Tmem100 cDNA ORF clone, Mus musculus(house mouse)
Gene Symbol | Tmem100 |
Entrez Gene ID | 67888 |
Full Name | transmembrane protein 100 |
Synonyms | 1810057C19Rik,AV011897 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA and Protein(s)
mRNA | Protein | Name |
---|---|---|
XM_006534030.2 | XP_006534093.1 | transmembrane protein 100 isoform X1 |
NM_026433.2 | NP_080709.1 | transmembrane protein 100 |
XM_006534031.1 | XP_006534094.1 | transmembrane protein 100 isoform X1 |
XM_006534030.3 | XP_006534093.1 | transmembrane protein 100 isoform X1 |
XM_006534030.4 | XP_006534093.1 | transmembrane protein 100 isoform X1 |

Pan troglodytes (chimpanzee) | TMEM100 | XP_003315670.1 |
Canis lupus familiaris (dog) | TMEM100 | XP_005624756.1 |
Homo sapiens (human) | TMEM100 | NP_001093110.1 |
Mus musculus (house mouse) | Tmem100 | NP_080709.1 |
Gallus gallus (chicken) | TMEM100 | XP_415651.1 |
Danio rerio (zebrafish) | LOC100334742 | XP_002667042.1 |
TMEM100 | XP_001103766.1 | |
Bos taurus (cattle) | TMEM100 | NP_001039987.1 |
Xenopus tropicalis (tropical clawed frog) | tmem100 | XP_004918619.1 |
Rattus norvegicus (Norway rat) | Tmem100 | NP_001017479.1 |

Related articles in PubMed
BMP7 plays a critical role in TMEM100-inhibited cell proliferation and apoptosis in mouse metanephric mesenchymal cells in vitro.
Ren D, Ju P, Liu J, Ni D, Gu Y, Long Y, Zhou Q, Xie Y
In vitro cellular & developmental biology. Animal54(2)111-119(2018 Feb)
High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)
Essential role for TMEM100 in vascular integrity but limited contributions to the pathogenesis of hereditary haemorrhagic telangiectasia.
Moon EH, Kim YS, Seo J, Lee S, Lee YJ, Oh SP
Cardiovascular research105(3)353-60(2015 Mar)
Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain.
Weng HJ, Patel KN, Jeske NA, Bierbower SM, Zou W, Tiwari V, Zheng Q, Tang Z, Mo GC, Wang Y, Geng Y, Zhang J, Guan Y, Akopian AN, Dong X
Neuron85(4)833-46(2015 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
TMEM100 has essential functions for the maintenance of vascular integrity as well as the formation of blood vessels.
Title: Essential role for TMEM100 in vascular integrity but limited contributions to the pathogenesis of hereditary haemorrhagic telangiectasia.
This study demonistrated that Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain in mice.
Title: Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain.
The Tmem100 deficiency causes EndMT defect during AVC cushion formation possibly via disturbance of multiple calcium-related signaling events.
Title: Impairment of endothelial-mesenchymal transformation during atrioventricular cushion formation in Tmem100 null embryos.
This study demonistrated that TMEM100 is a novel, membrane-associated marker for enteric nerves and is as effective as PGP9.5 for identifying neuronal structures in the gastrointestinal tract.
Title: Distribution of TMEM100 in the mouse and human gastrointestinal tract--a novel marker of enteric nerves.
TMEM100 may play indispensable roles downstream of BMP9/BMP10-ALK1 signaling during endothelial differentiation and vascular morphogenesis.
Title: Tmem100, an ALK1 receptor signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesis.
The following Tmem100 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tmem100 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu02279 | |
Clone ID Related Accession (Same CDS sequence) | XM_006534030.2 , NM_026433.2 , XM_006534031.1 , XM_006534030.3 , XM_006534030.4 | |
Accession Version | NM_026433.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 405bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-03 | |
Organism | Mus musculus(house mouse) | |
Product | transmembrane protein 100 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK007878.1. On Apr 6, 2007 this sequence version replaced NM_026433.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK007878.1, BC034841.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGACCGAAG AATCCACAAA AGAGAACCTG GGAGCTCCAA AATCTCCCAC ACCTGTGACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_080709.1 |
CDS | 608..1012 |
Translation |

