VHL cDNA ORF clone, Homo sapiens(human)

  • Gene

  • Clones

  • gRNAs

The following VHL gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the VHL cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu23297 NM_000551.4
Latest version!
Homo sapiens von Hippel-Lindau tumor suppressor (VHL), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$49.50-$69.30
$99.00
OHu23524 NM_198156.3
Latest version!
Homo sapiens von Hippel-Lindau tumor suppressor (VHL), transcript variant 2, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$49.50-$69.30
$99.00
OHu61302 NM_001354723.2
Latest version!
Homo sapiens von Hippel-Lindau tumor suppressor (VHL), transcript variant 3, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $69.30
$99.00
View Old Accession Versions >>
OHu23297 NM_000551.3 Homo sapiens von Hippel-Lindau tumor suppressor (VHL), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$49.50-$69.30
$99.00
OHu61302 NM_001354723.1 Homo sapiens von Hippel-Lindau tumor suppressor (VHL), transcript variant 3, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $69.30
$99.00
OHu23524 NM_198156.2 Homo sapiens von Hippel-Lindau tumor suppressor (VHL), transcript variant 2, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$49.50-$69.30
$99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

  • Reference Sequences (Refseq)
    CloneID OHu23297
    Clone ID Related Accession (Same CDS sequence) NM_000551.3 , NM_000551.4
    Accession Version NM_000551.3 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 642bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-07-04
    Organism Homo sapiens(human)
    Product von Hippel-Lindau disease tumor suppressor isoform 1
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC034193.5, L15409.1, AK315799.1, BC058831.1 and D58014.1. This sequence is a reference standard in the RefSeqGene project. On Jan 19, 2011 this sequence version replaced NM_000551.2. Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L15409.1, SRR1803611.148663.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGCCCCGGA GGGCGGAGAA CTGGGACGAG GCCGAGGTAG GCGCGGAGGA GGCAGGCGTC 
    GAAGAGTACG GCCCTGAAGA AGACGGCGGG GAGGAGTCGG GCGCCGAGGA GTCCGGCCCG
    GAAGAGTCCG GCCCGGAGGA ACTGGGCGCC GAGGAGGAGA TGGAGGCCGG GCGGCCGCGG
    CCCGTGCTGC GCTCGGTGAA CTCGCGCGAG CCCTCCCAGG TCATCTTCTG CAATCGCAGT
    CCGCGCGTCG TGCTGCCCGT ATGGCTCAAC TTCGACGGCG AGCCGCAGCC CTACCCAACG
    CTGCCGCCTG GCACGGGCCG CCGCATCCAC AGCTACCGAG GTCACCTTTG GCTCTTCAGA
    GATGCAGGGA CACACGATGG GCTTCTGGTT AACCAAACTG AATTATTTGT GCCATCTCTC
    AATGTTGACG GACAGCCTAT TTTTGCCAAT ATCACACTGC CAGTGTATAC TCTGAAAGAG
    CGATGCCTCC AGGTTGTCCG GAGCCTAGTC AAGCCTGAGA ATTACAGGAG ACTGGACATC
    GTCAGGTCGC TCTACGAAGA TCTGGAAGAC CACCCAAATG TGCAGAAAGA CCTGGAGCGG
    CTGACACAGG AGCGCATTGC ACATCAACGG ATGGGAGATT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_000542.1
    CDS214..855
    Translation

    Target ORF information:

    RefSeq Version NM_000551.3
    Organism Homo sapiens(human)
    Definition Homo sapiens von Hippel-Lindau tumor suppressor (VHL), transcript variant 1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_000551.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGCCCCGGA GGGCGGAGAA CTGGGACGAG GCCGAGGTAG GCGCGGAGGA GGCAGGCGTC 
    GAAGAGTACG GCCCTGAAGA AGACGGCGGG GAGGAGTCGG GCGCCGAGGA GTCCGGCCCG
    GAAGAGTCCG GCCCGGAGGA ACTGGGCGCC GAGGAGGAGA TGGAGGCCGG GCGGCCGCGG
    CCCGTGCTGC GCTCGGTGAA CTCGCGCGAG CCCTCCCAGG TCATCTTCTG CAATCGCAGT
    CCGCGCGTCG TGCTGCCCGT ATGGCTCAAC TTCGACGGCG AGCCGCAGCC CTACCCAACG
    CTGCCGCCTG GCACGGGCCG CCGCATCCAC AGCTACCGAG GTCACCTTTG GCTCTTCAGA
    GATGCAGGGA CACACGATGG GCTTCTGGTT AACCAAACTG AATTATTTGT GCCATCTCTC
    AATGTTGACG GACAGCCTAT TTTTGCCAAT ATCACACTGC CAGTGTATAC TCTGAAAGAG
    CGATGCCTCC AGGTTGTCCG GAGCCTAGTC AAGCCTGAGA ATTACAGGAG ACTGGACATC
    GTCAGGTCGC TCTACGAAGA TCTGGAAGAC CACCCAAATG TGCAGAAAGA CCTGGAGCGG
    CTGACACAGG AGCGCATTGC ACATCAACGG ATGGGAGATT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu23297
    Clone ID Related Accession (Same CDS sequence) NM_000551.3 , NM_000551.4
    Accession Version NM_000551.4 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 642bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-19
    Organism Homo sapiens(human)
    Product von Hippel-Lindau disease tumor suppressor isoform 1
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC034193.5. On Nov 30, 2019 this sequence version replaced NM_000551.3. Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7346977.971511.1, L15409.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGCCCCGGA GGGCGGAGAA CTGGGACGAG GCCGAGGTAG GCGCGGAGGA GGCAGGCGTC 
    GAAGAGTACG GCCCTGAAGA AGACGGCGGG GAGGAGTCGG GCGCCGAGGA GTCCGGCCCG
    GAAGAGTCCG GCCCGGAGGA ACTGGGCGCC GAGGAGGAGA TGGAGGCCGG GCGGCCGCGG
    CCCGTGCTGC GCTCGGTGAA CTCGCGCGAG CCCTCCCAGG TCATCTTCTG CAATCGCAGT
    CCGCGCGTCG TGCTGCCCGT ATGGCTCAAC TTCGACGGCG AGCCGCAGCC CTACCCAACG
    CTGCCGCCTG GCACGGGCCG CCGCATCCAC AGCTACCGAG GTCACCTTTG GCTCTTCAGA
    GATGCAGGGA CACACGATGG GCTTCTGGTT AACCAAACTG AATTATTTGT GCCATCTCTC
    AATGTTGACG GACAGCCTAT TTTTGCCAAT ATCACACTGC CAGTGTATAC TCTGAAAGAG
    CGATGCCTCC AGGTTGTCCG GAGCCTAGTC AAGCCTGAGA ATTACAGGAG ACTGGACATC
    GTCAGGTCGC TCTACGAAGA TCTGGAAGAC CACCCAAATG TGCAGAAAGA CCTGGAGCGG
    CTGACACAGG AGCGCATTGC ACATCAACGG ATGGGAGATT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_000542.1
    CDS71..712
    Translation

    Target ORF information:

    RefSeq Version NM_000551.4
    Organism Homo sapiens(human)
    Definition Homo sapiens von Hippel-Lindau tumor suppressor (VHL), transcript variant 1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_000551.4

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGCCCCGGA GGGCGGAGAA CTGGGACGAG GCCGAGGTAG GCGCGGAGGA GGCAGGCGTC 
    GAAGAGTACG GCCCTGAAGA AGACGGCGGG GAGGAGTCGG GCGCCGAGGA GTCCGGCCCG
    GAAGAGTCCG GCCCGGAGGA ACTGGGCGCC GAGGAGGAGA TGGAGGCCGG GCGGCCGCGG
    CCCGTGCTGC GCTCGGTGAA CTCGCGCGAG CCCTCCCAGG TCATCTTCTG CAATCGCAGT
    CCGCGCGTCG TGCTGCCCGT ATGGCTCAAC TTCGACGGCG AGCCGCAGCC CTACCCAACG
    CTGCCGCCTG GCACGGGCCG CCGCATCCAC AGCTACCGAG GTCACCTTTG GCTCTTCAGA
    GATGCAGGGA CACACGATGG GCTTCTGGTT AACCAAACTG AATTATTTGT GCCATCTCTC
    AATGTTGACG GACAGCCTAT TTTTGCCAAT ATCACACTGC CAGTGTATAC TCTGAAAGAG
    CGATGCCTCC AGGTTGTCCG GAGCCTAGTC AAGCCTGAGA ATTACAGGAG ACTGGACATC
    GTCAGGTCGC TCTACGAAGA TCTGGAAGAC CACCCAAATG TGCAGAAAGA CCTGGAGCGG
    CTGACACAGG AGCGCATTGC ACATCAACGG ATGGGAGATT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu23524
    Clone ID Related Accession (Same CDS sequence) NM_198156.3 , NM_198156.2
    Accession Version NM_198156.3 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 519bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-15
    Organism Homo sapiens(human)
    Product von Hippel-Lindau disease tumor suppressor isoform 2
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC034193.5. On Jun 2, 2019 this sequence version replaced NM_198156.2. Transcript Variant: This variant (2) lacks an in-frame coding exon compared to variant 1. The resulting isoform (2) lacks an internal region, as compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.117813.1, SRR1803613.122864.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGCCCCGGA GGGCGGAGAA CTGGGACGAG GCCGAGGTAG GCGCGGAGGA GGCAGGCGTC 
    GAAGAGTACG GCCCTGAAGA AGACGGCGGG GAGGAGTCGG GCGCCGAGGA GTCCGGCCCG
    GAAGAGTCCG GCCCGGAGGA ACTGGGCGCC GAGGAGGAGA TGGAGGCCGG GCGGCCGCGG
    CCCGTGCTGC GCTCGGTGAA CTCGCGCGAG CCCTCCCAGG TCATCTTCTG CAATCGCAGT
    CCGCGCGTCG TGCTGCCCGT ATGGCTCAAC TTCGACGGCG AGCCGCAGCC CTACCCAACG
    CTGCCGCCTG GCACGGGCCG CCGCATCCAC AGCTACCGAG TGTATACTCT GAAAGAGCGA
    TGCCTCCAGG TTGTCCGGAG CCTAGTCAAG CCTGAGAATT ACAGGAGACT GGACATCGTC
    AGGTCGCTCT ACGAAGATCT GGAAGACCAC CCAAATGTGC AGAAAGACCT GGAGCGGCTG
    ACACAGGAGC GCATTGCACA TCAACGGATG GGAGATTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_937799.1
    CDS71..589
    Translation

