG AACTGCAAGA CGGACTTTGA GGTCCTCACC 
AAAGTCCTAC AGGAAGAGCC CCCGCTTCTG CCCGGACACA TGGGCTTCTC GGGGGACTTC 
CAGTCCTTCG TCAAAGACTG CCTTACTAAA GATCACAGGA AGAGACCAAA GTATAATAAG 
CTACTTGAAC ACAGCTTCAT CAAGCGCTAC GAGACGCTGG AGGTGGACGT GGCGTCCTGG 
TTCAAGGATG TCATGGCGAA GACTGAGTCA CCGCGGACTA GCGGCGTCCT GAGCCAGCCC 
CACCTGCCCT TCTTCAGGTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001284485.1
CDS69..1349
Translation

Target ORF information:

RefSeq Version NM_001297556.2
Organism Homo sapiens(human)
Definition Homo sapiens mitogen-activated protein kinase kinase 7 (MAP2K7), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001297556.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGCGGCGT CCTCCCTGGA ACAGAAGCTG TCCCGCCTGG AAGCAAAGCT GAAGCAGGAG 
AACCGGGAGG CCCGGCGGAG GATCGACCTC AACCTGGATA TCAGCCCCCA GCGGCCCAGG 
CCCACCCTGC AGCTCCCGCT GGCCAACGAT GGGGGCAGCC GCTCGCCATC CTCAGAGAGC 
TCCCCGCAGC ACCCCACGCC CCCCGCCCGG CCCCGCCACA TGCTGGGGCT CCCGTCAACC 
CTGTTCACAC CCCGCAGCAT GGAGAGCATT GAGATTGACC AGAAGCTGCA GGAGATCATG 
AAGCAGACGG GCTACCTGAC CATCGGGGGC CAGCGCTACC AGGCAGAAAT CAACGACCTG 
GAGAACTTGG GCGAGATGGG CAGCGGCACC TGCGGCCAGG TGTGGAAGAT GCGCTTCCGG 
AAGACCGGCC ACGTCATTGC CGTTAAGCAA ATGCGGCGCT CCGGGAACAA GGAGGAGAAC 
AAGCGCATCC TCATGGACCT GGATGTGGTG CTGAAGAGCC ACGACTGCCC CTACATCGTG 
CAGTGCTTTG GGACGTTCAT CACCAACACG GACGTCTTCA TCGCCATGGA GCTCATGGGC 
ACCTGCGCTG AGAAGCTCAA GAAGCGGATG CAGGGCCCCA TCCCCGAGCG CATTCTGGGC 
AAGATGACAG TGGCGATTGT GAAGGCGCTG TACTACCTGA AGGAGAAGCA CGGTGTCATC 
CACCGCGACG TCAAGCCCTC CAACATCCTG CTGGACGAGC GGGGCCAGAT CAAGCTCTGC 
GACTTCGGCA TCAGCGGCCG CCTGGTGGAC TCCAAAGCCA AGACGCGGAG CGCCGGCTGT 
GCCGCCTACA TGGCACCCGA GCGCATTGAC CCCCCAGACC CCACCAAGCC GGACTATGAC 
ATCCGGGCCG ACGTATGGAG CCTGGGCATC TCGTTGCCCT GCCCGTCTCC CTCCCAGGTG 
GAGCTGGCAA CAGGACAGTT TCCCTACAAG AACTGCAAGA CGGACTTTGA GGTCCTCACC 
AAAGTCCTAC AGGAAGAGCC CCCGCTTCTG CCCGGACACA TGGGCTTCTC GGGGGACTTC 
CAGTCCTTCG TCAAAGACTG CCTTACTAAA GATCACAGGA AGAGACCAAA GTATAATAAG 
CTACTTGAAC ACAGCTTCAT CAAGCGCTAC GAGACGCTGG AGGTGGACGT GGCGTCCTGG 
TTCAAGGATG TCATGGCGAA GACTGAGTCA CCGCGGACTA GCGGCGTCCT GAGCCAGCCC 
CACCTGCCCT TCTTCAGGTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu28934
Clone ID Related Accession (Same CDS sequence) NM_001297556.2 , NM_001297556.1
