Gene Symbol | Diablo |
Entrez Gene ID | 288753 |
Full Name | diablo, IAP-binding mitochondrial protein |
Synonyms | Smac |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Diablo cDNA ORF clone
Gene Symbol | Diablo |
Entrez Gene ID | 288753 |
Full Name | diablo, IAP-binding mitochondrial protein |
Synonyms | Smac |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001008292.1 | NP_001008293.1 | diablo homolog, mitochondrial |
Rattus norvegicus (Norway rat) | Diablo | NP_001008293.1 |
Danio rerio (zebrafish) | diablob | NP_001229963.1 |
Danio rerio (zebrafish) | diabloa | NP_956640.1 |
DIABLO | XP_001096967.2 | |
Rattus norvegicus (Norway rat) | LOC100360940 | XP_002729586.2 |
Variations in the protein level of Omi/HtrA2 in the heart of aged rats may contribute to the increased susceptibility of cardiomyocytes to ischemia/reperfusion injury and cell death : Omi/HtrA2 and aged heart injury.
Wang K, Zhang J, Liu J, Tian J, Wu Y, Wang X, Quan L, Xu H, Wang W, Liu H
Age (Dordrecht, Netherlands)35(3)733-46(2013 Jun)
Mitochondrial fission leads to Smac/DIABLO release quenched by ARC.
Li J, Li Y, Qin D, von Harsdorf R, Li P
Apoptosis : an international journal on programmed cell death15(10)1187-96(2010 Oct)
HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex.
Hostager BS, Fox DK, Whitten D, Wilkerson CG, Eipper BA, Francone VP, Rothman PB, Colgan JD
PloS one5(6)e11380(2010 Jun)
[Dynamic changes of Smac/DIABLO protein expression in rat donor myocardium suffered from hypothermic preservation].
Zheng MZ, Jiang JP, Fu L, Zhu L, Chen YY, Shen YL
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology25(3)296-300(2009 Aug)
Effects of endotoxin on liver Smac apoptosis channel.
Chen M, Zhou J, Li H, Chen A, Zhang Z, Tian D
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban28(6)660-4(2008 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Omi/HtrA2, but not Smac/DIABLO, expression was increased in aging hearts.
Title: Variations in the protein level of Omi/HtrA2 in the heart of aged rats may contribute to the increased susceptibility of cardiomyocytes to ischemia/reperfusion injury and cell death : Omi/HtrA2 and aged heart injury.
data reveal that Smac/DIABLO is a target of ARC in counteracting apoptosis
Title: Mitochondrial fission leads to Smac/DIABLO release quenched by ARC.
Prolonged hypothermic preservation of myocardium might lead to the expression of Smac/DIABLO protein and induce cardiomyocyte apoptosis.
Title: [Dynamic changes of Smac/DIABLO protein expression in rat donor myocardium suffered from hypothermic preservation].
Mitochondria signal channel plays an important role in the endotoxin-induced apoptosis of hepatic cells by promoting the release of smac from mitochondria to cytoplasm and activating caspase-9 and caspase-3.
Title: Effects of endotoxin on liver Smac apoptosis channel.
Results describe the role of IAP and Smac/DIABLO in neuronal death.
Title: Role of inhibitor of apoptosis proteins and Smac/DIABLO in staurosporine-induced cerebellar granule neurons death.
The following Diablo gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Diablo cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa11171 | |
Clone ID Related Accession (Same CDS sequence) | NM_001008292.1 | |
Accession Version | NM_001008292.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 714bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-26 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | diablo homolog, mitochondrial | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC086366.1. On Dec 16, 2004 this sequence version replaced XM_213814.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC086366.1, EV763199.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## |
1 | ATGGCGGCTC TGAGGAGTTG GATGACTCGG AGCGTAACCT TTCTGTTCAG GTACGGACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001008293.1 |
CDS | 22..735 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001008292.1 |
1 | ATGGCGGCTC TGAGGAGTTG GATGACTCGG AGCGTAACCT TTCTGTTCAG GTACGGACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Variations in the protein level of Omi/HtrA2 in the heart of aged rats may contribute to the increased susceptibility of cardiomyocytes to ischemia/reperfusion injury and cell death : Omi/HtrA2 and aged heart injury. |
Mitochondrial fission leads to Smac/DIABLO release quenched by ARC. |
HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex. |
[Dynamic changes of Smac/DIABLO protein expression in rat donor myocardium suffered from hypothermic preservation]. |
Effects of endotoxin on liver Smac apoptosis channel. |