Hsd17b2 cDNA ORF clone, Rattus norvegicus(Norway rat)
| Gene Symbol | Hsd17b2 |
| Entrez Gene ID | 79243 |
| Full Name | hydroxysteroid (17-beta) dehydrogenase 2 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome | |
| Summary | 17-beta hydroxysteroid enzyme that regulates the biological activity of sex hormones, including estrogen and androgens [RGD, Feb 2006]. |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_024391.1 | NP_077367.1 | estradiol 17-beta-dehydrogenase 2 |
| Homo sapiens (human) | HSD17B2 | NP_002144.1 |
| Pan troglodytes (chimpanzee) | HSD17B2 | XP_511130.2 |
| Danio rerio (zebrafish) | hsd17b2 | NP_001035278.1 |
| Bos taurus (cattle) | HSD17B2 | NP_001069194.1 |
| Rattus norvegicus (Norway rat) | Hsd17b2 | NP_077367.1 |
| Xenopus tropicalis (tropical clawed frog) | hsd17b2 | XP_002934996.1 |
| LOC714282 | XP_001111794.2 | |
| Mus musculus (house mouse) | Hsd17b2 | NP_032316.2 |
| Canis lupus familiaris (dog) | HSD17B2 | XP_005620709.1 |
| Gallus gallus (chicken) | HSD17B2 | XP_414168.4 |
Related articles in PubMed
Gestational protein restriction reduces expression of Hsd17b2 in rat placental labyrinth.
Gao H, Yallampalli U, Yallampalli C
Biology of reproduction87(3)68(2012 Sep)
Lactational exposure to hexavalent chromium delays puberty by impairing ovarian development, steroidogenesis and pituitary hormone synthesis in developing Wistar rats.
Banu SK, Samuel JB, Arosh JA, Burghardt RC, Aruldhas MM
Toxicology and applied pharmacology232(2)180-9(2008 Oct)
Placenta defects and embryonic lethality resulting from disruption of mouse hydroxysteroid (17-beta) dehydrogenase 2 gene.
Rantakari P, Strauss L, Kiviranta R, Lagerbohm H, Paviala J, Holopainen I, Vainio S, Pakarinen P, Poutanen M
Molecular endocrinology (Baltimore, Md.)22(3)665-75(2008 Mar)
Regulation of 17-beta hydroxysteroid dehydrogenase type 2 in human placental endothelial cells.
Su EJ, Cheng YH, Chatterton RT, Lin ZH, Yin P, Reierstad S, Innes J, Bulun SE
Biology of reproduction77(3)517-25(2007 Sep)
Aging reduces the efficacy of estrogen substitution to attenuate cardiac hypertrophy in female spontaneously hypertensive rats.
Jazbutyte V, Hu K, Kruchten P, Bey E, Maier SK, Fritzemeier KH, Prelle K, Hegele-Hartung C, Hartmann RW, Neyses L, Ertl G, Pelzer T
Hypertension (Dallas, Tex. : 1979)48(4)579-86(2006 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Gestational protein restriction reduces expression of Hsd17b2 in rat placental labyrinth.
Title: Gestational protein restriction reduces expression of Hsd17b2 in rat placental labyrinth.
The following Hsd17b2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hsd17b2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa07020 | |
| Clone ID Related Accession (Same CDS sequence) | NM_024391.1 | |
| Accession Version | NM_024391.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1146bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-24 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | estradiol 17-beta-dehydrogenase 2 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X91234.1. ##Evidence-Data-START## Transcript exon combination :: X91234.1, BC088134.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689597, SAMEA2689598 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGAACCCGT TTTCCTCTGA GTCAGCATGG CTCTGCTTGA CTGCCACTGC GGTGCTGGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_077367.1 |
| CDS | 47..1192 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_024391.1 |
ORF Insert Sequence:
1 | ATGAACCCGT TTTCCTCTGA GTCAGCATGG CTCTGCTTGA CTGCCACTGC GGTGCTGGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
Gestational protein restriction reduces expression of Hsd17b2 in rat placental labyrinth. |
|
Lactational exposure to hexavalent chromium delays puberty by impairing ovarian development, steroidogenesis and pituitary hormone synthesis in developing Wistar rats. |
|
Placenta defects and embryonic lethality resulting from disruption of mouse hydroxysteroid (17-beta) dehydrogenase 2 gene. |
|
Regulation of 17-beta hydroxysteroid dehydrogenase type 2 in human placental endothelial cells. |
|
Aging reduces the efficacy of estrogen substitution to attenuate cardiac hypertrophy in female spontaneously hypertensive rats. |