Accession Version NM_001297556.1 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1281bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-02-23
Organism Homo sapiens(human)
Product dual specificity mitogen-activated protein kinase kinase 7 isoform 2
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY099294.1, HY063492.1, BC038295.2, AK300988.1, AK098807.1 and BF445461.1. On Jul 3, 2014 this sequence version replaced XM_005272490.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. It encodes isoform 2, which is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC038295.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGCGGCGT CCTCCCTGGA ACAGAAGCTG TCCCGCCTGG AAGCAAAGCT GAAGCAGGAG 
AACCGGGAGG CCCGGCGGAG GATCGACCTC AACCTGGATA TCAGCCCCCA GCGGCCCAGG 
CCCACCCTGC AGCTCCCGCT GGCCAACGAT GGGGGCAGCC GCTCGCCATC CTCAGAGAGC 
TCCCCGCAGC ACCCCACGCC CCCCGCCCGG CCCCGCCACA TGCTGGGGCT CCCGTCAACC 
CTGTTCACAC CCCGCAGCAT GGAGAGCATT GAGATTGACC AGAAGCTGCA GGAGATCATG 
AAGCAGACGG GCTACCTGAC CATCGGGGGC CAGCGCTACC AGGCAGAAAT CAACGACCTG 
GAGAACTTGG GCGAGATGGG CAGCGGCACC TGCGGCCAGG TGTGGAAGAT GCGCTTCCGG 
AAGACCGGCC ACGTCATTGC CGTTAAGCAA ATGCGGCGCT CCGGGAACAA GGAGGAGAAC 
AAGCGCATCC TCATGGACCT GGATGTGGTG CTGAAGAGCC ACGACTGCCC CTACATCGTG 
CAGTGCTTTG GGACGTTCAT CACCAACACG GACGTCTTCA TCGCCATGGA GCTCATGGGC 
ACCTGCGCTG AGAAGCTCAA GAAGCGGATG CAGGGCCCCA TCCCCGAGCG CATTCTGGGC 
AAGATGACAG TGGCGATTGT GAAGGCGCTG TACTACCTGA AGGAGAAGCA CGGTGTCATC 
CACCGCGACG TCAAGCCCTC CAACATCCTG CTGGACGAGC GGGGCCAGAT CAAGCTCTGC 
GACTTCGGCA TCAGCGGCCG CCTGGTGGAC TCCAAAGCCA AGACGCGGAG CGCCGGCTGT 
GCCGCCTACA TGGCACCCGA GCGCATTGAC CCCCCAGACC CCACCAAGCC GGACTATGAC 
ATCCGGGCCG ACGTATGGAG CCTGGGCATC TCGTTGCCCT GCCCGTCTCC CTCCCAGGTG 
GAGCTGGCAA CAGGACAGTT TCCCTACAAG AACTGCAAGA CGGACTTTGA GGTCCTCACC 
AAAGTCCTAC AGGAAGAGCC CCCGCTTCTG CCCGGACACA TGGGCTTCTC GGGGGACTTC 
CAGTCCTTCG TCAAAGACTG CCTTACTAAA GATCACAGGA AGAGACCAAA GTATAATAAG 
CTACTTGAAC ACAGCTTCAT CAAGCGCTAC GAGACGCTGG AGGTGGACGT GGCGTCCTGG 
TTCAAGGATG TCATGGCGAA GACTGAGTCA CCGCGGACTA GCGGCGTCCT GAGCCAGCCC 
CACCTGCCCT TCTTCAGGTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001284485.1
CDS166..1446
Translation

Target ORF information:

RefSeq Version NM_001297556.1
Organism Homo sapiens(human)
