Gene Symbol | Ugt2b7 |
Entrez Gene ID | 286989 |
Full Name | UDP glucuronosyltransferase family 2 member B7 |
Synonyms | UDPGT 2B7,Ugt2b8 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Ugt2b7 cDNA ORF clone
Gene Symbol | Ugt2b7 |
Entrez Gene ID | 286989 |
Full Name | UDP glucuronosyltransferase family 2 member B7 |
Synonyms | UDPGT 2B7,Ugt2b8 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_173323.1 | NP_775445.1 | UDP-glucuronosyltransferase 2B7 precursor |
Rattus norvegicus (Norway rat) | Ugt2b7 | NP_775445.1 |
UGT2B4 | XP_001107708.1 | |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP007374 | XP_308459.4 |
Homo sapiens (human) | UGT2B4 | NP_066962.2 |
Pan troglodytes (chimpanzee) | UGT2B4 | XP_001161846.1 |
Acute liver failure enhances oral plasma exposure of zidovudine in rats by downregulation of hepatic UGT2B7 and intestinal P-gp.
Wang F, Miao MX, Sun BB, Wang ZJ, Tang XG, Chen Y, Zhao KJ, Liu XD, Liu L
Acta pharmacologica Sinica38(11)1554-1565(2017 Nov)
Simultaneous evaluation of six human glucuronidation activities in liver microsomes using liquid chromatography-tandem mass spectrometry.
Gagez AL, Rouguieg-Malki K, Sauvage FL, Marquet P, Picard N
Analytical biochemistry427(1)52-9(2012 Aug)
Human UDP-glucuronosyltransferase isoforms involved in haloperidol glucuronidation and quantitative estimation of their contribution.
Kato Y, Nakajima M, Oda S, Fukami T, Yokoi T
Drug metabolism and disposition: the biological fate of chemicals40(2)240-8(2012 Feb)
Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.
Rowbotham SE, Illingworth NA, Daly AK, Veal GJ, Boddy AV
Drug metabolism and disposition: the biological fate of chemicals38(7)1211-7(2010 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data suggest that UGT2B7 is the predominant activity in liver microsomes for haloperidol O-glucuronidation (in both rat and human).
Title: Human UDP-glucuronosyltransferase isoforms involved in haloperidol glucuronidation and quantitative estimation of their contribution.
The following Ugt2b7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ugt2b7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa42331 | |
Clone ID Related Accession (Same CDS sequence) | NM_173323.1 | |
Accession Version | NM_173323.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1593bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-15 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | UDP-glucuronosyltransferase 2B7 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U27518.1. ##Evidence-Data-START## Transcript exon combination :: U27518.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2689597, SAMN01906357 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGCCTCAGA AGTGGATTTC TGCTCTGCTC CTACTGCAGA TAAGTTTCTG CTTCAGATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_775445.1 |
CDS | 27..1619 |
Translation |
Target ORF information:
Target ORF information:
|
NM_173323.1 |
1 | ATGCCTCAGA AGTGGATTTC TGCTCTGCTC CTACTGCAGA TAAGTTTCTG CTTCAGATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Acute liver failure enhances oral plasma exposure of zidovudine in rats by downregulation of hepatic UGT2B7 and intestinal P-gp. |
Simultaneous evaluation of six human glucuronidation activities in liver microsomes using liquid chromatography-tandem mass spectrometry. |
Human UDP-glucuronosyltransferase isoforms involved in haloperidol glucuronidation and quantitative estimation of their contribution. |
Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans. |