LAGE3 cDNA ORF clone, Homo sapiens(human)

  • Gene

  • Clones

  • gRNAs

The following LAGE3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LAGE3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu05208 NM_006014.4
Latest version!
Homo sapiens L antigen family member 3 (LAGE3), mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$49.50-$69.30
$99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

  • Reference Sequences (Refseq)
    CloneID OHu05208
    Clone ID Related Accession (Same CDS sequence) NM_006014.4
    Accession Version NM_006014.4 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 432bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-10-09
    Organism Homo sapiens(human)
    Product EKC/KEOPS complex subunit LAGE3
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC015744.1 and BQ649305.1. On Sep 12, 2013 this sequence version replaced NM_006014.3. ##Evidence-Data-START## Transcript exon combination :: BC015744.1, SRR1163658.189391.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2145743, SAMEA2148093 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    ATGCGGGACG CGGATGCAGA CGCAGGCGGA GGCGCTGACG GCGGGGATGG CCGGGGTGGC 
    CACAGCTGCC GCGGGGGCGT GGACACAGCC GCAGCTCCGG CCGGTGGAGC TCCCCCAGCG
    CACGCGCCAG GTCCGGGCAG AGACGCCGCG TCTGCGGCCA GGGGGTCACG AATGCGGCCG
    CACATATTCA CCCTCAGCGT GCCTTTCCCG ACCCCCTTGG AGGCGGAAAT CGCCCATGGG
    TCCCTGGCAC CAGATGCCGA GCCCCACCAA AGGGTGGTTG GGAAGGATCT CACAGTGAGT
    GGCAGGATCC TGGTCGTCCG CTGGAAAGCT GAAGACTGTC GCCTGCTCCG AATTTCCGTC
    ATCAACTTTC TTGACCAGCT TTCCCTGGTG GTGCGGACCA TGCAGCGCTT TGGGCCCCCC
    GTTTCCCGCT AA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_006005.2
    CDS343..774
    Translation

    Target ORF information:

    RefSeq Version NM_006014.4
    Organism Homo sapiens(human)
    Definition Homo sapiens L antigen family member 3 (LAGE3), mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_006014.4

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    ATGCGGGACG CGGATGCAGA CGCAGGCGGA GGCGCTGACG GCGGGGATGG CCGGGGTGGC 
    CACAGCTGCC GCGGGGGCGT GGACACAGCC GCAGCTCCGG CCGGTGGAGC TCCCCCAGCG
    CACGCGCCAG GTCCGGGCAG AGACGCCGCG TCTGCGGCCA GGGGGTCACG AATGCGGCCG
    CACATATTCA CCCTCAGCGT GCCTTTCCCG ACCCCCTTGG AGGCGGAAAT CGCCCATGGG
    TCCCTGGCAC CAGATGCCGA GCCCCACCAA AGGGTGGTTG GGAAGGATCT CACAGTGAGT
    GGCAGGATCC TGGTCGTCCG CTGGAAAGCT GAAGACTGTC GCCTGCTCCG AATTTCCGTC
    ATCAACTTTC TTGACCAGCT TTCCCTGGTG GTGCGGACCA TGCAGCGCTT TGGGCCCCCC
    GTTTCCCGCT AA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

  • PubMed

    Mutations in KEOPS-complex genes cause nephrotic syndrome with primary microcephaly.
    Nature genetics49(10)1529-1538(2017 Oct)
    Braun DA,Rao J,Mollet G,Schapiro D,Daugeron MC,Tan W,Gribouval O,Boyer O,Revy P,Jobst-Schwan T,Schmidt JM,Lawson JA,Schanze D,Ashraf S,Ullmann JFP,Hoogstraten CA,Boddaert N,Collinet B,Martin G,Liger D,Lovric S,Furlano M,Guerrera IC,Sanchez-Ferras O,Hu JF,Boschat AC,Sanquer S,Menten B,Vergult S,De Rocker N,Airik M,Hermle T,Shril S,Widmeier E,Gee HY,Choi WI,Sadowski CE,Pabst WL,Warejko JK,Daga A,Basta T,Matejas V,Scharmann K,Kienast SD,Behnam B,Beeson B,Begtrup A,Bruce M,Ch'ng GS,Lin SP,Chang JH,Chen CH,Cho MT,Gaffney PM,Gipson PE,Hsu CH,Kari JA,Ke YY,Kiraly-Borri C,Lai WM,Lemyre E,Littlejohn RO,Masri A,Moghtaderi M,Nakamura K,Ozaltin F,Praet M,Prasad C,Prytula A,Roeder ER,Rump P,Schnur RE,Shiihara T,Sinha MD,Soliman NA,Soulami K,Sweetser DA,Tsai WH,Tsai JD,Topaloglu R,Vester U,Viskochil DH,Vatanavicharn N,Waxler JL,Wierenga KJ,Wolf MTF,Wong SN,Leidel SA,Truglio G,Dedon PC,Poduri A,Mane S,Lifton RP,Bouchard M,Kannu P,Chitayat D,Magen D,Callewaert B,van Tilbeurgh H,Zenker M,Antignac C,Hildebrandt F


    Architecture of the human interactome defines protein communities and disease networks.
    Nature545(7655)505-509(2017 05)
    Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW


    Proteomic analysis of the human KEOPS complex identifies C14ORF142 as a core subunit homologous to yeast Gon7.
    Nucleic acids research45(2)805-817(2017 Jan)
    Wan LC,Maisonneuve P,Szilard RK,Lambert JP,Ng TF,Manczyk N,Huang H,Laister R,Caudy AA,Gingras AC,Durocher D,Sicheri F


    An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
    Nature communications711491(2016 May)
    Boldt K,van Reeuwijk J,Lu Q,Koutroumpas K,Nguyen TM,Texier Y,van Beersum SE,Horn N,Willer JR,Mans DA,Dougherty G,Lamers IJ,Coene KL,Arts HH,Betts MJ,Beyer T,Bolat E,Gloeckner CJ,Haidari K,Hetterschijt L,Iaconis D,Jenkins D,Klose F,Knapp B,Latour B,Letteboer SJ,Marcelis CL,Mitic D,Morleo M,Oud MM,Riemersma M,Rix S,Terhal PA,Toedt G,van Dam TJ,de Vrieze E,Wissinger Y,Wu KM,Apic G,Beales PL,Blacque OE,Gibson TJ,Huynen MA,Katsanis N,Kremer H,Omran H,van Wijk E,Wolfrum U,Kepes F,Davis EE,Franco B,Giles RH,Ueffing M,Russell RB,Roepman R,


    The human EKC/KEOPS complex is recruited to Cullin2 ubiquitin ligases by the human tumour antigen PRAME.
    PloS one7(8)e42822(2012)
    Costessi A,Mahrour N,Sharma V,Stunnenberg R,Stoel MA,Tijchon E,Conaway JW,Conaway RC,Stunnenberg HG


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