Definition Homo sapiens mitogen-activated protein kinase kinase 7 (MAP2K7), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001297556.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGCGGCGT CCTCCCTGGA ACAGAAGCTG TCCCGCCTGG AAGCAAAGCT GAAGCAGGAG 
AACCGGGAGG CCCGGCGGAG GATCGACCTC AACCTGGATA TCAGCCCCCA GCGGCCCAGG 
CCCACCCTGC AGCTCCCGCT GGCCAACGAT GGGGGCAGCC GCTCGCCATC CTCAGAGAGC 
TCCCCGCAGC ACCCCACGCC CCCCGCCCGG CCCCGCCACA TGCTGGGGCT CCCGTCAACC 
CTGTTCACAC CCCGCAGCAT GGAGAGCATT GAGATTGACC AGAAGCTGCA GGAGATCATG 
AAGCAGACGG GCTACCTGAC CATCGGGGGC CAGCGCTACC AGGCAGAAAT CAACGACCTG 
GAGAACTTGG GCGAGATGGG CAGCGGCACC TGCGGCCAGG TGTGGAAGAT GCGCTTCCGG 
AAGACCGGCC ACGTCATTGC CGTTAAGCAA ATGCGGCGCT CCGGGAACAA GGAGGAGAAC 
AAGCGCATCC TCATGGACCT GGATGTGGTG CTGAAGAGCC ACGACTGCCC CTACATCGTG 
CAGTGCTTTG GGACGTTCAT CACCAACACG GACGTCTTCA TCGCCATGGA GCTCATGGGC 
ACCTGCGCTG AGAAGCTCAA GAAGCGGATG CAGGGCCCCA TCCCCGAGCG CATTCTGGGC 
AAGATGACAG TGGCGATTGT GAAGGCGCTG TACTACCTGA AGGAGAAGCA CGGTGTCATC 
CACCGCGACG TCAAGCCCTC CAACATCCTG CTGGACGAGC GGGGCCAGAT CAAGCTCTGC 
GACTTCGGCA TCAGCGGCCG CCTGGTGGAC TCCAAAGCCA AGACGCGGAG CGCCGGCTGT 
GCCGCCTACA TGGCACCCGA GCGCATTGAC CCCCCAGACC CCACCAAGCC GGACTATGAC 
ATCCGGGCCG ACGTATGGAG CCTGGGCATC TCGTTGCCCT GCCCGTCTCC CTCCCAGGTG 
GAGCTGGCAA CAGGACAGTT TCCCTACAAG AACTGCAAGA CGGACTTTGA GGTCCTCACC 
AAAGTCCTAC AGGAAGAGCC CCCGCTTCTG CCCGGACACA TGGGCTTCTC GGGGGACTTC 
CAGTCCTTCG TCAAAGACTG CCTTACTAAA GATCACAGGA AGAGACCAAA GTATAATAAG 
CTACTTGAAC ACAGCTTCAT CAAGCGCTAC GAGACGCTGG AGGTGGACGT GGCGTCCTGG 
TTCAAGGATG TCATGGCGAA GACTGAGTCA CCGCGGACTA GCGGCGTCCT GAGCCAGCCC 
CACCTGCCCT TCTTCAGGTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu28940
Clone ID Related Accession (Same CDS sequence) NM_145185.4 , NM_145185.3
Accession Version NM_145185.4 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1260bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2020-01-03
Organism Homo sapiens(human)
Product dual specificity mitogen-activated protein kinase kinase 7 isoform 3
