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Cadps cDNA ORF clone, Rattus norvegicus(Norway rat)

Summary

Gene Symbol Cadps
Entrez Gene ID 26989
Full Name calcium dependent secretion activator
Synonyms Caps,Caps1,Caps2
General protein information
Preferred Names

calcium dependent secretion activator

Names

calcium-dependent secretion activator 1
CAPS-1
Ca++-dependent secretion activator
Ca2+ dependent secretion activator
Ca2+-dependent activator protein
Ca<2+-dependent activator protein for secretion
calcium-dependent activator protein for secretion 1
rCAPS
Gene Type protein-coding
Organism Rattus norvegicus(Norway rat)
Genome

15

15p15
Summary plays a role in calcium ion-dependent regulated exocytosis in neuroendocrine cells [RGD, Feb 2006].

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_013219.1 NP_037351.1 calcium-dependent secretion activator 1

Pathways from BioSystems


Homologies


Pan troglodytes (chimpanzee) CADPS XP_001174527.1
Danio rerio (zebrafish) cadpsa XP_005155902.1
Mus musculus (house mouse) Cadps NP_001036082.1
Rattus norvegicus (Norway rat) Cadps NP_037351.1
Gallus gallus (chicken) CADPS XP_001233835.1
Drosophila melanogaster (fruit fly) Caps NP_001245439.1
Xenopus tropicalis (tropical clawed frog) cadps NP_001096182.1
Homo sapiens (human) CADPS NP_003707.2
Canis lupus familiaris (dog) CADPS XP_848403.2
Caenorhabditis elegans (roundworm) unc-31 NP_001255664.1
Bos taurus (cattle) CADPS NP_001069488.1
Danio rerio (zebrafish) cadpsb XP_005166165.1
LOC703270 XP_001091569.2

Gene Ontology


Bibliography

Related articles in PubMed

The Vesicle Priming Factor CAPS Functions as a Homodimer via C2 Domain Interactions to Promote Regulated Vesicle Exocytosis.
Petrie M, Esquibel J, Kabachinski G, Maciuba S, Takahashi H, Edwardson JM, Martin TF
The Journal of biological chemistry291(40)21257-21270(2016 Sep)

Resident CAPS on dense-core vesicles docks and primes vesicles for fusion.
Kabachinski G, Kielar-Grevstad DM, Zhang X, James DJ, Martin TF
Molecular biology of the cell27(4)654-68(2016 Feb)

CAPS-1 promotes fusion competence of stationary dense-core vesicles in presynaptic terminals of mammalian neurons.
Farina M, van de Bospoort R, He E, Persoon CM, van Weering JR, Broeke JH, Verhage M, Toonen RF
eLife4(2015 Feb)

The morphological and molecular nature of synaptic vesicle priming at presynaptic active zones.
Imig C, Min SW, Krinner S, Arancillo M, Rosenmund C, S?dhof TC, Rhee J, Brose N, Cooper BH
Neuron84(2)416-31(2014 Oct)

CAPS and Munc13 utilize distinct PIP2-linked mechanisms to promote vesicle exocytosis.
Kabachinski G, Yamaga M, Kielar-Grevstad DM, Bruinsma S, Martin TF
Molecular biology of the cell25(4)508-21(2014 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The unique tandem C2-PH domain of CAPS may serve as a PI(4,5)P2-triggered switch for dimerization. CAPS dimerization may be coupled to oligomeric SNARE complex assembly for vesicle docking and priming.
Title: The Vesicle Priming Factor CAPS Functions as a Homodimer via C2 Domain Interactions to Promote Regulated Vesicle Exocytosis.

results indicate that dense-core vesicles carry CAPS to sites of exocytosis, where CAPS promotes vesicle docking and fusion competence, probably by initiating SNARE complex assembly.
Title: Resident CAPS on dense-core vesicles docks and primes vesicles for fusion.

Transport vesicle fusion into PIP2-rich membrane domains is facilitated by sequential PIP2-dependent activation of CAPS and PIP2-dependent recruitment of Munc13.
Title: CAPS and Munc13 utilize distinct PIP2-linked mechanisms to promote vesicle exocytosis.