Target ORF information:
Target ORF information:
|
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ORF Insert Sequence:
1 | ATGACCGAAG AATCCACAAA AGAGAACCTG GGAGCTCCAA AATCTCCCAC ACCTGTGACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu02279 | |
Clone ID Related Accession (Same CDS sequence) | XM_006534030.2 , NM_026433.2 , XM_006534031.1 , XM_006534030.3 , XM_006534030.4 | |
Accession Version | XM_006534030.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 405bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-02-08 | |
Organism | Mus musculus(House mouse) | |
Product | transmembrane protein 100 isoform X1 | |
Comment |
1 | ATGACCGAAG AATCCACAAA AGAGAACCTG GGAGCTCCAA AATCTCCCAC ACCTGTGACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006534093.1 |
Translation |

Target ORF information:
Target ORF information:
|
![]() |

ORF Insert Sequence:
1 | ATGACCGAAG AATCCACAAA AGAGAACCTG GGAGCTCCAA AATCTCCCAC ACCTGTGACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu02279 | |
Clone ID Related Accession (Same CDS sequence) | XM_006534030.2 , NM_026433.2 , XM_006534031.1 , XM_006534030.3 , XM_006534030.4 | |
Accession Version | XM_006534031.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 405bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | transmembrane protein 100 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACCGAAG AATCCACAAA AGAGAACCTG GGAGCTCCAA AATCTCCCAC ACCTGTGACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006534094.1 |
CDS | 314..718 |
Translation |

Target ORF information:
Target ORF information:
|
![]() |

ORF Insert Sequence:
1 | ATGACCGAAG AATCCACAAA AGAGAACCTG GGAGCTCCAA AATCTCCCAC ACCTGTGACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu02279 | |
Clone ID Related Accession (Same CDS sequence) | XM_006534030.2 , NM_026433.2 , XM_006534031.1 , XM_006534030.3 , XM_006534030.4 | |
Accession Version | XM_006534030.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 405bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | transmembrane protein 100 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006534030.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACCGAAG AATCCACAAA AGAGAACCTG GGAGCTCCAA AATCTCCCAC ACCTGTGACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006534093.1 |
CDS | 405..809 |
Translation |

Target ORF information:
Target ORF information:
|
![]() |

ORF Insert Sequence:
1 | ATGACCGAAG AATCCACAAA AGAGAACCTG GGAGCTCCAA AATCTCCCAC ACCTGTGACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu02279 | |
Clone ID Related Accession (Same CDS sequence) | XM_006534030.2 , NM_026433.2 , XM_006534031.1 , XM_006534030.3 , XM_006534030.4 | |
Accession Version | XM_006534030.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 405bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | transmembrane protein 100 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006534030.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACCGAAG AATCCACAAA AGAGAACCTG GGAGCTCCAA AATCTCCCAC ACCTGTGACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006534093.1 |
CDS | 396..800 |
Translation |

Target ORF information:
Target ORF information:
|
![]() |

ORF Insert Sequence:
1 | ATGACCGAAG AATCCACAAA AGAGAACCTG GGAGCTCCAA AATCTCCCAC ACCTGTGACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
![]() |
BMP7 plays a critical role in TMEM100-inhibited cell proliferation and apoptosis in mouse metanephric mesenchymal cells in vitro. |
![]() |
High-throughput discovery of novel developmental phenotypes. |
![]() |
Essential role for TMEM100 in vascular integrity but limited contributions to the pathogenesis of hereditary haemorrhagic telangiectasia. |
![]() |
Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain. |