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY063492.1, AF022805.1, BC038295.2, AK098807.1 and BF445461.1. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2019 this sequence version replaced NM_145185.3. Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. It encodes isoform 3, which lacks an internal segment and is shorter, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.71668.1, SRR7346977.1103218.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGCGGCGT CCTCCCTGGA ACAGAAGCTG TCCCGCCTGG AAGCAAAGCT GAAGCAGGAG 
AACCGGGAGG CCCGGCGGAG GATCGACCTC AACCTGGATA TCAGCCCCCA GCGGCCCAGG 
CCCACCCTGC AGCTCCCGCT GGCCAACGAT GGGGGCAGCC GCTCGCCATC CTCAGAGAGC 
TCCCCGCAGC ACCCCACGCC CCCCGCCCGG CCCCGCCACA TGCTGGGGCT CCCGTCAACC 
CTGTTCACAC CCCGCAGCAT GGAGAGCATT GAGATTGACC AGAAGCTGCA GGAGATCATG 
AAGCAGACGG GCTACCTGAC CATCGGGGGC CAGCGCTACC AGGCAGAAAT CAACGACCTG 
GAGAACTTGG GCGAGATGGG CAGCGGCACC TGCGGCCAGG TGTGGAAGAT GCGCTTCCGG 
AAGACCGGCC ACGTCATTGC CGTTAAGCAA ATGCGGCGCT CCGGGAACAA GGAGGAGAAC 
AAGCGCATCC TCATGGACCT GGATGTGGTG CTGAAGAGCC ACGACTGCCC CTACATCGTG 
CAGTGCTTTG GGACGTTCAT CACCAACACG GACGTCTTCA TCGCCATGGA GCTCATGGGC 
ACCTGCGCTG AGAAGCTCAA GAAGCGGATG CAGGGCCCCA TCCCCGAGCG CATTCTGGGC 
AAGATGACAG TGGCGATTGT GAAGGCGCTG TACTACCTGA AGGAGAAGCA CGGTGTCATC 
CACCGCGACG TCAAGCCCTC CAACATCCTG CTGGACGAGC GGGGCCAGAT CAAGCTCTGC 
GACTTCGGCA TCAGCGGCCG CCTGGTGGAC TCCAAAGCCA AGACGCGGAG CGCCGGCTGT 
GCCGCCTACA TGGCACCCGA GCGCATTGAC CCCCCAGACC CCACCAAGCC GGACTATGAC 
ATCCGGGCCG ACGTATGGAG CCTGGGCATC TCGTTGGTGG AGCTGGCAAC AGGACAGTTT 
CCCTACAAGA ACTGCAAGAC GGACTTTGAG GTCCTCACCA AAGTCCTACA GGAAGAGCCC 
CCGCTTCTGC CCGGACACAT GGGCTTCTCG GGGGACTTCC AGTCCTTCGT CAAAGACTGC 
CTTACTAAAG ATCACAGGAA GAGACCAAAG TATAATAAGC TACTTGAACA CAGCTTCATC 
AAGCGCTACG AGACGCTGGA GGTGGACGTG GCGTCCTGGT TCAAGGATGT CATGGCGAAG 
ACTGAGTCAC CGCGGACTAG CGGCGTCCTG AGCCAGCCCC ACCTGCCCTT CTTCAGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_660186.1
CDS69..1328
Translation

Target ORF information:

RefSeq Version NM_145185.4
Organism Homo sapiens(human)
Definition Homo sapiens mitogen-activated protein kinase kinase 7 (MAP2K7), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_145185.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGCGGCGT CCTCCCTGGA ACAGAAGCTG TCCCGCCTGG AAGCAAAGCT GAAGCAGGAG 
AACCGGGAGG CCCGGCGGAG GATCGACCTC AACCTGGATA TCAGCCCCCA GCGGCCCAGG 
CCCACCCTGC AGCTCCCGCT GGCCAACGAT GGGGGCAGCC GCTCGCCATC CTCAGAGAGC 
TCCCCGCAGC ACCCCACGCC CCCCGCCCGG CCCCGCCACA TGCTGGGGCT CCCGTCAACC 