CAPS1 binds to the full-length of cytoplasmic syntaxin-1 with preference to its "open" conformation, whereas Munc13-1 binds to the first 80 N-terminal residues of syntaxin-1.
Title: Calcium-dependent activator protein for secretion 1 (CAPS1) binds to syntaxin-1 in a distinct mode from Munc13-1.

The results show that Munc13 homology domain-1 is a SNARE-binding domain and that SNARE protein binding is essential for CAPS function in dense-core vesicle exocytosis.
Title: Munc13 homology domain-1 in CAPS/UNC31 mediates SNARE binding required for priming vesicle exocytosis.

The following Cadps gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cadps cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
ORa42440 NM_013219.1
Latest version!		 Rattus norvegicus calcium dependent secretion activator (Cadps), mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $643.30
$919.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID ORa42440
Clone ID Related Accession (Same CDS sequence) NM_013219.1
Accession Version NM_013219.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 3870bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-09-22
Organism Rattus norvegicus(Norway rat)
Product calcium-dependent secretion activator 1
Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U16802.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U16802.1 [ECO:0000332] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
ATGCTGGACC CTTCGTCCAG CGAAGAGGAA TCGGATGAGA TCCTGGAAGA GGAGAGCGGC 
AAGGAGGTGC TGGGCTCGGC CGCGTCCGGA GCGCGCCTGT CTCCAAGCCG CACCAACGAG 
GGCTCGGCGG GCAGCGCCGG CATGGGGGGC AGTGGCGCCG GGGCCGGGGT GGGCGCCGGC 
GGCGGTGGGG GTAGCGGCGC GAGCAGCGGC GGCGGGGCCG GGGGGCTGCA GCCCAGCAGC 
CGCGCCGGCG GCGGCCGGCC CTCCAGCCCC AGCCCGTCGG TGGTGAGCGA GAAGGAGAAG 
GAAGAGTTGG AGCGGCTGCA GAAGGAAGAG GAGGAGAGGA AGAAGAGGCT GCAGCTGTAC 
GTGTTCGTGA TGCGCTGCAT TGCCTACCCC TTCAACGCCA AGCAGCCCAC CGACATGGCT 
CGGCGGCCAA GGAAGATCAG CAAACAGCAG CTGCAGACTG TCAAGGACCG ATTCCAGGCT 
TTCCTCAATG GGGAGACCCA AATCGTGGCA GATGAAGCCT TTATGAATGC TGTCCAGAGC 
TACTATGAGG TGTTTCTCAA GAGTGACCGT GTGGCCCGCA TGGTACAGAG TGGGGGCTGC 
TCAGCCAACG ACTCTCGGGA GGTCTTCAAG AAACACATCG AGAAGAGGGT ACGCAGCCTA 
CCTGAGATTG ATGGCCTCAG CAAGGAGACT GTGCTAAGCT CCTGGATGGC TAAGTTTGAC 
GCCATCTACC GTGGTGAGGA GGACCCCAGG AAGCAGCAAG CCCGGATGAC AGCCAGTGCA 
GCTTCTGAGT TGATTCTGAG CAAGGAACAG CTCTATGAGA TGTTCCAGAA CATTCTTGGG 
ATCAAGAAAT TTGAACATCA ACTCCTATAT AATGCGTGTC AGCTGGACAA TCCAGATGAG 
CAGGCAGCCC AGATCAGACG AGAGCTGGAC GGACGTCTCC AAATGGCAGA CCAAATAGCC 
AGGGAACGCA AATTTCCTAA GTTCGTATCC AAAGAAATGG AAAATATGTA CATCGAGGAG 
CTGAAGTCCT CCGTCAACCT ACTCATGGCC AACTTGGAGA GCATGCCGGT GTCCAAGGGT 
GGAGAGTTCA AGCTGCAGAA ACTGAAACGC AGTCACAACG CGTCCATCAT TGACATGGGT 
GAGGAGAGCG AGAACCAGCT GTCCAAGTCG GATGTCCTGC TGTCCTTCTC CTTGGAGGTT 
GTCATCATGG AAGTCCAAGG CCTTAAGTCC TTGGCTCCAA ACCGAATCGT GTACTGCACA 
ATGGAGGTGG AGGGTGGAGA GAAACTTCAG ACTGATCAAG CAGAGGCTTC TAAACCAACC 