    Target ORF information:

    RefSeq Version NM_198156.3
    Organism Homo sapiens(human)
    Definition Homo sapiens von Hippel-Lindau tumor suppressor (VHL), transcript variant 2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_198156.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGCCCCGGA GGGCGGAGAA CTGGGACGAG GCCGAGGTAG GCGCGGAGGA GGCAGGCGTC 
    GAAGAGTACG GCCCTGAAGA AGACGGCGGG GAGGAGTCGG GCGCCGAGGA GTCCGGCCCG
    GAAGAGTCCG GCCCGGAGGA ACTGGGCGCC GAGGAGGAGA TGGAGGCCGG GCGGCCGCGG
    CCCGTGCTGC GCTCGGTGAA CTCGCGCGAG CCCTCCCAGG TCATCTTCTG CAATCGCAGT
    CCGCGCGTCG TGCTGCCCGT ATGGCTCAAC TTCGACGGCG AGCCGCAGCC CTACCCAACG
    CTGCCGCCTG GCACGGGCCG CCGCATCCAC AGCTACCGAG TGTATACTCT GAAAGAGCGA
    TGCCTCCAGG TTGTCCGGAG CCTAGTCAAG CCTGAGAATT ACAGGAGACT GGACATCGTC
    AGGTCGCTCT ACGAAGATCT GGAAGACCAC CCAAATGTGC AGAAAGACCT GGAGCGGCTG
    ACACAGGAGC GCATTGCACA TCAACGGATG GGAGATTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu23524
    Clone ID Related Accession (Same CDS sequence) NM_198156.3 , NM_198156.2
    Accession Version NM_198156.2 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 519bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-03-11
    Organism Homo sapiens(human)
    Product von Hippel-Lindau disease tumor suppressor isoform 2
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC034193.5, L15409.1, AK315799.1, BC058831.1 and D58014.1. On Jan 19, 2011 this sequence version replaced NM_198156.1. Transcript Variant: This variant (2) lacks an in-frame coding exon compared to variant 1. The resulting isoform (2) lacks an internal region, as compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.411260.1, BC058831.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGCCCCGGA GGGCGGAGAA CTGGGACGAG GCCGAGGTAG GCGCGGAGGA GGCAGGCGTC 
    GAAGAGTACG GCCCTGAAGA AGACGGCGGG GAGGAGTCGG GCGCCGAGGA GTCCGGCCCG
    GAAGAGTCCG GCCCGGAGGA ACTGGGCGCC GAGGAGGAGA TGGAGGCCGG GCGGCCGCGG
    CCCGTGCTGC GCTCGGTGAA CTCGCGCGAG CCCTCCCAGG TCATCTTCTG CAATCGCAGT
    CCGCGCGTCG TGCTGCCCGT ATGGCTCAAC TTCGACGGCG AGCCGCAGCC CTACCCAACG
    CTGCCGCCTG GCACGGGCCG CCGCATCCAC AGCTACCGAG TGTATACTCT GAAAGAGCGA
    TGCCTCCAGG TTGTCCGGAG CCTAGTCAAG CCTGAGAATT ACAGGAGACT GGACATCGTC
    AGGTCGCTCT ACGAAGATCT GGAAGACCAC CCAAATGTGC AGAAAGACCT GGAGCGGCTG
    ACACAGGAGC GCATTGCACA TCAACGGATG GGAGATTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_937799.1
    CDS214..732
    Translation