CTGTTCACAC CCCGCAGCAT GGAGAGCATT GAGATTGACC AGAAGCTGCA GGAGATCATG 
AAGCAGACGG GCTACCTGAC CATCGGGGGC CAGCGCTACC AGGCAGAAAT CAACGACCTG 
GAGAACTTGG GCGAGATGGG CAGCGGCACC TGCGGCCAGG TGTGGAAGAT GCGCTTCCGG 
AAGACCGGCC ACGTCATTGC CGTTAAGCAA ATGCGGCGCT CCGGGAACAA GGAGGAGAAC 
AAGCGCATCC TCATGGACCT GGATGTGGTG CTGAAGAGCC ACGACTGCCC CTACATCGTG 
CAGTGCTTTG GGACGTTCAT CACCAACACG GACGTCTTCA TCGCCATGGA GCTCATGGGC 
ACCTGCGCTG AGAAGCTCAA GAAGCGGATG CAGGGCCCCA TCCCCGAGCG CATTCTGGGC 
AAGATGACAG TGGCGATTGT GAAGGCGCTG TACTACCTGA AGGAGAAGCA CGGTGTCATC 
CACCGCGACG TCAAGCCCTC CAACATCCTG CTGGACGAGC GGGGCCAGAT CAAGCTCTGC 
GACTTCGGCA TCAGCGGCCG CCTGGTGGAC TCCAAAGCCA AGACGCGGAG CGCCGGCTGT 
GCCGCCTACA TGGCACCCGA GCGCATTGAC CCCCCAGACC CCACCAAGCC GGACTATGAC 
ATCCGGGCCG ACGTATGGAG CCTGGGCATC TCGTTGGTGG AGCTGGCAAC AGGACAGTTT 
CCCTACAAGA ACTGCAAGAC GGACTTTGAG GTCCTCACCA AAGTCCTACA GGAAGAGCCC 
CCGCTTCTGC CCGGACACAT GGGCTTCTCG GGGGACTTCC AGTCCTTCGT CAAAGACTGC 
CTTACTAAAG ATCACAGGAA GAGACCAAAG TATAATAAGC TACTTGAACA CAGCTTCATC 
AAGCGCTACG AGACGCTGGA GGTGGACGTG GCGTCCTGGT TCAAGGATGT CATGGCGAAG 
ACTGAGTCAC CGCGGACTAG CGGCGTCCTG AGCCAGCCCC ACCTGCCCTT CTTCAGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu28940
Clone ID Related Accession (Same CDS sequence) NM_145185.4 , NM_145185.3
Accession Version NM_145185.3 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1260bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-02-23
Organism Homo sapiens(human)
Product dual specificity mitogen-activated protein kinase kinase 7 isoform 3
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY099294.1, HY063492.1, AF022805.1, BC038295.2, AK098807.1 and BF445461.1. This sequence is a reference standard in the RefSeqGene project. On Jul 3, 2014 this sequence version replaced NM_145185.2. Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. It encodes isoform 3, which lacks an internal segment and is shorter, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF013588.1, AF022805.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGCGGCGT CCTCCCTGGA ACAGAAGCTG TCCCGCCTGG AAGCAAAGCT GAAGCAGGAG 
AACCGGGAGG CCCGGCGGAG GATCGACCTC AACCTGGATA TCAGCCCCCA GCGGCCCAGG 
CCCACCCTGC AGCTCCCGCT GGCCAACGAT GGGGGCAGCC GCTCGCCATC CTCAGAGAGC 
TCCCCGCAGC ACCCCACGCC CCCCGCCCGG CCCCGCCACA TGCTGGGGCT CCCGTCAACC 
