Gene Symbol | Usp4 |
Entrez Gene ID | 290864 |
Full Name | ubiquitin specific peptidase 4 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Usp4 cDNA ORF clone
Gene Symbol | Usp4 |
Entrez Gene ID | 290864 |
Full Name | ubiquitin specific peptidase 4 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001106093.2 | NP_001099563.1 | ubiquitin carboxyl-terminal hydrolase 4 isoform b |
NM_001135012.1 | NP_001128484.1 | ubiquitin carboxyl-terminal hydrolase 4 isoform a |
Canis lupus familiaris (dog) | USP4 | XP_003432923.1 |
Gallus gallus (chicken) | USP4 | NP_001006134.1 |
Homo sapiens (human) | USP4 | NP_003354.2 |
USP4 | XP_002802844.1 | |
Bos taurus (cattle) | USP4 | NP_001093789.1 |
Rattus norvegicus (Norway rat) | Usp4 | NP_001128484.1 |
Xenopus tropicalis (tropical clawed frog) | usp4 | XP_002936515.1 |
Pan troglodytes (chimpanzee) | USP4 | XP_001163445.1 |
Danio rerio (zebrafish) | usp4 | XP_002662556.2 |
Mus musculus (house mouse) | Usp4 | NP_035808.2 |
Caenorhabditis elegans (roundworm) | H34C03.2 | NP_501035.1 |
Arabidopsis thaliana (thale cress) | UBP5 | NP_565944.1 |
Downregulation of USP4 Promotes Activation of Microglia and Subsequent Neuronal Inflammation in Rat Spinal Cord After Injury.
Jiang X, Yu M, Ou Y, Cao Y, Yao Y, Cai P, Zhang F
Neurochemical research42(11)3245-3253(2017 Nov)
Increased Expression of Ubiquitin-Specific Protease 4 Participates in Neuronal Apoptosis After Intracerebral Hemorrhage in Adult Rats.
Liu C, Liu C, Liu H, Gong L, Tao T, Shen Y, Zhu S, Shen A
Cellular and molecular neurobiology37(3)427-435(2017 Apr)
Structural variability of the ubiquitin specific protease DUSP-UBL double domains.
Elliott PR, Liu H, Pastok MW, Grossmann GJ, Rigden DJ, Clague MJ, Urb? S, Barsukov IL
FEBS letters585(21)3385-90(2011 Nov)
The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome.
Song EJ, Werner SL, Neubauer J, Stegmeier F, Aspden J, Rio D, Harper JW, Elledge SJ, Kirschner MW, Rape M
Genes & development24(13)1434-47(2010 Jul)
UnpEL/Usp4 is ubiquitinated by Ro52 and deubiquitinated by itself.
Wada K, Kamitani T
Biochemical and biophysical research communications342(1)253-8(2006 Mar)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
USP4 may be involved in neuronal apoptosis after intracerebral hemorrhage.
Title: Increased Expression of Ubiquitin-Specific Protease 4 Participates in Neuronal Apoptosis After Intracerebral Hemorrhage in Adult Rats.
The following Usp4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Usp4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa00165 | |
Clone ID Related Accession (Same CDS sequence) | NM_001106093.2 | |
Accession Version | NM_001106093.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2745bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-30 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | ubiquitin carboxyl-terminal hydrolase 4 isoform b | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC128721.4. On Sep 16, 2008 this sequence version replaced NM_001106093.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052297, SAMEA2689594 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGCGGAAG GCCGGGGCAC CCATGAGCGA CCGGATGTGG AGACCCAGAA GACGGAGCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001099563.1 |
CDS | 25..2769 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001106093.2 |
1 | ATGGCGGAAG GCCGGGGCAC CCATGAGCGA CCGGATGTGG AGACCCAGAA GACGGAGCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa03859 | |
Clone ID Related Accession (Same CDS sequence) | NM_001135012.1 | |
Accession Version | NM_001135012.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2886bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-19 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | ubiquitin carboxyl-terminal hydrolase 4 isoform a | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC128721.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## CDS exon combination :: BC166460.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGCGGAAG GCCGGGGCAC CCATGAGCGA CCGGATGTGG AGACCCAGAA GACGGAGCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001128484.1 |
CDS | 25..2910 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001135012.1 |
1 | ATGGCGGAAG GCCGGGGCAC CCATGAGCGA CCGGATGTGG AGACCCAGAA GACGGAGCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Downregulation of USP4 Promotes Activation of Microglia and Subsequent Neuronal Inflammation in Rat Spinal Cord After Injury. |
Increased Expression of Ubiquitin-Specific Protease 4 Participates in Neuronal Apoptosis After Intracerebral Hemorrhage in Adult Rats. |
Structural variability of the ubiquitin specific protease DUSP-UBL double domains. |
The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome. |
UnpEL/Usp4 is ubiquitinated by Ro52 and deubiquitinated by itself. |