Gene Symbol | Fads3 |
Entrez Gene ID | 286922 |
Full Name | fatty acid desaturase 3 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Fads3 cDNA ORF clone
Gene Symbol | Fads3 |
Entrez Gene ID | 286922 |
Full Name | fatty acid desaturase 3 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_173137.1 | NP_775160.1 | fatty acid desaturase 3 |
The 51 kDa FADS3 is secreted in the ECM of hepatocytes and blood in rat.
Blanchard H, Boulier-Month?an N, Legrand P, P?drono F
Journal of cellular biochemistry115(1)199-207(2014 Jan)
Trans-vaccenate is ?13-desaturated by FADS3 in rodents.
Rioux V, P?drono F, Blanchard H, Duby C, Boulier-Month?an N, Bernard L, Beauchamp E, Catheline D, Legrand P
Journal of lipid research54(12)3438-52(2013 Dec)
The fatty acid desaturase 3 gene encodes for different FADS3 protein isoforms in mammalian tissues.
P?drono F, Blanchard H, Kloareg M, D'andr?a S, Daval S, Rioux V, Legrand P
Journal of lipid research51(3)472-9(2010 Mar)
cDNA cloning, genomic structure, and chromosomal localization of three members of the human fatty acid desaturase family.
Marquardt A, St?hr H, White K, Weber BH
Genomics66(2)175-83(2000 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
FADS3 was secreted specifically by hepatocytes in the extracellular matrix where it was located on fibronectin-containing fibers.The 51 kDa FADS3 is secreted in the extracellular matrix of hepatocytes and blood.
Title: The 51 kDa FADS3 is secreted in the ECM of hepatocytes and blood in rat.
FADS3 is the first "methyl-end" fatty acid desaturase functionally characterized in mammals
Title: Trans-vaccenate is ?13-desaturated by FADS3 in rodents.
FADS3 does exist under multiple protein isoforms depending on the mammalian tissues.
Title: The fatty acid desaturase 3 gene encodes for different FADS3 protein isoforms in mammalian tissues.
The following Fads3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fads3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa03538 | |
Clone ID Related Accession (Same CDS sequence) | NM_173137.1 | |
Accession Version | NM_173137.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1350bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-05-27 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | fatty acid desaturase 3 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ494720.1. ##Evidence-Data-START## Transcript exon combination :: AJ494720.1, HQ901598.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGGCGGCG TCGGGGAGCC CGGTGGGGGA CCCGGGCCAC GGGAGGGGCC CGCACCGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_775160.1 |
CDS | 89..1438 |
Translation |
Target ORF information:
Target ORF information:
|
NM_173137.1 |
1 | ATGGGCGGCG TCGGGGAGCC CGGTGGGGGA CCCGGGCCAC GGGAGGGGCC CGCACCGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The 51 kDa FADS3 is secreted in the ECM of hepatocytes and blood in rat. |
Trans-vaccenate is ?13-desaturated by FADS3 in rodents. |
The fatty acid desaturase 3 gene encodes for different FADS3 protein isoforms in mammalian tissues. |
cDNA cloning, genomic structure, and chromosomal localization of three members of the human fatty acid desaturase family. |