CTGTTCACAC CCCGCAGCAT GGAGAGCATT GAGATTGACC AGAAGCTGCA GGAGATCATG 
AAGCAGACGG GCTACCTGAC CATCGGGGGC CAGCGCTACC AGGCAGAAAT CAACGACCTG 
GAGAACTTGG GCGAGATGGG CAGCGGCACC TGCGGCCAGG TGTGGAAGAT GCGCTTCCGG 
AAGACCGGCC ACGTCATTGC CGTTAAGCAA ATGCGGCGCT CCGGGAACAA GGAGGAGAAC 
AAGCGCATCC TCATGGACCT GGATGTGGTG CTGAAGAGCC ACGACTGCCC CTACATCGTG 
CAGTGCTTTG GGACGTTCAT CACCAACACG GACGTCTTCA TCGCCATGGA GCTCATGGGC 
ACCTGCGCTG AGAAGCTCAA GAAGCGGATG CAGGGCCCCA TCCCCGAGCG CATTCTGGGC 
AAGATGACAG TGGCGATTGT GAAGGCGCTG TACTACCTGA AGGAGAAGCA CGGTGTCATC 
CACCGCGACG TCAAGCCCTC CAACATCCTG CTGGACGAGC GGGGCCAGAT CAAGCTCTGC 
GACTTCGGCA TCAGCGGCCG CCTGGTGGAC TCCAAAGCCA AGACGCGGAG CGCCGGCTGT 
GCCGCCTACA TGGCACCCGA GCGCATTGAC CCCCCAGACC CCACCAAGCC GGACTATGAC 
ATCCGGGCCG ACGTATGGAG CCTGGGCATC TCGTTGGTGG AGCTGGCAAC AGGACAGTTT 
CCCTACAAGA ACTGCAAGAC GGACTTTGAG GTCCTCACCA AAGTCCTACA GGAAGAGCCC 
CCGCTTCTGC CCGGACACAT GGGCTTCTCG GGGGACTTCC AGTCCTTCGT CAAAGACTGC 
CTTACTAAAG ATCACAGGAA GAGACCAAAG TATAATAAGC TACTTGAACA CAGCTTCATC 
AAGCGCTACG AGACGCTGGA GGTGGACGTG GCGTCCTGGT TCAAGGATGT CATGGCGAAG 
ACTGAGTCAC CGCGGACTAG CGGCGTCCTG AGCCAGCCCC ACCTGCCCTT CTTCAGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_660186.1
CDS166..1425
Translation

Target ORF information:

RefSeq Version NM_145185.3
Organism Homo sapiens(human)
Definition Homo sapiens mitogen-activated protein kinase kinase 7 (MAP2K7), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_145185.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGCGGCGT CCTCCCTGGA ACAGAAGCTG TCCCGCCTGG AAGCAAAGCT GAAGCAGGAG 
AACCGGGAGG CCCGGCGGAG GATCGACCTC AACCTGGATA TCAGCCCCCA GCGGCCCAGG 
CCCACCCTGC AGCTCCCGCT GGCCAACGAT GGGGGCAGCC GCTCGCCATC CTCAGAGAGC 
TCCCCGCAGC ACCCCACGCC CCCCGCCCGG CCCCGCCACA TGCTGGGGCT CCCGTCAACC 
CTGTTCACAC CCCGCAGCAT GGAGAGCATT GAGATTGACC AGAAGCTGCA GGAGATCATG 
AAGCAGACGG GCTACCTGAC CATCGGGGGC CAGCGCTACC AGGCAGAAAT CAACGACCTG 
GAGAACTTGG GCGAGATGGG CAGCGGCACC TGCGGCCAGG TGTGGAAGAT GCGCTTCCGG 
AAGACCGGCC ACGTCATTGC CGTTAAGCAA ATGCGGCGCT CCGGGAACAA GGAGGAGAAC 
AAGCGCATCC TCATGGACCT GGATGTGGTG CTGAAGAGCC ACGACTGCCC CTACATCGTG 
CAGTGCTTTG GGACGTTCAT CACCAACACG GACGTCTTCA TCGCCATGGA GCTCATGGGC 
ACCTGCGCTG AGAAGCTCAA GAAGCGGATG CAGGGCCCCA TCCCCGAGCG CATTCTGGGC 