TGGGGCACTC AAGGCGACTT CTCTACAACC CACGCGCTGC CAGCTGTTAA AGTAAAGCTA 
TTCACAGAGA GCACTGGTGT CCTGGCCTTG GAAGACAAGG AACTCGGGCG GGTTATCCTC 
CATCCCACCC CAAACAGCCC CAAACAATCC GAGTGGCACA AAATGACAGT CTCCAAAAAC 
TGCCCCGATC AAGACCTCAA AATCAAACTC GCTGTCCGAA TGGATAAGCC TCAAAACATG 
AAGCACTCTG GGTACTTATG GACCATTGGT AAGAATGTGT GGAAGAGGTG GAAGAAAAGG 
TTCTTTGTGT TGGTGCAGGT CAGCCAGTAC ACTTTTGCCA TGTGCAGCTA TCGAGAAAAG 
AAAGCAGAAC CTCAGGAACT CCTACAGCTG GATGGCTACA CCGTGGATTA CACCGACCCT 
CAGCCAGGTT TGGAGGGTGG CCGAGCCTTC TTCAATGCAG TCAAAGAAGG AGACACGGTG 
ATATTTGCCA GTGACGATGA GCAAGATCGA ATCCTGTGGG TCCAAGCTAT GTACAGGGCC 
ACCGGGCAGT CGCACAAACC TGTGCCCCCT ACCCAGGTGC AGAAGCTCAA GCCAAGGGCG 
GAAACGTGCC TCAGCATGGA TGCCCCCATC TCCCAGTTTT ACGCAGATAG AGCTCAAAAG 
CATGGCATGG ATGAATTTAT CTCGTCCAAC CCCTGTAACT TTGACCACGC TTCCCTCTTT 
GAGATGGTAC AGCGGCTGAC TTTGGATCAC AGACTAAACG ATTCCTATTC TTGCCTGGGC 
TGGTTCAGTC CTGGCCAGGT GTTTGTGTTA GACGAGTACT GCGCTCGGAA TGGAGTCCGA 
GGATGTCATC GGCATCTCTG TTACCTTAGA GACTTGCTGG AACGGGCAGA AAATGGCGCC 
ATGATCGACC CCACGCTTCT TCATTACAGC TTTGCCTTCT GCGCATCCCA TGTCCACGGG 
AACAGGCCTG ATGGAATCGG AACTGTGACT GTTGAAGAAA AAGAGCGCTT TGAAGAAATC 
AAAGAGAGAC TCCGAGTTCT GCTGGAAAAT CAAATTACAC ATTTCAGGTA CTGCTTTCCG 
TTTGGTCGAC CTGAAGGTGC TTTGAAAGCG ACTCTCTCAC TTTTGGAACG GGTTTTGATG 
AAAGATATTG TCACTCCAGT ACCCCAAGAG GAGGTCAAAA CTGTCATCCG TAAATGCCTA 
GAGCAGGCTG CTCTAGTCAA CTACTCTCGC CTATCTGAGT ATGCCAAAAT CGAAGAAAAT 
GTAGGCCGCT TAATCACTCC CGCCAAAAAG CTCGAAGACA CAATCCGTCT TGCTGAACTA 
GTCATTGAAG TGCTGCAACA AAACGAAGAG CACCACGCCG AGGCCTTTGC GTGGTGGTCA 
GACTTAATGG TGGAGCACGC GGAGACGTTC CTGTCACTCT TTGCAGTGGA CATGGATGCA 
GCATTAGAGG TGCAACCCCC AGACACGTGG GACAGTTTCC CACTCTTCCA GCTGCTGAAT 
GACTTTCTCC GTACAGACTA TAACTTGTGC AATGGAAAGT TTCACAAACA CCTGCAGGAT 
CTGTTCGCCC CACTCGTTGT TAGATACGTG GATCTGATGG AGTCCTCAAT TGCACAATCT 
ATCCACAGGG GCTTTGAGCG GGAGTCATGG GAACCAGTCA ATAACGGATC GGGTACATCA 
GAAGATTTGT TCTGGAAACT TGATGCCCTT CAGACTTTCA TCCGTGACCT ACACTGGCCT 
GAGGAAGAGT TTGGAAAGCA CTTAGAGCAG CGGCTAAAAC TAATGGCAAG CGACATGATT 
GAGTCCTGCG TCAAGAGAAC CAGGATTGCA TTTGAAGTTA AGCTGCAAAA AACCAGTCGA 
TCAACAGATT TTCGAGTCCC ACAGTCAATA TGCACCATGT TTAATGTTAT GGTTGATGCC 
AAAGCTCAAT CAACAAAACT TTGCAGCATG GAAATGGGCC AGGAGCATCA ATACCATTCA 
AAAATAGACG AACTAATTGA AGAAACCGTT AAGGAAATGA TCACACTCTT GGTGGCAAAG 
TTTGTAACTA TATTGGAAGG CGTACTGGCA AAGTTATCCA GATACGACGA GGGGACTTTG 
TTTTCTTCGT TTCTGTCATT TACGGTGAAG GCGGCATCTA AGTATGTGGA CGTACCTAAA 
CCCGGGATGG ATGTGGCCGA CGCCTACGTG ACTTTCGTCC GCCACTCTCA GGATGTCCTT 
CGTGATAAGG TCAATGAGGA GATGTATATA GAAAGGTTAT TTGATCAATG GTACAACAGC 
TCCATGAACG TCATCTGCAC CTGGCTGACC GACCGGATGG ACCTCCAGCT TCACATTTAT 
CAGCTGAAAA CACTAATTAG GATGGTAAAG AAAACCTACA GAGATTTCCG ATTGCAAGGG 
GTCCTGGATT CCACCTTAAA CAGCAAGACC TATGAGACCA TTCGAAATCG GCTCACTGTA 
GAGGAACGTA CCGCGTCCGT GAGTGAGGGA GGGGGCTTGC AAGGCATCAG CATGAAGGAC 
AGTGACGAGG AAGATGAAGA AGACGACTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_037351.1
CDS62..3931
Translation

