MS4A5 cDNA ORF clone, Homo sapiens(human)
Gene Symbol | MS4A5 |
Entrez Gene ID | 64232 |
Full Name | membrane spanning 4-domains A5 |
Synonyms | CD20-L2,CD20L2,TETM4 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. Though this member is not expressed in hematopoietic cells specifically, it may be involved in signal transduction like many of its related family members. The gene encoding this protein is localized to 11q12, among a cluster of family members. [provided by RefSeq, Jul 2008]. |
Disorder MIM: |
mRNA and Protein(s)
mRNA | Protein | Name |
---|---|---|
NM_023945.3 | NP_076434.2 | membrane-spanning 4-domains subfamily A member 5 |
NM_023945.2 | NP_076434.2 | membrane-spanning 4-domains subfamily A member 5 |

MS4A5 | XP_001086601.1 | |
Mus musculus (house mouse) | Ms4a5 | NP_899013.1 |
Pan troglodytes (chimpanzee) | MS4A5 | XP_508460.1 |
Canis lupus familiaris (dog) | MS4A5 | XP_855393.1 |
Bos taurus (cattle) | MS4A5 | NP_001071614.1 |
Rattus norvegicus (Norway rat) | Ms4a5 | XP_003749114.1 |
Homo sapiens (human) | MS4A5 | NP_076434.2 |

Related articles in PubMed
New genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M
Genes and immunity11(3)232-8(2010 Apr)
Structural organization of the human MS4A gene cluster on Chromosome 11q12.
Liang Y, Buckley TR, Tu L, Langdon SD, Tedder TF
Immunogenetics53(5)357-68(2001 Jul)
Identification of a CD20-, FcepsilonRIbeta-, and HTm4-related gene family: sixteen new MS4A family members expressed in human and mouse.
Liang Y, Tedder TF
Genomics72(2)119-27(2001 Mar)
Identification of a new multigene four-transmembrane family (MS4A) related to CD20, HTm4 and beta subunit of the high-affinity IgE receptor.
Ishibashi K, Suzuki M, Sasaki S, Imai M
Gene264(1)87-93(2001 Feb)
Isolation, tissue distribution, and chromosomal localization of a novel testis-specific human four-transmembrane gene related to CD20 and FcepsilonRI-beta.
Hulett MD, Pagler E, Hornby JR, Hogarth PM, Eyre HJ, Baker E, Crawford J, Sutherland GR, Ohms SJ, Parish CR
Biochemical and biophysical research communications280(1)374-9(2001 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Observational study of gene-disease association. (HuGE Navigator)
Title: New genetic associations detected in a host response study to hepatitis B vaccine.
The following MS4A5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MS4A5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OHu29432![]() |
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Clone ID Related Accession (Same CDS sequence) | NM_023945.3 , NM_023945.2 | |
Accession Version | NM_023945.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 603bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-27 | |
Organism | Homo sapiens(human) | |
Product | membrane-spanning 4-domains subfamily A member 5 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP003127.2 and BC029884.1. On Nov 23, 2018 this sequence version replaced NM_023945.2. ##Evidence-Data-START## Transcript exon combination :: SRR5189667.131933.1, BI829760.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000300190.7/ ENSP00000300190.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGGATTCAA GCACCGCACA CAGTCCGGTG TTTCTGGTAT TTCCTCCAGA AATCACTGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_076434.2 |
CDS | 104..706 |
Translation |

Target ORF information:
Target ORF information:
|
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ORF Insert Sequence:
1 | ATGGATTCAA GCACCGCACA CAGTCCGGTG TTTCTGGTAT TTCCTCCAGA AATCACTGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu29432![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_023945.3 , NM_023945.2 | |
Accession Version | NM_023945.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 603bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-09-30 | |
Organism | Homo sapiens(human) | |
Product | membrane-spanning 4-domains subfamily A member 5 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC029884.1. On Sep 18, 2002 this sequence version replaced NM_023945.1. ##Evidence-Data-START## Transcript exon combination :: BC029884.1, BQ429208.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGATTCAA GCACCGCACA CAGTCCGGTG TTTCTGGTAT TTCCTCCAGA AATCACTGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_076434.2 |
CDS | 87..689 |
Translation |

Target ORF information:
Target ORF information:
|
![]() |

ORF Insert Sequence:
1 | ATGGATTCAA GCACCGCACA CAGTCCGGTG TTTCTGGTAT TTCCTCCAGA AATCACTGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
![]() |
New genetic associations detected in a host response study to hepatitis B vaccine. |
![]() |
Structural organization of the human MS4A gene cluster on Chromosome 11q12. |
![]() |
Identification of a CD20-, FcepsilonRIbeta-, and HTm4-related gene family: sixteen new MS4A family members expressed in human and mouse. |
![]() |
Identification of a new multigene four-transmembrane family (MS4A) related to CD20, HTm4 and beta subunit of the high-affinity IgE receptor. |
![]() |
Isolation, tissue distribution, and chromosomal localization of a novel testis-specific human four-transmembrane gene related to CD20 and FcepsilonRI-beta. |