AAGATGACAG TGGCGATTGT GAAGGCGCTG TACTACCTGA AGGAGAAGCA CGGTGTCATC 
CACCGCGACG TCAAGCCCTC CAACATCCTG CTGGACGAGC GGGGCCAGAT CAAGCTCTGC 
GACTTCGGCA TCAGCGGCCG CCTGGTGGAC TCCAAAGCCA AGACGCGGAG CGCCGGCTGT 
GCCGCCTACA TGGCACCCGA GCGCATTGAC CCCCCAGACC CCACCAAGCC GGACTATGAC 
ATCCGGGCCG ACGTATGGAG CCTGGGCATC TCGTTGGTGG AGCTGGCAAC AGGACAGTTT 
CCCTACAAGA ACTGCAAGAC GGACTTTGAG GTCCTCACCA AAGTCCTACA GGAAGAGCCC 
CCGCTTCTGC CCGGACACAT GGGCTTCTCG GGGGACTTCC AGTCCTTCGT CAAAGACTGC 
CTTACTAAAG ATCACAGGAA GAGACCAAAG TATAATAAGC TACTTGAACA CAGCTTCATC 
AAGCGCTACG AGACGCTGGA GGTGGACGTG GCGTCCTGGT TCAAGGATGT CATGGCGAAG 
ACTGAGTCAC CGCGGACTAG CGGCGTCCTG AGCCAGCCCC ACCTGCCCTT CTTCAGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu51702
Clone ID Related Accession (Same CDS sequence) XM_006722800.2
Accession Version XM_006722800.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1329bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-05
Organism Homo sapiens(human)
Product dual specificity mitogen-activated protein kinase kinase 7 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_006722800.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGGCGGCGT CCTCCCTGGA ACAGAAGCTG TCCCGCCTGG AAGCAAAGCT GAAGCAGGAG 
AACCGGGAGG CCCGGCGGAG GATCGACCTC AACCTGGATA TCAGCCCCCA GCGGCCCAGG 
CCCATTATTG TGATCACTCT AAGCCCTGCT CCTGCCCCGT CCCAACGAGC AGCCCTGCAG 
CTCCCGCTGG CCAACGATGG GGGCAGCCGC TCGCCATCCT CAGAGAGCTC CCCGCAGCAC 
CCCACGCCCC CCGCCCGGCC CCGCCACATG CTGGGGCTCC CGTCAACCCT GTTCACACCC 
CGCAGCATGG AGAGCATTGA GATTGACCAG AAGCTGCAGG AGATCATGAA GCAGACGGGC 
TACCTGACCA TCGGGGGCCA GCGCTACCAG GCAGAAATCA ACGACCTGGA GAACTTGGGC 
GAGATGGGCA GCGGCACCTG CGGCCAGGTG TGGAAGATGC GCTTCCGGAA GACCGGCCAC 
GTCATTGCCG TTAAGCAAAT GCGGCGCTCC GGGAACAAGG AGGAGAACAA GCGCATCCTC 
ATGGACCTGG ATGTGGTGCT GAAGAGCCAC GACTGCCCCT ACATCGTGCA GTGCTTTGGG 
ACGTTCATCA CCAACACGGA CGTCTTCATC GCCATGGAGC TCATGGGCAC CTGCGCTGAG 
AAGCTCAAGA AGCGGATGCA GGGCCCCATC CCCGAGCGCA TTCTGGGCAA GATGACAGTG 
GCGATTGTGA AGGCGCTGTA CTACCTGAAG GAGAAGCACG GTGTCATCCA CCGCGACGTC 
AAGCCCTCCA ACATCCTGCT GGACGAGCGG GGCCAGATCA AGCTCTGCGA CTTCGGCATC 
AGCGGCCGCC TGGTGGACTC CAAAGCCAAG ACGCGGAGCG CCGGCTGTGC CGCCTACATG 
GCACCCGAGC GCATTGACCC CCCAGACCCC ACCAAGCCGG ACTATGACAT CCGGGCCGAC 
GTATGGAGCC TGGGCATCTC GTTGCCCTGC CCGTCTCCCT CCCAGGTGGA GCTGGCAACA 
