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Tmem100 cDNA ORF clone, Mus musculus(house mouse)

Summary

Gene Symbol Tmem100
Entrez Gene ID 67888
Full Name transmembrane protein 100
Synonyms 1810057C19Rik,AV011897
General protein information
Preferred Names

transmembrane protein 100

Names

transmembrane protein 100
Gene Type protein-coding
Organism Mus musculus(house mouse)
Genome

11

11|11 C

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_006534030.2 XP_006534093.1 transmembrane protein 100 isoform X1
NM_026433.2 NP_080709.1 transmembrane protein 100
XM_006534031.1 XP_006534094.1 transmembrane protein 100 isoform X1
XM_006534030.3 XP_006534093.1 transmembrane protein 100 isoform X1
XM_006534030.4 XP_006534093.1 transmembrane protein 100 isoform X1

Pathways from BioSystems


Homologies


Pan troglodytes (chimpanzee) TMEM100 XP_003315670.1
Canis lupus familiaris (dog) TMEM100 XP_005624756.1
Homo sapiens (human) TMEM100 NP_001093110.1
Mus musculus (house mouse) Tmem100 NP_080709.1
Gallus gallus (chicken) TMEM100 XP_415651.1
Danio rerio (zebrafish) LOC100334742 XP_002667042.1
TMEM100 XP_001103766.1
Bos taurus (cattle) TMEM100 NP_001039987.1
Xenopus tropicalis (tropical clawed frog) tmem100 XP_004918619.1
Rattus norvegicus (Norway rat) Tmem100 NP_001017479.1

Gene Ontology


Bibliography

Related articles in PubMed

BMP7 plays a critical role in TMEM100-inhibited cell proliferation and apoptosis in mouse metanephric mesenchymal cells in vitro.
Ren D, Ju P, Liu J, Ni D, Gu Y, Long Y, Zhou Q, Xie Y
In vitro cellular & developmental biology. Animal54(2)111-119(2018 Feb)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Essential role for TMEM100 in vascular integrity but limited contributions to the pathogenesis of hereditary haemorrhagic telangiectasia.
Moon EH, Kim YS, Seo J, Lee S, Lee YJ, Oh SP
Cardiovascular research105(3)353-60(2015 Mar)

Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain.
Weng HJ, Patel KN, Jeske NA, Bierbower SM, Zou W, Tiwari V, Zheng Q, Tang Z, Mo GC, Wang Y, Geng Y, Zhang J, Guan Y, Akopian AN, Dong X
Neuron85(4)833-46(2015 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

TMEM100 has essential functions for the maintenance of vascular integrity as well as the formation of blood vessels.
Title: Essential role for TMEM100 in vascular integrity but limited contributions to the pathogenesis of hereditary haemorrhagic telangiectasia.

This study demonistrated that Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain in mice.
Title: Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain.

The Tmem100 deficiency causes EndMT defect during AVC cushion formation possibly via disturbance of multiple calcium-related signaling events.
Title: Impairment of endothelial-mesenchymal transformation during atrioventricular cushion formation in Tmem100 null embryos.

This study demonistrated that TMEM100 is a novel, membrane-associated marker for enteric nerves and is as effective as PGP9.5 for identifying neuronal structures in the gastrointestinal tract.
Title: Distribution of TMEM100 in the mouse and human gastrointestinal tract--a novel marker of enteric nerves.

TMEM100 may play indispensable roles downstream of BMP9/BMP10-ALK1 signaling during endothelial differentiation and vascular morphogenesis.
Title: Tmem100, an ALK1 receptor signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesis.

The following Tmem100 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tmem100 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OMu02279 NM_026433.2
Latest version!		 Mus musculus transmembrane protein 100 (Tmem100), mRNA. pcDNA3.1-C-(k)DYK or customized vector 5-7 $69.30
$99.00
OMu02279 XM_006534031.1
Latest version!		 Mus musculus transmembrane protein 100 (Tmem100), transcript variant X2, mRNA. pcDNA3.1-C-(k)DYK or customized vector 5-7 $69.30
$99.00
OMu02279 XM_006534030.4
Latest version!		 Mus musculus transmembrane protein 100 (Tmem100), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $69.30
$99.00
View Old Accession Versions >>
OMu02279 XM_006534030.2 Mus musculus transmembrane protein 100 (Tmem100), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 5-7 $69.30
$99.00
OMu02279 XM_006534030.3 Mus musculus transmembrane protein 100 (Tmem100), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 5-7 $69.30
$99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OMu02279
Clone ID Related Accession (Same CDS sequence) XM_006534030.2 , NM_026433.2 , XM_006534031.1 , XM_006534030.3 , XM_006534030.4
Accession Version NM_026433.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 405bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-03
Organism Mus musculus(house mouse)
Product transmembrane protein 100
Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK007878.1. On Apr 6, 2007 this sequence version replaced NM_026433.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK007878.1, BC034841.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
ATGACCGAAG AATCCACAAA AGAGAACCTG GGAGCTCCAA AATCTCCCAC ACCTGTGACA 
ATGGAGAAAA ACCCCAAGAG GGAAGTTGTG GTCACCACGG GACCCTTGGT CAGCGAGGTT 
CAGCTGATGG CCGCCACCGG GGGTGCCGAA CTCTCCTGCT ACCGCTGCAT CATCCCCTTT 
GCCGTGGTGG TCTTCATCAC TGGGATTGTG GTCACCGCTG TGGCTTACAG CTTCAATTCC 
CATGGTTCCA TCATCTCCAT CTTCGGCCTG GTCCTTCTGT CCTCCGGACT GTTTTTACTA 
GCCTCCAGTG CCTTGTGCTG GAAGGTGAGA CAAAGGAACA AGAAAGTCAA GAGACGCGAG 
AGTCAGACCG CTCTTGTGGT AAATCAGAGG TGCTTGTTTG CTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_080709.1
CDS608..1012
Translation

Target ORF information:

RefSeq Version NM_026433.2
Organism Mus musculus(house mouse)
Definition Mus musculus transmembrane protein 100 (Tmem100), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_026433.2

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGACCGAAG AATCCACAAA AGAGAACCTG GGAGCTCCAA AATCTCCCAC ACCTGTGACA 
ATGGAGAAAA ACCCCAAGAG GGAAGTTGTG GTCACCACGG GACCCTTGGT CAGCGAGGTT 
CAGCTGATGG CCGCCACCGG GGGTGCCGAA CTCTCCTGCT ACCGCTGCAT CATCCCCTTT 
GCCGTGGTGG TCTTCATCAC TGGGATTGTG GTCACCGCTG TGGCTTACAG CTTCAATTCC 
CATGGTTCCA TCATCTCCAT CTTCGGCCTG GTCCTTCTGT CCTCCGGACT GTTTTTACTA 
GCCTCCAGTG CCTTGTGCTG GAAGGTGAGA CAAAGGAACA AGAAAGTCAA GAGACGCGAG 
AGTCAGACCG CTCTTGTGGT AAATCAGAGG TGCTTGTTTG CTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu02279
Clone ID Related Accession (Same CDS sequence) XM_006534030.2 , NM_026433.2 , XM_006534031.1 , XM_006534030.3 , XM_006534030.4
Accession Version XM_006534030.2 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 405bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2015-02-08
Organism Mus musculus(House mouse)
Product transmembrane protein 100 isoform X1
Comment 

1
61
121
181
241
301
361
ATGACCGAAG AATCCACAAA AGAGAACCTG GGAGCTCCAA AATCTCCCAC ACCTGTGACA 
ATGGAGAAAA ACCCCAAGAG GGAAGTTGTG GTCACCACGG GACCCTTGGT CAGCGAGGTT 
CAGCTGATGG CCGCCACCGG GGGTGCCGAA CTCTCCTGCT ACCGCTGCAT CATCCCCTTT 
GCCGTGGTGG TCTTCATCAC TGGGATTGTG GTCACCGCTG TGGCTTACAG CTTCAATTCC 
CATGGTTCCA TCATCTCCAT CTTCGGCCTG GTCCTTCTGT CCTCCGGACT GTTTTTACTA 
GCCTCCAGTG CCTTGTGCTG GAAGGTGAGA CAAAGGAACA AGAAAGTCAA GAGACGCGAG 
AGTCAGACCG CTCTTGTGGT AAATCAGAGG TGCTTGTTTG CTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006534093.1
Translation

Target ORF information:

RefSeq Version XM_006534030.2
Organism Mus musculus(House mouse)
Definition Mus musculus transmembrane protein 100 (Tmem100), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006534030.2

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGACCGAAG AATCCACAAA AGAGAACCTG GGAGCTCCAA AATCTCCCAC ACCTGTGACA 
ATGGAGAAAA ACCCCAAGAG GGAAGTTGTG GTCACCACGG GACCCTTGGT CAGCGAGGTT 
CAGCTGATGG CCGCCACCGG GGGTGCCGAA CTCTCCTGCT ACCGCTGCAT CATCCCCTTT 
GCCGTGGTGG TCTTCATCAC TGGGATTGTG GTCACCGCTG TGGCTTACAG CTTCAATTCC 
CATGGTTCCA TCATCTCCAT CTTCGGCCTG GTCCTTCTGT CCTCCGGACT GTTTTTACTA 
GCCTCCAGTG CCTTGTGCTG GAAGGTGAGA CAAAGGAACA AGAAAGTCAA GAGACGCGAG 
AGTCAGACCG CTCTTGTGGT AAATCAGAGG TGCTTGTTTG CTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu02279
Clone ID Related Accession (Same CDS sequence) XM_006534030.2 , NM_026433.2 , XM_006534031.1 , XM_006534030.3 , XM_006534030.4
Accession Version XM_006534031.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 405bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-07
Organism Mus musculus(house mouse)
Product transmembrane protein 100 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
ATGACCGAAG AATCCACAAA AGAGAACCTG GGAGCTCCAA AATCTCCCAC ACCTGTGACA 
ATGGAGAAAA ACCCCAAGAG GGAAGTTGTG GTCACCACGG GACCCTTGGT CAGCGAGGTT 
CAGCTGATGG CCGCCACCGG GGGTGCCGAA CTCTCCTGCT ACCGCTGCAT CATCCCCTTT 
GCCGTGGTGG TCTTCATCAC TGGGATTGTG GTCACCGCTG TGGCTTACAG CTTCAATTCC 
CATGGTTCCA TCATCTCCAT CTTCGGCCTG GTCCTTCTGT CCTCCGGACT GTTTTTACTA 
GCCTCCAGTG CCTTGTGCTG GAAGGTGAGA CAAAGGAACA AGAAAGTCAA GAGACGCGAG 
AGTCAGACCG CTCTTGTGGT AAATCAGAGG TGCTTGTTTG CTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006534094.1
CDS314..718
Translation

Target ORF information:

RefSeq Version XM_006534031.1
Organism Mus musculus(house mouse)
Definition Mus musculus transmembrane protein 100 (Tmem100), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006534031.1

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGACCGAAG AATCCACAAA AGAGAACCTG GGAGCTCCAA AATCTCCCAC ACCTGTGACA 
ATGGAGAAAA ACCCCAAGAG GGAAGTTGTG GTCACCACGG GACCCTTGGT CAGCGAGGTT 
CAGCTGATGG CCGCCACCGG GGGTGCCGAA CTCTCCTGCT ACCGCTGCAT CATCCCCTTT 
GCCGTGGTGG TCTTCATCAC TGGGATTGTG GTCACCGCTG TGGCTTACAG CTTCAATTCC 
CATGGTTCCA TCATCTCCAT CTTCGGCCTG GTCCTTCTGT CCTCCGGACT GTTTTTACTA 
GCCTCCAGTG CCTTGTGCTG GAAGGTGAGA CAAAGGAACA AGAAAGTCAA GAGACGCGAG 
AGTCAGACCG CTCTTGTGGT AAATCAGAGG TGCTTGTTTG CTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu02279
Clone ID Related Accession (Same CDS sequence) XM_006534030.2 , NM_026433.2 , XM_006534031.1 , XM_006534030.3 , XM_006534030.4
Accession Version XM_006534030.3 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 405bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-21
Organism Mus musculus(house mouse)
Product transmembrane protein 100 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006534030.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
ATGACCGAAG AATCCACAAA AGAGAACCTG GGAGCTCCAA AATCTCCCAC ACCTGTGACA 
ATGGAGAAAA ACCCCAAGAG GGAAGTTGTG GTCACCACGG GACCCTTGGT CAGCGAGGTT 
CAGCTGATGG CCGCCACCGG GGGTGCCGAA CTCTCCTGCT ACCGCTGCAT CATCCCCTTT 
GCCGTGGTGG TCTTCATCAC TGGGATTGTG GTCACCGCTG TGGCTTACAG CTTCAATTCC 
CATGGTTCCA TCATCTCCAT CTTCGGCCTG GTCCTTCTGT CCTCCGGACT GTTTTTACTA 
GCCTCCAGTG CCTTGTGCTG GAAGGTGAGA CAAAGGAACA AGAAAGTCAA GAGACGCGAG 
AGTCAGACCG CTCTTGTGGT AAATCAGAGG TGCTTGTTTG CTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006534093.1
CDS405..809
Translation

Target ORF information:

RefSeq Version XM_006534030.3
Organism Mus musculus(house mouse)
Definition Mus musculus transmembrane protein 100 (Tmem100), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006534030.3

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGACCGAAG AATCCACAAA AGAGAACCTG GGAGCTCCAA AATCTCCCAC ACCTGTGACA 
ATGGAGAAAA ACCCCAAGAG GGAAGTTGTG GTCACCACGG GACCCTTGGT CAGCGAGGTT 
CAGCTGATGG CCGCCACCGG GGGTGCCGAA CTCTCCTGCT ACCGCTGCAT CATCCCCTTT 
GCCGTGGTGG TCTTCATCAC TGGGATTGTG GTCACCGCTG TGGCTTACAG CTTCAATTCC 
CATGGTTCCA TCATCTCCAT CTTCGGCCTG GTCCTTCTGT CCTCCGGACT GTTTTTACTA 
GCCTCCAGTG CCTTGTGCTG GAAGGTGAGA CAAAGGAACA AGAAAGTCAA GAGACGCGAG 
AGTCAGACCG CTCTTGTGGT AAATCAGAGG TGCTTGTTTG CTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu02279
Clone ID Related Accession (Same CDS sequence) XM_006534030.2 , NM_026433.2 , XM_006534031.1 , XM_006534030.3 , XM_006534030.4
Accession Version XM_006534030.4 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 405bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-07
Organism Mus musculus(house mouse)
Product transmembrane protein 100 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006534030.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
ATGACCGAAG AATCCACAAA AGAGAACCTG GGAGCTCCAA AATCTCCCAC ACCTGTGACA 
ATGGAGAAAA ACCCCAAGAG GGAAGTTGTG GTCACCACGG GACCCTTGGT CAGCGAGGTT 
CAGCTGATGG CCGCCACCGG GGGTGCCGAA CTCTCCTGCT ACCGCTGCAT CATCCCCTTT 
GCCGTGGTGG TCTTCATCAC TGGGATTGTG GTCACCGCTG TGGCTTACAG CTTCAATTCC 
CATGGTTCCA TCATCTCCAT CTTCGGCCTG GTCCTTCTGT CCTCCGGACT GTTTTTACTA 
GCCTCCAGTG CCTTGTGCTG GAAGGTGAGA CAAAGGAACA AGAAAGTCAA GAGACGCGAG 
AGTCAGACCG CTCTTGTGGT AAATCAGAGG TGCTTGTTTG CTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006534093.1
CDS396..800
Translation

Target ORF information:

RefSeq Version XM_006534030.4
Organism Mus musculus(house mouse)
Definition Mus musculus transmembrane protein 100 (Tmem100), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006534030.4

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGACCGAAG AATCCACAAA AGAGAACCTG GGAGCTCCAA AATCTCCCAC ACCTGTGACA 
ATGGAGAAAA ACCCCAAGAG GGAAGTTGTG GTCACCACGG GACCCTTGGT CAGCGAGGTT 
CAGCTGATGG CCGCCACCGG GGGTGCCGAA CTCTCCTGCT ACCGCTGCAT CATCCCCTTT 
GCCGTGGTGG TCTTCATCAC TGGGATTGTG GTCACCGCTG TGGCTTACAG CTTCAATTCC 
CATGGTTCCA TCATCTCCAT CTTCGGCCTG GTCCTTCTGT CCTCCGGACT GTTTTTACTA 
GCCTCCAGTG CCTTGTGCTG GAAGGTGAGA CAAAGGAACA AGAAAGTCAA GAGACGCGAG 
AGTCAGACCG CTCTTGTGGT AAATCAGAGG TGCTTGTTTG CTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

BMP7 plays a critical role in TMEM100-inhibited cell proliferation and apoptosis in mouse metanephric mesenchymal cells in vitro.
In vitro cellular & developmental biology. Animal54(2)111-119(2018 Feb)
Ren D,Ju P,Liu J,Ni D,Gu Y,Long Y,Zhou Q,Xie Y


book

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA


book

Essential role for TMEM100 in vascular integrity but limited contributions to the pathogenesis of hereditary haemorrhagic telangiectasia.
Cardiovascular research105(3)353-60(2015 Mar)
Moon EH,Kim YS,Seo J,Lee S,Lee YJ,Oh SP


book

Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain.
Neuron85(4)833-46(2015 Feb)
Weng HJ,Patel KN,Jeske NA,Bierbower SM,Zou W,Tiwari V,Zheng Q,Tang Z,Mo GC,Wang Y,Geng Y,Zhang J,Guan Y,Akopian AN,Dong X