    Target ORF information:

    RefSeq Version NM_198156.2
    Organism Homo sapiens(human)
    Definition Homo sapiens von Hippel-Lindau tumor suppressor (VHL), transcript variant 2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_198156.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGCCCCGGA GGGCGGAGAA CTGGGACGAG GCCGAGGTAG GCGCGGAGGA GGCAGGCGTC 
    GAAGAGTACG GCCCTGAAGA AGACGGCGGG GAGGAGTCGG GCGCCGAGGA GTCCGGCCCG
    GAAGAGTCCG GCCCGGAGGA ACTGGGCGCC GAGGAGGAGA TGGAGGCCGG GCGGCCGCGG
    CCCGTGCTGC GCTCGGTGAA CTCGCGCGAG CCCTCCCAGG TCATCTTCTG CAATCGCAGT
    CCGCGCGTCG TGCTGCCCGT ATGGCTCAAC TTCGACGGCG AGCCGCAGCC CTACCCAACG
    CTGCCGCCTG GCACGGGCCG CCGCATCCAC AGCTACCGAG TGTATACTCT GAAAGAGCGA
    TGCCTCCAGG TTGTCCGGAG CCTAGTCAAG CCTGAGAATT ACAGGAGACT GGACATCGTC
    AGGTCGCTCT ACGAAGATCT GGAAGACCAC CCAAATGTGC AGAAAGACCT GGAGCGGCTG
    ACACAGGAGC GCATTGCACA TCAACGGATG GGAGATTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu61302
    Clone ID Related Accession (Same CDS sequence) NM_001354723.2 , NM_001354723.1
    Accession Version NM_001354723.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 582bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-15
    Organism Homo sapiens(human)
    Product von Hippel-Lindau disease tumor suppressor isoform 3
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC034193.5. On Jun 2, 2019 this sequence version replaced NM_001354723.1. Transcript Variant: This variant (3) lacks an alternate in-frame exon and contains another alternate exon compared to variant 1. The resulting isoform (3) has a shorter and distinct C-terminus compared to variant 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.136882.1, SRR1163658.455261.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA2145893 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGCCCCGGA GGGCGGAGAA CTGGGACGAG GCCGAGGTAG GCGCGGAGGA GGCAGGCGTC 
    GAAGAGTACG GCCCTGAAGA AGACGGCGGG GAGGAGTCGG GCGCCGAGGA GTCCGGCCCG
    GAAGAGTCCG GCCCGGAGGA ACTGGGCGCC GAGGAGGAGA TGGAGGCCGG GCGGCCGCGG
    CCCGTGCTGC GCTCGGTGAA CTCGCGCGAG CCCTCCCAGG TCATCTTCTG CAATCGCAGT
    CCGCGCGTCG TGCTGCCCGT ATGGCTCAAC TTCGACGGCG AGCCGCAGCC CTACCCAACG
    CTGCCGCCTG GCACGGGCCG CCGCATCCAC AGCTACCGAG TCCTCATGAC TCCAGTGGGC
    CAGTTCTGCG TAGTCCCTGC CCTCGTGGAG AACACATTCC TCCTGGGGAG ACTGACAGAT
    GCAAAGACAG GAACAAGCCA GGGTCATGTT GGCGCCGGAA GAGCCGACCG TGTGTGGCGT
    GGGAAATTGA CTTACCTGCC TGCTGGGAGA TGGAGGGGTT GCGGTTGTGT GGTTTCAGTT
    AAGGAGCACT TCCCGGAGAA GGAAGAGAGC AGGATGGAGT AG

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001341652.1
    CDS71..652
    Translation

    Target ORF information:

    RefSeq Version NM_001354723.2
    Organism Homo sapiens(human)
    Definition Homo sapiens von Hippel-Lindau tumor suppressor (VHL), transcript variant 3, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001354723.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGCCCCGGA GGGCGGAGAA CTGGGACGAG GCCGAGGTAG GCGCGGAGGA GGCAGGCGTC 
    GAAGAGTACG GCCCTGAAGA AGACGGCGGG GAGGAGTCGG GCGCCGAGGA GTCCGGCCCG
    GAAGAGTCCG GCCCGGAGGA ACTGGGCGCC GAGGAGGAGA TGGAGGCCGG GCGGCCGCGG
    CCCGTGCTGC GCTCGGTGAA CTCGCGCGAG CCCTCCCAGG TCATCTTCTG CAATCGCAGT
    CCGCGCGTCG TGCTGCCCGT ATGGCTCAAC TTCGACGGCG AGCCGCAGCC CTACCCAACG
    CTGCCGCCTG GCACGGGCCG CCGCATCCAC AGCTACCGAG TCCTCATGAC TCCAGTGGGC
    CAGTTCTGCG TAGTCCCTGC CCTCGTGGAG AACACATTCC TCCTGGGGAG ACTGACAGAT
    GCAAAGACAG GAACAAGCCA GGGTCATGTT GGCGCCGGAA GAGCCGACCG TGTGTGGCGT
    GGGAAATTGA CTTACCTGCC TGCTGGGAGA TGGAGGGGTT GCGGTTGTGT GGTTTCAGTT
    AAGGAGCACT TCCCGGAGAA GGAAGAGAGC AGGATGGAGT AG

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu61302
    Clone ID Related Accession (Same CDS sequence) NM_001354723.2 , NM_001354723.1
    Accession Version NM_001354723.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 582bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-03-11
    Organism Homo sapiens(human)
    Product von Hippel-Lindau disease tumor suppressor isoform 3
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC034193.5 and HY256093.1. Transcript Variant: This variant (3) lacks an alternate in-frame exon and contains another alternate exon compared to variant 1. The resulting isoform (3) has a shorter and distinct C-terminus compared to variant 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.455261.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA2145893 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGCCCCGGA GGGCGGAGAA CTGGGACGAG GCCGAGGTAG GCGCGGAGGA GGCAGGCGTC 
    GAAGAGTACG GCCCTGAAGA AGACGGCGGG GAGGAGTCGG GCGCCGAGGA GTCCGGCCCG
    GAAGAGTCCG GCCCGGAGGA ACTGGGCGCC GAGGAGGAGA TGGAGGCCGG GCGGCCGCGG
    CCCGTGCTGC GCTCGGTGAA CTCGCGCGAG CCCTCCCAGG TCATCTTCTG CAATCGCAGT
    CCGCGCGTCG TGCTGCCCGT ATGGCTCAAC TTCGACGGCG AGCCGCAGCC CTACCCAACG
    CTGCCGCCTG GCACGGGCCG CCGCATCCAC AGCTACCGAG TCCTCATGAC TCCAGTGGGC
    CAGTTCTGCG TAGTCCCTGC CCTCGTGGAG AACACATTCC TCCTGGGGAG ACTGACAGAT
    GCAAAGACAG GAACAAGCCA GGGTCATGTT GGCGCCGGAA GAGCCGACCG TGTGTGGCGT
    GGGAAATTGA CTTACCTGCC TGCTGGGAGA TGGAGGGGTT GCGGTTGTGT GGTTTCAGTT
    AAGGAGCACT TCCCGGAGAA GGAAGAGAGC AGGATGGAGT AG

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001341652.1
    CDS214..795
    Translation

    Target ORF information:

    RefSeq Version NM_001354723.1
    Organism Homo sapiens(human)
    Definition Homo sapiens von Hippel-Lindau tumor suppressor (VHL), transcript variant 3, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001354723.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGCCCCGGA GGGCGGAGAA CTGGGACGAG GCCGAGGTAG GCGCGGAGGA GGCAGGCGTC 
    GAAGAGTACG GCCCTGAAGA AGACGGCGGG GAGGAGTCGG GCGCCGAGGA GTCCGGCCCG
    GAAGAGTCCG GCCCGGAGGA ACTGGGCGCC GAGGAGGAGA TGGAGGCCGG GCGGCCGCGG
    CCCGTGCTGC GCTCGGTGAA CTCGCGCGAG CCCTCCCAGG TCATCTTCTG CAATCGCAGT
    CCGCGCGTCG TGCTGCCCGT ATGGCTCAAC TTCGACGGCG AGCCGCAGCC CTACCCAACG
    CTGCCGCCTG GCACGGGCCG CCGCATCCAC AGCTACCGAG TCCTCATGAC TCCAGTGGGC
    CAGTTCTGCG TAGTCCCTGC CCTCGTGGAG AACACATTCC TCCTGGGGAG ACTGACAGAT
    GCAAAGACAG GAACAAGCCA GGGTCATGTT GGCGCCGGAA GAGCCGACCG TGTGTGGCGT
    GGGAAATTGA CTTACCTGCC TGCTGGGAGA TGGAGGGGTT GCGGTTGTGT GGTTTCAGTT
    AAGGAGCACT TCCCGGAGAA GGAAGAGAGC AGGATGGAGT AG

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.