This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the ultrahigh sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. Alternative haplotypes of this gene are represented in the GRCh38 reference genome assembly. [provided by RefSeq, Dec 2015].
The following KRTAP9-9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KRTAP9-9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Michael Rogers. The reference sequence was derived from AC006070.1. On Mar 19, 2010 this sequence version replaced NM_030975.1.
Transcript Variant: This variant (KRTAP9.5) lacks an in-frame segment of the 5' coding region and includes a base change in the 3' UTR, compared to variant KRTAP9.9. The encoded isoform (KRTAP9.5) is 5 aa shorter than isoform KRTAP9.9. This variant is produced from the primary chromosome 17 assembly unit of the GRCh38 reference genome assembly.
Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. COMPLETENESS: complete on the 3' end.
Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ406951.1 and AC209539.6.
Transcript Variant: This variant (KRTAP9.9) represents the longer transcript and encodes the longer isoform (KRTAP9.9). It is produced from an alternate haplotype that is represented by the ALT_REF_LOCI_1 assembly unit of the GRCh38 reference genome assembly.
RefSeq Select criteria :: based on expression, longest protein
COMPLETENESS: complete on the 3' end.