Pyy cDNA ORF clone, Rattus norvegicus(Norway rat)
| Gene Symbol | Pyy |
| Entrez Gene ID | 287730 |
| Full Name | peptide YY (mapped) |
| Synonyms | GHYY,RATGHYY,Yy,peptide-YY |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome | |
| Summary | plays a role in regulation of intestinal motility and response to dietary fat intake [RGD, Feb 2006]. |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| XM_017597137.1 | XP_017452626.1 | peptide YY isoform X1 |
| NM_001034080.1 | NP_001029252.1 | peptide YY precursor |
| PYY | XP_001113958.1 | |
| Bos taurus (cattle) | PYY | NP_001035677.1 |
| Rattus norvegicus (Norway rat) | Pyy | NP_001029252.1 |
| Xenopus tropicalis (tropical clawed frog) | pyy | NP_001072427.1 |
| Homo sapiens (human) | PYY | NP_004151.3 |
| Pan troglodytes (chimpanzee) | PYY | XP_523780.3 |
| Danio rerio (zebrafish) | pyya | NP_001157843.1 |
| Canis lupus familiaris (dog) | PYY | XP_005624470.1 |
| Mus musculus (house mouse) | Pyy | NP_663410.1 |
| Danio rerio (zebrafish) | pyyb | XP_001333222.2 |
Related articles in PubMed
Peptide YY mediates the satiety effects of diets enriched with whey protein fractions in male rats.
Zapata RC, Singh A, Chelikani PK
FASEB journal : official publication of the Federation of American Societies for Experimental Biology(2017 Oct)
Glucagon-like peptide-1 (GLP-1) increases in plasma and colon tissue prior to estrus and circulating levels change with increasing age in reproductively competent Wistar rats.
Johnson ML, Saffrey MJ, Taylor VJ
Peptides9055-62(2017 Apr)
PYY-Dependent Restoration of Impaired Insulin and Glucagon Secretion in Type 2 Diabetes following Roux-En-Y Gastric Bypass Surgery.
Ramracheya RD, McCulloch LJ, Clark A, Wiggins D, Johannessen H, Olsen MK, Cai X, Zhao CM, Chen D, Rorsman P
Cell reports15(5)944-950(2016 05)
Tumor-associated energy homeostasis: hepatoblastoma and neuroblastoma affect glucose and lipid metabolism as well as ghrelin, GLP-1, and PYY in nude rats.
Till H, Schlichting N, Oberbach A
European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie25(1)128-31(2015 Feb)
Early-effect of bariatric surgery (Scopinaro method) on intestinal hormones and adipokines in insulin resistant Wistar rat.
Dib N, Kiciak A, Pietrzak P, Ferenc K, Jaworski P, Kapica M, Tarnowski W, Zabielski R
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society64(5)571-7(2013 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Additional analysis of the findings demonstrated significant interactions of ovarian cycle stage and fed/fasted status with age on GLP-1, but not PYY plasma concentrations
Title: Glucagon-like peptide-1 (GLP-1) increases in plasma and colon tissue prior to estrus and circulating levels change with increasing age in reproductively competent Wistar rats.
These findings indicate that the mechanism underlying type 2 diabetes remission may be mediated by PYY.
Title: PYY-Dependent Restoration of Impaired Insulin and Glucagon Secretion in Type 2 Diabetes following Roux-En-Y Gastric Bypass Surgery.
Serum PYY levels were nonsignificantly decreased in rats with human neuroblastoma and hepatoblastoma transplants.
Title: Tumor-associated energy homeostasis: hepatoblastoma and neuroblastoma affect glucose and lipid metabolism as well as ghrelin, GLP-1, and PYY in nude rats.
The early effect of biliopancreatic diversion on resuming insulin resistance in rats may be associated with rapid modification of neurohormonal mechanisms involving PYY, apelin and visfatin, rather than with caloric restriction as proposed recently.
Title: Early-effect of bariatric surgery (Scopinaro method) on intestinal hormones and adipokines in insulin resistant Wistar rat.
gut PYY(3-36) action at Y2 receptors peripheral to the blood brain barrier plays an essential role in mediating satiety
Title: Role of peptide YY(3-36) in the satiety produced by gastric delivery of macronutrients in rats.
The following Pyy gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pyy cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa12988 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001034080.1 | |
| Accession Version | NM_001034080.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 297bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-24 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | peptide YY precursor | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BF551062.1 and AA998735.1. On Oct 13, 2005 this sequence version replaced XM_213468.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB238226.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906347, SAMN01906348 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGTGGCGG TACGCAGGCC TTGGCCCGTT ATGGTCGCAA TGCTGCTTGT CCTGCTCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001029252.1 |
| CDS | 70..366 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001034080.1 |
ORF Insert Sequence:
1 | ATGGTGGCGG TACGCAGGCC TTGGCCCGTT ATGGTCGCAA TGCTGCTTGT CCTGCTCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa57253 | |
| Clone ID Related Accession (Same CDS sequence) | XM_017597137.1 | |
| Accession Version | XM_017597137.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 291bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | peptide YY isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGTGGCGG TACGCAGGCC TTGGCCCGTT ATGGTCGCAA TGCTGCTAGT CCTGCTCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_017452626.1 |
| CDS | 113..403 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_017597137.1 |
ORF Insert Sequence:
1 | ATGGTGGCGG TACGCAGGCC TTGGCCCGTT ATGGTCGCAA TGCTGCTAGT CCTGCTCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
Peptide YY mediates the satiety effects of diets enriched with whey protein fractions in male rats. |
|
Glucagon-like peptide-1 (GLP-1) increases in plasma and colon tissue prior to estrus and circulating levels change with increasing age in reproductively competent Wistar rats. |
|
PYY-Dependent Restoration of Impaired Insulin and Glucagon Secretion in Type 2 Diabetes following Roux-En-Y Gastric Bypass Surgery. |
|
Tumor-associated energy homeostasis: hepatoblastoma and neuroblastoma affect glucose and lipid metabolism as well as ghrelin, GLP-1, and PYY in nude rats. |
|
Early-effect of bariatric surgery (Scopinaro method) on intestinal hormones and adipokines in insulin resistant Wistar rat. |