Target ORF information:

RefSeq Version NM_013219.1
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus calcium dependent secretion activator (Cadps), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_013219.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
ATGCTGGACC CTTCGTCCAG CGAAGAGGAA TCGGATGAGA TCCTGGAAGA GGAGAGCGGC 
AAGGAGGTGC TGGGCTCGGC CGCGTCCGGA GCGCGCCTGT CTCCAAGCCG CACCAACGAG 
GGCTCGGCGG GCAGCGCCGG CATGGGGGGC AGTGGCGCCG GGGCCGGGGT GGGCGCCGGC 
GGCGGTGGGG GTAGCGGCGC GAGCAGCGGC GGCGGGGCCG GGGGGCTGCA GCCCAGCAGC 
CGCGCCGGCG GCGGCCGGCC CTCCAGCCCC AGCCCGTCGG TGGTGAGCGA GAAGGAGAAG 
GAAGAGTTGG AGCGGCTGCA GAAGGAAGAG GAGGAGAGGA AGAAGAGGCT GCAGCTGTAC 
GTGTTCGTGA TGCGCTGCAT TGCCTACCCC TTCAACGCCA AGCAGCCCAC CGACATGGCT 
CGGCGGCCAA GGAAGATCAG CAAACAGCAG CTGCAGACTG TCAAGGACCG ATTCCAGGCT 
TTCCTCAATG GGGAGACCCA AATCGTGGCA GATGAAGCCT TTATGAATGC TGTCCAGAGC 
TACTATGAGG TGTTTCTCAA GAGTGACCGT GTGGCCCGCA TGGTACAGAG TGGGGGCTGC 
TCAGCCAACG ACTCTCGGGA GGTCTTCAAG AAACACATCG AGAAGAGGGT ACGCAGCCTA 
CCTGAGATTG ATGGCCTCAG CAAGGAGACT GTGCTAAGCT CCTGGATGGC TAAGTTTGAC 
GCCATCTACC GTGGTGAGGA GGACCCCAGG AAGCAGCAAG CCCGGATGAC AGCCAGTGCA 
GCTTCTGAGT TGATTCTGAG CAAGGAACAG CTCTATGAGA TGTTCCAGAA CATTCTTGGG 
ATCAAGAAAT TTGAACATCA ACTCCTATAT AATGCGTGTC AGCTGGACAA TCCAGATGAG 
CAGGCAGCCC AGATCAGACG AGAGCTGGAC GGACGTCTCC AAATGGCAGA CCAAATAGCC 
AGGGAACGCA AATTTCCTAA GTTCGTATCC AAAGAAATGG AAAATATGTA CATCGAGGAG 
CTGAAGTCCT CCGTCAACCT ACTCATGGCC AACTTGGAGA GCATGCCGGT GTCCAAGGGT 
GGAGAGTTCA AGCTGCAGAA ACTGAAACGC AGTCACAACG CGTCCATCAT TGACATGGGT 
GAGGAGAGCG AGAACCAGCT GTCCAAGTCG GATGTCCTGC TGTCCTTCTC CTTGGAGGTT 
GTCATCATGG AAGTCCAAGG CCTTAAGTCC TTGGCTCCAA ACCGAATCGT GTACTGCACA 
ATGGAGGTGG AGGGTGGAGA GAAACTTCAG ACTGATCAAG CAGAGGCTTC TAAACCAACC 
TGGGGCACTC AAGGCGACTT CTCTACAACC CACGCGCTGC CAGCTGTTAA AGTAAAGCTA 
TTCACAGAGA GCACTGGTGT CCTGGCCTTG GAAGACAAGG AACTCGGGCG GGTTATCCTC 
CATCCCACCC CAAACAGCCC CAAACAATCC GAGTGGCACA AAATGACAGT CTCCAAAAAC 
TGCCCCGATC AAGACCTCAA AATCAAACTC GCTGTCCGAA TGGATAAGCC TCAAAACATG 
AAGCACTCTG GGTACTTATG GACCATTGGT AAGAATGTGT GGAAGAGGTG GAAGAAAAGG 
TTCTTTGTGT TGGTGCAGGT CAGCCAGTAC ACTTTTGCCA TGTGCAGCTA TCGAGAAAAG 
AAAGCAGAAC CTCAGGAACT CCTACAGCTG GATGGCTACA CCGTGGATTA CACCGACCCT 
CAGCCAGGTT TGGAGGGTGG CCGAGCCTTC TTCAATGCAG TCAAAGAAGG AGACACGGTG 
ATATTTGCCA GTGACGATGA GCAAGATCGA ATCCTGTGGG TCCAAGCTAT GTACAGGGCC 
ACCGGGCAGT CGCACAAACC TGTGCCCCCT ACCCAGGTGC AGAAGCTCAA GCCAAGGGCG 
GAAACGTGCC TCAGCATGGA TGCCCCCATC TCCCAGTTTT ACGCAGATAG AGCTCAAAAG 
CATGGCATGG ATGAATTTAT CTCGTCCAAC CCCTGTAACT TTGACCACGC TTCCCTCTTT 
GAGATGGTAC AGCGGCTGAC TTTGGATCAC AGACTAAACG ATTCCTATTC TTGCCTGGGC 
TGGTTCAGTC CTGGCCAGGT GTTTGTGTTA GACGAGTACT GCGCTCGGAA TGGAGTCCGA 
GGATGTCATC GGCATCTCTG TTACCTTAGA GACTTGCTGG AACGGGCAGA AAATGGCGCC 
ATGATCGACC CCACGCTTCT TCATTACAGC TTTGCCTTCT GCGCATCCCA TGTCCACGGG 
AACAGGCCTG ATGGAATCGG AACTGTGACT GTTGAAGAAA AAGAGCGCTT TGAAGAAATC 
AAAGAGAGAC TCCGAGTTCT GCTGGAAAAT CAAATTACAC ATTTCAGGTA CTGCTTTCCG 
TTTGGTCGAC CTGAAGGTGC TTTGAAAGCG ACTCTCTCAC TTTTGGAACG GGTTTTGATG 
AAAGATATTG TCACTCCAGT ACCCCAAGAG GAGGTCAAAA CTGTCATCCG TAAATGCCTA 
GAGCAGGCTG CTCTAGTCAA CTACTCTCGC CTATCTGAGT ATGCCAAAAT CGAAGAAAAT 
GTAGGCCGCT TAATCACTCC CGCCAAAAAG CTCGAAGACA CAATCCGTCT TGCTGAACTA 
GTCATTGAAG TGCTGCAACA AAACGAAGAG CACCACGCCG AGGCCTTTGC GTGGTGGTCA 
GACTTAATGG TGGAGCACGC GGAGACGTTC CTGTCACTCT TTGCAGTGGA CATGGATGCA 
GCATTAGAGG TGCAACCCCC AGACACGTGG GACAGTTTCC CACTCTTCCA GCTGCTGAAT 
GACTTTCTCC GTACAGACTA TAACTTGTGC AATGGAAAGT TTCACAAACA CCTGCAGGAT 
CTGTTCGCCC CACTCGTTGT TAGATACGTG GATCTGATGG AGTCCTCAAT TGCACAATCT 
ATCCACAGGG GCTTTGAGCG GGAGTCATGG GAACCAGTCA ATAACGGATC GGGTACATCA 
GAAGATTTGT TCTGGAAACT TGATGCCCTT CAGACTTTCA TCCGTGACCT ACACTGGCCT 
GAGGAAGAGT TTGGAAAGCA CTTAGAGCAG CGGCTAAAAC TAATGGCAAG CGACATGATT 
GAGTCCTGCG TCAAGAGAAC CAGGATTGCA TTTGAAGTTA AGCTGCAAAA AACCAGTCGA 
TCAACAGATT TTCGAGTCCC ACAGTCAATA TGCACCATGT TTAATGTTAT GGTTGATGCC 
AAAGCTCAAT CAACAAAACT TTGCAGCATG GAAATGGGCC AGGAGCATCA ATACCATTCA 
AAAATAGACG AACTAATTGA AGAAACCGTT AAGGAAATGA TCACACTCTT GGTGGCAAAG 
TTTGTAACTA TATTGGAAGG CGTACTGGCA AAGTTATCCA GATACGACGA GGGGACTTTG 
TTTTCTTCGT TTCTGTCATT TACGGTGAAG GCGGCATCTA AGTATGTGGA CGTACCTAAA 
CCCGGGATGG ATGTGGCCGA CGCCTACGTG ACTTTCGTCC GCCACTCTCA GGATGTCCTT 
CGTGATAAGG TCAATGAGGA GATGTATATA GAAAGGTTAT TTGATCAATG GTACAACAGC 
TCCATGAACG TCATCTGCAC CTGGCTGACC GACCGGATGG ACCTCCAGCT TCACATTTAT 
CAGCTGAAAA CACTAATTAG GATGGTAAAG AAAACCTACA GAGATTTCCG ATTGCAAGGG 
GTCCTGGATT CCACCTTAAA CAGCAAGACC TATGAGACCA TTCGAAATCG GCTCACTGTA 
GAGGAACGTA CCGCGTCCGT GAGTGAGGGA GGGGGCTTGC AAGGCATCAG CATGAAGGAC 
AGTGACGAGG AAGATGAAGA AGACGACTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

The Vesicle Priming Factor CAPS Functions as a Homodimer via C2 Domain Interactions to Promote Regulated Vesicle Exocytosis.
The Journal of biological chemistry291(40)21257-21270(2016 Sep)
Petrie M,Esquibel J,Kabachinski G,Maciuba S,Takahashi H,Edwardson JM,Martin TF


book

Resident CAPS on dense-core vesicles docks and primes vesicles for fusion.
Molecular biology of the cell27(4)654-68(2016 Feb)
Kabachinski G,Kielar-Grevstad DM,Zhang X,James DJ,Martin TF


book

CAPS-1 promotes fusion competence of stationary dense-core vesicles in presynaptic terminals of mammalian neurons.
eLife4(2015 Feb)
Farina M,van de Bospoort R,He E,Persoon CM,van Weering JR,Broeke JH,Verhage M,Toonen RF


book

The morphological and molecular nature of synaptic vesicle priming at presynaptic active zones.
Neuron84(2)416-31(2014 Oct)
Imig C,Min SW,Krinner S,Arancillo M,Rosenmund C,S?dhof TC,Rhee J,Brose N,Cooper BH


book

CAPS and Munc13 utilize distinct PIP2-linked mechanisms to promote vesicle exocytosis.
Molecular biology of the cell25(4)508-21(2014 Feb)
Kabachinski G,Yamaga M,Kielar-Grevstad DM,Bruinsma S,Martin TF