GGACAGTTTC CCTACAAGAA CTGCAAGACG GACTTTGAGG TCCTCACCAA AGTCCTACAG 
GAAGAGCCCC CGCTTCTGCC CGGACACATG GGCTTCTCGG GGGACTTCCA GTCCTTCGTC 
AAAGACTGCC TTACTAAAGA TCACAGGAAG AGACCAAAGT ATAATAAGCT ACTTGAACAC 
AGCTTCATCA AGCGCTACGA GACGCTGGAG GTGGACGTGG CGTCCTGGTT CAAGGATGTC 
ATGGCGAAGA CTGAGTCACC GCGGACTAGC GGCGTCCTGA GCCAGCCCCA CCTGCCCTTC 
TTCAGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006722863.1
CDS161..1489
Translation

Target ORF information:

RefSeq Version XM_006722800.2
Organism Homo sapiens(human)
Definition Homo sapiens mitogen-activated protein kinase kinase 7 (MAP2K7), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006722800.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGGCGGCGT CCTCCCTGGA ACAGAAGCTG TCCCGCCTGG AAGCAAAGCT GAAGCAGGAG 
AACCGGGAGG CCCGGCGGAG GATCGACCTC AACCTGGATA TCAGCCCCCA GCGGCCCAGG 
CCCATTATTG TGATCACTCT AAGCCCTGCT CCTGCCCCGT CCCAACGAGC AGCCCTGCAG 
CTCCCGCTGG CCAACGATGG GGGCAGCCGC TCGCCATCCT CAGAGAGCTC CCCGCAGCAC 
CCCACGCCCC CCGCCCGGCC CCGCCACATG CTGGGGCTCC CGTCAACCCT GTTCACACCC 
CGCAGCATGG AGAGCATTGA GATTGACCAG AAGCTGCAGG AGATCATGAA GCAGACGGGC 
TACCTGACCA TCGGGGGCCA GCGCTACCAG GCAGAAATCA ACGACCTGGA GAACTTGGGC 
GAGATGGGCA GCGGCACCTG CGGCCAGGTG TGGAAGATGC GCTTCCGGAA GACCGGCCAC 
GTCATTGCCG TTAAGCAAAT GCGGCGCTCC GGGAACAAGG AGGAGAACAA GCGCATCCTC 
ATGGACCTGG ATGTGGTGCT GAAGAGCCAC GACTGCCCCT ACATCGTGCA GTGCTTTGGG 
ACGTTCATCA CCAACACGGA CGTCTTCATC GCCATGGAGC TCATGGGCAC CTGCGCTGAG 
AAGCTCAAGA AGCGGATGCA GGGCCCCATC CCCGAGCGCA TTCTGGGCAA GATGACAGTG 
GCGATTGTGA AGGCGCTGTA CTACCTGAAG GAGAAGCACG GTGTCATCCA CCGCGACGTC 
AAGCCCTCCA ACATCCTGCT GGACGAGCGG GGCCAGATCA AGCTCTGCGA CTTCGGCATC 
AGCGGCCGCC TGGTGGACTC CAAAGCCAAG ACGCGGAGCG CCGGCTGTGC CGCCTACATG 
GCACCCGAGC GCATTGACCC CCCAGACCCC ACCAAGCCGG ACTATGACAT CCGGGCCGAC 
GTATGGAGCC TGGGCATCTC GTTGCCCTGC CCGTCTCCCT CCCAGGTGGA GCTGGCAACA 
GGACAGTTTC CCTACAAGAA CTGCAAGACG GACTTTGAGG TCCTCACCAA AGTCCTACAG 
GAAGAGCCCC CGCTTCTGCC CGGACACATG GGCTTCTCGG GGGACTTCCA GTCCTTCGTC 
AAAGACTGCC TTACTAAAGA TCACAGGAAG AGACCAAAGT ATAATAAGCT ACTTGAACAC 
AGCTTCATCA AGCGCTACGA GACGCTGGAG GTGGACGTGG CGTCCTGGTT CAAGGATGTC 
ATGGCGAAGA CTGAGTCACC GCGGACTAGC GGCGTCCTGA GCCAGCCCCA CCTGCCCTTC 
TTCAGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed