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Pmvk cDNA ORF clone, Mus musculus(house mouse)

Summary

Gene Symbol Pmvk
Entrez Gene ID 68603
Full Name phosphomevalonate kinase
Synonyms 1110011E12Rik,2900002L22Rik,AV001327,PMK,PMKA,PMKASE
General protein information
Preferred Names

phosphomevalonate kinase

Names

phosphomevalonate kinase
Gene Type protein-coding
Organism Mus musculus(house mouse)
Genome

3

3|3 F1

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_027348.1 NP_081624.1 phosphomevalonate kinase isoform 2
NM_001310640.1 NP_001297569.1 phosphomevalonate kinase isoform 3
XM_030252780.1 XP_030108640.1 phosphomevalonate kinase isoform X1
NM_026784.3 NP_081060.2 phosphomevalonate kinase isoform 1

Pathways from BioSystems


Homologies


Canis lupus familiaris (dog) PMVK XP_855082.1
Anopheles gambiae (African malaria mosquito) AgaP_AGAP000338 XP_310779.4
Homo sapiens (human) PMVK NP_006547.1
Pan troglodytes (chimpanzee) PMVK XP_513842.3
Rattus norvegicus (Norway rat) Pmvk NP_001008353.1
Danio rerio (zebrafish) pmvk NP_001077048.1
Drosophila melanogaster (fruit fly) CG10268 NP_609992.1
Bos taurus (cattle) PMVK NP_001039616.1
PMVK XP_001114509.1
Mus musculus (house mouse) Pmvk NP_081060.2
Gallus gallus (chicken) PMVK XP_004948319.1
Caenorhabditis elegans (roundworm) F32D8.13 NP_001256276.1

Gene Ontology


Bibliography

Related articles in PubMed

A compendium of expression patterns of cholesterol biosynthetic enzymes in the mouse embryo.
?i?ecio?lu M, Budak H, Geffers L, ?ankaya M, ?iftci M, Thaller C, Eichele G, K?frevio?lu ??, ?zdemir H
Journal of lipid research56(8)1551-9(2015 Aug)

Transcription profile in mouse four-cell, morula, and blastocyst: Genes implicated in compaction and blastocoel formation.
Cui XS, Li XY, Shen XH, Bae YJ, Kang JJ, Kim NH
Molecular reproduction and development74(2)133-43(2007 Feb)

Absence of functional peroxisomes does not lead to deficiency of enzymes involved in cholesterol biosynthesis.
Hogenboom S, Romeijn GJ, Houten SM, Baes M, Wanders RJ, Waterham HR
Journal of lipid research43(1)90-8(2002 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Pmvk gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pmvk cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OMu70285 NM_001310640.1
Latest version!		 Mus musculus phosphomevalonate kinase (Pmvk), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $69.30
$99.00
OMu03001 NM_026784.3
Latest version!		 Mus musculus phosphomevalonate kinase (Pmvk), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OMu17170 NM_027348.1
Latest version!		 Mus musculus phosphomevalonate kinase (Pmvk), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OMu70285 XM_030252780.1
Latest version!		 Mus musculus phosphomevalonate kinase (Pmvk), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 9-11 $69.30
$99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OMu70285
Clone ID Related Accession (Same CDS sequence) NM_001310640.1 , XM_030252780.1
Accession Version NM_001310640.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 354bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-04-15
Organism Mus musculus(house mouse)
Product phosphomevalonate kinase isoform 3
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC028659.1. On Jul 16, 2015 this sequence version replaced XM_011240212.1. Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start site compared to variant 1. The encoded isoform (3) has a shorter N-terminus than isoform 1. ##Evidence-Data-START## Transcript exon combination :: BC028659.1, BU524619.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849377, SAMN00849384 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
ATGATCTGTT GGGGGGAGCA GAAGCGCCAG GCAGACCCAG GCTTCTTCTG CCGGAAGATT 
GTGGAAGGCG TGTCCCAGCC TATCTGGCTG GTGAGTGACA CACGGAGGAC ATCTGACATC 
CAGTGGTTTC AGGAGGCCTA TGGGGCTGTG ATACAGACAG TCCGAGTAGT GGCCTCGGAG 
CAGAGTCGAC AGCAACGGGG CTGGGTGTTC ACACCAGGGG TGGACGATGC TGAGTCAGAG 
TGTGGTCTGG ACAACTTTGG GAACTTTGAC TGGGTCATTG AGAACCACGG AGATGAGCAG 
TGCCTGGAGG ATCAGCTGGA GCACCTGCTG GGATTTATTC AAGCCAAACT TTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001297569.1
CDS266..619
Translation

Target ORF information:

RefSeq Version NM_001310640.1
Organism Mus musculus(house mouse)
Definition Mus musculus phosphomevalonate kinase (Pmvk), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001310640.1

ORF Insert Sequence:

1
61
121
181
241
301
ATGATCTGTT GGGGGGAGCA GAAGCGCCAG GCAGACCCAG GCTTCTTCTG CCGGAAGATT 
GTGGAAGGCG TGTCCCAGCC TATCTGGCTG GTGAGTGACA CACGGAGGAC ATCTGACATC 
CAGTGGTTTC AGGAGGCCTA TGGGGCTGTG ATACAGACAG TCCGAGTAGT GGCCTCGGAG 
CAGAGTCGAC AGCAACGGGG CTGGGTGTTC ACACCAGGGG TGGACGATGC TGAGTCAGAG 
TGTGGTCTGG ACAACTTTGG GAACTTTGAC TGGGTCATTG AGAACCACGG AGATGAGCAG 
TGCCTGGAGG ATCAGCTGGA GCACCTGCTG GGATTTATTC AAGCCAAACT TTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu03001
Clone ID Related Accession (Same CDS sequence) NM_026784.3
Accession Version NM_026784.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 579bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-04-15
Organism Mus musculus(house mouse)
Product phosphomevalonate kinase isoform 1
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY266316.1, AK003607.1, AK150483.1 and AW492322.1. On Jul 23, 2009 this sequence version replaced NM_026784.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: BY703869.1, AK150483.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
ATGGCCCCGC TCGGAGCCTC CCCGCGTCTG GTGCTGCTGT TTAGCGGGAA GAGAAAATCC 
GGGAAGGACT TCGTGACCGA GAGGCTGAAG AGCAGACTTG GAGGTAACAT CTGTGCTCTC 
CTGCGGCTCT CTGGTCCACT CAAGGAGGAG TATGCTCGGG AGCATGGCTT GGACTTCCAG 
AGACTTCTGG ATGCGAGCAC CTACAAGGAG ACCTATCGGA GGGACATGAT CTGTTGGGGG 
GAGCAGAAGC GCCAGGCAGA CCCAGGCTTC TTCTGCCGGA AGATTGTGGA AGGCGTGTCC 
CAGCCTATCT GGCTGGTGAG TGACACACGG AGGACATCTG ACATCCAGTG GTTTCAGGAG 
GCCTATGGGG CTGTGATACA GACAGTCCGA GTAGTGGCCT CGGAGCAGAG TCGACAGCAA 
CGGGGCTGGG TGTTCACACC AGGGGTGGAC GATGCTGAGT CAGAGTGTGG TCTGGACAAC 
TTTGGGAACT TTGACTGGGT CATTGAGAAC CACGGAGATG AGCAGTGCCT GGAGGATCAG 
CTGGAGCACC TGCTGGGATT TATTCAAGCC AAACTTTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_081060.2
CDS253..831
Translation

Target ORF information:

RefSeq Version NM_026784.3
Organism Mus musculus(house mouse)
Definition Mus musculus phosphomevalonate kinase (Pmvk), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_026784.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGGCCCCGC TCGGAGCCTC CCCGCGTCTG GTGCTGCTGT TTAGCGGGAA GAGAAAATCC 
GGGAAGGACT TCGTGACCGA GAGGCTGAAG AGCAGACTTG GAGGTAACAT CTGTGCTCTC 
CTGCGGCTCT CTGGTCCACT CAAGGAGGAG TATGCTCGGG AGCATGGCTT GGACTTCCAG 
AGACTTCTGG ATGCGAGCAC CTACAAGGAG ACCTATCGGA GGGACATGAT CTGTTGGGGG 
GAGCAGAAGC GCCAGGCAGA CCCAGGCTTC TTCTGCCGGA AGATTGTGGA AGGCGTGTCC 
CAGCCTATCT GGCTGGTGAG TGACACACGG AGGACATCTG ACATCCAGTG GTTTCAGGAG 
GCCTATGGGG CTGTGATACA GACAGTCCGA GTAGTGGCCT CGGAGCAGAG TCGACAGCAA 
CGGGGCTGGG TGTTCACACC AGGGGTGGAC GATGCTGAGT CAGAGTGTGG TCTGGACAAC 
TTTGGGAACT TTGACTGGGT CATTGAGAAC CACGGAGATG AGCAGTGCCT GGAGGATCAG 
CTGGAGCACC TGCTGGGATT TATTCAAGCC AAACTTTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu17170
Clone ID Related Accession (Same CDS sequence) NM_027348.1
Accession Version NM_027348.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 516bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-04-15
Organism Mus musculus(house mouse)
Product phosphomevalonate kinase isoform 2
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK013477.1, AC171273.1, AK150483.1 and AW492322.1. Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK013477.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849384 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
ATGGCAGGAA TTTATGGAAT ATTCTATGCC AGACTTGGAG GTAACATCTG TGCTCTCCTG 
CGGCTCTCTG GTCCACTCAA GGAGGAGTAT GCTCGGGAGC ATGGCTTGGA CTTCCAGAGA 
CTTCTGGATG CGAGCACCTA CAAGGAGACC TATCGGAGGG ACATGATCTG TTGGGGGGAG 
CAGAAGCGCC AGGCAGACCC AGGCTTCTTC TGCCGGAAGA TTGTGGAAGG CGTGTCCCAG 
CCTATCTGGC TGGTGAGTGA CACACGGAGG ACATCTGACA TCCAGTGGTT TCAGGAGGCC 
TATGGGGCTG TGATACAGAC AGTCCGAGTA GTGGCCTCGG AGCAGAGTCG ACAGCAACGG 
GGCTGGGTGT TCACACCAGG GGTGGACGAT GCTGAGTCAG AGTGTGGTCT GGACAACTTT 
GGGAACTTTG ACTGGGTCAT TGAGAACCAC GGAGATGAGC AGTGCCTGGA GGATCAGCTG 
GAGCACCTGC TGGGATTTAT TCAAGCCAAA CTTTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_081624.1
CDS285..800
Translation

Target ORF information:

RefSeq Version NM_027348.1
Organism Mus musculus(house mouse)
Definition Mus musculus phosphomevalonate kinase (Pmvk), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_027348.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGGCAGGAA TTTATGGAAT ATTCTATGCC AGACTTGGAG GTAACATCTG TGCTCTCCTG 
CGGCTCTCTG GTCCACTCAA GGAGGAGTAT GCTCGGGAGC ATGGCTTGGA CTTCCAGAGA 
CTTCTGGATG CGAGCACCTA CAAGGAGACC TATCGGAGGG ACATGATCTG TTGGGGGGAG 
CAGAAGCGCC AGGCAGACCC AGGCTTCTTC TGCCGGAAGA TTGTGGAAGG CGTGTCCCAG 
CCTATCTGGC TGGTGAGTGA CACACGGAGG ACATCTGACA TCCAGTGGTT TCAGGAGGCC 
TATGGGGCTG TGATACAGAC AGTCCGAGTA GTGGCCTCGG AGCAGAGTCG ACAGCAACGG 
GGCTGGGTGT TCACACCAGG GGTGGACGAT GCTGAGTCAG AGTGTGGTCT GGACAACTTT 
GGGAACTTTG ACTGGGTCAT TGAGAACCAC GGAGATGAGC AGTGCCTGGA GGATCAGCTG 
GAGCACCTGC TGGGATTTAT TCAAGCCAAA CTTTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu70285
Clone ID Related Accession (Same CDS sequence) NM_001310640.1 , XM_030252780.1
Accession Version XM_030252780.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 354bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-07
Organism Mus musculus(house mouse)
Product phosphomevalonate kinase isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000069.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
ATGATCTGTT GGGGGGAGCA GAAGCGCCAG GCAGACCCAG GCTTCTTCTG CCGGAAGATT 
GTGGAAGGCG TGTCCCAGCC TATCTGGCTG GTGAGTGACA CACGGAGGAC ATCTGACATC 
CAGTGGTTTC AGGAGGCCTA TGGGGCTGTG ATACAGACAG TCCGAGTAGT GGCCTCGGAG 
CAGAGTCGAC AGCAACGGGG CTGGGTGTTC ACACCAGGGG TGGACGATGC TGAGTCAGAG 
TGTGGTCTGG ACAACTTTGG GAACTTTGAC TGGGTCATTG AGAACCACGG AGATGAGCAG 
TGCCTGGAGG ATCAGCTGGA GCACCTGCTG GGATTTATTC AAGCCAAACT TTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_030108640.1
CDS370..723
Translation

Target ORF information:

RefSeq Version XM_030252780.1
Organism Mus musculus(house mouse)
Definition Mus musculus phosphomevalonate kinase (Pmvk), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_030252780.1

ORF Insert Sequence:

1
61
121
181
241
301
ATGATCTGTT GGGGGGAGCA GAAGCGCCAG GCAGACCCAG GCTTCTTCTG CCGGAAGATT 
GTGGAAGGCG TGTCCCAGCC TATCTGGCTG GTGAGTGACA CACGGAGGAC ATCTGACATC 
CAGTGGTTTC AGGAGGCCTA TGGGGCTGTG ATACAGACAG TCCGAGTAGT GGCCTCGGAG 
CAGAGTCGAC AGCAACGGGG CTGGGTGTTC ACACCAGGGG TGGACGATGC TGAGTCAGAG 
TGTGGTCTGG ACAACTTTGG GAACTTTGAC TGGGTCATTG AGAACCACGG AGATGAGCAG 
TGCCTGGAGG ATCAGCTGGA GCACCTGCTG GGATTTATTC AAGCCAAACT TTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

A compendium of expression patterns of cholesterol biosynthetic enzymes in the mouse embryo.
Journal of lipid research56(8)1551-9(2015 Aug)
?i?ecio?lu M,Budak H,Geffers L,?ankaya M,?iftci M,Thaller C,Eichele G,K?frevio?lu ??,?zdemir H


book

Transcription profile in mouse four-cell, morula, and blastocyst: Genes implicated in compaction and blastocoel formation.
Molecular reproduction and development74(2)133-43(2007 Feb)
Cui XS,Li XY,Shen XH,Bae YJ,Kang JJ,Kim NH


book

Absence of functional peroxisomes does not lead to deficiency of enzymes involved in cholesterol biosynthesis.
Journal of lipid research43(1)90-8(2002 Jan)
Hogenboom S,Romeijn GJ,Houten SM,Baes M,Wanders RJ,Waterham HR